In
psychologyPsychology is the study of the mind and behavior. Its immediate goal is to understand individuals and groups by both establishing general principles and researching specific cases. For many, the ultimate goal of psychology is to benefit society...
,
sensation and
perception are stages of processing of the
senseSenses are physiological capacities of organisms that provide inputs for perception. The senses and their operation, classification, and theory are overlapping topics studied by a variety of fields, most notably neuroscience, cognitive psychology , and philosophy of perception...
s in human and animal systems, such as
visionVisual perception is the ability to interpret information and surroundings from the effects of visible light reaching the eye. The resulting perception is also known as eyesight, sight, or vision...
, auditory, vestibular, and pain senses. These topics are considered part of psychology, and not
anatomyAnatomy is a branch of biology and medicine that is the consideration of the structure of living things. It is a general term that includes human anatomy, animal anatomy , and plant anatomy...
or
physiologyPhysiology is the science of the function of living systems. This includes how organisms, organ systems, organs, cells, and bio-molecules carry out the chemical or physical functions that exist in a living system. The highest honor awarded in physiology is the Nobel Prize in Physiology or...
, because processes in the brain so greatly affect the
perceptionPerception is the process of attaining awareness or understanding of the environment by organizing and interpreting sensory information. All perception involves signals in the nervous system, which in turn result from physical stimulation of the sense organs...
of a stimulus. Included in this topic is the study of illusions such as
motion aftereffectThe motion after-effect is a visual illusion experienced after viewing a moving visual stimulus for a time with stationary eyes, and then fixating a stationary stimulus. The stationary stimulus appears to move in the opposite direction to the original stimulus...
,
color constancyColor constancy is an example of subjective constancy and a feature of the human color perception system which ensures that the perceived color of objects remains relatively constant under varying illumination conditions. A green apple for instance looks green to us at midday, when the main...
,
auditory illusionAn auditory illusion is an illusion of hearing, the aural equivalent of an optical illusion: the listener hears either sounds which are not present in the stimulus, or "impossible" sounds...
s, and
depth perceptionDepth perception is the visual ability to perceive the world in three dimensions and the distance of an object. Depth sensation is the ability to move accurately, or to respond consistently, based on the distances of objects in an environment....
.
Sensation is the function of the low-level biochemical and neurological events that begin with the impinging of a
stimulusIn physiology, a stimulus is a detectable change in the internal or external environment. The ability of an organism or organ to respond to external stimuli is called sensitivity....
upon the receptor cells of a sensory organ.
Perception is the mental process or state that is reflected in statements like "I see a uniformly blue wall", representing awareness or understanding of the real-world cause of the sensory input. The goal of sensation is detection, the goal of perception is to create useful information of the surroundings.
In other words, sensations are the first stages in the functioning of
senseSenses are physiological capacities of organisms that provide inputs for perception. The senses and their operation, classification, and theory are overlapping topics studied by a variety of fields, most notably neuroscience, cognitive psychology , and philosophy of perception...
s to represent stimuli from the environment, and perception is a higher brain function about interpreting events and objects in the world.
Gestalt theorists believe that with the two together a person experiences a personal reality that is greater than the parts.
Senses and receptors
While there is debate among neurologists as to the specific number of senses due to differing definitions of what constitutes a
senseSenses are physiological capacities of organisms that provide inputs for perception. The senses and their operation, classification, and theory are overlapping topics studied by a variety of fields, most notably neuroscience, cognitive psychology , and philosophy of perception...
,
AristotleAristotle was a Greek philosopher and polymath, a student of Plato and teacher of Alexander the Great. His writings cover many subjects, including physics, metaphysics, poetry, theater, music, logic, rhetoric, linguistics, politics, government, ethics, biology, and zoology...
classified five ‘traditional’ human senses which have become universally accepted: touch,
tasteTaste is one of the traditional five senses. It refers to the ability to detect the flavor of substances such as food, certain minerals, and poisons, etc....
,
smellOlfaction is the sense of smell. This sense is mediated by specialized sensory cells of the nasal cavity of vertebrates, and, by analogy, sensory cells of the antennae of invertebrates...
,
sightThe visual system is the part of the central nervous system which enables organisms to process visual detail, as well as enabling several non-image forming photoresponse functions. It interprets information from visible light to build a representation of the surrounding world...
, and
hearingHearing is the ability to perceive sound by detecting vibrations through an organ such as the ear. It is one of the traditional five senses...
. Other senses that have been well-accepted in most mammals, including humans, include
nociceptionNociception is defined as "the neural processes of encoding and processing noxious stimuli." It is the afferent activity produced in the peripheral and central nervous system by stimuli that have the potential to damage tissue...
,
equilibrioceptionEquilibrioception or sense of balance is one of the physiological senses. It helps prevent humans and animals from falling over when walking or standing still. Balance is the result of a number of body systems working together: the eyes , ears and the body's sense of where it is in space ideally...
, kinaesthesia, and
thermoceptionThermoception or thermoreception is the sense by which an organism perceives temperature. The details of how temperature receptors work are still being investigated. Ciliopathy is associated with decreased ability to sense heat, thus cilia may aid in the process...
. Furthermore, some non-human animals have been shown to possess alternate senses, including
magnetoceptionMagnetoception is the ability to detect a magnetic field to perceive direction, altitude or location. This sense plays a role in the navigational abilities of several animal species and has been postulated as a method for animals to develop regional maps.Magnetoception is most commonly observed in...
and
electroreceptionElectroreception is the biological ability to perceive natural electrical stimuli. It has been observed only in aquatic or amphibious animals, since water is a much better conductor than air. Electroreception is used in electrolocation and for electrocommunication.- Overview :Electroreception is...
.
Receptors
The initialization of sensation stems from the response of a specific receptor to a physical
stimulusIn physiology, a stimulus is a detectable change in the internal or external environment. The ability of an organism or organ to respond to external stimuli is called sensitivity....
. The receptors which react to the stimulus and initiate the process of sensation are commonly characterized in four distinct categories: chemoreceptors, photoreceptors, mechanoreceptors, and thermoreceptors. All receptors receive distinct physical stimuli and transduce the signal into an electrical
action potentialIn physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and...
. This action potential then travels along afferent neurons to specific brain regions where it is processed and interpreted.
Chemoreceptors
Chemoreceptors, or chemosensors, detect certain chemical stimuli and transduce that signal into an electrical
action potentialIn physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and...
. There are two primary types of chemoreceptors:
- Distance chemoreceptors are integral to receiving stimuli in the olfactory system
The olfactory system is the sensory system used for olfaction, or the sense of smell. Most mammals and reptiles have two distinct parts to their olfactory system: a main olfactory system and an accessory olfactory system. The main olfactory system detects volatile, airborne substances, while the...
through both olfactory receptor neurons and neurons in the vomeronasal organThe vomeronasal organ , or Jacobson's organ, is an auxiliary olfactory sense organ that is found in many animals. It was discovered by Frederik Ruysch and later by Ludwig Jacobson in 1813....
.
- Direct chemoreceptors include the taste buds in the gustatory system
The gustatory system is the sensory system for the sense of taste.- Importance :The gustatory system allows humans to distinguish between safe and harmful food. Bitter and sour foods we find unpleasant, while salty, sweet, and meaty tasting foods generally provide a pleasurable sensation...
as well as receptors in the aortic bodies which detect changes in oxygenOxygen is the element with atomic number 8 and represented by the symbol O. Its name derives from the Greek roots ὀξύς and -γενής , because at the time of naming, it was mistakenly thought that all acids required oxygen in their composition...
concentration.
Photoreceptors
Photoreceptors are capable of phototransduction, a process which converts light (
electromagnetic radiationElectromagnetic radiation is a form of energy that exhibits wave-like behavior as it travels through space...
) into, among other types of
energyIn physics, energy is an indirectly observed quantity. It is often understood as the ability a physical system has to do work on other physical systems...
, a
membrane potentialMembrane potential is the difference in electrical potential between the interior and exterior of a biological cell. All animal cells are surrounded by a plasma membrane composed of a lipid bilayer with a variety of types of proteins embedded in it...
. There are three primary types of photoreceptors:
ConesCone cells, or cones, are photoreceptor cells in the retina of the eye that are responsible for color vision; they function best in relatively bright light, as opposed to rod cells that work better in dim light. If the retina is exposed to an intense visual stimulus, a negative afterimage will be...
are photoreceptors which respond significantly to
colorColor or colour is the visual perceptual property corresponding in humans to the categories called red, green, blue and others. Color derives from the spectrum of light interacting in the eye with the spectral sensitivities of the light receptors...
. In humans the three different types of cones correspond with a primary response to short wavelength (blue), medium wavelength (green), and long wavelength (yellow/red).
RodsRod cells, or rods, are photoreceptor cells in the retina of the eye that can function in less intense light than can the other type of visual photoreceptor, cone cells. Named for their cylindrical shape, rods are concentrated at the outer edges of the retina and are used in peripheral vision. On...
are photoreceptors which are very sensitive to the intensity of light, allowing for vision in dim lighting. The concentrations and ratio of rods to cones is strongly correlated with whether an animal is diurnal or nocturnal. In humans rods outnumber cones by approximately 20:1, while in nocturnal animals, such as the
tawny owlThe Tawny Owl or Brown Owl is a stocky, medium-sized owl commonly found in woodlands across much of Eurasia. Its underparts are pale with dark streaks, and the upperparts are either brown or grey. Several of the eleven recognised subspecies have both variants...
, the ratio is closer to 1000:1.
Ganglion CellsA retinal ganglion cell is a type of neuron located near the inner surface of the retina of the eye. It receives visual information from photoreceptors via two intermediate neuron types: bipolar cells and amacrine cells...
reside in the
adrenal medullaThe adrenal medulla is part of the adrenal gland. It is located at the center of the gland, being surrounded by the adrenal cortex. It is the innermost part of the adrenal gland, consisting of cells that secrete epinephrine , norepinephrine , and a small amount of dopamine in response to...
and
retinaThe vertebrate retina is a light-sensitive tissue lining the inner surface of the eye. The optics of the eye create an image of the visual world on the retina, which serves much the same function as the film in a camera. Light striking the retina initiates a cascade of chemical and electrical...
where they are involved in the sympathetic response. Of the ~1.3 million ganglion cells present in the retina, 1-2% are believed to be photosensitive.
Mechanoreceptors
Mechanoreceptors are sensory receptors which respond to mechanical forces, such as
pressurePressure is the force per unit area applied in a direction perpendicular to the surface of an object. Gauge pressure is the pressure relative to the local atmospheric or ambient pressure.- Definition :...
or
distortionA distortion is the alteration of the original shape of an object, image, sound, waveform or other form of information or representation. Distortion is usually unwanted, and often many methods are employed to minimize it in practice...
. While mechanoreceptors are present in hair cells and play an integral role in the
vestibularThe vestibular system, which contributes to balance in most mammals and to the sense of spatial orientation, is the sensory system that provides the leading contribution about movement and sense of balance. Together with the cochlea, a part of the auditory system, it constitutes the labyrinth of...
and
auditory systemThe auditory system is the sensory system for the sense of hearing.- Outer ear :The folds of cartilage surrounding the ear canal are called the pinna...
, the majority of mechanoreceptors are cutaneous and are grouped into four categories:
Slowly Adapting type 1 Receptors have small receptive fields and respond to static stimulation. These receptors are primarily used in the sensations of
formThe shape of an object located in some space is a geometrical description of the part of that space occupied by the object, as determined by its external boundary – abstracting from location and orientation in space, size, and other properties such as colour, content, and material...
and roughness.
Slowly Adapting type 2 Receptors have large receptive fields and respond to stretch. Similarly to type 1, they produce sustained responses to a continued stimuli.
Rapidly Adapting Receptors have small receptive fields and underlie the perception of slip.
Pacinian Receptors have large receptive fields and are the predominant receptors for high frequency vibration.
Thermoreceptors
Thermoreceptors are sensory receptors which respond to varying temperatures. While the mechanisms through which these receptors operate is unclear, recent discoveries have shown that mammals have at least two distinct types of themoreceptors:
The End-Bulb of Krause, or
bulboid corpuscleThe bulboid corpuscles are cutaneous receptors in the human body.The end-bulbs of Krause were named after German anatomist Wilhelm Krause .-Structure:...
, detects temperatures above body temperature
Ruffini’s end organ detects temperatures below body temperature
Sensory cortex
All
stimuliIn physiology, a stimulus is a detectable change in the internal or external environment. The ability of an organism or organ to respond to external stimuli is called sensitivity....
received by the receptors listed above are
transducedSignal transduction occurs when an extracellular signaling molecule activates a cell surface receptor. In turn, this receptor alters intracellular molecules creating a response...
to an
action potentialIn physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and...
, which is carried along one or more afferent neurons towards a specific area of the brain. While the term
sensory cortexThe sensory cortex can refer informally to the primary somatosensory cortex, or it can be used as an umbrella term for the primary and secondary cortices of the different senses : the visual cortex on the occipital lobes, the auditory cortex on the temporal lobes, the primary olfactory cortex on...
is often used informally to refer to the somatosensory cortex, the term more accurately refers to the multiple areas of the brain at which senses are received to be processed. For the five traditional senses in humans, this includes the primary and secondary
cortexes of the different sensesThe sensory cortex can refer informally to the primary somatosensory cortex, or it can be used as an umbrella term for the primary and secondary cortices of the different senses : the visual cortex on the occipital lobes, the auditory cortex on the temporal lobes, the primary olfactory cortex on...
: the somatosensory cortex, the
visual cortexThe visual cortex of the brain is the part of the cerebral cortex responsible for processing visual information. It is located in the occipital lobe, in the back of the brain....
, the auditory cortex, the
primary olfactory cortexThe Primary olfactory cortex is a portion of the cortex involved in olfaction.Some sources state that it includes the prepyriform area and entorhinal area.Other sources state that it consists of the prepiriform cortex and periamygdaloid cortex....
, and the
gustatory cortexThe primary gustatory cortex is a brain structure responsible for the perception of taste. It consists of two substructures: the anterior insula on the insular lobe and the frontal operculum on the inferior frontal gyrus of the frontal lobe. Because of its composition the primary gustatory cortex...
.
Somatosensory cortex
Located in the
parietal lobeThe parietal lobe is a part of the Brain positioned above the occipital lobe and behind the frontal lobe.The parietal lobe integrates sensory information from different modalities, particularly determining spatial sense and navigation. For example, it comprises somatosensory cortex and the...
, the somatosensory cortex is the primary receptive area for the sense of touch. This cortex is further divided into Brodmann areas 1, 2, and 3. Brodmann area 3 is considered the primary processing center of the somatosensory cortex as it receives significantly more input from the
thalamusThe thalamus is a midline paired symmetrical structure within the brains of vertebrates, including humans. It is situated between the cerebral cortex and midbrain, both in terms of location and neurological connections...
, has neurons highly responsive to somatosensory stimuli, and can evoke somatic sensations through electrical
stimulationStimulation is the action of various agents on nerves, muscles, or a sensory end organ, by which activity is evoked; especially, the nervous impulse produced by various agents on nerves, or a sensory end organ, by which the part connected with the nerve is thrown into a state of activity.The word...
. Areas 1 and 2 receive most of their input from area 3.
Visual cortex
The visual cortex refers to the primary visual cortex, labeled V1 or Brodmann area 17, as well as the extrastriate visual cortical areas V2-V5. Located in the
occipital lobeThe occipital lobe is the visual processing center of the mammalian brain containing most of the anatomical region of the visual cortex. The primary visual cortex is Brodmann area 17, commonly called V1...
, V1 acts as the primary relay station for visual input, transmitting information to two primary pathways labeled the dorsal and ventral streams. The dorsal stream includes areas V2 and V5, and is used in interpreting visual ‘where’ and ‘how.’ The ventral stream includes areas V2 and V4, and is used in interpreting ‘what.’
Auditory cortex
Located in the
temporal lobeThe temporal lobe is a region of the cerebral cortex that is located beneath the Sylvian fissure on both cerebral hemispheres of the mammalian brain....
, the auditory cortex is the primary receptive area for sound information. The auditory cortex is composed of Brodmann areas 41 and 42, also known as the anterior transverse temporal area 41 and the posterior transverse temporal area 42, respectively. Both areas act similarly and are integral in receiving and processing the signals transmitted from
auditory receptorsHair cells are the sensory receptors of both the auditory system and the vestibular system in all vertebrates. In mammals, the auditory hair cells are located within the organ of Corti on a thin basilar membrane in the cochlea of the inner ear...
.
Primary olfactory cortex
Located in the temporal lobe, the
primary olfactory cortexThe Primary olfactory cortex is a portion of the cortex involved in olfaction.Some sources state that it includes the prepyriform area and entorhinal area.Other sources state that it consists of the prepiriform cortex and periamygdaloid cortex....
is the primary receptive area for
olfactionOlfaction is the sense of smell. This sense is mediated by specialized sensory cells of the nasal cavity of vertebrates, and, by analogy, sensory cells of the antennae of invertebrates...
. Unique to the olfactory and gustatory systems, at least in mammals, is the implementation of both
peripheralThe peripheral nervous system consists of the nerves and ganglia outside of the brain and spinal cord. The main function of the PNS is to connect the central nervous system to the limbs and organs. Unlike the CNS, the PNS is not protected by the bone of spine and skull, or by the blood–brain...
and
centralThe central nervous system is the part of the nervous system that integrates the information that it receives from, and coordinates the activity of, all parts of the bodies of bilaterian animals—that is, all multicellular animals except sponges and radially symmetric animals such as jellyfish...
mechanisms of action. The peripheral mechanisms involve olfactory receptor neurons which
transduceSignal transduction occurs when an extracellular signaling molecule activates a cell surface receptor. In turn, this receptor alters intracellular molecules creating a response...
a chemical signal along the
olfactory nerveThe olfactory nerve, or cranial nerve I, is the first of twelve cranial nerves. It is instrumental in the sense of smell. Derived from the embryonic nasal placode, the olfactory nerve is capable of regeneration.-Anatomy:...
, which terminates in the
olfactory bulbThe olfactory bulb is a structure of the vertebrate forebrain involved in olfaction, the perception of odors.-Anatomy:In most vertebrates, the olfactory bulb is the most rostral part of the brain. In humans, however, the olfactory bulb is on the inferior side of the brain...
. The central mechanisms include the convergance of olfactory nerve
axonsAn axon is a long, slender projection of a nerve cell, or neuron, that conducts electrical impulses away from the neuron's cell body or soma....
into
glomeruliA glomerulus is a capillary tuft that is involved in the first step of filtering blood to form urine.A glomerulus is surrounded by Bowman's capsule, the beginning component of nephrons in the vertebrate kidney. A glomerulus receives its blood supply from an afferent arteriole of the renal...
in the olfactory bulb, where the signal is then transmitted to the
anterior olfactory nucleusThe anterior olfactory nucleus is a portion of the forebrain of vertebrates.It is involved in olfaction.-Location:...
, the
piriform cortexIn anatomy of animals, the piriform cortex, or pyriform cortex is a region in the brain.-Anatomy and function:The piriform cortex is part of the rhinencephalon situated in the telencephalon....
, the medial
amygdalaThe ' are almond-shaped groups of nuclei located deep within the medial temporal lobes of the brain in complex vertebrates, including humans. Shown in research to perform a primary role in the processing and memory of emotional reactions, the amygdalae are considered part of the limbic system.-...
, and the
entorhinal cortexThe entorhinal cortex is located in the medial temporal lobe and functions as a hub in a widespread network for memory and navigation. The EC is the main interface between the hippocampus and neocortex...
, all of which make up the primary olfactory cortex.
Gustatory cortex
The
gustatory cortexThe primary gustatory cortex is a brain structure responsible for the perception of taste. It consists of two substructures: the anterior insula on the insular lobe and the frontal operculum on the inferior frontal gyrus of the frontal lobe. Because of its composition the primary gustatory cortex...
is the primary receptive area for taste, or gustation. The gustatory cortex consists of two primary structures: the
anterior insulaIn each hemisphere of the mammalian brain the insular cortex is a portion of the cerebral cortex folded deep within the lateral sulcus between the temporal lobe and the frontal lobe. The cortical area overlying it towards the lateral surface of the brain is the operculum...
, located on the
insular lobeIn each hemisphere of the mammalian brain the insular cortex is a portion of the cerebral cortex folded deep within the lateral sulcus between the temporal lobe and the frontal lobe. The cortical area overlying it towards the lateral surface of the brain is the operculum...
, and the frontal
operculumOperculum, derived from Latin, meaning "little lid", refers to the cerebral cortex on the outside surface of the brain bordering the lateral sulcus, and the roof and floor of the lateral sulcus. Neuroscience divides the operculum into orbital, frontal, parietal and temporal regions, after the...
, located on the
frontal lobeThe frontal lobe is an area in the brain of humans and other mammals, located at the front of each cerebral hemisphere and positioned anterior to the parietal lobe and superior and anterior to the temporal lobes...
. Similarly to the olfactory cortex, the gustatory pathway operates through both peripheral and central mechanisms. Peripheral
taste receptorsA Taste receptor is a type of receptor which facilitates the sensation of taste.Examples include TAS2R16 and TAS2R38.They are divided into two families:* Type 1, sweet, first characterized in 2001: –...
, located on the
tongueThe tongue is a muscular hydrostat on the floors of the mouths of most vertebrates which manipulates food for mastication. It is the primary organ of taste , as much of the upper surface of the tongue is covered in papillae and taste buds. It is sensitive and kept moist by saliva, and is richly...
,
soft palateThe soft palate is the soft tissue constituting the back of the roof of the mouth. The soft palate is distinguished from the hard palate at the front of the mouth in that it does not contain bone....
,
pharynxThe human pharynx is the part of the throat situated immediately posterior to the mouth and nasal cavity, and anterior to the esophagus and larynx. The human pharynx is conventionally divided into three sections: the nasopharynx , the oropharynx , and the laryngopharynx...
, and
esophagusThe esophagus is an organ in vertebrates which consists of a muscular tube through which food passes from the pharynx to the stomach. During swallowing, food passes from the mouth through the pharynx into the esophagus and travels via peristalsis to the stomach...
, transmit the received signal to primary sensory axons, where the signal is projected to the nucleus of the solitary tract in the
medullaThe medulla oblongata is the lower half of the brainstem. In discussions of neurology and similar contexts where no ambiguity will result, it is often referred to as simply the medulla...
, or the gustatory nucleus of the solitary tract complex. The signal is then transmitted to the
thalamusThe thalamus is a midline paired symmetrical structure within the brains of vertebrates, including humans. It is situated between the cerebral cortex and midbrain, both in terms of location and neurological connections...
, which in turn projects the signal to several regions of the
neocortexThe neocortex , also called the neopallium and isocortex , is a part of the brain of mammals. It is the outer layer of the cerebral hemispheres, and made up of six layers, labelled I to VI...
, including the gustatory cortex.
Loss of sensation
Many types of sense loss occur due to a dysfunctional sensation process, whether it be ineffective receptors,
nerve damageNerve Damage is a compilation album by Groove Metal band Skinlab, released in 2004. It is a 2CD collection of rare and unreleased material, including a live set, demos, remixes, alternate mixes, and two new tracks.-Disc 1:# "Losing All" – 4:04...
, or cerebral impairment. Unlike
agnosiaAgnosia is a loss of ability to recognize objects, persons, sounds, shapes, or smells while the specific sense is not defective nor is there any significant memory loss...
, these impairments are due to damages prior to the
perceptionPerception is the process of attaining awareness or understanding of the environment by organizing and interpreting sensory information. All perception involves signals in the nervous system, which in turn result from physical stimulation of the sense organs...
process.
Vision loss
Degrees of
vision lossVision loss or visual loss is the absence of vision where it existed before, which can happen either acutely or chronically .-Ranges of vision loss:...
vary dramatically, although the ICD-9 released in 1979 categorized them into three tiers: normal vision,
low visionLow vision is a subspecialty within the professions of optometry and ophthalmology dealing with individuals who have reduced vision even when using the best possible spectacle or contact lens correction available. It can be a result of either congenital disease Low vision is a subspecialty within...
, and
blindnessBlindness is the condition of lacking visual perception due to physiological or neurological factors.Various scales have been developed to describe the extent of vision loss and define blindness...
. Two significant causes of vision loss due to sensory failures include media opacity and
optic nerveThe optic nerve, also called cranial nerve 2, transmits visual information from the retina to the brain. Derived from the embryonic retinal ganglion cell, a diverticulum located in the diencephalon, the optic nerve doesn't regenerate after transection.-Anatomy:The optic nerve is the second of...
diseases, although
hypoxiaHypoxia, or hypoxiation, is a pathological condition in which the body as a whole or a region of the body is deprived of adequate oxygen supply. Variations in arterial oxygen concentrations can be part of the normal physiology, for example, during strenuous physical exercise...
and retinal disease can also lead to blindness. Most causes of vision loss can cause varying degrees of damage, from total blindness to a negligible effect.
Media Opacity occurs in the presence of
opacitiesOpacity is the measure of impenetrability to electromagnetic or other kinds of radiation, especially visible light. In radiative transfer, it describes the absorption and scattering of radiation in a medium, such as a plasma, dielectric, shielding material, glass, etc...
in the eye
mediaA growth medium or culture medium is a liquid or gel designed to support the growth of microorganisms or cells, or small plants like the moss Physcomitrella patens.There are different types of media for growing different types of cells....
, distorting and/or blocking the
imageAn image is an artifact, for example a two-dimensional picture, that has a similar appearance to some subject—usually a physical object or a person.-Characteristics:...
prior to contact with the photoreceptor cells. Vision loss due to media opacity often results despite correctly functioning retinal receptors.
Optic Nerve Diseases such as
optic neuritisOptic neuritis is the inflammation of the optic nerve that may cause a complete or partial loss of vision.-Causes:The optic nerve comprises axons that emerge from the retina of the eye and carry visual information to the primary visual nuclei, most of which is relayed to the occipital cortex of the...
or retrobulbar neuritis lead to dysfunction in the afferent nerve pathway once the signal has been correctly transmitted from retinal photoreceptors.
Hearing loss
Similarly to vision loss, hearing loss can vary from full or partial inability to detect some or all frequencies of sound which can typically be heard by members of their
speciesIn biology, a species is one of the basic units of biological classification and a taxonomic rank. A species is often defined as a group of organisms capable of interbreeding and producing fertile offspring. While in many cases this definition is adequate, more precise or differing measures are...
. For humans, this range is approximately 20
HzThe hertz is the SI unit of frequency defined as the number of cycles per second of a periodic phenomenon. One of its most common uses is the description of the sine wave, particularly those used in radio and audio applications....
to 20 kHz at ~6.5
dBThe decibel is a logarithmic unit that indicates the ratio of a physical quantity relative to a specified or implied reference level. A ratio in decibels is ten times the logarithm to base 10 of the ratio of two power quantities...
, although a 10 dB correction is often allowed for the elderly. Primary causes of hearing loss due to an impaired sensory system include long-term exposure to
environmental noiseEnvironmental noise is the summary of noise from transport, industrial and recreational activities.The definition is pursuant to the directive 2002/49/EC article 10.1. This directive should give a common approach intended to avoid, prevent or reduce the harmful effects of environmental noise. The...
, which can damage the mechanoreceptors responsible for receiving
sound vibrationsSound is a mechanical wave that is an oscillation of pressure transmitted through a solid, liquid, or gas, composed of frequencies within the range of hearing and of a level sufficiently strong to be heard, or the sensation stimulated in organs of hearing by such vibrations.-Propagation of...
, as well as multiple diseases, such as
HIVHuman immunodeficiency virus is a lentivirus that causes acquired immunodeficiency syndrome , a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive...
or
meningitisMeningitis is inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. The inflammation may be caused by infection with viruses, bacteria, or other microorganisms, and less commonly by certain drugs...
, which damage the
cochleaThe cochlea is the auditory portion of the inner ear. It is a spiral-shaped cavity in the bony labyrinth, making 2.5 turns around its axis, the modiolus....
and auditory nerve, respectively.
Anosmia
Primary causes of
anosmiaAnosmia is a lack of functioning olfaction, or in other words, an inability to perceive odors. Anosmia may be either temporary or permanent. A related term, hyposmia, refers to a decreased ability to smell, while hyperosmia refers to an increased ability to smell. Some people may be anosmic for one...
, a loss of smell, due to sensory damage involve the death of olfactory receptor neurons, often from nasal polyps or upper respiratory tract infections, as well as damage to the olfactory nerve, often from
hypothyroidismHypothyroidism is a condition in which the thyroid gland does not make enough thyroid hormone.Iodine deficiency is the most common cause of hypothyroidism worldwide but it can be caused by other causes such as several conditions of the thyroid gland or, less commonly, the pituitary gland or...
or
physical traumaTrauma refers to "a body wound or shock produced by sudden physical injury, as from violence or accident." It can also be described as "a physical wound or injury, such as a fracture or blow." Major trauma can result in secondary complications such as circulatory shock, respiratory failure and death...
. Unfortunately, anosmia is strongly correlated with a loss of taste.
Somatosensory loss
Insensitivity to somatosensory stimuli, such as
heatIn physics and thermodynamics, heat is energy transferred from one body, region, or thermodynamic system to another due to thermal contact or thermal radiation when the systems are at different temperatures. It is often described as one of the fundamental processes of energy transfer between...
,
coldCold describes the condition of low temperature.Cold may also refer to:*Common cold, a contagious viral infectious disease of the upper respiratory system*Chronic obstructive pulmonary disease...
, touch, and
painPain is an unpleasant sensation often caused by intense or damaging stimuli such as stubbing a toe, burning a finger, putting iodine on a cut, and bumping the "funny bone."...
, are most commonly a result of a more general physical impairment associated with
paralysisParalysis is loss of muscle function for one or more muscles. Paralysis can be accompanied by a loss of feeling in the affected area if there is sensory damage as well as motor. A study conducted by the Christopher & Dana Reeve Foundation, suggests that about 1 in 50 people have been diagnosed...
. Damage to the
spinal cordThe spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the brain . The brain and spinal cord together make up the central nervous system...
or other major
nerve fiberA nerve fiber is a threadlike extension of a nerve cell and consists of an axon and myelin sheath in the nervous system. There are nerve fibers in the central nervous system and peripheral nervous system. A nerve fiber may be myelinated and/or unmyelinated. In the central nervous system , myelin...
may lead to a termination of both
afferentIn the nervous system, afferent neurons , carry nerve impulses from receptors or sense organs towards the central nervous system. This term can also be used to describe relative connections between structures. Afferent neurons communicate with specialized interneurons...
and
efferentIn the nervous system, efferent nerves, otherwise known as motor or effector neurons, carry nerve impulses away from the central nervous system to effectors such as muscles or glands...
signals to varying areas of the body, causing both a loss of touch and a loss of
motor coordinationthumb|right|Motor coordination is shown in this animated sequence by [[Eadweard Muybridge]] of himself throwing a diskMotor coordination is the combination of body movements created with the kinematic and kinetic parameters that result in intended actions. Such movements usually smoothly and...
. Other types of somatosensory loss include
hereditary sensory and autonomic neuropathyHereditary sensory and autonomic neuropathy or hereditary sensory neuropathy is a condition used to describe any of the types of this disease which inhibit sensation.They are less common than Charcot-Marie-Tooth disease....
, which consists of ineffective afferent neurons with fully functioning efferent neurons; essentially, motor movement without somatosensation.
Ageusia
Taste loss can vary from true aguesia, a complete loss of taste, to
hypogeusiaHypogeusia is a reduced ability to taste things . The complete lack of taste is referred to as ageusia.Causes of hypogeusia include the chemotherapy drug bleomycin, an antitumor antibiotic....
, a partial loss of taste, to
dysgeusiaDysgeusia is the distortion of the sense of taste. Dysgeusia is also often associated with ageusia, which is the complete lack of taste, and hypogeusia, which is the decrease in taste sensitivity. An alteration in taste or smell may be a secondary process in various disease states, or it may be...
, a distortion or alteration of taste. The primary cause of ageusia involves damage to the
lingual nerveThe lingual nerve is a branch of the mandibular nerve , itself a branch of the trigeminal nerve, which supplies sensory innervation to the tongue...
, which receives the stimuli from taste buds for the front two-thirds of the
tongueThe tongue is a muscular hydrostat on the floors of the mouths of most vertebrates which manipulates food for mastication. It is the primary organ of taste , as much of the upper surface of the tongue is covered in papillae and taste buds. It is sensitive and kept moist by saliva, and is richly...
, or the
glossopharyngeal nerveThe glossopharyngeal nerve is the ninth of twelve pairs of cranial nerves . It exits the brainstem out from the sides of the upper medulla, just rostral to the vagus nerve...
, which acts similarly for the back third. Damage may be due to neurological disorders, such as Bell’s palsy or
multiple sclerosisMultiple sclerosis is an inflammatory disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring as well as a broad spectrum of signs and symptoms...
, as well as infectious diseases such as meningoencephalopathy. Other causes include a vitamin B deficiency, as well as taste bud death due to acidic/spicy foods,
radiationIn physics, radiation is a process in which energetic particles or energetic waves travel through a medium or space. There are two distinct types of radiation; ionizing and non-ionizing...
, and/or
tobaccoTobacco is an agricultural product processed from the leaves of plants in the genus Nicotiana. It can be consumed, used as a pesticide and, in the form of nicotine tartrate, used in some medicines...
use.