List of EC numbers (EC 1)
Encyclopedia
This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology
International Union of Biochemistry and Molecular Biology
The International Union of Biochemistry and Molecular Biology is an international non-governmental organisation concerned with biochemistry and molecular biology...

.

EC 1.1.1 With NAD
NAD
NAD may refer to:* No abnormality detected, a medical status description* No apparent distress, a status description in childbirth* NAD Electronics, a Canadian audio equipment manufacturer...

 or NADP as acceptor

: alcohol dehydrogenase
Alcohol dehydrogenase
Alcohol dehydrogenases are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide...

: alcohol dehydrogenase (NADP+): homoserine dehydrogenase
Homoserine dehydrogenase
In enzymology, a homoserine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-homoserine, NAD+, and NADP+, whereas its 4 products are L-aspartate 4-semialdehyde, NADH, NADPH, and H+....

: (R,R)-butanediol dehydrogenase
(R,R)-butanediol dehydrogenase
In enzymology, a -butanediol dehydrogenase is an enzyme that catalyzes the chemical reaction-butane-2,3-diol + NAD+ \rightleftharpoons -acetoin + NADH + H+...

: acetoin dehydrogenase
Acetoin dehydrogenase
Acetoin dehydrogenase or diacetyl reductase is an enzyme that catalyzes the transformation of acetoin to diacetyl....

: glycerol dehydrogenase
Glycerol dehydrogenase
In enzymology, a glycerol dehydrogenase is an enzyme that catalyzes the chemical reaction:Thus, the two substrates of this enzyme are glycerol and NAD+, whereas its three products are glycerone, NADH, and H+....

: propanediol-phosphate dehydrogenase
Propanediol-phosphate dehydrogenase
In enzymology, a propanediol-phosphate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD+, whereas its 3 products are hydroxyacetone phosphate, NADH, and H+....

: glycerol-3-phosphate dehydrogenase (NAD+)
Glycerol-3-phosphate dehydrogenase (NAD+)
In enzymology, a glycerol-3-phosphate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are sn-glycerol 3-phosphate and NAD+, whereas its 3 products are glycerone phosphate, NADH, and H+....

: D-xylulose reductase
D-xylulose reductase
In enzymology, a D-xylulose reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are xylitol and NAD+, whereas its 3 products are D-xylulose, NADH, and H+....

: L-xylulose reductase
L-xylulose reductase
L-xylulose reductase is an enzyme responsible for the metabolism of xylulose, converting it into xylitol....

: D-arabinitol 4-dehydrogenase
D-arabinitol 4-dehydrogenase
In enzymology, a D-arabinitol 4-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-arabinitol and NAD+, whereas its 3 products are D-xylulose, NADH, and H+....

: L-arabinitol 4-dehydrogenase
L-arabinitol 4-dehydrogenase
In enzymology, a L-arabinitol 4-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-arabinitol and NAD+, whereas its 3 products are L-xylulose, NADH, and H+....

: L-arabinitol 2-dehydrogenase
L-arabinitol 2-dehydrogenase
In enzymology, a L-arabinitol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-arabinitol and NAD+, whereas its 3 products are L-ribulose, NADH, and H+....

: L-iditol 2-dehydrogenase
L-iditol 2-dehydrogenase
In enzymology, a L-iditol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-iditol and NAD+, whereas its 3 products are L-sorbose, NADH, and H+....

: D-iditol 2-dehydrogenase
D-iditol 2-dehydrogenase
In enzymology, a D-iditol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-iditol and NAD+, whereas its 3 products are D-sorbose, NADH, and H+....

: galactitol 2-dehydrogenase
Galactitol 2-dehydrogenase
In enzymology, a galactitol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are galactitol and NAD+, whereas its 3 products are D-tagatose, NADH, and H+....

: mannitol-1-phosphate 5-dehydrogenase
Mannitol-1-phosphate 5-dehydrogenase
In enzymology, a mannitol-1-phosphate 5-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-mannitol 1-phosphate and NAD+, whereas its 3 products are fructose 6-phosphate, NADH and H+....

: inositol 2-dehydrogenase
Inositol 2-dehydrogenase
In enzymology, an inositol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are myo-inositol and NAD+, whereas its 3 products are 2,4,6/3,5-pentahydroxycyclohexanone, NADH, and H+....

: L-glucuronate reductase: glucuronolactone reductase
Glucuronolactone reductase
In enzymology, a glucuronolactone reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-gulono-1,4-lactone and NADP+, whereas its 3 products are D-glucurono-3,6-lactone, NADPH, and H+....

: aldehyde reductase: UDP-glucose 6-dehydrogenase
UDP-glucose 6-dehydrogenase
In enzymology, an UDP-glucose 6-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are UDP-glucose, NAD+, and H2O, whereas its 3 products are UDP-glucuronate, NADH, and H+....

: histidinol dehydrogenase
Histidinol dehydrogenase
In enzymology, a histidinol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-histidinol and NAD+, whereas its 3 products are L-histidine, NADH, and H+....

: quinate dehydrogenase
Quinate dehydrogenase
In enzymology, a quinate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-quinate and NAD+, whereas its 3 products are 3-dehydroquinate, NADH, and H+....

: shikimate dehydrogenase
Shikimate dehydrogenase
In enzymology, a shikimate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are shikimate and NADP+, whereas its 3 products are 3-dehydroshikimate, NADPH, and H+....

: glyoxylate reductase
Glyoxylate reductase
In enzymology, a glyoxylate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glycolate and NAD+, whereas its 3 products are glyoxylate, NADH, and H+....

: L-lactate dehydrogenase: D-lactate dehydrogenase: glycerate dehydrogenase
Glycerate dehydrogenase
In enzymology, a glycerate dehydrogenase is an enzyme that catalyzes the chemical reaction-glycerate + NAD+ \rightleftharpoons hydroxypyruvate + NADH + H+...

: 3-hydroxybutyrate dehydrogenase
3-hydroxybutyrate dehydrogenase
In enzymology, a 3-hydroxybutyrate dehydrogenase is an enzyme that catalyzes the chemical reaction-3-hydroxybutanoate + NAD+ \rightleftharpoons acetoacetate + NADH + H+...

: 3-hydroxyisobutyrate dehydrogenase
3-hydroxyisobutyrate dehydrogenase
In enzymology, a 3-hydroxyisobutyrate dehydrogenase also known as β-hydroxyisobutyrate dehydrogenase or 3-hydroxyisobutyrate dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the HIBADH gene....

: mevaldate reductase
Mevaldate reductase
In enzymology, a mevaldate reductase is an enzyme that catalyzes the chemical reaction-mevalonate + NAD+ \rightleftharpoons mevaldate + NADH + H+...

: mevaldate reductase (NADPH)
Mevaldate reductase (NADPH)
In enzymology, a mevaldate reductase is an enzyme that catalyzes the chemical reaction-mevalonate + NADP+ \rightleftharpoons mevaldate + NADPH + H+...

: hydroxymethylglutaryl-CoA reductase (NADPH)
Hydroxymethylglutaryl-CoA reductase (NADPH)
In enzymology, a hydroxymethylglutaryl-CoA reductase is an enzyme that catalyzes the chemical reaction-mevalonate + CoA + 2 NADP+ \rightleftharpoons -3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+...

: 3-hydroxyacyl-CoA dehydrogenase
3-hydroxyacyl-CoA dehydrogenase
In enzymology, a 3-hydroxyacyl-CoA dehydrogenase is an enzyme that catalyzes the chemical reaction-3-hydroxyacyl-CoA + NAD+ \rightleftharpoons 3-oxoacyl-CoA + NADH + H+...

: acetoacetyl-CoA reductase
Acetoacetyl-CoA reductase
In enzymology, an acetoacetyl-CoA reductase is an enzyme that catalyzes the chemical reaction-3-hydroxyacyl-CoA + NADP+ \rightleftharpoons 3-oxoacyl-CoA + NADPH + H+...

: malate dehydrogenase
Malate dehydrogenase
Malate dehydrogenase is an enzyme in the citric acid cycle that catalyzes the conversion of malate into oxaloacetate and vice versa...

: malate dehydrogenase (oxaloacetate-decarboxylating)
Malate dehydrogenase (oxaloacetate-decarboxylating)
In enzymology, a malate dehydrogenase is an enzyme that catalyzes the chemical reaction-malate + NAD+ \rightleftharpoons pyruvate + CO2 + NADH...

: malate dehydrogenase (decarboxylating)
Malate dehydrogenase (decarboxylating)
Malic enzyme , not to be confused with malate dehydrogenase , is an enzyme that catalyzes the chemical reaction-malate + NADP+ \rightleftharpoons pyruvate + CO2 + NADPH...

: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
In enzymology, a malate dehydrogenase is an enzyme that catalyzes the chemical reaction-malate + NADP+ \rightleftharpoons pyruvate + CO2 + NADPH...

: isocitrate dehydrogenase (NAD+): isocitrate dehydrogenase (NADP+): phosphogluconate 2-dehydrogenase
Phosphogluconate 2-dehydrogenase
In enzymology, a phosphogluconate 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 6-phospho-D-gluconic acid, NAD+, and NADP+, whereas its 4 products are 6-phospho-2-dehydro-D-gluconic acid, NADH, NADPH, and H+.This enzyme belongs to the family...

: phosphogluconate dehydrogenase (decarboxylating)
Phosphogluconate dehydrogenase (decarboxylating)
In enzymology, a phosphogluconate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 6-phospho-D-gluconate and NADP+, whereas its 3 products are D-ribulose 5-phosphate, CO2, and NADPH....

: L-gulonate 3-dehydrogenase
L-gulonate 3-dehydrogenase
In enzymology, a L-gulonate 3-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-gulonate and NAD+, whereas its 3 products are 3-dehydro-L-gulonate, NADH, and H+....

: L-arabinose 1-dehydrogenase
L-arabinose 1-dehydrogenase
In enzymology, a L-arabinose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-arabinose and NAD+, whereas its 3 products are L-arabinono-1,4-lactone, NADH, and H+....

: glucose 1-dehydrogenase
Glucose 1-dehydrogenase
In enzymology, a glucose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are beta-D-glucose, NAD+, and NADP+, whereas its 4 products are D-glucono-1,5-lactone, NADH, NADPH, and H+....

: galactose 1-dehydrogenase
Galactose 1-dehydrogenase
In enzymology, a galactose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-galactose and NAD+, whereas its 3 products are D-galactono-1,4-lactone, NADH, and H+....

: glucose-6-phosphate dehydrogenase
Glucose-6-phosphate dehydrogenase
Glucose-6-phosphate dehydrogenase is a cytosolic enzyme in the pentose phosphate pathway , a metabolic pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate...

: 3a-hydroxysteroid dehydrogenase (B-specific): 3(or 17)b-hydroxysteroid dehydrogenase: 3a-hydroxycholanate dehydrogenase: 3a(or 20b)-hydroxysteroid dehydrogenase: allyl-alcohol dehydrogenase
Allyl-alcohol dehydrogenase
In enzymology, an allyl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are allyl alcohol and NADP+, whereas its 3 products are acrolein, NADPH, and H+....

: lactaldehyde reductase (NADPH)
Lactaldehyde reductase (NADPH)
In enzymology, a lactaldehyde reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1,2-propanediol and NADP+, whereas its 3 products are L-lactaldehyde, NADPH, and H+....

: ribitol 2-dehydrogenase
Ribitol 2-dehydrogenase
In enzymology, a ribitol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are ribitol and NAD+, whereas its 3 products are D-ribulose, NADH, and H+....

: fructuronate reductase
Fructuronate reductase
In enzymology, a fructuronate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-mannonate and NAD+, whereas its 3 products are D-fructuronate, NADH, and H+....

: tagaturonate reductase
Tagaturonate reductase
Tagaturonate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-altronate and NAD+, whereas its 3 products are D-tagaturonate, NADH, and H+....

: 3-hydroxypropionate dehydrogenase
3-hydroxypropionate dehydrogenase
In enzymology, a 3-hydroxypropionate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-hydroxypropanoate and NAD+, whereas its 3 products are 3-oxopropanoate, NADH, and H+....

: 2-hydroxy-3-oxopropionate reductase
2-hydroxy-3-oxopropionate reductase
In enzymology, a 2-hydroxy-3-oxopropionate reductase is an enzyme that catalyzes the chemical reaction-glycerate + NAD+ \rightleftharpoons 2-hydroxy-3-oxopropanoate + NADH + H+...

: 4-hydroxybutyrate dehydrogenase
4-hydroxybutyrate dehydrogenase
In enzymology, a 4-hydroxybutyrate dehydrogenase is an enzyme that catalyzes the chemical reactionThe two substrates of this enzyme are therefore 4-hydroxybutanoic acid, and NAD+, whereas its 3 products are succinate semialdehyde, NADH, and H+....

: estradiol 17b-dehydrogenase: testosterone 17b-dehydrogenase: testosterone 17b-dehydrogenase (NADP+): pyridoxine 4-dehydrogenase
Pyridoxine 4-dehydrogenase
In enzymology, a pyridoxine 4-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are pyridoxine and NADP+, whereas its 3 products are pyridoxal, NADPH, and H+....

: w-hydroxydecanoate dehydrogenase: mannitol 2-dehydrogenase
Mannitol 2-dehydrogenase
In enzymology, a mannitol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-mannitol and NAD+, whereas its 3 products are D-fructose, NADH, and H+....

: now *EC 1.7.99.5: gluconate 5-dehydrogenase
Gluconate 5-dehydrogenase
In enzymology, a gluconate 5-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-gluconate, NAD+, and NADP+, whereas its 4 products are 5-dehydro-D-gluconate, NADH, NADPH, and H+....

: deleted, included in *EC 1.2.1.3: alcohol dehydrogenase (NAD(P)+)
Alcohol dehydrogenase (NAD(P)+)
In enzymology, an alcohol dehydrogenase [NAD+] is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are alcohol, NAD+, and NADP+, whereas its 4 products are aldehyde, NADH, NADPH, and H+....

: glycerol dehydrogenase (NADP+)
Glycerol dehydrogenase (NADP+)
In enzymology, a glycerol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glycerol and NADP+, whereas its 3 products are D-glyceraldehyde, NADPH, and H+....

: octanol dehydrogenase
Octanol dehydrogenase
In enzymology, an octanol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1-octanol and NAD+, whereas its 3 products are 1-octanal, NADH, and H+....

: deleted: (R)-aminopropanol dehydrogenase
(R)-aminopropanol dehydrogenase
In enzymology, a -aminopropanol dehydrogenase is an enzyme that catalyzes the chemical reaction-1-aminopropan-2-ol + NAD+ \rightleftharpoons aminoacetone + NADH + H+...

: (S,S)-butanediol dehydrogenase
(S,S)-butanediol dehydrogenase
In enzymology, a -butanediol dehydrogenase is an enzyme that catalyzes the chemical reaction-butane-2,3-diol + NAD+ \rightleftharpoons acetoin + NADH + H+...

: lactaldehyde reductase
Lactaldehyde reductase
In enzymology, a lactaldehyde reductase is an enzyme that catalyzes the chemical reaction[or ]-propane-1,2-diol + NAD+ \rightleftharpoons [or ]-lactaldehyde + NADH + H+...

: methylglyoxal reductase (NADH-dependent)
Methylglyoxal reductase (NADH-dependent)
In enzymology, a methylglyoxal reductase is an enzyme that catalyzes the chemical reaction-lactaldehyde + NAD+ \rightleftharpoons methylglyoxal + NADH + H+...

: glyoxylate reductase (NADP+)
Glyoxylate reductase (NADP+)
In enzymology, a glyoxylate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glycolate and NADP+, whereas its 3 products are glyoxylate, NADPH, and H+....

: isopropanol dehydrogenase (NADP+)
Isopropanol dehydrogenase (NADP+)
In enzymology, an isopropanol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are propan-2-ol and NADP+, whereas its 3 products are acetone, NADPH, and H+....

: hydroxypyruvate reductase
Hydroxypyruvate reductase
In enzymology, a hydroxypyruvate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-glycerate, NAD+, and NADP+, whereas its 4 products are hydroxypyruvate, NADH, NADPH, and H+....

: malate dehydrogenase (NADP+)
Malate dehydrogenase (NADP+)
In enzymology, a malate dehydrogenase is an enzyme that catalyzes the chemical reaction-malate + NADP+ \rightleftharpoons oxaloacetate + NADPH + H+...

: D-malate dehydrogenase (decarboxylating)
D-malate dehydrogenase (decarboxylating)
In enzymology, a D-malate dehydrogenase is an enzyme that catalyzes the chemical reaction-malate + NAD+ \rightleftharpoons pyruvate + CO2 + NADH...

: dimethylmalate dehydrogenase
Dimethylmalate dehydrogenase
In enzymology, a dimethylmalate dehydrogenase is an enzyme that catalyzes the chemical reaction-3,3-dimethylmalate + NAD+ \rightleftharpoons 3-methyl-2-oxobutanoate + CO2 + NADH...

: 3-isopropylmalate dehydrogenase
3-Isopropylmalate dehydrogenase
3-Isopropylmalate dehydrogenase is an enzyme that catalyzes the following chemical reaction:* -3-isopropylmalate + NAD+ 4-methyl-2-oxopentanoate + CO2 + NADH...

: ketol-acid reductoisomerase
Ketol-acid reductoisomerase
In enzymology, a ketol-acid reductoisomerase is an enzyme that catalyzes the chemical reaction-2,3-dihydroxy-3-methylbutanoate + NADP+ \rightleftharpoons -2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+...

: homoisocitrate dehydrogenase
Homoisocitrate dehydrogenase
In enzymology, a homoisocitrate dehydrogenase is an enzyme that catalyzes the chemical reaction-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ \rightleftharpoons 2-oxoadipate + CO2 + NADH + H+...

: hydroxymethylglutaryl-CoA reductase: deleted, included in *EC 1.1.1.86: aryl-alcohol dehydrogenase
Aryl-alcohol dehydrogenase
In enzymology, an aryl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are aromatic alcohol and NAD+, whereas its 3 products are aromatic aldehyde, NADH, and H+....

: aryl-alcohol dehydrogenase (NADP+)
Aryl-alcohol dehydrogenase (NADP+)
In enzymology, an aryl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are aromatic alcohol and NADP+, whereas its 3 products are aromatic aldehyde, NADPH, and H+....

: oxaloglycolate reductase (decarboxylating)
Oxaloglycolate reductase (decarboxylating)
In enzymology, an oxaloglycolate reductase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are D-glycerate, NAD+, NADP+, and CO2, whereas its 4 products are 2-hydroxy-3-oxosuccinate, NADH, NADPH, and H+....

: tartrate dehydrogenase
Tartrate dehydrogenase
In enzymology, a tartrate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are tartrate and NAD+, whereas its 3 products are oxaloglycolate, NADH, and H+....

: glycerol-3-phosphate dehydrogenase (NAD(P)+)
Glycerol-3-phosphate dehydrogenase (NAD(P)+)
In enzymology, a glycerol-3-phosphate dehydrogenase [NAD+] is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are sn-glycerol 3-phosphate, NAD+, and NADP+, whereas its 4 products are glycerone phosphate, NADH, NADPH, and H+....

: phosphoglycerate dehydrogenase
Phosphoglycerate dehydrogenase
D-3-phosphoglycerate dehydrogenase is an enzyme that in humans is encoded by the PHGDH gene.Certain breast cancers are dependent on the overexpression of PHGDH.-Further reading:...

: diiodophenylpyruvate reductase
Diiodophenylpyruvate reductase
In enzymology, a diiodophenylpyruvate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-lactate and NAD+, whereas its 3 products are 3-pyruvate, NADH, and H+.This enzyme belongs to the family of oxidoreductases, specifically those acting on...

: 3-hydroxybenzyl-alcohol dehydrogenase
3-hydroxybenzyl-alcohol dehydrogenase
In enzymology, a 3-hydroxybenzyl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-hydroxybenzyl alcohol and NADP+, whereas its 3 products are 3-hydroxybenzaldehyde, NADPH, and H+....

: (R)-2-hydroxy-fatty-acid dehydrogenase
(R)-2-hydroxy-fatty-acid dehydrogenase
In enzymology, a -2-hydroxy-fatty-acid dehydrogenase is an enzyme that catalyzes the chemical reaction-2-hydroxystearate + NAD+ \rightleftharpoons 2-oxostearate + NADH + H+...

: (S)-2-hydroxy-fatty-acid dehydrogenase
(S)-2-hydroxy-fatty-acid dehydrogenase
In enzymology, a -2-hydroxy-fatty-acid dehydrogenase is an enzyme that catalyzes the chemical reaction-2-hydroxystearate + NAD+ \rightleftharpoons 2-oxostearate + NADH + H+...

: 3-oxoacyl-(acyl-carrier-protein) reductase
3-oxoacyl-(acyl-carrier-protein) reductase
In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase is an enzyme that catalyzes the chemical reaction-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ \rightleftharpoons 3-oxoacyl-[acyl-carrier-protein] + NADPH + H+...

: acylglycerone-phosphate reductase
Acylglycerone-phosphate reductase
In enzymology, an acylglycerone-phosphate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1-palmitoylglycerol 3-phosphate and NADP+, whereas its 3 products are palmitoylglycerone phosphate, NADPH, and H+.This enzyme belongs to the family of...

: 3-dehydrosphinganine reductase
3-dehydrosphinganine reductase
3-dehydrosphinganine reductase also known as 3-ketodihydrosphingosine reductase or follicular variant translocation protein 1 is an enzyme that in humans is encoded by the KDSR gene.- Function :...

: L-threonine 3-dehydrogenase
L-threonine 3-dehydrogenase
In enzymology, a L-threonine 3-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-threonine and NAD+, whereas its 3 products are L-2-amino-3-oxobutanoate, NADH, and H+....

: 4-oxoproline reductase
4-oxoproline reductase
In enzymology, a 4-oxoproline reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 4-hydroxy-L-proline and NAD+, whereas its 3 products are 4-oxoproline, NADH, and H+....

: retinol dehydrogenase
Retinol dehydrogenase
In enzymology, a retinol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are retinol and NAD+, whereas its 3 products are retinal, NADH, and H+....

: pantoate 4-dehydrogenase
Pantoate 4-dehydrogenase
In enzymology, a pantoate 4-dehydrogenase is an enzyme that catalyzes the chemical reaction-pantoate + NAD+ \rightleftharpoons -4-dehydropantoate + NADH + H+...

: pyridoxal 4-dehydrogenase
Pyridoxal 4-dehydrogenase
In enzymology, a pyridoxal 4-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are pyridoxal and NAD+, whereas its 3 products are 4-pyridoxolactone, NADH, and H+....

: carnitine 3-dehydrogenase
Carnitine 3-dehydrogenase
In enzymology, a carnitine 3-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are carnitine and NAD+, whereas its 3 products are 3-dehydrocarnitine, NADH, and H+....

: now *EC 1.3.1.28: indolelactate dehydrogenase
Indolelactate dehydrogenase
In enzymology, an indolelactate dehydrogenase is an enzyme that catalyzes the chemical reactionlactate + NAD+ \rightleftharpoons pyruvate + NADH + H+...

: 3-(imidazol-5-yl)lactate dehydrogenase
3-(imidazol-5-yl)lactate dehydrogenase
In enzymology, a 3-lactate dehydrogenase is an enzyme that catalyzes the chemical reaction-3-lactate + NAD+ \rightleftharpoons 3-pyruvate + NADH + H+...

: indanol dehydrogenase
Indanol dehydrogenase
In enzymology, an indanol dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are indan-1-ol, NAD+, and NADP+, whereas its 4 products are indanone, NADH, NADPH, and H+....

: L-xylose 1-dehydrogenase
L-xylose 1-dehydrogenase
In enzymology, a L-xylose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-xylose and NADP+, whereas its 3 products are L-xylono-1,4-lactone, NADPH, and H+....

: apiose 1-reductase
Apiose 1-reductase
In enzymology, an apiose 1-reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-apiitol and NAD+, whereas its 3 products are D-apiose, NADH, and H+....

: ribose 1-dehydrogenase (NADP+)
Ribose 1-dehydrogenase (NADP+)
In enzymology, a ribose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThe three substrates of this enzyme are D-ribose, NADP+, and H2O, whereas its 3 products are D-ribonate, NADPH, and H+....

: D-arabinose 1-dehydrogenase
D-arabinose 1-dehydrogenase
In enzymology, a D-arabinose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-arabinose and NAD+, whereas its 3 products are D-arabinono-1,4-lactone, NADH, and H+....

: D-arabinose 1-dehydrogenase (NAD(P)+)
D-arabinose 1-dehydrogenase (NAD(P)+)
In enzymology, a D-arabinose 1-dehydrogenase [NAD+] is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-arabinose, NAD+, and NADP+, whereas its 4 products are D-arabinono-1,4-lactone, NADH, NADPH, and H+....

: glucose 1-dehydrogenase (NAD+)
Glucose 1-dehydrogenase (NAD+)
In enzymology, a glucose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-glucose and NAD+, whereas its 3 products are D-glucono-1,5-lactone, NADH, and H+....

: glucose 1-dehydrogenase (NADP+)
Glucose 1-dehydrogenase (NADP+)
In enzymology, a glucose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-glucose and NADP+, whereas its 3 products are D-glucono-1,5-lactone, NADPH, and H+....

: galactose 1-dehydrogenase (NADP+)
Galactose 1-dehydrogenase (NADP+)
In enzymology, a galactose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-galactose and NADP+, whereas its 3 products are D-galactonolactone, NADPH, and H+....

: aldose 1-dehydrogenase
Aldose 1-dehydrogenase
In enzymology, an aldose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-aldose and NAD+, whereas its 3 products are D-aldonolactone, NADH, and H+....

: D-threo-aldose 1-dehydrogenase
D-threo-aldose 1-dehydrogenase
In enzymology, a D-threo-aldose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-threo-aldose and NAD+, whereas its 3 products are D-threo-aldono-1,5-lactone, NADH, and H+....

: sorbose 5-dehydrogenase (NADP+)
Sorbose 5-dehydrogenase (NADP+)
In enzymology, a sorbose 5-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-sorbose and NADP+, whereas its 3 products are 5-dehydro-D-fructose, NADPH, and H+....

: fructose 5-dehydrogenase (NADP+)
Fructose 5-dehydrogenase (NADP+)
In enzymology, a fructose 5-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-fructose and NADP+, whereas its 3 products are 5-dehydro-D-fructose, NADPH, and H+....

: 2-deoxy-D-gluconate 3-dehydrogenase
2-deoxy-D-gluconate 3-dehydrogenase
2-deoxy-D-gluconate 3-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-deoxy-D-gluconate and NAD+, whereas its 3 products are 3-dehydro-2-deoxy-D-gluconate, NADH, and H+....

: 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
In enzymology, a 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-dehydro-3-deoxy-D-gluconate and NADP+, whereas its 3 products are -4,5-dihydroxy-2,6-dioxohexanoate, NADPH, and H+.This enzyme belongs to...

: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
In enzymology, a 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-dehydro-3-deoxy-D-gluconate and NAD+, whereas its 3 products are -4,6-dihydroxy-2,5-dioxohexanoate, NADH, and H+.This enzyme belongs to the...

: L-idonate 2-dehydrogenase
L-idonate 2-dehydrogenase
In enzymology, a L-idonate 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-idonate and NADP+, whereas its 3 products are 5-dehydro-D-gluconate, NADPH, and H+....

: L-threonate 3-dehydrogenase
L-threonate 3-dehydrogenase
In enzymology, a L-threonate 3-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-threonate and NAD+, whereas its 3 products are 3-dehydro-L-threonate, NADH, and H+....

: 3-dehydro-L-gulonate 2-dehydrogenase
3-dehydro-L-gulonate 2-dehydrogenase
In enzymology, a 3-dehydro-L-gulonate 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 3-dehydro-L-gulonate, NAD+, and NADP+, whereas its 4 products are -4,5,6-trihydroxy-2,3-dioxohexanoate, NADH, NADPH, and H+.This enzyme belongs to the family...

: mannuronate reductase
Mannuronate reductase
In enzymology, a mannuronate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-mannonate, NAD+, and NADP+, whereas its 4 products are D-mannuronate, NADH, NADPH, and H+....

: GDP-mannose 6-dehydrogenase
GDP-mannose 6-dehydrogenase
In enzymology, a GDP-mannose 6-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are GDP-D-mannose, NAD+, and H2O, whereas its 3 products are GDP-D-mannuronate, NADH, and H+....

: dTDP-4-dehydrorhamnose reductase
DTDP-4-dehydrorhamnose reductase
In enzymology, a dTDP-4-dehydrorhamnose reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are dTDP-6-deoxy-L-mannose and NADP+, whereas its 3 products are dTDP-4-dehydro-6-deoxy-L-mannose, NADPH, and H+....

: dTDP-6-deoxy-L-talose 4-dehydrogenase
DTDP-6-deoxy-L-talose 4-dehydrogenase
In enzymology, a dTDP-6-deoxy-L-talose 4-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are dTDP-6-deoxy-L-talose and NADP+, whereas its 3 products are dTDP-4-dehydro-6-deoxy-L-mannose, NADPH, and H+....

: GDP-6-deoxy-D-talose 4-dehydrogenase
GDP-6-deoxy-D-talose 4-dehydrogenase
In enzymology, a GDP-6-deoxy-D-talose 4-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are GDP-6-deoxy-D-talose, NAD+, and NADP+, whereas its 4 products are GDP-4-dehydro-6-deoxy-D-mannose, NADH, NADPH, and H+....

: UDP-N-acetylglucosamine 6-dehydrogenase
UDP-N-acetylglucosamine 6-dehydrogenase
In enzymology, an UDP-N-acetylglucosamine 6-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are UDP-N-acetyl-D-glucosamine, NAD+, and H2O, whereas its 3 products are UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate, NADH, and H+.This enzyme belongs to the...

: ribitol-5-phosphate 2-dehydrogenase
Ribitol-5-phosphate 2-dehydrogenase
In enzymology, a ribitol-5-phosphate 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-ribitol 5-phosphate, NAD+, and NADP+, whereas its 4 products are D-ribulose 5-phosphate, NADH, NADPH, and H+....

: mannitol 2-dehydrogenase (NADP+)
Mannitol 2-dehydrogenase (NADP+)
In enzymology, a mannitol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-mannitol and NADP+, whereas its 3 products are D-fructose, NADPH, and H+....

: deleted, included in *EC 1.1.1.21: sorbitol-6-phosphate 2-dehydrogenase
Sorbitol-6-phosphate 2-dehydrogenase
In enzymology, a sorbitol-6-phosphate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-sorbitol 6-phosphate and NAD+, whereas its 3 products are D-fructose 6-phosphate, NADH, and H+....

: 15-hydroxyprostaglandin dehydrogenase (NAD+)
15-hydroxyprostaglandin dehydrogenase (NAD+)
In enzymology, a 15-hydroxyprostaglandin dehydrogenase is an enzyme that catalyzes the chemical reaction--11alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ \rightleftharpoons -11alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+...

: D-pinitol dehydrogenase
D-pinitol dehydrogenase
In enzymology, a D-pinitol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1D-3-O-methyl-chiro-inositol and NADP+, whereas its 3 products are 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone, NADPH, and H+.This enzyme belongs to the...

: sequoyitol dehydrogenase
Sequoyitol dehydrogenase
In enzymology, a sequoyitol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5-O-methyl-myo-inositol and NAD+, whereas its 3 products are 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone, NADH, and H+.This enzyme belongs to the family of...

: perillyl-alcohol dehydrogenase
Perillyl-alcohol dehydrogenase
In enzymology, a perillyl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are perillyl alcohol and NAD+, whereas its 3 products are perillyl aldehyde, NADH, and H+....

: 3b-hydroxy-D5-steroid dehydrogenase: 11b-hydroxysteroid dehydrogenase: 16a-hydroxysteroid dehydrogenase: estradiol 17a-dehydrogenase: 20a-hydroxysteroid dehydrogenase: 21-hydroxysteroid dehydrogenase (NAD+)
21-hydroxysteroid dehydrogenase (NAD+)
In enzymology, a 21-hydroxysteroid dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are pregnan-21-ol and NAD+, whereas its 3 products are pregnan-21-al, NADH, and H+....

: 21-hydroxysteroid dehydrogenase (NADP+)
21-hydroxysteroid dehydrogenase (NADP+)
In enzymology, a 21-hydroxysteroid dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are pregnan-21-ol and NADP+, whereas its 3 products are pregnan-21-al, NADPH, and H+....

: 3a-hydroxy-5b-androstane-17-one 3a-dehydrogenase: sepiapterin reductase
Sepiapterin reductase
In enzymology, a sepiapterin reductase is an enzyme that catalyzes the following chemical reaction:Thus, the two substrates of this enzyme are 7,8-dihydrobiopterin and NADP+, whereas its three products are tetrahydrobiopterin or sepiapterin, NADPH, and a single hydrogen ion .This enzyme belongs...

: ureidoglycolate dehydrogenase
Ureidoglycolate dehydrogenase
In enzymology, an ureidoglycolate dehydrogenase is an enzyme that catalyzes the chemical reaction-ureidoglycolate + NAD+ \rightleftharpoons oxalureate + NADH + H+...

: identical to *EC 1.1.1.87: glycerol 2-dehydrogenase (NADP+)
Glycerol 2-dehydrogenase (NADP+)
In enzymology, a glycerol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glycerol and NADP+, whereas its 3 products are glycerone, NADPH, and H+....

: 3-hydroxybutyryl-CoA dehydrogenase
3-hydroxybutyryl-CoA dehydrogenase
In enzymology, a 3-hydroxybutyryl-CoA dehydrogenase is an enzyme that catalyzes the chemical reaction-3-hydroxybutanoyl-CoA + NADP+ \rightleftharpoons 3-acetoacetyl-CoA + NADPH + H+...

: UDP-N-acetylmuramate dehydrogenase
UDP-N-acetylmuramate dehydrogenase
In enzymology, an UDP-N-acetylmuramate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are UDP-N-acetylmuramate and NADP+, whereas its 3 products are UDP-N-acetyl-3-O--D-glucosamine, NADPH, and H+.This enzyme belongs to the family of...

: 7a-hydroxysteroid dehydrogenase: dihydrobunolol dehydrogenase
Dihydrobunolol dehydrogenase
In enzymology, a dihydrobunolol dehydrogenase is an enzyme that catalyzes the chemical reaction-5-[-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1- naphthol + NADP+ \rightleftharpoons -5-[-2'-hydroxypropoxy]-3,4-dihydro-1- naphthalenone + NADPH + H+The three substrates of this enzyme are...

: cholestanetetraol 26-dehydrogenase
Cholestanetetraol 26-dehydrogenase
In enzymology, a cholestanetetraol 26-dehydrogenase is an enzyme that catalyzes the chemical reaction-5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol + NAD+ \rightleftharpoons -3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + NADH + H+...

: erythrulose reductase
Erythrulose reductase
In enzymology, an erythrulose reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are erythritol and NADP+, whereas its 3 products are D-erythrulose, NADPH, and H+....

: cyclopentanol dehydrogenase
Cyclopentanol dehydrogenase
In enzymology, a cyclopentanol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cyclopentanol and NAD+, whereas its 3 products are cyclopentanone, NADH, and H+....

: hexadecanol dehydrogenase
Hexadecanol dehydrogenase
In enzymology, a hexadecanol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are hexadecanol and NAD+, whereas its 3 products are hexadecanal, NADH, and H+....

: 2-alkyn-1-ol dehydrogenase
2-alkyn-1-ol dehydrogenase
In enzymology, a 2-alkyn-1-ol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-butyne-1,4-diol and NAD+, whereas its 3 products are 4-hydroxy-2-butynal, NADH, and H+....

: hydroxycyclohexanecarboxylate dehydrogenase
Hydroxycyclohexanecarboxylate dehydrogenase
In enzymology, a hydroxycyclohexanecarboxylate dehydrogenase is an enzyme that catalyzes the chemical reaction-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ \rightleftharpoons -4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H+...

: hydroxymalonate dehydrogenase
Hydroxymalonate dehydrogenase
In enzymology, a hydroxymalonate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are hydroxymalonate and NAD+, whereas its 3 products are oxomalonate, NADH, and H+....

: 2-dehydropantolactone reductase (A-specific)
2-dehydropantolactone reductase (A-specific)
In enzymology, a 2-dehydropantolactone reductase is an enzyme that catalyzes the chemical reaction-pantolactone + NADP+ \rightleftharpoons 2-dehydropantolactone + NADPH + H+...

: 2-dehydropantoate 2-reductase
2-dehydropantoate 2-reductase
In enzymology, a 2-dehydropantoate 2-reductase is an enzyme that catalyzes the chemical reaction-pantoate + NADP+ \rightleftharpoons 2-dehydropantoate + NADPH + H+...

: 3b-hydroxy-4a-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating): now *EC 1.5.1.20: 2-oxoadipate reductase
2-oxoadipate reductase
In enzymology, a 2-oxoadipate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-hydroxyadipate and NAD+, whereas its 3 products are 2-oxoadipate, NADH, and H+....

: L-rhamnose 1-dehydrogenase
L-rhamnose 1-dehydrogenase
In enzymology, a L-rhamnose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-rhamnofuranose and NAD+, whereas its 3 products are L-rhamno-1,4-lactone, NADH, and H+....

: cyclohexane-1,2-diol dehydrogenase
Cyclohexane-1,2-diol dehydrogenase
In enzymology, a cyclohexane-1,2-diol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are trans-cyclohexane-1,2-diol and NAD+, whereas its 3 products are 2-hydroxycyclohexan-1-one, NADH, and H+....

: D-xylose 1-dehydrogenase
D-xylose 1-dehydrogenase
In enzymology, a D-xylose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-xylose and NAD+, whereas its 3 products are D-xylonolactone, NADH, and H+....

: 12a-hydroxysteroid dehydrogenase: glycerol-3-phosphate 1-dehydrogenase (NADP+)
Glycerol-3-phosphate 1-dehydrogenase (NADP+)
In enzymology, a glycerol-3-phosphate 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are sn-glycerol 3-phosphate and NADP+, whereas its 3 products are D-glyceraldehyde 3-phosphate, NADPH, and H+.This enzyme belongs to the family of...

: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
3-hydroxy-2-methylbutyryl-CoA dehydrogenase
In enzymology, a 3-hydroxy-2-methylbutyryl-CoA dehydrogenase is an enzyme that catalyzes the chemical reaction-3-hydroxy-2-methylbutanoyl-CoA + NAD+ \rightleftharpoons 2-methylacetoacetyl-CoA + NADH + H+...

: D-xylose 1-dehydrogenase (NADP+)
D-xylose 1-dehydrogenase (NADP+)
In enzymology, a D-xylose 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-xylose and NADP+, whereas its 3 products are D-xylono-1,5-lactone, NADPH, and H+....

: deleted, included in *EC 1.1.1.131: cholest-5-ene-3b,7a-diol 3b-dehydrogenase: deleted, included in *EC 1.1.1.198, *EC 1.1.1.227 and *EC 1.1.1.228: geraniol dehydrogenase
Geraniol dehydrogenase
In enzymology, a geraniol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are geraniol and NADP+, whereas its 3 products are geranial, NADPH, and H+....

: carbonyl reductase (NADPH)
Carbonyl reductase (NADPH)
In enzymology, a carbonyl reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are R-CHOH-R' and NADP+, whereas its 3 products are R-CO-R', NADPH, and H+....

: L-glycol dehydrogenase
L-glycol dehydrogenase
In enzymology, a L-glycol dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-glycol, NAD+, and NADP+, whereas its 4 products are 2-hydroxycarbonyl compound, NADH, NADPH, and H+....

: dTDP-galactose 6-dehydrogenase
DTDP-galactose 6-dehydrogenase
In enzymology, a dTDP-galactose 6-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are dTDP-D-galactose, NADP+, and H2O, whereas its 3 products are dTDP-D-galacturonate, NADPH, and H+....

: GDP-4-dehydro-D-rhamnose reductase
GDP-4-dehydro-D-rhamnose reductase
In enzymology, a GDP-4-dehydro-D-rhamnose reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are GDP-6-deoxy-D-mannose, NAD+, and NADP+, whereas its 4 products are GDP-4-dehydro-6-deoxy-D-mannose, NADH, NADPH, and H+....

: prostaglandin-F synthase
Prostaglandin-F synthase
In enzymology, a prostaglandin-F synthase is an enzyme that catalyzes the chemical reaction--9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ \rightleftharpoons --9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate + NADPH + H+...

: prostaglandin-E2 9-reductase
Prostaglandin-E2 9-reductase
In enzymology, a prostaglandin-E2 9-reductase is an enzyme that catalyzes the chemical reaction--9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ \rightleftharpoons --11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH + H+...

: indole-3-acetaldehyde reductase (NADH)
Indole-3-acetaldehyde reductase (NADH)
In enzymology, an indole-3-acetaldehyde reductase is an enzyme that catalyzes the chemical reactionethanol + NAD+ \rightleftharpoons acetaldehyde + NADH + H+...

: indole-3-acetaldehyde reductase (NADPH)
Indole-3-acetaldehyde reductase (NADPH)
In enzymology, an indole-3-acetaldehyde reductase is an enzyme that catalyzes the chemical reactionethanol + NADP+ \rightleftharpoons acetaldehyde + NADPH + H+...

: long-chain-alcohol dehydrogenase
Long-chain-alcohol dehydrogenase
In enzymology, a long-chain-alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are long-chain alcohol, NAD+, and H2O, whereas its 3 products are long-chain carboxylate, NADH, and H+....

: 5-amino-6-(5-phosphoribosylamino)uracil reductase
5-amino-6-(5-phosphoribosylamino)uracil reductase
In enzymology, a 5-amino-6-uracil reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5-amino-6-uracil and NADP+, whereas its 3 products are 5-amino-6-uracil, NADPH, and H+.This enzyme belongs to the family of oxidoreductases, specifically those...

: coniferyl-alcohol dehydrogenase
Coniferyl-alcohol dehydrogenase
In enzymology, a coniferyl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are coniferyl alcohol and NADP+, whereas its 3 products are coniferyl aldehyde, NADPH, and H+....

: cinnamyl-alcohol dehydrogenase
Cinnamyl-alcohol dehydrogenase
In enzymology, a cinnamyl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cinnamyl alcohol and NADP+, whereas its 3 products are cinnamaldehyde, NADPH, and H+....

: 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
15-hydroxyprostaglandin-D dehydrogenase (NADP+)
In enzymology, a 15-hydroxyprostaglandin-D dehydrogenase is an enzyme that catalyzes the chemical reaction--9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate + NADP+ \rightleftharpoons -9alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate + NADPH + H+Thus, the two substrates of this enzyme are...

: 15-hydroxyprostaglandin dehydrogenase (NADP+)
15-hydroxyprostaglandin dehydrogenase (NADP+)
In enzymology, a 15-hydroxyprostaglandin dehydrogenase is an enzyme that catalyzes the chemical reaction--11alpha,15-dihydroxy-9-oxoprost-13-enoate + NADP+ \rightleftharpoons -11alpha-hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+...

: (+)-borneol dehydrogenase
(+)-borneol dehydrogenase
In enzymology, a -borneol dehydrogenase is an enzyme that catalyzes the chemical reaction-borneol + NAD+ \rightleftharpoons -camphor + NADH + H+...

: (S)-usnate reductase
(S)-usnate reductase
In enzymology, a -usnate reductase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is reduced--usnate:NAD+...

: aldose-6-phosphate reductase (NADPH)
Aldose-6-phosphate reductase (NADPH)
In enzymology, an aldose-6-phosphate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-sorbitol 6-phosphate and NADP+, whereas its 3 products are D-glucose 6-phosphate, NADPH, and H+....

: 7b-hydroxysteroid dehydrogenase (NADP+): 1,3-propanediol dehydrogenase
1,3-propanediol dehydrogenase
In enzymology, a 1,3-propanediol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are propane-1,3-diol and NAD+, whereas its 3 products are 3-hydroxypropanal, NADH, and H+....

: uronate dehydrogenase
Uronate dehydrogenase
In enzymology, an uronate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-galacturonate, NAD+, and H2O, whereas its 3 products are D-galactarate, NADH, and H+....

: now *EC 1.17.1.4: IMP dehydrogenase
IMP dehydrogenase
IMP dehydrogenase is an enzyme that converts inosine monophosphate to xanthosine monophosphate:The structure of this enzyme is composed of a TIM barrel domain with two CBS domains inserted within a loop.It is inhibited by Mycophenolic acid.- Examples :...

: tropine dehydrogenase: (-)-menthol dehydrogenase
(-)-menthol dehydrogenase
In enzymology, a -menthol dehydrogenase is an enzyme that catalyzes the chemical reaction-menthol + NADP+ \rightleftharpoons -menthone + NADPH + H+...

: (+)-neomenthol dehydrogenase
(+)-neomenthol dehydrogenase
In enzymology, a -neomenthol dehydrogenase is an enzyme that catalyzes the chemical reaction-neomenthol + NADP+ \rightleftharpoons -menthone + NADPH + H+...

: 3(or 17)a-hydroxysteroid dehydrogenase: 3b(or 20a)-hydroxysteroid dehydrogenase: long-chain-3-hydroxyacyl-CoA dehydrogenase: 3-oxoacyl-(acyl-carrier-protein) reductase (NADH)
3-oxoacyl-(acyl-carrier-protein) reductase (NADH)
In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase is an enzyme that catalyzes the chemical reaction-3-hydroxyacyl-[acyl-carrier-protein] + NAD+ \rightleftharpoons 3-oxoacyl-[acyl-carrier-protein] + NADH + H+...

: 3a-hydroxysteroid dehydrogenase (A-specific): 2-dehydropantolactone reductase (B-specific)
2-dehydropantolactone reductase (B-specific)
In enzymology, a 2-dehydropantolactone reductase is an enzyme that catalyzes the chemical reaction-pantolactone + NADP+ \rightleftharpoons 2-dehydropantolactone + NADPH + H+...

: gluconate 2-dehydrogenase
Gluconate 2-dehydrogenase
In enzymology, a gluconate 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-gluconate and NADP+, whereas its 3 products are 2-dehydro-D-gluconate, NADPH, and H+....

: farnesol dehydrogenase
Farnesol dehydrogenase
In enzymology, a farnesol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-trans,6-trans-farnesol and NADP+, whereas its 3 products are 2-trans,6-trans-farnesal, NADPH, and H+....

: benzyl-2-methyl-hydroxybutyrate dehydrogenase
Benzyl-2-methyl-hydroxybutyrate dehydrogenase
In enzymology, a benzyl-2-methyl-hydroxybutyrate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are benzyl -2-methyl-3-hydroxybutanoate and NADP+, whereas its 3 products are benzyl 2-methyl-3-oxobutanoate, NADPH, and H+.This enzyme belongs to...

: morphine 6-dehydrogenase
Morphine 6-dehydrogenase
In enzymology, a morphine 6-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are morphine, NAD+, and NADP+, whereas its 4 products are morphinone, NADH, NADPH, and H+....

: dihydrokaempferol 4-reductase
Dihydrokaempferol 4-reductase
In enzymology, a dihydrokaempferol 4-reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-3,4-leucopelargonidin and NADP+, whereas its 3 products are -dihydrokaempferol, NADPH, and H+....

: 6-pyruvoyltetrahydropterin 2'-reductase
6-pyruvoyltetrahydropterin 2'-reductase
In enzymology, a 6-pyruvoyltetrahydropterin 2'-reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 6-lactoyl-5,6,7,8-tetrahydropterin and NADP+, whereas its 3 products are 6-pyruvoyltetrahydropterin, NADPH, and H+.This enzyme belongs to the family...

: vomifoliol 4'-dehydrogenase: (R)-4-hydroxyphenyllactate dehydrogenase
(R)-4-hydroxyphenyllactate dehydrogenase
In enzymology, a -4-hydroxyphenyllactate dehydrogenase is an enzyme that catalyzes the chemical reaction-3-lactate + NAD+ \rightleftharpoons 3-pyruvate + NADH + H+...

: isopiperitenol dehydrogenase
Isopiperitenol dehydrogenase
In enzymology, an isopiperitenol dehydrogenase is an enzyme that catalyzes the chemical reaction-trans-isopiperitenol + NAD+ \rightleftharpoons -isopiperitenone + NADH + H+...

: mannose-6-phosphate 6-reductase
Mannose-6-phosphate 6-reductase
In enzymology, a mannose-6-phosphate 6-reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-mannitol 1-phosphate and NADP+, whereas its 3 products are D-mannose 6-phosphate, NADPH, and H+....

: chlordecone reductase
Chlordecone reductase
In enzymology, a chlordecone reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are chlordecone alcohol and NADP+, whereas its 3 products are chlordecone, NADPH, and H+....

: 4-hydroxycyclohexanecarboxylate dehydrogenase
4-hydroxycyclohexanecarboxylate dehydrogenase
In enzymology, a 4-hydroxycyclohexanecarboxylate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are trans-4-hydroxycyclohexanecarboxylate and NAD+, whereas its 3 products are 4-oxocyclohexanecarboxylate, NADH, and H+.This enzyme belongs to...

: (-)-borneol dehydrogenase
(-)-borneol dehydrogenase
In enzymology, a -borneol dehydrogenase is an enzyme that catalyzes the chemical reaction-borneol + NAD+ \rightleftharpoons -camphor + NADH + H+...

: (+)-sabinol dehydrogenase
(+)-sabinol dehydrogenase
In enzymology, a -sabinol dehydrogenase is an enzyme that catalyzes the chemical reaction-cis-sabinol + NAD+ \rightleftharpoons -sabinone + NADH + H+...

: diethyl 2-methyl-3-oxosuccinate reductase
Diethyl 2-methyl-3-oxosuccinate reductase
In enzymology, a diethyl 2-methyl-3-oxosuccinate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are diethyl -2-methyl-3-hydroxysuccinate and NADP+, whereas its 3 products are diethyl 2-methyl-3-oxosuccinate, NADPH, and H+.This enzyme belongs to...

: 3a-hydroxyglycyrrhetinate dehydrogenase: 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
15-hydroxyprostaglandin-I dehydrogenase (NADP+)
In enzymology, a 15-hydroxyprostaglandin-I dehydrogenase is an enzyme that catalyzes the chemical reaction--6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13- dienoate + NADP+ \rightleftharpoons -6,9alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate + NADPH + H+The 3 substrates of this enzyme...

: 15-hydroxyicosatetraenoate dehydrogenase
15-hydroxyicosatetraenoate dehydrogenase
In enzymology, a 15-hydroxyicosatetraenoate dehydrogenase is an enzyme that catalyzes the chemical reaction-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate + NAD+ \rightleftharpoons 15-oxo-5,8,11-cis-13-trans-icosatetraenoate + NADH + H+...

: N-acylmannosamine 1-dehydrogenase
N-acylmannosamine 1-dehydrogenase
In enzymology, a N-acylmannosamine 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are N-acyl-D-mannosamine and NAD+, whereas its 3 products are N-acyl-D-mannosaminolactone, NADH, and H+....

: flavanone 4-reductase
Flavanone 4-reductase
In enzymology, a flavanone 4-reductase is an enzyme that catalyzes the chemical reaction-flavan-4-ol + NADP+ \rightleftharpoons -flavanone + NADPH + H+...

: 8-oxocoformycin reductase
8-oxocoformycin reductase
In enzymology, a 8-oxocoformycin reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are coformycin and NADP+, whereas its 3 products are 8-oxocoformycin, NADPH, and H+....

: tropinone reductase: hydroxyphenylpyruvate reductase
Hydroxyphenylpyruvate reductase
In enzymology, a hydroxyphenylpyruvate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-lactate and NAD+, whereas its 3 products are 3-pyruvate, NADH, and H+....

: 12b-hydroxysteroid dehydrogenase: 3a(17b)-hydroxysteroid dehydrogenase (NAD+): N-acetylhexosamine 1-dehydrogenase
N-acetylhexosamine 1-dehydrogenase
In enzymology, a N-acetylhexosamine 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are N-acetyl-D-glucosamine and NAD+, whereas its 3 products are N-acetyl-D-glucosaminate, NADH, and H+....

: 6-endo-hydroxycineole dehydrogenase
6-endo-hydroxycineole dehydrogenase
In enzymology, a 6-endo-hydroxycineole dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 6-endo-hydroxycineole and NAD+, whereas its 3 products are 6-oxocineole, NADH, and H+....

: zeatin reductase — now *EC 1.3.1.69: carveol dehydrogenase
Carveol dehydrogenase
In enzymology, a carveol dehydrogenase is an enzyme that catalyzes the chemical reaction-trans-carveol + NADP+ \rightleftharpoons -carvone + NADPH + H+...

: methanol dehydrogenase
Methanol dehydrogenase
In enzymology, a methanol dehydrogenase is an enzyme that catalyses the chemical reaction:How the electrons are captured and transported depends upon the kind of methanol dehydrogenase and there are two main types...

: cyclohexanol dehydrogenase
Cyclohexanol dehydrogenase
In enzymology, a cyclohexanol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cyclohexanol and NAD+, whereas its 3 products are cyclohexanone, NADH, and H+....

: pterocarpin synthase
Pterocarpin synthase
In enzymology, a pterocarpin synthase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are medicarpin, NADP+, and H2O, whereas its 3 products are vestitone, NADPH, and H+....

: codeinone reductase (NADPH)
Codeinone reductase (NADPH)
In enzymology, a codeinone reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are codeine and NADP+, whereas its 3 products are codeinone, NADPH, and H+....

: salutaridine reductase (NADPH)
Salutaridine reductase (NADPH)
In enzymology, a salutaridine reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are salutaridinol and NADP+, whereas its 3 products are salutaridine, NADPH, and H+....

: reinstated as *EC 2.5.1.46: D-arabinitol 2-dehydrogenase
D-arabinitol 2-dehydrogenase
In enzymology, a D-arabinitol 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-arabinitol and NAD+, whereas its 3 products are D-ribulose, NADH, and H+....

: galactitol-1-phosphate 5-dehydrogenase
Galactitol-1-phosphate 5-dehydrogenase
In enzymology, a galactitol-1-phosphate 5-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are galactitol-1-phosphate and NAD+, whereas its 3 products are L-tagatose 6-phosphate, NADH, and H+....

: tetrahydroxynaphthalene reductase
Tetrahydroxynaphthalene reductase
In enzymology, a tetrahydroxynaphthalene reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are scytalone and NADP+, whereas its 3 products are 1,3,6,8-tetrahydroxynaphthalene, NADPH, and H+....

: now *EC 1.5.1.33: (S)-carnitine 3-dehydrogenase
(S)-carnitine 3-dehydrogenase
In enzymology, a -carnitine 3-dehydrogenase is an enzyme that catalyzes the chemical reaction-carnitine + NAD+ \rightleftharpoons 3-dehydrocarnitine + NADH + H+...

: mannitol dehydrogenase
Mannitol dehydrogenase
In enzymology, a mannitol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-mannitol and NAD+, whereas its 3 products are D-mannose, NADH, and H+....

: fluoren-9-ol dehydrogenase
Fluoren-9-ol dehydrogenase
In enzymology, a fluoren-9-ol dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are fluoren-9-ol, NAD+, and NADP+, whereas its 4 products are fluoren-9-one, NADH, NADPH, and H+....

: 4-(hydroxymethyl)benzenesulfonate dehydrogenase
4-(hydroxymethyl)benzenesulfonate dehydrogenase
In enzymology, a 4-benzenesulfonate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 4-benzenesulfonate and NAD+, whereas its 3 products are 4-formylbenzenesulfonate, NADH, and H+.This enzyme belongs to the family of oxidoreductases,...

: 6-hydroxyhexanoate dehydrogenase
6-hydroxyhexanoate dehydrogenase
In enzymology, a 6-hydroxyhexanoate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 6-hydroxyhexanoate and NAD+, whereas its 3 products are 6-oxohexanoate, NADH, and H+....

: 3-hydroxypimeloyl-CoA dehydrogenase
3-hydroxypimeloyl-CoA dehydrogenase
In enzymology, a 3-hydroxypimeloyl-CoA dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-hydroxypimeloyl-CoA and NAD+, whereas its 3 products are 3-oxopimeloyl-CoA, NADH, and H+....

: sulcatone reductase
Sulcatone reductase
In enzymology, a sulcatone reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are sulcatol and NAD+, whereas its 3 products are sulcatone, NADH, and H+....

: glycerol-1-phosphate dehydrogenase (NAD(P)+)
Glycerol-1-phosphate dehydrogenase (NAD(P)+)
In enzymology, a glycerol-1-phosphate dehydrogenase [NAD+] is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are sn-glycerol-1-phosphate, NAD+, and NADP+, whereas its 4 products are glycerone phosphate, NADH, NADPH, and H+....

: 4-hydroxythreonine-4-phosphate dehydrogenase
4-hydroxythreonine-4-phosphate dehydrogenase
In enzymology, a 4-hydroxythreonine-4-phosphate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 4-phosphonooxy-L-threonine and NAD+, whereas its 3 products are -2-amino-3-oxo-4-phosphonooxybutanoate, NADH, and H+.This enzyme belongs to the...

: 1,5-anhydro-D-fructose reductase
1,5-anhydro-D-fructose reductase
In enzymology, a 1,5-anhydro-D-fructose reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1,5-anhydro-D-glucitol and NADP+, whereas its 3 products are 1,5-anhydro-D-fructose, NADPH, and H+....

: L-idonate 5-dehydrogenase
L-idonate 5-dehydrogenase
In enzymology, a L-idonate 5-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-idonate, NAD+, and NADP+, whereas its 4 products are 5-dehydrogluconate, NADH, NADPH, and H+....

: 3-methylbutanal reductase
3-methylbutanal reductase
In enzymology, a 3-methylbutanal reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 3-methylbutanol, NAD+, and NADP+, whereas its 4 products are 3-methylbutanal, NADH, NADPH, and H+....

: dTDP-4-dehydro-6-deoxyglucose reductase
DTDP-4-dehydro-6-deoxyglucose reductase
In enzymology, a dTDP-4-dehydro-6-deoxyglucose reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are dTDP-D-fucose and NADP+, whereas its 3 products are dTDP-4-dehydro-6-deoxy-D-glucose, NADPH, and H+....

: 1-deoxy-D-xylulose-5-phosphate reductoisomerase: 2-(R)-hydroxypropyl-CoM dehydrogenase
2-(R)-hydroxypropyl-CoM dehydrogenase
In enzymology, a 2--hydroxypropyl-CoM dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2--hydroxypropyl-CoM and NAD+, whereas its 3 products are 2-oxopropyl-CoM, NADH, and H+....

: 2-(S)-hydroxypropyl-CoM dehydrogenase
2-(S)-hydroxypropyl-CoM dehydrogenase
In enzymology, a 2--hydroxypropyl-CoM dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2--hydroxypropyl-CoM and NAD+, whereas its 3 products are 2-oxopropyl-CoM, NADH, and H+....

: 3-keto-steroid reductase
3-keto-steroid reductase
In enzymology, a 3-keto-steroid reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 4alpha-methyl-5alpha-cholest-7-en-3beta-ol and NADP+, whereas its 3 products are 4alpha-methyl-5alpha-cholest-7-en-3-one, NADPH, and H+.This enzyme belongs to the...

: GDP-L-fucose synthase
GDP-L-fucose synthase
In enzymology, a GDP-L-fucose synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are GDP-L-fucose and NADP+, whereas its 3 products are GDP-4-dehydro-6-deoxy-D-mannose, NADPH, and H+....

: (R)-2-hydroxyacid dehydrogenase
(R)-2-hydroxyacid dehydrogenase
In enzymology, a -2-hydroxyacid dehydrogenase is an enzyme that catalyzes the chemical reaction-3-sulfolactate + NAD+ \rightleftharpoons 3-sulfopyruvate + NADH + H+...

: vellosimine dehydrogenase
Vellosimine dehydrogenase
In enzymology, a vellosimine dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 10-deoxysarpagine and NADP+, whereas its 3 products are vellosimine, NADPH, and H+....

: 2,5-didehydrogluconate reductase
2,5-didehydrogluconate reductase
In enzymology, a 2,5-didehydrogluconate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-dehydro-D-gluconate and NADP+, whereas its 3 products are 2,5-didehydro-D-gluconate, NADPH, and H+....

: (+)-trans-carveol dehydrogenase
(+)-trans-carveol dehydrogenase
In enzymology, a -trans-carveol dehydrogenase is an enzyme that catalyzes the chemical reaction-trans-carveol + NAD+ \rightleftharpoons --carvone + NADH + H+...

: serine 3-dehydrogenase
Serine 3-dehydrogenase
In enzymology, a serine 3-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-serine and NADP+, whereas its 3 products are 2-ammoniomalonate semialdehyde, NADPH, and H+....

: 3b-hydroxy-5b-steroid dehydrogenase: 3b-hydroxy-5a-steroid dehydrogenase: (R)-3-hydroxyacid ester dehydrogenase: (S)-3-hydroxyacid ester dehydrogenase: GDP-4-dehydro-6-deoxy-D-mannose reductase
GDP-4-dehydro-6-deoxy-D-mannose reductase
In enzymology, a GDP-4-dehydro-6-deoxy-D-mannose reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are GDP-6-deoxy-D-mannose, NAD+, and NADP+, whereas its 4 products are GDP-4-dehydro-6-deoxy-D-mannose, NADH, NADPH, and H+.This enzyme belongs to the family...

: quinate/shikimate dehydrogenase: methylglyoxal reductase (NADPH-dependent)
Methylglyoxal reductase (NADPH-dependent)
In enzymology, a methylglyoxal reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are lactaldehyde and NADP+, whereas its 3 products are methylglyoxal, NADPH, and H+....

: S-(hydroxymethyl)glutathione dehydrogenase
S-(hydroxymethyl)glutathione dehydrogenase
In enzymology, a S-glutathione dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are S-glutathione, NAD+, and NADP+, whereas its 4 products are S-formylglutathione, NADH, NADPH, and H+.This enzyme belongs to the family of oxidoreductases, specifically...

: 3"-deamino-3"-oxonicotianamine reductase: isocitrate—homoisocitrate dehydrogenase
Isocitrate—homoisocitrate dehydrogenase
Isocitrate—homoisocitrate dehydrogenase is an enzyme that catalyzes the following two reactions:* isocitrate + NAD+ \rightleftharpoons 2-oxoglutarate + CO2 + NADH* homoisocitrate + NAD+ \rightleftharpoons 2-oxoadipate + CO2 + NADH + H+...

: D-arabinitol dehydrogenase (NADP+)

EC 1.1.2 With a cytochrome as acceptor

: now *EC 1.1.99.5: mannitol dehydrogenase (cytochrome)
Mannitol dehydrogenase (cytochrome)
In enzymology, a mannitol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-mannitol and ferricytochrome c, whereas its two products are D-fructose and ferrocytochrome c....

: L-lactate dehydrogenase (cytochrome)
L-lactate dehydrogenase (cytochrome)
In enzymology, a L-lactate dehydrogenase is an enzyme that catalyzes the chemical reaction-lactate + 2 ferricytochrome c \rightleftharpoons pyruvate + 2 ferrocytochrome c...

: D-lactate dehydrogenase (cytochrome)
D-lactate dehydrogenase (cytochrome)
In enzymology, a D-lactate dehydrogenase is an enzyme that catalyzes the chemical reaction-lactate + 2 ferricytochrome c \rightleftharpoons pyruvate + 2 ferrocytochrome c...

: D-lactate dehydrogenase (cytochrome c-553)
D-lactate dehydrogenase (cytochrome c-553)
In enzymology, a D-lactate dehydrogenase is an enzyme that catalyzes the chemical reaction-lactate + 2 ferricytochrome c-553 \rightleftharpoons pyruvate + 2 ferrocytochrome c-553...


EC 1.1.3 With oxygen as acceptor

: deleted, included in *EC 1.1.3.15: now *EC 1.13.12.4: malate oxidase
Malate oxidase
In enzymology, a malate oxidase is an enzyme that catalyzes the chemical reaction-malate + O2 \rightleftharpoons oxaloacetate + H2O2Thus, the two substrates of this enzyme are -malate and O2, whereas its two products are oxaloacetate and H2O2....

: glucose oxidase
Glucose oxidase
The glucose oxidase enzyme is an oxido-reductase that catalyses the oxidation of glucose to hydrogen peroxide and D-glucono-δ-lactone. In cells, it aids in breaking the sugar down into its metabolites....

: hexose oxidase
Hexose oxidase
In enzymology, a hexose oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-glucose and O2, whereas its two products are D-glucono-1,5-lactone and H2O2....

: cholesterol oxidase
Cholesterol oxidase
In enzymology, a cholesterol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cholesterol and O2, whereas its two products are cholest-4-en-3-one and H2O2....

: aryl-alcohol oxidase
Aryl-alcohol oxidase
In enzymology, an aryl-alcohol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are aromatic primary alcohol and O2, whereas its two products are aromatic aldehyde and H2O2....

: L-gulonolactone oxidase
L-gulonolactone oxidase
L-gulonolactone oxidase is an enzyme that catalyzes the reaction of D-glucuronolactone with oxygen to L-xylo-hex-3-gulonolactone and hydrogen peroxide. It uses FAD as a cofactor...

: galactose oxidase
Galactose oxidase
In enzymology, a galactose oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-galactose and O2, whereas its two products are D-galacto-hexodialdose and H2O2....

: pyranose oxidase
Pyranose oxidase
In enzymology, a pyranose oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-glucose and O2, whereas its two products are 2-dehydro-D-glucose and H2O2....

: L-sorbose oxidase
L-sorbose oxidase
In enzymology, a L-sorbose oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-sorbose and O2, whereas its two products are 5-dehydro-D-fructose and H2O2....

: pyridoxine 4-oxidase
Pyridoxine 4-oxidase
In enzymology, a pyridoxine 4-oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are pyridoxine and O2, whereas its two products are pyridoxal and H2O2....

: alcohol oxidase
Alcohol oxidase
In enzymology, an alcohol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are primary alcohol and O2, whereas its two products are aldehyde and H2O2....

: catechol oxidase (dimerizing)
Catechol oxidase (dimerizing)
In enzymology, a catechol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are catechol and O2, whereas its two products are dibenzo[1,4]dioxin-2,3-dione and H2O....

: (S)-2-hydroxy-acid oxidase
(S)-2-hydroxy-acid oxidase
In enzymology, a -2-hydroxy-acid oxidase is an enzyme that catalyzes the chemical reaction-2-hydroxy acid + O2 \rightleftharpoons 2-oxo acid + H2O2...

: ecdysone oxidase
Ecdysone oxidase
In enzymology, an ecdysone oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are ecdysone and O2, whereas its two products are 3-dehydroecdysone and H2O2....

: choline oxidase
Choline oxidase
In enzymology, a choline oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are choline and O2, whereas its two products are betaine aldehyde and H2O2....

: Secondary-alcohol oxidase
Secondary-alcohol oxidase
In enzymology, a secondary-alcohol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are secondary alcohol and O2, whereas its two products are ketone and H2O2....

: 4-hydroxymandelate oxidase
4-hydroxymandelate oxidase
In enzymology, a 4-hydroxymandelate oxidase is an enzyme that catalyzes the chemical reaction-2-hydroxy-2-acetate + O2 \rightleftharpoons 4-hydroxybenzaldehyde + CO2 + H2O2...

: long-chain-alcohol oxidase
Long-chain-alcohol oxidase
In enzymology, a long-chain-alcohol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are long-chain alcohol and O2, whereas its two products are long-chain aldehyde and H2O....

: glycerol-3-phosphate oxidase
Glycerol-3-phosphate oxidase
In enzymology, a glycerol-3-phosphate oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are sn-glycerol 3-phosphate and O2, whereas its two products are glycerone phosphate and H2O2....

: now *EC 1.17.3.2: Thiamine oxidase
Thiamine oxidase
In enzymology, a thiamine oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are thiamine, O2, and H2O, whereas its two products are thiamine acetic acid and H2O2....

: L-galactonolactone oxidase
L-galactonolactone oxidase
In enzymology, a L-galactonolactone oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-galactono-1,4-lactone and O2, whereas its two products are L-ascorbic acid and H2O2....

: now included with *EC 1.1.99.18: now *EC 1.21.3.2: hydroxyphytanate oxidase
Hydroxyphytanate oxidase
In enzymology, a hydroxyphytanate oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-2-hydroxyphytanate and O2, whereas its two products are 2-oxophytanate and H2O2....

: nucleoside oxidase: N-acylhexosamine oxidase
N-acylhexosamine oxidase
In enzymology, a N-acylhexosamine oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are N-acetyl-D-glucosamine and O2, whereas its two products are N-acetyl-D-glucosaminate and H2O2....

: polyvinyl-alcohol oxidase
Polyvinyl-alcohol oxidase
In enzymology, a polyvinyl-alcohol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are polyvinyl alcohol and O2, whereas its two products are oxidized polyvinyl alcohol and H2O2....

: deleted: now *EC 1.14.21.1: now *EC 1.14.21.2: now *EC 1.14.21.3: now *EC 1.14.21.4: now *EC 1.14.21.5: D-arabinono-1,4-lactone oxidase
D-arabinono-1,4-lactone oxidase
In enzymology, a D-arabinono-1,4-lactone oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-arabinono-1,4-lactone and O2, whereas its two products are D-erythro-ascorbate and H2O2....

: vanillyl-alcohol oxidase
Vanillyl-alcohol oxidase
In enzymology, a vanillyl-alcohol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are vanillyl alcohol and O2, whereas its two products are vanillin and H2O2....

: nucleoside oxidase (H2O2-forming): D-mannitol oxidase
D-mannitol oxidase
In enzymology, a D-mannitol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are mannitol and O2, whereas its two products are mannose and H2O2....

: xylitol oxidase
Xylitol oxidase
In enzymology, a xylitol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are xylitol and O2, whereas its two products are xylose and H2O2....


EC 1.1.4 With a disulfide as acceptor

: vitamin-K-epoxide reductase (warfarin-sensitive)
Vitamin-K-epoxide reductase (warfarin-sensitive)
In enzymology, a vitamin-K-epoxide reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-methyl-3-phytyl-1,4-naphthoquinone and oxidized dithiothreitol, whereas its two products are 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone and...

: vitamin-K-epoxide reductase (warfarin-insensitive)
Vitamin-K-epoxide reductase (warfarin-insensitive)
In enzymology, a vitamin-K-epoxide reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone and oxidized dithiothreitol, whereas its two products are...


EC 1.1.5 With a quinone or similar compound as acceptor

: deleted, see EC 1.1.99.18 cellobiose dehydrogenase (acceptor): quinoprotein glucose dehydrogenase
Quinoprotein glucose dehydrogenase
In enzymology, a quinoprotein glucose dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-glucose and ubiquinone, whereas its two products are D-glucono-1,5-lactone and ubiquinol....


EC 1.1.99 With other acceptors

: choline dehydrogenase
Choline dehydrogenase
In enzymology, a choline dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are choline and acceptor, whereas its two products are betaine aldehyde and reduced acceptor....

: 2-hydroxyglutarate dehydrogenase
2-hydroxyglutarate dehydrogenase
In enzymology, a 2-hydroxyglutarate dehydrogenase is an enzyme that catalyzes the chemical reaction-2-hydroxyglutarate + acceptor \rightleftharpoons 2-oxoglutarate + reduced acceptor...

: gluconate 2-dehydrogenase (acceptor)
Gluconate 2-dehydrogenase (acceptor)
In enzymology, a gluconate 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-gluconate and acceptor, whereas its two products are 2-dehydro-D-gluconate and reduced acceptor....

: dehydrogluconate dehydrogenase
Dehydrogluconate dehydrogenase
In enzymology, a dehydrogluconate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-dehydro-D-gluconate and acceptor, whereas its two products are 2,5-didehydro-D-gluconate and reduced acceptor....

: glycerol-3-phosphate dehydrogenase
Glycerol-3-phosphate dehydrogenase
Glycerol-3-phosphate dehydrogenase is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate to sn-glycerol 3-phosphate....

: D-2-hydroxy-acid dehydrogenase
D-2-hydroxy-acid dehydrogenase
In enzymology, a D-2-hydroxy-acid dehydrogenase is an enzyme that catalyzes the chemical reaction-lactate + acceptor \rightleftharpoons pyruvate + reduced acceptor...

: lactate—malate transhydrogenase: alcohol dehydrogenase (acceptor)
Alcohol dehydrogenase (acceptor)
In enzymology, an alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are primary alcohol and acceptor, whereas its two products are aldehyde and reduced acceptor....

: pyridoxine 5-dehydrogenase
Pyridoxine 5-dehydrogenase
In enzymology, a pyridoxine 5-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are pyridoxine and acceptor, whereas its two products are isopyridoxal and reduced acceptor....

: glucose dehydrogenase (acceptor)
Glucose dehydrogenase (acceptor)
In enzymology, a glucose dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-glucose and acceptor, whereas its two products are D-glucono-1,5-lactone and reduced acceptor....

: fructose 5-dehydrogenase
Fructose 5-dehydrogenase
In enzymology, a fructose 5-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-fructose and acceptor, whereas its two products are 5-dehydro-D-fructose and reduced acceptor....

: sorbose dehydrogenase
Sorbose dehydrogenase
In enzymology, a sorbose dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-sorbose and acceptor, whereas its two products are 5-dehydro-D-fructose and reduced acceptor....

: glucoside 3-dehydrogenase
Glucoside 3-dehydrogenase
In enzymology, a glucoside 3-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are sucrose and acceptor, whereas its two products are 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside and reduced acceptor.This enzyme belongs to the family of...

: glycolate dehydrogenase
Glycolate dehydrogenase
In enzymology, a glycolate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glycolate and acceptor, whereas its two products are glyoxylate and reduced acceptor....

: now *EC 1.7.99.5: malate dehydrogenase (acceptor)
Malate dehydrogenase (acceptor)
In enzymology, a malate dehydrogenase is an enzyme that catalyzes the chemical reaction-malate + acceptor \rightleftharpoons oxaloacetate + reduced acceptor...

: now *EC 1.1.5.2: cellobiose dehydrogenase (acceptor)
Cellobiose dehydrogenase (acceptor)
In enzymology, a cellobiose dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cellobiose and acceptor, whereas its two products are cellobiono-1,5-lactone and reduced acceptor....

: uracil dehydrogenase: alkan-1-ol dehydrogenase (acceptor)
Alkan-1-ol dehydrogenase (acceptor)
In enzymology, an alkan-1-ol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are primary alcohol and acceptor, whereas its two products are aldehyde and reduced acceptor....

: D-sorbitol dehydrogenase (acceptor)
D-sorbitol dehydrogenase (acceptor)
In enzymology, a D-sorbitol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-sorbitol and acceptor, whereas its two products are L-sorbose and reduced acceptor....

: glycerol dehydrogenase (acceptor)
Glycerol dehydrogenase (acceptor)
In enzymology, a glycerol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glycerol and acceptor, whereas its two products are glycerone and reduced acceptor....

: polyvinyl-alcohol dehydrogenase (acceptor)
Polyvinyl-alcohol dehydrogenase (acceptor)
In enzymology, a polyvinyl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are polyvinyl alcohol and acceptor, whereas its two products are oxidized polyvinyl alcohol and reduced acceptor.This enzyme belongs to the family of...

: hydroxyacid-oxoacid transhydrogenase
Hydroxyacid-oxoacid transhydrogenase
In enzymology, a hydroxyacid-oxoacid transhydrogenase is an enzyme that catalyzes the chemical reaction-3-hydroxybutanoate + 2-oxoglutarate \rightleftharpoons acetoacetate + -2-hydroxyglutarate...

: quinate dehydrogenase (pyrroloquinoline-quinone)
Quinate dehydrogenase (pyrroloquinoline-quinone)
In enzymology, a quinate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are quinate and pyrroloquinoline-quinone, whereas its two products are 3-dehydroquinate and reduced pyrroloquinoline-quinone.This enzyme belongs to the family of...

: 3-hydroxycyclohexanone dehydrogenase
3-hydroxycyclohexanone dehydrogenase
In enzymology, a 3-hydroxycyclohexanone dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-hydroxycyclohexanone and acceptor, whereas its two products are cyclohexane-1,3-dione and reduced acceptor....

: (R)-pantolactone dehydrogenase (flavin)
(R)-pantolactone dehydrogenase (flavin)
In enzymology, a -pantolactone dehydrogenase is an enzyme that catalyzes the chemical reaction-pantolactone + acceptor \rightleftharpoons 2-dehydropantolactone + reduced acceptor...

: glucose-fructose oxidoreductase
Glucose-fructose oxidoreductase
In enzymology, a glucose-fructose oxidoreductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-glucose and D-fructose, whereas its two products are D-gluconolactone and D-glucitol....

: pyranose dehydrogenase (acceptor): 2-oxoacid reductase: (S)-mandelate dehydrogenase
(S)-mandelate dehydrogenase
In enzymology, a -mandelate dehydrogenase is an enzyme that catalyzes the chemical reaction-2-hydroxy-2-phenylacetate + acceptor \rightleftharpoons 2-oxo-2-phenylacetate + reduced acceptor...

: L-sorbose 1-dehydrogenase

EC 1.2.1 With NAD or NADP as acceptor

: deleted, replaced by *EC 1.1.1.284 and *EC 4.4.1.22: formate dehydrogenase
Formate dehydrogenase
Formate dehydrogenases are a set of enzymes that catalyse the oxidation of formate to bicarbonate, donating the electrons to a second substrate, such as NAD+ in formate:NAD+ oxidoreductase or to a cytochrome in formate:ferricytochrome-b1 oxidoreductase .-Biological function:NAD-dependent formate...

: aldehyde dehydrogenase (NAD+)
Aldehyde dehydrogenase (NAD+)
In enzymology, an aldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are aldehyde, NAD+, and H2O, whereas its 3 products are acid, NADH, and H+....

: aldehyde dehydrogenase (NADP+)
Aldehyde dehydrogenase (NADP+)
In enzymology, an aldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are aldehyde, NADP+, and H2O, whereas its 3 products are acid, NADPH, and H+....

: aldehyde dehydrogenase (NAD(P)+)
Aldehyde dehydrogenase (NAD(P)+)
In enzymology, an aldehyde dehydrogenase [NAD+] is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are aldehyde, NAD+, NADP+, and H2O, whereas its 4 products are acid, NADH, NADPH, and H+....

: deleted: benzaldehyde dehydrogenase (NADP+)
Benzaldehyde dehydrogenase (NADP+)
In enzymology, a benzaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are benzaldehyde, NADP+, and H2O, whereas its 3 products are benzoate, NADPH, and H+....

: betaine-aldehyde dehydrogenase
Betaine-aldehyde dehydrogenase
In enzymology, a betaine-aldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are betaine aldehyde, NAD+, and H2O, whereas its 3 products are betaine, NADH, and H+....

: glyceraldehyde-3-phosphate dehydrogenase (NADP+): acetaldehyde dehydrogenase (acetylating): aspartate-semialdehyde dehydrogenase
Aspartate-semialdehyde dehydrogenase
In enzymology, an aspartate-semialdehyde dehydrogenase is an enzyme that is very important in the biosynthesis of amino acids in prokaryotes, fungi, and some higher plants. It forms an early branch point in the metabolic pathway forming lysine, methionine, leucine and isoleucine from aspartate...

: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
In enzymology, a glyceraldehyde-3-phosphate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-glyceraldehyde 3-phosphate, phosphate, and NAD+, whereas its 3 products are 3-phospho-D-glyceroyl phosphate, NADH, and H+.This enzyme belongs to the...

: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
Glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
In enzymology, a glyceraldehyde-3-phosphate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-glyceraldehyde 3-phosphate, phosphate, and NADP+, whereas its 3 products are 3-phospho-D-glyceroyl phosphate, NADPH, and H+.- Function :This enzyme...

: now *EC 1.1.1.205: malonate-semialdehyde dehydrogenase
Malonate-semialdehyde dehydrogenase
In enzymology, a malonate-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 3-oxopropanoate, NAD+, NADP+, and H2O, whereas its 4 products are malonate, NADH, NADPH, and H+....

: succinate-semialdehyde dehydrogenase (NAD(P)+)
Succinate-semialdehyde dehydrogenase (NAD(P)+)
In enzymology, a succinate-semialdehyde dehydrogenase [NAD+] is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are succinate semialdehyde, NAD+, NADP+, and H2O, whereas its 4 products are succinate, NADH, NADPH, and H+....

: glyoxylate dehydrogenase (acylating)
Glyoxylate dehydrogenase (acylating)
In enzymology, a glyoxylate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are glyoxylate, CoA, and NADP+, whereas its 3 products are oxalyl-CoA, NADPH, and H+....

: malonate-semialdehyde dehydrogenase (acetylating)
Malonate-semialdehyde dehydrogenase (acetylating)
In enzymology, a malonate-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 3-oxopropanoate, CoA, NAD+, and NADP+, whereas its 4 products are acetyl-CoA, CO2, NADH, and NADPH....

: aminobutyraldehyde dehydrogenase
Aminobutyraldehyde dehydrogenase
In enzymology, an aminobutyraldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-aminobutanal, NAD+, and H2O, whereas its 3 products are 4-aminobutanoate, NADH, and H+....

: glutarate-semialdehyde dehydrogenase
Glutarate-semialdehyde dehydrogenase
In enzymology, a glutarate-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are glutarate semialdehyde, NAD+, and H2O, whereas its 3 products are glutarate, NADH, and H+....

: glycolaldehyde dehydrogenase
Glycolaldehyde dehydrogenase
In enzymology, a glycolaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are glycolaldehyde, NAD+, and H2O, whereas its 3 products are glycolate, NADH, and H+....

: lactaldehyde dehydrogenase
Lactaldehyde dehydrogenase
In enzymology, a lactaldehyde dehydrogenase is an enzyme that catalyzes the chemical reaction-lactaldehyde + NAD+ + H2O \rightleftharpoons -lactate + NADH + 2 H+...

: 2-oxoaldehyde dehydrogenase (NAD+)
2-oxoaldehyde dehydrogenase (NAD+)
In enzymology, a 2-oxoaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-oxoaldehyde, NAD+, and H2O, whereas its 3 products are 2-oxo acid, NADH, and H+....

: succinate-semialdehyde dehydrogenase
Succinate-semialdehyde dehydrogenase
In enzymology, a succinate-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are succinate semialdehyde, NAD+, and H2O, whereas its 3 products are succinate, NADH, and H+....

: 2-oxoisovalerate dehydrogenase (acylating)
2-oxoisovalerate dehydrogenase (acylating)
In enzymology, a 2-oxoisovalerate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 3-methyl-2-oxobutanoate, CoA, and NAD+, whereas its 3 products are 2-methylpropanoyl-CoA, CO2, and NADH....

: 2,5-dioxovalerate dehydrogenase
2,5-dioxovalerate dehydrogenase
In enzymology, a 2,5-dioxovalerate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2,5-dioxopentanoate, NADP+, and H2O, whereas its 3 products are 2-oxoglutarate, NADPH, and H+....

: methylmalonate-semialdehyde dehydrogenase (acylating)
Methylmalonate-semialdehyde dehydrogenase (acylating)
In enzymology, a methylmalonate-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2-methyl-3-oxopropanoate, CoA, H2O, and NAD+, whereas its 3 products are propanoyl-CoA, HCO3-, and NADH.This enzyme belongs to the family of...

: benzaldehyde dehydrogenase (NAD+)
Benzaldehyde dehydrogenase (NAD+)
In enzymology, a benzaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are benzaldehyde, NAD+, and H2O, whereas its 3 products are benzoate, NADH, and H+....

: aryl-aldehyde dehydrogenase
Aryl-aldehyde dehydrogenase
In enzymology, an aryl-aldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are aromatic aldehyde, NAD+, and H2O, whereas its 3 products are aromatic acid, NADH, and H+....

: aryl-aldehyde dehydrogenase (NADP+)
Aryl-aldehyde dehydrogenase (NADP+)
In enzymology, an aryl-aldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are aromatic aldehyde, NADP+, AMP, diphosphate, and H2O, whereas its 4 products are aromatic acid, NADPH, H+, and ATP....

: L-aminoadipate-semialdehyde dehydrogenase
L-aminoadipate-semialdehyde dehydrogenase
In enzymology, a L-aminoadipate-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are L-2-aminoadipate 6-semialdehyde, NAD+, NADP+, and H2O, whereas its 4 products are L-2-aminoadipate, NADH, NADPH, and H+.This enzyme belongs to the family...

: aminomuconate-semialdehyde dehydrogenase
Aminomuconate-semialdehyde dehydrogenase
In enzymology, an aminomuconate-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-aminomuconate 6-semialdehyde, NAD+, and H2O, whereas its 3 products are 2-aminomuconate, NADH, and H+....

: (R)-dehydropantoate dehydrogenase
(R)-dehydropantoate dehydrogenase
In enzymology, a -dehydropantoate dehydrogenase is an enzyme that catalyzes the chemical reaction-4-dehydropantoate + NAD+ + H2O \rightleftharpoons -3,3-dimethylmalate + NADH + 2 H+...

: deleted, included in *EC 1.1.1.131: now *EC 1.1.1.203: retinal dehydrogenase
Retinal dehydrogenase
In enzymology, a retinal dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are retinal, NAD+, and H2O, whereas its 3 products are retinoic acid, NADH, and H+....

: now *EC 1.1.1.204: N-acetyl-g-glutamyl-phosphate reductase: phenylacetaldehyde dehydrogenase
Phenylacetaldehyde dehydrogenase
In enzymology, a phenylacetaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are phenylacetaldehyde, NAD+, and H2O, whereas its 3 products are phenylacetate, NADH, and H+....

: 3a,7a,12a-trihydroxycholestan-26-al 26-oxidoreductase: glutamate-5-semialdehyde dehydrogenase
Glutamate-5-semialdehyde dehydrogenase
In enzymology, a glutamate-5-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-glutamate 5-semialdehyde, phosphate, and NADP+, whereas its 3 products are L-glutamyl 5-phosphate, NADPH, and H+....

: hexadecanal dehydrogenase (acylating)
Hexadecanal dehydrogenase (acylating)
In enzymology, a hexadecanal dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are hexadecanal, CoA, and NAD+, whereas its 3 products are hexadecanoyl-CoA, NADH, and H+....

: formate dehydrogenase (NADP+)
Formate dehydrogenase (NADP+)
In enzymology, a formate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are formate and NADP+, whereas its two products are CO2 and NADPH....

: cinnamoyl-CoA reductase
Cinnamoyl-CoA reductase
In enzymology, a cinnamoyl-CoA reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are cinnamaldehyde, CoA, and NADP+, whereas its 3 products are cinnamoyl-CoA, NADPH, and H+....

: 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase
In enzymology, a 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde, NADP+, and H2O, whereas its 3 products are 4-carboxy-2-hydroxy-cis,cis-muconate,...

: formaldehyde dehydrogenase
Formaldehyde dehydrogenase
In enzymology, a formaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are formaldehyde, NAD+, and H2O, whereas its 3 products are formate, NADH, and H+....

: 4-trimethylammoniobutyraldehyde dehydrogenase
4-trimethylammoniobutyraldehyde dehydrogenase
In enzymology, a 4-trimethylammoniobutyraldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-trimethylammoniobutanal, NAD+, and H2O, whereas its 3 products are 4-trimethylammoniobutanoate, NADH, and H+.This enzyme belongs to the family of...

: long-chain-aldehyde dehydrogenase
Long-chain-aldehyde dehydrogenase
Long-chain-aldehyde dehydrogenase is an aldehyde dehydrogenase enzyme associated with Sjögren-Larsson syndrome.-External links:...

: 2-oxoaldehyde dehydrogenase (NADP+)
2-oxoaldehyde dehydrogenase (NADP+)
In enzymology, a 2-oxoaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-oxoaldehyde, NADP+, and H2O, whereas its 3 products are 2-oxo acid, NADPH, and H+....

: long-chain-fatty-acyl-CoA reductase
Long-chain-fatty-acyl-CoA reductase
In enzymology, a long-chain-fatty-acyl-CoA reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are long-chain aldehyde, CoA, and NADP+, whereas its 3 products are long-chain acyl-CoA, NADPH, and H+....

: pyruvate dehydrogenase (NADP+)
Pyruvate dehydrogenase (NADP+)
Pyruvate dehydrogenase is an enzyme that should not be confused with Pyruvate dehydrogenase .It catalyzes the following reaction:...

: oxoglutarate dehydrogenase (NADP+)
Oxoglutarate dehydrogenase (NADP+)
In enzymology, an oxoglutarate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-oxoglutarate, CoA, and NADP+, whereas its 3 products are succinyl-CoA, CO2, and NADPH....

: 4-hydroxyphenylacetaldehyde dehydrogenase
4-hydroxyphenylacetaldehyde dehydrogenase
In enzymology, a 4-hydroxyphenylacetaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-hydroxyphenylacetaldehyde, NAD+, and H2O, whereas its 3 products are 4-hydroxyphenylacetate, NADH, and H+....

: g-guanidinobutyraldehyde dehydrogenase: now *EC 1.1.1.279: now *EC 1.1.1.280: butanal dehydrogenase
Butanal dehydrogenase
In enzymology, a butanal dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are butanal, CoA, NAD+, and NADP+, whereas its 4 products are butanoyl-CoA, NADH, NADPH, and H+....

: phenylglyoxylate dehydrogenase (acylating)
Phenylglyoxylate dehydrogenase (acylating)
In enzymology, a phenylglyoxylate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are phenylglyoxylate, NAD+, and CoA-SH, whereas its 3 products are benzoyl-S-CoA, CO2, and NADH....

: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+)
Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+)
In enzymology, a glyceraldehyde-3-phosphate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are D-glyceraldehyde 3-phosphate, phosphate, NAD+, and NADP+, whereas its 4 products are 3-phospho-D-glyceroyl phosphate, NADH, NADPH, and H+.This enzyme...

: 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
In enzymology, a 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 5-carboxymethyl-2-hydroxymuconate semialdehyde, H2O, and NAD+, whereas its 3 products are 5-carboxymethyl-2-hydroxymuconate, NADH, and...

: 4-hydroxymuconic-semialdehyde dehydrogenase
4-hydroxymuconic-semialdehyde dehydrogenase
In enzymology, a 4-hydroxymuconic-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-hydroxymuconic semialdehyde, NAD+, and H2O, whereas its 3 products are maleylacetate, NADH, and H+....

: 4-formylbenzenesulfonate dehydrogenase
4-formylbenzenesulfonate dehydrogenase
In enzymology, a 4-formylbenzenesulfonate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-formylbenzenesulfonate, NAD+, and H2O, whereas its 3 products are 4-sulfobenzoate, NADH, and H+....

: 6-oxohexanoate dehydrogenase
6-oxohexanoate dehydrogenase
In enzymology, a 6-oxohexanoate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 6-oxohexanoate, NADP+, and H2O, whereas its 3 products are adipate, NADPH, and H+....

: 4-hydroxybenzaldehyde dehydrogenase
4-hydroxybenzaldehyde dehydrogenase
In enzymology, a 4-hydroxybenzaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-hydroxybenzaldehyde, NAD+, and H2O, whereas its 3 products are 4-hydroxybenzoate, NADH, and H+....

: salicylaldehyde dehydrogenase
Salicylaldehyde dehydrogenase
In enzymology, a salicylaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are salicylaldehyde, NAD+, and H2O, whereas its 3 products are salicylate, NADH, and H+....

: mycothiol-dependent formaldehyde dehydrogenase
Mycothiol-dependent formaldehyde dehydrogenase
In enzymology, a mycothiol-dependent formaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are formaldehyde, mycothiol, and NAD+, whereas its 3 products are S-formylmycothiol, NADH, and H+....

: vanillin dehydrogenase
Vanillin dehydrogenase
In enzymology, a vanillin dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are vanillin, NAD+, and H2O, whereas its 3 products are vanillate, NADH, and H+....

: coniferyl-aldehyde dehydrogenase
Coniferyl-aldehyde dehydrogenase
In enzymology, a coniferyl-aldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are coniferyl aldehyde, H2O, NAD+, and NADP+, whereas its 4 products are ferulate, NADH, NADPH, and H+....

: fluoroacetaldehyde dehydrogenase
Fluoroacetaldehyde dehydrogenase
In enzymology, a fluoroacetaldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are fluoroacetaldehyde, NAD+, and H2O, whereas its 3 products are fluoroacetate, NADH, and H+....

: glutamyl-tRNA reductase
Glutamyl-tRNA reductase
A glutamyl-tRNA reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-glutamate 1-semialdehyde, NADP+, and tRNA, whereas its 3 products are L-glutamyl-tRNA, NADPH, and H+....


EC 1.2.2 With a cytochrome as acceptor

: formate dehydrogenase (cytochrome)
Formate dehydrogenase (cytochrome)
In enzymology, a formate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are formate and ferricytochrome b1, whereas its 3 products are CO2, ferrocytochrome b1, and H+....

: pyruvate dehydrogenase (cytochrome)
Pyruvate dehydrogenase (cytochrome)
In enzymology, a pyruvate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are pyruvate, ferricytochrome b1, and H2O, whereas its 3 products are acetate, CO2, and ferrocytochrome b1....

: formate dehydrogenase (cytochrome-c-553)
Formate dehydrogenase (cytochrome-c-553)
In enzymology, a formate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are formate and ferricytochrome c-553, whereas its two products are CO2 and ferrocytochrome c-553....

: carbon-monoxide dehydrogenase (cytochrome b-561)
Carbon-monoxide dehydrogenase (cytochrome b-561)
In enzymology, a carbon-monoxide dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are CO, H2O, and ferricytochrome b-561, whereas its 3 products are CO2, H+, and ferrocytochrome b-561....


EC 1.2.3 With oxygen as acceptor

: aldehyde oxidase
Aldehyde oxidase
Aldehyde oxidase is an enzyme which generates carboxylic acids from aldehydes. It catalyzes the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide.* an aldehyde + H2O + O2 a carboxylate + H2O2 + H+...

: now *EC 1.1.3.22: pyruvate oxidase
Pyruvate oxidase
In enzymology, a pyruvate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are pyruvate, phosphate, and O2, whereas its 3 products are acetyl phosphate, CO2, and H2O2....

: oxalate oxidase
Oxalate oxidase
In enzymology, an oxalate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are oxalate, O2, and H+, whereas its two products are CO2 and H2O2....

: glyoxylate oxidase
Glyoxylate oxidase
In enzymology, a glyoxylate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are glyoxylate, H2O, and O2, whereas its two products are oxalate and H2O2....

: pyruvate oxidase (CoA-acetylating)
Pyruvate oxidase (CoA-acetylating)
In enzymology, a pyruvate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are pyruvate, CoA, and O2, whereas its 3 products are acetyl-CoA, CO2, and H2O2....

: indole-3-acetaldehyde oxidase
Indole-3-acetaldehyde oxidase
In enzymology, an indole-3-acetaldehyde oxidase is an enzyme that catalyzes the chemical reactionacetaldehyde + H2O + O2 \rightleftharpoons acetate + H2O2...

: pyridoxal oxidase
Pyridoxal oxidase
In enzymology, a pyridoxal oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are pyridoxal, H2O, and O2, whereas its product is 4-pyridoxate....

: aryl-aldehyde oxidase
Aryl-aldehyde oxidase
In enzymology, an aryl-aldehyde oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are aromatic aldehyde, O2, and H2O, whereas its two products are aromatic carboxylic acid and H2O2....

: deleted: retinal oxidase
Retinal oxidase
In enzymology, a retinal oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are retinal, O2, and H2O, whereas its two products are retinoic acid and H2O2....

: now *EC 1.14.13.82: 4-hydroxyphenylpyruvate oxidase
4-hydroxyphenylpyruvate oxidase
In enzymology, a 4-hydroxyphenylpyruvate oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 4-hydroxyphenylpyruvate and O2, whereas its two products are 4-hydroxyphenylacetate and CO2....

: Abscisic-aldehyde oxidase
Abscisic-aldehyde oxidase
In enzymology, an abscisic-aldehyde oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are abscisic aldehyde, H2O, and O2, whereas its two products are abscisate and H2O2....


EC 1.2.4 With a disulfide as acceptor

: pyruvate dehydrogenase (acetyl-transferring)
Pyruvate dehydrogenase (acetyl-transferring)
In enzymology, a pyruvate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are pyruvate and...

: oxoglutarate dehydrogenase (succinyl-transferring): deleted, included in EC 1.2.4.4: 3-methyl-2-oxobutanoate dehydrogenase
3-methyl-2-oxobutanoate dehydrogenase
In enzymology, a 3-methyl-2-oxobutanoate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 3-methyl-2-oxobutanoate, dihydrolipoyllysine-residue transferase, and lipoyllysine, whereas its 3 products are dihydrolipoyllysine-residue transferase,...


EC 1.2.7 With an iron-sulfur protein as acceptor

: pyruvate synthase
Pyruvate synthase
In enzymology, a pyruvate synthase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are pyruvate, CoA, and oxidized ferredoxin, whereas its 4 products are acetyl-CoA, CO2, reduced ferredoxin, and H+....

: 2-oxobutyrate synthase
2-oxobutyrate synthase
In enzymology, a 2-oxobutyrate synthase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-oxobutanoate, CoA, and oxidized ferredoxin, whereas its 3 products are propanoyl-CoA, CO2, and reduced ferredoxin....

: 2-oxoglutarate synthase
2-oxoglutarate synthase
In enzymology, a 2-oxoglutarate synthase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-oxoglutarate, CoA, and oxidized ferredoxin, whereas its 3 products are succinyl-CoA, CO2, and reduced ferredoxin....

: carbon-monoxide dehydrogenase (ferredoxin)
Carbon-monoxide dehydrogenase (ferredoxin)
In enzymology, a carbon-monoxide dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are CO, H2O, and oxidized ferredoxin, whereas its two products are CO2 and reduced ferredoxin....

: aldehyde ferredoxin oxidoreductase
Aldehyde ferredoxin oxidoreductase
In enzymology, an aldehyde ferredoxin oxidoreductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are aldehyde, H2O, and oxidized ferredoxin, whereas its 3 products are acid, H+, and reduced ferredoxin....

: glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)
Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)
In enzymology, a glyceraldehyde-3-phosphate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-glyceraldehyde-3-phosphate, H2O, and oxidized ferredoxin, whereas its 3 products are 3-phospho-D-glycerate, H+, and reduced ferredoxin.This enzyme...

: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
In enzymology, a 3-methyl-2-oxobutanoate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 3-methyl-2-oxobutanoate, CoA, and oxidized ferredoxin, whereas its 3 products are S--CoA, CO2, and reduced ferredoxin.This enzyme belongs to the family of...

: indolepyruvate ferredoxin oxidoreductase
Indolepyruvate ferredoxin oxidoreductase
In enzymology, an indolepyruvate ferredoxin oxidoreductase is an enzyme that catalyzes the chemical reactionpyruvate + CoA + oxidized ferredoxin \rightleftharpoons S-2-acetyl-CoA + CO2 + reduced ferredoxin...

: deleted, identical to *EC 1.2.7.3

EC 1.2.99 With other acceptors

: now *EC 1.1.99.19: carbon-monoxide dehydrogenase (acceptor)
Carbon-monoxide dehydrogenase (acceptor)
In enzymology, carbon monoxide dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are CO, H2O, and A, whereas its two products are CO2 and AH2....

: aldehyde dehydrogenase (pyrroloquinoline-quinone)
Aldehyde dehydrogenase (pyrroloquinoline-quinone)
In enzymology, an aldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are aldehyde, acceptor, and H2O, whereas its two products are carboxylate and reduced acceptor....

: formaldehyde dismutase
Formaldehyde dismutase
In enzymology, a formaldehyde dismutase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, formaldehyde, and two products, formate and methanol....

: formylmethanofuran dehydrogenase
Formylmethanofuran dehydrogenase
In enzymology, a formylmethanofuran dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are formylmethanofuran, H2O, and acceptor, whereas its 3 products are CO2, methanofuran, and reduced acceptor....

: carboxylate reductase
Carboxylate reductase
In enzymology, a carboxylate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are aldehyde, acceptor, and H2O, whereas its two products are carboxylate and reduced acceptor....

: aldehyde dehydrogenase (FAD-independent)
Aldehyde dehydrogenase (FAD-independent)
In enzymology, an aldehyde dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are aldehyde, H2O, and acceptor, whereas its two products are carboxylate and reduced acceptor....


EC 1.3.1 With NAD or NADP as acceptor

: dihydrouracil dehydrogenase (NAD+)
Dihydrouracil dehydrogenase (NAD+)
In enzymology, a dihydrouracil dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5,6-dihydrouracil and NAD+, whereas its 3 products are uracil, NADH, and H+....

: dihydropyrimidine dehydrogenase (NADP+)
Dihydropyrimidine dehydrogenase (NADP+)
In enzymology, a dihydropyrimidine dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5,6-dihydrouracil and NADP+, whereas its 3 products are uracil, NADPH, and H+....

: cortisone b-reductase: cortisone a-reductase: cucurbitacin D23-reductase: fumarate reductase (NADH)
Fumarate reductase (NADH)
In enzymology, a fumarate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are succinate and NAD+, whereas its 3 products are fumarate, NADH, and H+....

: meso-tartrate dehydrogenase
Meso-tartrate dehydrogenase
In enzymology, a meso-tartrate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are meso-tartaric acid and NAD+, whereas its 3 products are dihydroxyfumarate, NADH, and H+....

: acyl-CoA dehydrogenase (NADP+)
Acyl-CoA dehydrogenase (NADP+)
thumb|upright|alt = Rendering of Crotonyl CoA Carboxylase/Reductase, an oxidoreductase|Structure of Crotonyl CoA carboxylase/reductase. From Streptomycs collinus....

: enoyl-(acyl-carrier-protein) reductase (NADH): enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific)
Enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific)
In enzymology, an enoyl-[acyl-carrier-protein] reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are acyl-[acyl-carrier-protein] and NADP+, whereas its 3 products are trans-2,3-dehydroacyl-[acyl-carrier-protein], NADPH, and H+.This enzyme belongs...

: 2-coumarate reductase
2-coumarate reductase
In enzymology, a 2-coumarate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-propanoate and NAD+, whereas its 3 products are 2-coumarate, NADH, and H+....

: prephenate dehydrogenase
Prephenate dehydrogenase
In enzymology, a prephenate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are prephenate and NAD+, whereas its 3 products are 4-hydroxyphenylpyruvate, CO2, and NADH....

: prephenate dehydrogenase (NADP+)
Prephenate dehydrogenase (NADP+)
In enzymology, a prephenate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are prephenate and NADP+, whereas its 3 products are 4-hydroxyphenylpyruvate, CO2, and NADPH....

: orotate reductase (NADH)
Orotate reductase (NADH)
In enzymology, an orotate reductase is an enzyme that catalyzes the chemical reaction-dihydroorotate + NAD+ \rightleftharpoons orotate + NADH + H+...

: orotate reductase (NADPH)
Orotate reductase (NADPH)
In enzymology, an orotate reductase is an enzyme that catalyzes the chemical reaction-dihydroorotate + NADP+ \rightleftharpoons orotate + NADPH + H+...

: b-nitroacrylate reductase: 3-methyleneoxindole reductase
3-methyleneoxindole reductase
In enzymology, a 3-methyleneoxindole reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-methyl-1,3-dihydroindol-2-one and NADP+, whereas its three products are 3-methylene-1,3-dihydro-2H-indol-2-one, NADPH, and H+.This enzyme belongs to the...

: kynurenate-7,8-dihydrodiol dehydrogenase
Kynurenate-7,8-dihydrodiol dehydrogenase
In enzymology, a kynurenate-7,8-dihydrodiol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 7,8-dihydro-7,8-dihydroxykynurenate and NAD+, whereas its 3 products are 7,8-dihydroxykynurenate, NADH, and H+.This enzyme belongs to the family of...

: cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
In enzymology, a cis-1,2-dihydrobenzene-1,2-diol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-1,2-dihydrobenzene-1,2-diol and NAD+, whereas its 3 products are catechol, NADH, and H+....

: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
In enzymology, a trans-1,2-dihydrobenzene-1,2-diol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are trans-1,2-dihydrobenzene-1,2-diol and NADP+, whereas its three products are catechol, NADPH, and H+....

: 7-dehydrocholesterol reductase
7-dehydrocholesterol reductase
7-dehydrocholesterol reductase, also known as DHCR7, is a protein in humans which is encoded by the DHCR7 gene.-Function:The protein encoded by this gene is an enzyme catalyzing the production of cholesterol from 7-Dehydrocholesterol using NADPH....

: cholestenone 5a-reductase: cholestenone 5b-reductase: biliverdin reductase
Biliverdin reductase
Biliverdin reductase is an enzyme found in the liver that facilitates the conversion of biliverdin to bilirubin. It accomplishes this through the reduction of a double-bond between the second and third pyrrole ring into a single-bond....

: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
In enzymology, a 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase is an enzyme that catalyzes the chemical reaction-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ \rightleftharpoons catechol + CO2 + NADH + H+...

: dihydrodipicolinate reductase
Dihydrodipicolinate reductase
In enzymology, a dihydrodipicolinate reductase is an enzyme that catalyzes the chemical reaction-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD+ \rightleftharpoons 2,3-dihydrodipicolinate + NADH + H+...

: 2-hexadecenal reductase
2-hexadecenal reductase
In enzymology, a 2-hexadecenal reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are hexadecanal and NADP+, whereas its 3 products are 2-trans-hexadecenal, NADPH, and H+....

: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
In enzymology, a 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2,3-dihydro-2,3-dihydroxybenzoate and NAD+, whereas its 3 products are 2,3-dihydroxybenzoate, NADH, and H+.This enzyme belongs to the family...

: cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
In enzymology, a cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-1,2-dihydronaphthalene-1,2-diol and NAD+, whereas its 3 products are naphthalene-1,2-diol, NADH, and H+.This enzyme belongs to...

: progesterone 5a-reductase: 2-enoate reductase
2-enoate reductase
In enzymology, a 2-enoate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are butanoate and NAD+, whereas its 3 products are 2-butenoate, NADH, and H+....

: maleylacetate reductase
Maleylacetate reductase
In enzymology, a maleylacetate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 3-oxoadipate, NAD+, and NADP+, whereas its 4 products are 2-maleylacetate, NADH, NADPH, and H+....

: protochlorophyllide reductase
Protochlorophyllide reductase
In enzymology, a protochlorophyllide reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are chlorophyllide a and NADP+, whereas its 3 products are protochlorophyllide, NADPH, and H+....

: 2,4-dienoyl-CoA reductase (NADPH): phosphatidylcholine desaturase
Phosphatidylcholine desaturase
In enzymology, a phosphatidylcholine desaturase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine and NAD+, whereas its 3 products are 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine, NADH, and H+.This enzyme...

: geissoschizine dehydrogenase
Geissoschizine dehydrogenase
In enzymology, a geissoschizine dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are geissoschizine and NADP+, whereas its two products are 4,21-didehydrogeissoschizine and NADPH....

: cis-2-enoyl-CoA reductase (NADPH)
Cis-2-enoyl-CoA reductase (NADPH)
In enzymology, a cis-2-enoyl-CoA reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are acyl-CoA and NADP+, whereas its 3 products are cis-2,3-dehydroacyl-CoA, NADPH, and H+....

: trans-2-enoyl-CoA reductase (NADPH)
Trans-2-enoyl-CoA reductase (NADPH)
In enzymology, a trans-2-enoyl-CoA reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are acyl-CoA and NADP+, whereas its 3 products are trans-2,3-dehydroacyl-CoA, NADPH, and H+....

: enoyl-(acyl-carrier-protein) reductase (NADPH, A-specific)
Enoyl-(acyl-carrier-protein) reductase (NADPH, A-specific)
In enzymology, an enoyl-[acyl-carrier-protein] reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are acyl-[acyl-carrier-protein] and NADP+, whereas its 3 products are trans-2,3-dehydroacyl-[acyl-carrier-protein], NADPH, and H+.This enzyme belongs...

: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
In enzymology, a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2,6-dioxo-6-phenylhexanoate and NADP+, whereas its 3 products are 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate, NADPH, and H+.This enzyme...

: xanthommatin reductase
Xanthommatin reductase
In enzymology, a xanthommatin reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5,12-dihydroxanthommatin and NAD+, whereas its 3 products are xanthommatin, NADH, and H+....

: 12-oxophytodienoate reductase: arogenate dehydrogenase
Arogenate dehydrogenase
In enzymology, an arogenate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-arogenate and NAD+, whereas its 3 products are L-tyrosine, NADH, and CO2....

: trans-2-enoyl-CoA reductase (NAD+)
Trans-2-enoyl-CoA reductase (NAD+)
In enzymology, a trans-2-enoyl-CoA reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are acyl-CoA and NAD+, whereas its 3 products are trans-didehydroacyl-CoA, NADH, and H+....

: 2'-hydroxyisoflavone reductase
2'-hydroxyisoflavone reductase
In enzymology, a 2'-hydroxyisoflavone reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are vestitone and NADP+, whereas its 3 products are 2'-hydroxyformononetin, NADPH, and H+....

: biochanin-A reductase
Biochanin-A reductase
In enzymology, a biochanin-A reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are dihydrobiochanin A and NADP+, whereas its 3 products are biochanin A, NADPH, and H+....

: a-santonin 1,2-reductase: 15-oxoprostaglandin 13-oxidase
15-oxoprostaglandin 13-oxidase
In enzymology, a 15-oxoprostaglandin 13-oxidase is an enzyme that catalyzes the chemical reaction--11alpha-hydroxy-9,15-dioxoprostanoate + NAD+ \rightleftharpoons --11alpha-hydroxy-9,15-dioxoprosta-13-enoate + NADH + H+...

: cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
Cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
In enzymology, a cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase is an enzyme that catalyzes the chemical reaction-cis-3,4-dihydrophenanthrene-3,4-diol + NAD+ \rightleftharpoons phenanthrene-3,4-diol + NADH + H+...

: now *EC 1.1.1.252: 2'-hydroxydaidzein reductase
2'-hydroxydaidzein reductase
In enzymology, a 2'-hydroxydaidzein reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2'-hydroxy-2,3-dihydrodaidzein and NADP+, whereas its 3 products are 2'-hydroxydaidzein, NADPH, and H+....

: 2-methyl-branched-chain-enoyl-CoA reductase
2-methyl-branched-chain-enoyl-CoA reductase
In enzymology, a 2-methyl-branched-chain-enoyl-CoA reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-methylbutanoyl-CoA and NAD+, whereas its 3 products are 2-methylcrotonoyl-CoA, NADH, and H+....

: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
In enzymology, a -3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase is an enzyme that catalyzes the chemical reaction-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+ \rightleftharpoons 3,4-dihydroxybenzoate + CO2 + NADH...

: precorrin-6A reductase
Precorrin-6A reductase
In enzymology, a precorrin-6A reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are precorrin 6B and NADP+, whereas its 3 products are precorrin 6A, NADPH, and H+....

: now *EC 1.3.1.25: cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
In enzymology, a cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-3-phenylcyclohexa-3,5-diene-1,2-diol and NAD+, whereas its 3 products are biphenyl-2,3-diol, NADH, and H+.This enzyme belongs to the...

: phloroglucinol reductase
Phloroglucinol reductase
In enzymology, a phloroglucinol reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are dihydrophloroglucinol and NADP+, whereas its 3 products are phloroglucinol, NADPH, and H+....

: 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
In enzymology, a 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate and NAD+, whereas its 3 products are 2,3-dihydroxy-p-cumate, NADH, and H+.This...

: 1,2-dihydroxy-3-methyl-1,2-dihydrobenzoate dehydrogenase: dibenzothiophene dihydrodiol dehydrogenase
Dibenzothiophene dihydrodiol dehydrogenase
In enzymology, a dibenzothiophene dihydrodiol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene and NAD+, whereas its 3 products are 1,2-dihydroxydibenzothiophene, NADH, and H+.This enzyme...

: terephthalate 1,2-cis-dihydrodiol dehydrogenase
Terephthalate 1,2-cis-dihydrodiol dehydrogenase
In enzymology, a terephthalate 1,2-cis-dihydrodiol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-4,5-dihydroxycyclohexa-1,2-diene-1,4-dicarboxylate and NAD+, whereas its 3 products are 3,4-dihydroxybenzoate, CO2, and NADH.This enzyme...

: pimeloyl-CoA dehydrogenase
Pimeloyl-CoA dehydrogenase
In enzymology, a pimeloyl-CoA dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are pimeloyl-CoA and NAD+, whereas its 3 products are 6-carboxyhex-2-enoyl-CoA, NADH, and H+....

: 2,4-dichlorobenzoyl-CoA reductase
2,4-dichlorobenzoyl-CoA reductase
In enzymology, a 2,4-dichlorobenzoyl-CoA reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-chlorobenzoyl-CoA, NADP+, and HCl, whereas its 3 products are 2,4-dichlorobenzoyl-CoA, NADPH, and H+....

: phthalate 4,5-cis-dihydrodiol dehydrogenase
Phthalate 4,5-cis-dihydrodiol dehydrogenase
In enzymology, a phthalate 4,5-cis-dihydrodiol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-4,5-dihydroxycyclohexa-1,2-diene-1,2-dicarboxylate and NAD+, whereas its 3 products are 4,5-dihydroxyphthalate, NADH, and H+.This enzyme...

: 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase
In enzymology, a 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline and NAD+, whereas its 3 products are...

: cis-dihydroethylcatechol dehydrogenase
Cis-dihydroethylcatechol dehydrogenase
In enzymology, a cis-dihydroethylcatechol dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-1,2-dihydro-3-ethylcatechol and NAD+, whereas its 3 products are 3-ethylcatechol, NADH, and H+....

: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
Cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
In enzymology, a cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate, NAD+, and NADP+, whereas its 4 products are 4-methylcatechol,...

: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase
1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase
In enzymology, a 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate and NAD+, whereas its 3 products are 3-methylcatechol, NADH, and...

: zeatin reductase
Zeatin reductase
In enzymology, a zeatin reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are dihydrozeatin and NADP+, whereas its 3 products are zeatin, NADPH, and H+....

: D14-sterol reductase: D24(241)-sterol reductase: D24-sterol reductase: 1,2-dihydrovomilenine reductase
1,2-dihydrovomilenine reductase
In enzymology, a 1,2-dihydrovomilenine reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 17-O-acetylnorajmaline and NADP+, whereas its 3 products are 1,2-dihydrovomilenine, NADPH, and H+....

: 2-alkenal reductase
2-alkenal reductase
In enzymology, a 2-alkenal reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are n-alkanal, NAD+, and NADP+, whereas its 4 products are alk-2-enal, NADH, NADPH, and H+....

: divinyl chlorophyllide a 8-vinyl-reductase
Divinyl chlorophyllide a 8-vinyl-reductase
In enzymology, a divinyl chlorophyllide a 8-vinyl-reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are chlorophyllide a and NADP+, whereas its 3 products are divinyl chlorophyllide a, NADPH, and H+.This enzyme belongs to the family of...

: precorrin-2 dehydrogenase
Precorrin-2 dehydrogenase
In enzymology, a precorrin-2 dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are precorrin 2 and NAD+, whereas its 3 products are sirohydrochlorin, NADH, and H+....

: anthocyanidin reductase
Anthocyanidin reductase
In enzymology, an anthocyanidin reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are flavan-3-ol, NAD+, and NADP+, whereas its 4 products are anthocyanidin, NADH, NADPH, and H+....

: arogenate dehydrogenase (NADP+)
Arogenate dehydrogenase (NADP+)
In enzymology, an arogenate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-arogenate and NADP+, whereas its 3 products are L-tyrosine, NADPH, and CO2....

: arogenate dehydrogenase (NAD(P)+)
Arogenate dehydrogenase (NAD(P)+)
In enzymology, an arogenate dehydrogenase [NAD+] is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-arogenate, NAD+, and NADP+, whereas its 4 products are L-tyrosine, NADH, NADPH, and CO2....


EC 1.3.2 With a cytochrome as acceptor

: now EC 1.3.99.2: now EC 1.3.99.3: galactonolactone dehydrogenase

EC 1.3.3 With oxygen as acceptor

: dihydroorotate oxidase: lathosterol oxidase
Lathosterol oxidase
In enzymology, a lathosterol oxidase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are 5alpha-cholest-7-en-3beta-ol, NADH, NADPH, H+, and O2, whereas its 4 products are cholesta-5,7-dien-3beta-ol, NAD+, NADP+, and H2O....

: coproporphyrinogen oxidase: protoporphyrinogen oxidase
Protoporphyrinogen oxidase
Protoporphyrinogen oxidase is an enzyme that is responsible for the seventh step in heme production....

: bilirubin oxidase
Bilirubin oxidase
In enzymology, a bilirubin oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are bilirubin and O2, whereas its two products are biliverdin and H2O....

: acyl-CoA oxidase
Acyl-CoA oxidase
In enzymology, an acyl-CoA oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are acyl-CoA and O2, whereas its two products are trans-2,3-dehydroacyl-CoA and H2O2....

: dihydrouracil oxidase
Dihydrouracil oxidase
In enzymology, a dihydrouracil oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5,6-dihydrouracil and O2, whereas its two products are uracil and H2O2....

: tetrahydroberberine oxidase
Tetrahydroberberine oxidase
In enzymology, a tetrahydroberberine oxidase is an enzyme that catalyzes the chemical reaction-tetrahydroberberine + 2 O2 \rightleftharpoons berberine + 2 H2O2...

: secologanin synthase
Secologanin synthase
In enzymology, a secologanin synthase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are loganin, NADPH, H+, and O2, whereas its 3 products are secologanin, NADP+, and H2O....

: tryptophan a,b-oxidase: pyrroloquinoline-quinone synthase
Pyrroloquinoline-quinone synthase
In enzymology, a pyrroloquinoline-quinone synthase is an enzyme that catalyzes the chemical reactionThe two substrates of this enzyme are 6--7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate, and O2, whereas its 3 products are...


EC 1.3.5 With a quinone or related compound as acceptor

: succinate dehydrogenase (ubiquinone)

EC 1.3.7 With an iron-sulfur protein as acceptor

: 6-hydroxynicotinate reductase
6-hydroxynicotinate reductase
In enzymology, a 6-hydroxynicotinate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 6-oxo-1,4,5,6-tetrahydronicotinate and oxidized ferredoxin, whereas its two products are 6-hydroxynicotinate and reduced ferredoxin.This enzyme belongs to the...

: 15,16-dihydrobiliverdin:ferredoxin oxidoreductase
15,16-dihydrobiliverdin:ferredoxin oxidoreductase
In enzymology, a 15,16-dihydrobiliverdin:ferredoxin oxidoreductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 15,16-dihydrobiliverdin and oxidized ferredoxin, whereas its two products are biliverdin IXalpha and reduced ferredoxin.This enzyme...

: phycoerythrobilin:ferredoxin oxidoreductase
Phycoerythrobilin:ferredoxin oxidoreductase
In enzymology, a phycoerythrobilin:ferredoxin oxidoreductase is an enzyme that catalyzes the chemical reaction-phycoerythrobilin + oxidized ferredoxin \rightleftharpoons 15,16-dihydrobiliverdin + reduced ferredoxin...

: phytochromobilin:ferredoxin oxidoreductase
Phytochromobilin:ferredoxin oxidoreductase
In enzymology, a phytochromobilin:ferredoxin oxidoreductase is an enzyme that catalyzes the chemical reaction-phytochromobilin + oxidized ferredoxin \rightleftharpoons biliverdin IXalpha + reduced ferredoxin...

: phycocyanobilin:ferredoxin oxidoreductase
Phycocyanobilin:ferredoxin oxidoreductase
In enzymology, a phycocyanobilin:ferredoxin oxidoreductase is an enzyme that catalyzes the chemical reaction-phycocyanobilin + oxidized ferredoxin \rightleftharpoons biliverdin IXalpha + reduced ferredoxin...


EC 1.3.99 With other acceptors

: succinate dehydrogenase: butyryl-CoA dehydrogenase
Butyryl-CoA dehydrogenase
In enzymology, a butyryl-CoA dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are butanoyl-CoA and acceptor, whereas its two products are 2-butenoyl-CoA and reduced acceptor....

: acyl-CoA dehydrogenase: 3-oxosteroid 1-dehydrogenase
3-oxosteroid 1-dehydrogenase
In enzymology, a 3-oxosteroid 1-dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-oxosteroid and acceptor, whereas its two products are 3-oxo-Delta1-steroid and reduced acceptor....

: 3-oxo-5a-steroid 4-dehydrogenase: 3-oxo-5b-steroid 4-dehydrogenase: glutaryl-CoA dehydrogenase
Glutaryl-CoA dehydrogenase
Glutaryl-CoA dehydrogenase is an enzyme acting upon glutaryl-coenzyme A, creating crotonyl-coenzyme A.It plays a role in the metabolism of lysine, hydroxylysine and tryptophan.-Pathology:...

: 2-furoyl-CoA dehydrogenase
2-furoyl-CoA dehydrogenase
In enzymology, a 2-furoyl-CoA dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-furoyl-CoA, H2O, and acceptor, whereas its two products are S--CoA and reduced acceptor....

: now *EC 1.21.99.1: isovaleryl-CoA dehydrogenase
Isovaleryl-CoA dehydrogenase
In enzymology, an isovaleryl-CoA dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-methylbutanoyl-CoA and acceptor, whereas its two products are 3-methylbut-2-enoyl-CoA and reduced acceptor....

: dihydroorotate dehydrogenase
Dihydroorotate dehydrogenase
Dihydroorotate dehydrogenase is an enzyme that catalyzes the fourth step in the de novo biosynthesis of pyrimidine. It converts dihydroorotate to orotate:...

: 2-methylacyl-CoA dehydrogenase
2-methylacyl-CoA dehydrogenase
In enzymology, a 2-methylacyl-CoA dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-methylbutanoyl-CoA and acceptor, whereas its two products are 2-methylbut-2-enoyl-CoA and reduced acceptor....

: long-chain-acyl-CoA dehydrogenase
Long-chain-acyl-CoA dehydrogenase
In enzymology, a long-chain-acyl-CoA dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are acyl-CoA and acceptor, whereas its two products are 2,3-dehydroacyl-CoA and reduced acceptor....

: cyclohexanone dehydrogenase
Cyclohexanone dehydrogenase
In enzymology, a cyclohexanone dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cyclohexanone and acceptor, whereas its two products are cyclohex-2-enone and reduced acceptor....

: benzoyl-CoA reductase
Benzoyl-CoA reductase
In enzymology, a benzoyl-CoA reductase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are benzoyl-CoA, reduced acceptor, ATP, and H2O, whereas its 4 products are cyclohexa-1,5-diene-1-carbonyl-CoA, acceptor, ADP, and phosphate.This enzyme belongs to the family of...

: isoquinoline 1-oxidoreductase
Isoquinoline 1-oxidoreductase
In enzymology, an isoquinoline 1-oxidoreductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are isoquinoline, acceptor, and H2O, whereas its two products are isoquinolin-1-one and reduced acceptor....

: quinoline 2-oxidoreductase
Quinoline 2-oxidoreductase
In enzymology, a quinoline 2-oxidoreductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are quinoline, acceptor, and H2O, whereas its two products are quinolin-1-one and reduced acceptor....

: quinaldate 4-oxidoreductase
Quinaldate 4-oxidoreductase
In enzymology, a quinaldate 4-oxidoreductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are quinaldate, acceptor, and H2O, whereas its two products are kynurenate and reduced acceptor....

: quinoline-4-carboxylate 2-oxidoreductase
Quinoline-4-carboxylate 2-oxidoreductase
In enzymology, a quinoline-4-carboxylate 2-oxidoreductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are quinoline-4-carboxylate, acceptor, and H2O, whereas its two products are 2-oxo-1,2-dihydroquinoline-4-carboxylate and reduced acceptor.This enzyme belongs...

: 4-hydroxybenzoyl-CoA reductase
4-hydroxybenzoyl-CoA reductase
In enzymology, a 4-hydroxybenzoyl-CoA reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are benzoyl-CoA, acceptor, and H2O, whereas its two products are 4-hydroxybenzoyl-CoA and reduced acceptor....

: (R)-benzylsuccinyl-CoA dehydrogenase: coproporphyrinogen dehydrogenase
Coproporphyrinogen dehydrogenase
In enzymology, a coproporphyrinogen dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are coproporphyrinogen III and S-adenosyl-L-methionine, whereas its 4 products are protoporphyrinogen IX, CO2, L-methionine, and 5'-deoxyadenosine.This enzyme...


EC 1.4.1 With NAD or NADP as acceptor

: alanine dehydrogenase
Alanine dehydrogenase
In enzymology, an alanine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-alanine, H2O, and NAD+, whereas its 4 products are pyruvate, NH3, NADH, and H+....

: glutamate dehydrogenase
Glutamate dehydrogenase
Glutamate dehydrogenase is an enzyme, present in most microbes and the mitochondria of eukaryotes, as are some of the other enzymes required for urea synthesis, that converts glutamate to α-Ketoglutarate, and vice versa. In animals, the produced ammonia is, however, usually bled off to the urea...

: glutamate dehydrogenase (NAD(P)+): glutamate dehydrogenase (NADP+): L-amino-acid dehydrogenase
L-amino-acid dehydrogenase
In enzymology, a L-amino-acid dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-amino acid, H2O, and NAD+, whereas its 4 products are 2-oxo acid, NH3, NADH, and H+....

: deleted, included in *EC 1.4.4.1: serine 2-dehydrogenase
Serine 2-dehydrogenase
In enzymology, a serine 2-dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-serine, H2O, and NAD+, whereas its 4 products are 3-hydroxypyruvate, NH3, NADH, and H+....

: valine dehydrogenase (NADP+)
Valine dehydrogenase (NADP+)
In enzymology, a valine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-valine, H2O, and NADP+, whereas its 4 products are 3-methyl-2-oxobutanoate, NH3, NADPH, and H+....

: leucine dehydrogenase
Leucine dehydrogenase
In enzymology, a leucine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-leucine, H2O, and NAD+, whereas its 4 products are 4-methyl-2-oxopentanoate, NH3, NADH, and H+....

: glycine dehydrogenase
Glycine dehydrogenase
In enzymology, a glycine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are glycine, H2O, and NAD+, whereas its 4 products are glyoxylate, NH3, NADH, and H+....

: L-erythro-3,5-diaminohexanoate dehydrogenase
L-erythro-3,5-diaminohexanoate dehydrogenase
In enzymology, a L-erythro-3,5-diaminohexanoate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-erythro-3,5-diaminohexanoate, H2O, and NAD+, whereas its 4 products are -5-amino-3-oxohexanoate, NH3, NADH, and H+.This enzyme belongs to the family...

: 2,4-diaminopentanoate dehydrogenase
2,4-diaminopentanoate dehydrogenase
In enzymology, a 2,4-diaminopentanoate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2,4-diaminopentanoate, H2O, NAD+, and NADP+, whereas its 5 products are 2-amino-4-oxopentanoate, NH3, NADH, NADPH, and H+.This enzyme belongs to the family of...

: glutamate synthase (NADPH)
Glutamate synthase (NADPH)
In enzymology, a glutamate synthase is an enzyme that catalyzes the chemical reactionThus, the four substrates of this enzyme are L-glutamine, 2-oxoglutarate , NADPH, and H+, whereas the two products are L-glutamate and NADP+....

: glutamate synthase (NADH)
Glutamate synthase (NADH)
In enzymology, a glutamate synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-glutamate and NAD+, whereas its 4 products are L-glutamine, 2-oxoglutarate, NADH, and H+....

: lysine dehydrogenase
Lysine dehydrogenase
In enzymology, a lysine dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-lysine and NAD+, whereas its 4 products are 1,2-didehydropiperidine-2-carboxylate, NH3, NADH, and H+....

: diaminopimelate dehydrogenase
Diaminopimelate dehydrogenase
In enzymology, a diaminopimelate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are meso-2,6-diaminoheptanedioate, H2O, and NADP+, whereas its 4 products are L-2-amino-6-oxoheptanedioate, NH3, NADPH, and H+....

: N-methylalanine dehydrogenase
N-methylalanine dehydrogenase
In enzymology, a N-methylalanine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N-methyl-L-alanine, H2O, and NADP+, whereas its 4 products are pyruvate, methylamine, NADPH, and H+....

: lysine 6-dehydrogenase: tryptophan dehydrogenase
Tryptophan dehydrogenase
In enzymology, a tryptophan dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are L-tryptophan, NAD+, NADP+, and H2O, whereas its 5 products are pyruvate, NH3, NADH, NADPH, and H+....

: phenylalanine dehydrogenase
Phenylalanine dehydrogenase
In enzymology, a phenylalanine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-phenylalanine, H2O, and NAD+, whereas its 4 products are phenylpyruvate, NH3, NADH, and H+....

: aspartate dehydrogenase
Aspartate dehydrogenase
In enzymology, an aspartate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are L-aspartate, H2O, NAD+, and NADP+, whereas its 5 products are oxaloacetate, NH3, NADH, NADPH, and H+....


EC 1.4.3 With oxygen as acceptor

: D-aspartate oxidase
D-aspartate oxidase
In enzymology, a D-aspartate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-aspartate, H2O, and O2, whereas its 3 products are oxaloacetate, NH3, and H2O2....

: L-amino-acid oxidase
L-amino-acid oxidase
In enzymology, a L-amino-acid oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-amino acid, H2O, and O2, whereas its 3 products are 2-oxo acid, NH3, and H2O2....

: D-amino-acid oxidase: amine oxidase (flavin-containing): pyridoxamine-phosphate oxidase: amine oxidase (copper-containing)
Amine oxidase (copper-containing)
Amine oxidases are enzymes that catalyze the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. There are two classes of amine oxidases: flavin-containing and copper-containing . Copper-containing AO act as a disulphide-linked homodimer...

: D-glutamate oxidase
D-glutamate oxidase
In enzymology, a D-glutamate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-glutamate, H2O, and O2, whereas its 3 products are 2-oxoglutarate, NH3, and H2O2....

: ethanolamine oxidase
Ethanolamine oxidase
In enzymology, an ethanolamine oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are ethanolamine, H2O, and O2, whereas its 3 products are glycolaldehyde, NH3, and H2O2....

: deleted, included in *EC 1.4.3.4: putrescine oxidase
Putrescine oxidase
In enzymology, a putrescine oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are putrescine, O2, and H2O, whereas its 3 products are 4-aminobutanal, NH3, and H2O2....

: L-glutamate oxidase
L-glutamate oxidase
In enzymology, a L-glutamate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-glutamate, O2, and H2O, whereas its 3 products are 2-oxoglutarate, NH3, and H2O2....

: cyclohexylamine oxidase
Cyclohexylamine oxidase
In enzymology, a cyclohexylamine oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are cyclohexylamine, O2, and H2O, whereas its 3 products are cyclohexanone, NH3, and H2O2....

: protein-lysine 6-oxidase: L-lysine oxidase
L-lysine oxidase
In enzymology, a L-lysine oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-lysine, O2, and H2O, whereas its 3 products are 6-amino-2-oxohexanoate, NH3, and H2O2....

: D-glutamate(D-aspartate) oxidase
D-glutamate(D-aspartate) oxidase
In enzymology, a D-glutamate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are D-glutamate, H2O, and O2, whereas its 3 products are 2-oxoglutarate, NH3, and H2O2....

: L-aspartate oxidase
L-aspartate oxidase
In enzymology, a L-aspartate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-aspartate, H2O, and O2, whereas its 3 products are oxaloacetate, NH3, and H2O2....

: now *EC 1.3.3.10: deleted, not approved: glycine oxidase

EC 1.4.4 With a disulfide as acceptor

: now EC 1.21.4.1: glycine dehydrogenase (decarboxylating)
Glycine dehydrogenase (decarboxylating)
Glycine dehydrogenase [decarboxylating], mitochondrial also known as glycine cleavage system P protein or glycine decarboxylase is an enzyme that in humans is encoded by the GLDC gene.- Reaction :...


EC 1.4.99 With other acceptors

: D-amino acid dehydrogenase
D-amino acid dehydrogenase
D-amino-acid dehydrogenase is a bacterial enzyme that catalyses the oxidation of D-amino acids into their corresponding oxoacids. It contains both flavin and nonheme iron as cofactors...

: taurine dehydrogenase
Taurine dehydrogenase
In enzymology, a taurine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are taurine, H2O, and acceptor, whereas its 3 products are sulfoacetaldehyde, NH3, and reduced acceptor....

: amine dehydrogenase
Amine dehydrogenase
Amine Dehydrogenase , also known as methylamine dehydrogenase , is a tryptophan tryptophylquinone-dependent enzyme that catalyzes the oxidative deamination of a primary amine to an aldehyde and ammonia...

: aralkylamine dehydrogenase
Aralkylamine dehydrogenase
In enzymology, an aralkylamine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are RCH2NH2, H2O, and acceptor, whereas its 3 products are RCHO, NH3, and reduced acceptor....

: glycine dehydrogenase (cyanide-forming)
Glycine dehydrogenase (cyanide-forming)
In enzymology, a glycine dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glycine and A, whereas its 3 products are hydrogen cyanide, CO2, and AH2....


EC 1.5.1 With NAD
Nicotinamide adenine dinucleotide
Nicotinamide adenine dinucleotide, abbreviated NAD, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine base and the other nicotinamide.In metabolism, NAD is involved...

 or NADP as acceptor
Electron acceptor
An electron acceptor is a chemical entity that accepts electrons transferred to it from another compound. It is an oxidizing agent that, by virtue of its accepting electrons, is itself reduced in the process....

: pyrroline-2-carboxylate reductase
Pyrroline-2-carboxylate reductase
In enzymology, a pyrroline-2-carboxylate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-proline, NAD+, and NADP+, whereas its 4 products are 1-pyrroline-2-carboxylate, NADH, NADPH, and H+....

: pyrroline-5-carboxylate reductase
Pyrroline-5-carboxylate reductase
In enzymology, a pyrroline-5-carboxylate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-proline, NAD+, and NADP+, whereas its 4 products are 1-pyrroline-5-carboxylate, NADH, NADPH, and H+....

: dihydrofolate reductase
Dihydrofolate reductase
- Function :Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids...

: deleted, included in *EC 1.5.1.3: methylenetetrahydrofolate dehydrogenase (NADP+)
Methylenetetrahydrofolate dehydrogenase (NADP+)
In enzymology, a methylenetetrahydrofolate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5,10-methylenetetrahydrofolate and NADP+, whereas its 3 products are 5,10-methenyltetrahydrofolate, NADPH, and H+.This enzyme belongs to the family...

: formyltetrahydrofolate dehydrogenase
Formyltetrahydrofolate dehydrogenase
In enzymology, a formyltetrahydrofolate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 10-formyltetrahydrofolate, NADP+, and H2O, whereas its 4 products are tetrahydrofolate, CO2, NADPH, and H+....

: saccharopine dehydrogenase (NAD+, L-lysine-forming)
Saccharopine dehydrogenase (NAD+, L-lysine-forming)
In enzymology, a saccharopine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N6--L-lysine, NAD+, and H2O, whereas its 4 products are L-lysine, 2-oxoglutarate, NADH, and H+.This enzyme belongs to the family of oxidoreductases, specifically those...

: saccharopine dehydrogenase (NADP+, L-lysine-forming)
Saccharopine dehydrogenase (NADP+, L-lysine-forming)
In enzymology, a saccharopine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N6--L-lysine, NADP+, and H2O, whereas its 4 products are L-lysine, 2-oxoglutarate, NADPH, and H+.This enzyme belongs to the family of oxidoreductases, specifically...

: saccharopine dehydrogenase (NAD+, L-glutamate-forming)
Saccharopine dehydrogenase (NAD+, L-glutamate-forming)
In enzymology, a saccharopine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N6--L-lysine, NAD+, and H2O, whereas its 4 products are L-glutamate, 2-aminoadipate 6-semialdehyde, NADH, and H+.This enzyme belongs to the family of oxidoreductases,...

: saccharopine dehydrogenase (NADP+, L-glutamate-forming)
Saccharopine dehydrogenase (NADP+, L-glutamate-forming)
In enzymology, a saccharopine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N6--L-lysine, NADP+, and H2O, whereas its 4 products are L-glutamate, L-2-aminoadipate 6-semialdehyde, NADPH, and H+.This enzyme belongs to the family of...

: D-octopine dehydrogenase
D-octopine dehydrogenase
In enzymology, a D-octopine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N2--L-arginine, NAD+, and H2O, whereas its 4 products are L-arginine, pyruvate, NADH, and H+....

: 1-pyrroline-5-carboxylate dehydrogenase
1-Pyrroline-5-carboxylate dehydrogenase
In enzymology, a 1-pyrroline-5-carboxylate dehydrogenase is an enzyme that catalyzes the chemical reactionThe three substrates of this enzyme are -1-pyrroline-5-carboxylate, NAD+, and H2O, whereas its three products are glutamate, NADH, and H+....

: now *EC 1.17.1.5: deleted, included in *EC 1.5.1.21: methylenetetrahydrofolate dehydrogenase (NAD+)
Methylenetetrahydrofolate dehydrogenase (NAD+)
In enzymology, a methylenetetrahydrofolate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5,10-methylenetetrahydrofolate and NAD+, whereas its 3 products are 5,10-methenyltetrahydrofolate, NADH, and H+.This enzyme belongs to the family...

: D-lysopine dehydrogenase
D-lysopine dehydrogenase
In enzymology, a D-lysopine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N2--L-lysine, NADP+, and H2O, whereas its 4 products are L-lysine, pyruvate, NADPH, and H+....

: alanopine dehydrogenase
Alanopine dehydrogenase
In enzymology, an alanopine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2,2'-iminodipropanoate, NAD+, and H2O, whereas its 4 products are L-alanine, pyruvate, NADH, and H+....

: ephedrine dehydrogenase
Ephedrine dehydrogenase
In enzymology, an ephedrine dehydrogenase is an enzyme that catalyzes the chemical reaction-ephedrine + NAD+ \rightleftharpoons -2-methylimino-1-phenylpropan-1-ol + NADH + H+...

: D-nopaline dehydrogenase
D-nopaline dehydrogenase
In enzymology, a D-nopaline dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N2--L-arginine, NADP+, and H2O, whereas its 4 products are L-arginine, 2-oxoglutarate, NADPH, and H+....

: methylenetetrahydrofolate reductase (NAD(P)H): D1-piperideine-2-carboxylate reductase: strombine dehydrogenase
Strombine dehydrogenase
In enzymology, a strombine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N--D-alanine, NAD+, and H2O, whereas its 4 products are glycine, pyruvate, NADH, and H+....

: tauropine dehydrogenase
Tauropine dehydrogenase
In enzymology, a tauropine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 products of this enzyme are tauropine, NAD+, and H2O, whereas its 4 substrates are taurine, pyruvate, NADH, and H+....

: N5-(carboxyethyl)ornithine synthase
N5-(carboxyethyl)ornithine synthase
In enzymology, a N5-ornithine synthase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N5--L-ornithine, NADP+, and H2O, whereas its 4 products are L-ornithine, pyruvate, NADPH, and H+....

: thiomorpholine-carboxylate dehydrogenase
Thiomorpholine-carboxylate dehydrogenase
In enzymology, a thiomorpholine-carboxylate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are thiomorpholine 3-carboxylate, NAD+, and NADP+, whereas its 4 products are 3,4-dehydro-thiomorpholine-3-carboxylate, NADH, NADPH, and H+.This enzyme belongs...

: b-alanopine dehydrogenase: 1,2-dehydroreticulinium reductase (NADPH)
1,2-dehydroreticulinium reductase (NADPH)
In enzymology, a 1,2-dehydroreticulinium reductase is an enzyme that catalyzes the chemical reaction-reticuline + NADP+ \rightleftharpoons 1,2-dehydroreticulinium + NADPH + H+...

: opine dehydrogenase: FMN reductase
FMN reductase
In enzymology, an FMN reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are FMNH2, NAD+, and NADP+, whereas its 4 products are FMN, NADH, NADPH, and H+....

: flavin reductase
Flavin reductase
In enzymology, a flavin reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are reduced riboflavin and NADP+, whereas its 3 products are riboflavin, NADPH, and H+....

: berberine reductase
Berberine reductase
In enzymology, a berberine reductase is an enzyme that catalyzes the chemical reaction-canadine + 2 NADP+ \rightleftharpoons berberine + 2 NADPH + H+...

: vomilenine reductase
Vomilenine reductase
In enzymology, a vomilenine reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1,2-dihydrovomilenine and NADP+, whereas its 3 products are vomilenine, NADPH, and H+....

: pteridine reductase
Pteridine reductase
In enzymology, a pteridine reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5,6,7,8-tetrahydrobiopterin and NADP+, whereas its 3 products are biopterin, NADPH, and H+....

: 6,7-dihydropteridine reductase
6,7-dihydropteridine reductase
In enzymology, a 6,7-dihydropteridine reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 5,6,7,8-tetrahydropteridine, NAD+, and NADP+, whereas its 4 products are 6,7-dihydropteridine, NADH, NADPH, and H+....


EC 1.5.3 With oxygen
Oxygen
Oxygen is the element with atomic number 8 and represented by the symbol O. Its name derives from the Greek roots ὀξύς and -γενής , because at the time of naming, it was mistakenly thought that all acids required oxygen in their composition...

 as acceptor

: sarcosine oxidase
Sarcosine oxidase
Sarcosine oxidase is an enzyme that catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, 5,10-CH2-tetrahydrofolate in a reaction requiring H4-tetrahydrofolate and oxygen....

: N-methyl-L-amino-acid oxidase
N-methyl-L-amino-acid oxidase
In enzymology, a N-methyl-L-amino-acid oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N-methyl-L-amino acid, H2O, and O2, whereas its 3 products are L-amino acid, formaldehyde, and H2O2....

: deleted: N6-methyl-lysine oxidase
N6-methyl-lysine oxidase
In enzymology, a N6-methyl-lysine oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N6-methyl-L-lysine, H2O, and O2, whereas its 3 products are L-lysine, formaldehyde, and H2O2....

: (S)-6-hydroxynicotine oxidase
(S)-6-hydroxynicotine oxidase
In enzymology, a -6-hydroxynicotine oxidase is an enzyme that catalyzes the chemical reaction-6-hydroxynicotine + H2O + O2 \rightleftharpoons 1--4-butan-1-one + H2O2...

: (R)-6-hydroxynicotine oxidase
(R)-6-hydroxynicotine oxidase
In enzymology, a -6-hydroxynicotine oxidase is an enzyme that catalyzes the chemical reaction-6-hydroxynicotine + H2O + O2 \rightleftharpoons 1--4-butan-1-one + H2O2...

: L-pipecolate oxidase
L-pipecolate oxidase
In enzymology, a L-pipecolate oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-pipecolate and O2, whereas its two products are 2,3,4,5-tetrahydropyridine-2-carboxylate and H2O2....

: deleted, included in *EC 1.3.3.8: now *EC 1.21.3.3: dimethylglycine oxidase
Dimethylglycine oxidase
In enzymology, a dimethylglycine oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N,N-dimethylglycine, H2O, and O2, whereas its 3 products are sarcosine, formaldehyde, and H2O2....

: polyamine oxidase
Polyamine oxidase
In enzymology, a polyamine oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N1-acetylspermine, O2, and H2O, whereas its 3 products are N1-acetylspermidine, 3-aminopropanal, and H2O2....

: dihydrobenzophenanthridine oxidase
Dihydrobenzophenanthridine oxidase
Dihydrobenzophenanthridine oxidase is an enzyme. In the IUBMB Enzyme Nomenclature, Dihydrobenzophenanthridine oxidase is .Dihydrobenzophenanthridine oxidase/EC 1.5.3.12 produces oxidized forms of benzophenanthridine alkaloids:...


EC 1.5.5 With a quinone
Quinone
A quinone is a class of organic compounds that are formally "derived from aromatic compounds [such as benzene or naphthalene] by conversion of an even number of –CH= groups into –C– groups with any necessary rearrangement of double bonds," resulting in "a fully conjugated cyclic dione structure."...

 or similar compound as acceptor

: electron-transferring-flavoprotein dehydrogenase
Electron-transferring-flavoprotein dehydrogenase
Electron-transferring-flavoprotein dehydrogenase is an enzyme that transfers electrons from electron-transferring flavoprotein in the mitochondrial matrix, to the ubiquinone pool in the inner mitochondrial membrane. It is part of the electron transport chain...


EC 1.5.7 With an iron-sulfur protein
Iron-sulfur protein
Iron-sulfur proteins are proteins characterized by the presence of iron-sulfur clusters containing sulfide-linked di-, tri-, and tetrairon centers in variable oxidation states...

 as acceptor

: methylenetetrahydrofolate reductase (ferredoxin)
Methylenetetrahydrofolate reductase (ferredoxin)
In enzymology, a methylenetetrahydrofolate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5-methyltetrahydrofolate and oxidized ferredoxin, whereas its 3 products are 5,10-methylenetetrahydrofolate, reduced ferredoxin, and H+.This enzyme...


EC 1.5.8 With a flavin as acceptor

: dimethylamine dehydrogenase
Dimethylamine dehydrogenase
In enzymology, a dimethylamine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are dimethylamine, H2O, and electron-transferring flavoprotein, whereas its 3 products are methylamine, formaldehyde, and reduced electron-transferring flavoprotein.This...

: trimethylamine dehydrogenase
Trimethylamine dehydrogenase
In enzymology, a trimethylamine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are trimethylamine, H2O, and electron-transferring flavoprotein, whereas its 3 products are dimethylamine, formaldehyde, and reduced electron-transferring...


EC 1.5.99 With other acceptors

: sarcosine dehydrogenase
Sarcosine dehydrogenase
In enzymology, a sarcosine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are sarcosine, acceptor, and H2O, whereas its 3 products are glycine, formaldehyde, and reduced acceptor....

: dimethylglycine dehydrogenase
Dimethylglycine dehydrogenase
In enzymology, a dimethylglycine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N,N-dimethylglycine, acceptor, and H2O, whereas its 3 products are sarcosine, formaldehyde, and reduced acceptor....

: L-pipecolate dehydrogenase
L-pipecolate dehydrogenase
In enzymology, a L-pipecolate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-pipecolate and acceptor, whereas its two products are 2,3,4,5-tetrahydropyridine-2-carboxylate and reduced acceptor....

: nicotine dehydrogenase
Nicotine dehydrogenase
In enzymology, a nicotine dehydrogenase is an enzyme that catalyzes the chemical reaction-nicotine + acceptor + H2O \rightleftharpoons -6-hydroxynicotine + reduced acceptor...

: methylglutamate dehydrogenase
Methylglutamate dehydrogenase
In enzymology, a methylglutamate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N-methyl-L-glutamate, acceptor, and H2O, whereas its 3 products are L-glutamate, formaldehyde, and reduced acceptor....

: spermidine dehydrogenase
Spermidine dehydrogenase
In enzymology, a spermidine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are spermidine, acceptor, and H2O, whereas its 3 products are propane-1,3-diamine, 4-aminobutanal, and reduced acceptor....

: now *EC 1.5.8.2: proline dehydrogenase
Proline dehydrogenase
In enzymology, a proline dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-proline and acceptor, whereas its two products are -1-pyrroline-5-carboxylate and reduced acceptor....

: methylenetetrahydromethanopterin dehydrogenase
Methylenetetrahydromethanopterin dehydrogenase
In enzymology, a methylenetetrahydromethanopterin dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5,10-methylenetetrahydromethanopterin and coenzyme F420, whereas its two products are 5,10-methenyltetrahydromethanopterin and reduced...

: now *EC 1.5.8.1: 5,10-methylenetetrahydromethanopterin reductase
5,10-methylenetetrahydromethanopterin reductase
In enzymology, a 5,10-methylenetetrahydromethanopterin reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5-methyltetrahydromethanopterin and coenzyme F420, whereas its two products are 5,10-methylenetetrahydromethanopterin and reduced coenzyme...

: cytokinin dehydrogenase
Cytokinin dehydrogenase
In enzymology, a cytokinin dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N6-dimethylallyladenine, acceptor, and H2O, whereas its 3 products are adenine, 3-methylbut-2-enal, and reduced acceptor....


EC 1.6.1 With NAD or NADP as acceptor

: NAD(P)+ transhydrogenase (B-specific)
NAD(P)+ transhydrogenase (B-specific)
In enzymology, a NAD+ transhydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are NADPH and NAD+, whereas its two products are NADP+ and NADH....

: NAD(P)+ transhydrogenase (AB-specific)
NAD(P)+ transhydrogenase (AB-specific)
In enzymology, a NAD+ transhydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are NADPH and NAD+, whereas its two products are NADP+ and NADH....


EC 1.6.2 With a heme protein as acceptor

: now EC 1.6.99.3: cytochrome-b5 reductase: deleted: NADPH—hemoprotein reductase: NADPH—cytochrome-c2 reductase: leghemoglobin reductase
Leghemoglobin reductase
In enzymology, a leghemoglobin reductase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are NADH, NADPH, H+, and ferrileghemoglobin, whereas its 3 products are NAD+, NADP+, and ferroleghemoglobin....


EC 1.6.4 With a disulfide as acceptor

: now EC 1.8.1.6: now EC 1.8.1.7: now EC 1.8.1.4: now EC 1.8.1.8: now EC 1.8.1.9: now EC 1.8.1.10: now EC 1.8.1.11: now EC 1.8.1.12: now EC 1.8.1.13: now EC 1.8.1.14

EC 1.6.5 With a quinone or similar compound as acceptor

: deleted: NAD(P)H dehydrogenase (quinone)
NAD(P)H dehydrogenase (quinone)
In enzymology, a NADH dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are NADH, NADPH, H+, and quinone, whereas its 3 products are NAD+, NADP+, and hydroquinone....

: NADH dehydrogenase (ubiquinone): monodehydroascorbate reductase (NADH)
Monodehydroascorbate reductase (NADH)
In enzymology, a monodehydroascorbate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NADH, H+, and monodehydroascorbate, whereas its two products are NAD+ and ascorbate....

: NADPH:quinone reductase
NADPH:quinone reductase
In enzymology, a NADPH:quinone reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NADPH, H+, and quinone, whereas its two products are NADP+ and semiquinone....

: p-benzoquinone reductase (NADPH)
P-benzoquinone reductase (NADPH)
In enzymology, a p-benzoquinone reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NADPH, H+, and p-benzoquinone, whereas its two products are NADP+ and hydroquinone....

: 2-hydroxy-1,4-benzoquinone reductase
2-hydroxy-1,4-benzoquinone reductase
In enzymology, a 2-hydroxy-1,4-benzoquinone reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-hydroxy-1,4-benzoquinone, NADH, and H+, whereas its two products are 1,2,4-trihydroxybenzene and NAD+....


EC 1.6.6 With a nitrogenous group as acceptor

: now *EC 1.7.1.1: now *EC 1.7.1.2: now *EC 1.7.1.3: now *EC 1.7.1.4: now *EC 1.7.99.3: now *EC 1.7.1.5: now *EC 1.7.1.6: now *EC 1.7.1.7: trimethylamine-N-oxide reductase
Trimethylamine-N-oxide reductase
In enzymology, a trimethylamine-N-oxide reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NADH, H+, and trimethylamine N-oxide, whereas its 3 products are NAD+, trimethylamine, and H2O....

: now *EC 1.7.1.9: now *EC 1.7.1.10: now *EC 1.7.1.11: now *EC 1.7.1.12

EC 1.6.99 With other acceptors

: NADPH dehydrogenase
NADPH dehydrogenase
In enzymology, a NADPH dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NADPH, H+, and acceptor, whereas its two products are NADP+ and reduced acceptor....

: now *EC 1.6.5.2: NADH dehydrogenase
NADH dehydrogenase
NADH dehydrogenase is an enzyme located in the inner mitochondrial membrane that catalyzes the transfer of electrons from NADH to coenzyme Q...

: now *EC 1.18.1.2: NADH dehydrogenase (quinone)
NADH dehydrogenase (quinone)
In enzymology, a NADH dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NADH, H+, and acceptor, whereas its two products are NAD+ and reduced acceptor....

: NADPH dehydrogenase (quinone)
NADPH dehydrogenase (quinone)
In enzymology, a NADPH dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NADPH, H+, and acceptor, whereas its two products are NADP+ and reduced acceptor....

: now *EC 1.5.1.34: now *EC 1.16.1.3: now *EC 1.16.1.4: deleted, included in *EC 1.6.99.7: now *EC 1.16.1.5: now *EC 1.16.1.6: now *EC 1.16.1.7

EC 1.7.1 With NAD+ or NADP+ as acceptor

: nitrate reductase (NADH): nitrate reductase (NAD(P)H): nitrate reductase (NADPH): nitrite reductase (NAD(P)H)
Nitrite reductase (NAD(P)H)
In enzymology, a nitrite reductase [NADH] is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are ammonium hydroxide, NAD+, NADP+, and H2O, whereas its 4 products are nitrite, NADH, NADPH, and H+....

: hyponitrite reductase
Hyponitrite reductase
In enzymology, a hyponitrite reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are hydroxylamine and NAD+, whereas its 3 products are hyponitrous acid, NADH, and H+....

: azobenzene reductase
Azobenzene reductase
In enzymology, an azobenzene reductase also known as azoreductase is an enzyme that catalyzes the chemical reaction:The 3 substrates of this enzyme are N,N-dimethyl-1,4-phenylenediamine, aniline, and NADP+, whereas its 3 products are 4-azobenzene, NADPH, and H+.This enzyme belongs to the family of...

: GMP reductase
GMP reductase
GMP reductase is an enzyme that converts GMP to IMP. In melanocytic cells, GMP reductase gene expression may be regulated by MITF.-External links:...

: deleted entry: nitroquinoline-N-oxide reductase
Nitroquinoline-N-oxide reductase
In enzymology, a nitroquinoline-N-oxide reductase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 4-hydroxyaminoquinoline N-oxide, NAD+, NADP+, and H2O, whereas its 4 products are 4-nitroquinoline N-oxide, NADH, NADPH, and H+.This enzyme belongs to the family...

: hydroxylamine reductase (NADH)
Hydroxylamine reductase (NADH)
In enzymology, a hydroxylamine reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NH3, NAD+, and H2O, whereas its 3 products are hydroxylamine, NADH, and H+....

: 4-(dimethylamino)phenylazoxybenzene reductase
4-(dimethylamino)phenylazoxybenzene reductase
In enzymology, a 4-phenylazoxybenzene reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 4-phenylazobenzene and NADP+, whereas its 3 products are 4-phenylazoxybenzene, NADPH, and H+.This enzyme belongs to the family of oxidoreductases,...

: N-hydroxy-2-acetamidofluorene reductase
N-hydroxy-2-acetamidofluorene reductase
In enzymology, a N-hydroxy-2-acetamidofluorene reductase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2-acetamidofluorene, NAD+, NADP+, and H2O, whereas its 4 products are N-hydroxy-2-acetamidofluorene, NADH, NADPH, and H+.This enzyme belongs to the family...


EC 1.7.2 With a cytochrome as acceptor

: nitrite reductase (NO-forming)
Nitrite reductase (NO-forming)
In enzymology, a nitrite reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are nitric oxide, H2O, and ferricytochrome c, whereas its 3 products are nitrite, ferrocytochrome c, and H+....

: nitrite reductase (cytochrome; ammonia-forming): trimethylamine-N-oxide reductase (cytochrome c)
Trimethylamine-N-oxide reductase (cytochrome c)
In enzymology, a trimethylamine-N-oxide reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are trimethylamine, -subunit, and H2O, whereas its 3 products are trimethylamine N-oxide, -subunit, and H+.This enzyme belongs to the family of oxidoreductases,...


EC 1.7.3 With oxygen as acceptor

: nitroalkane oxidase
Nitroalkane oxidase
In enzymology, a nitroalkane oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are nitroalkane, H2O, and O2, whereas its 4 products are aldehyde, ketone, nitrite, and H2O2....

: acetylindoxyl oxidase
Acetylindoxyl oxidase
In enzymology, an acetylindoxyl oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are N-acetylindoxyl and O2, whereas its product is N-acetylisatin....

: urate oxidase
Urate oxidase
The enzyme urate oxidase , or uricase or factor-independent urate hydroxylase, catalyzes the oxidation of uric acid to 5-hydroxyisourate:-Structure:...

: hydroxylamine oxidase
Hydroxylamine oxidase
In enzymology, a hydroxylamine oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are hydroxylamine and O2, whereas its two products are nitrite and H2O....

: 3-aci-nitropropanoate oxidase
3-aci-nitropropanoate oxidase
In enzymology, a 3-aci-nitropropanoate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 3-aci-nitropropanoate, O2, and H2O, whereas its 3 products are 3-oxopropanoate, nitrite, and H2O2....


EC 1.7.7 With an iron-sulfur protein as acceptor

: ferredoxin—nitrite reductase: ferredoxin—nitrate reductase

EC 1.7.99 With other acceptors

: hydroxylamine reductase
Hydroxylamine reductase
In enzymology, a hydroxylamine reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NH3, H2O, and acceptor, whereas its two products are hydroxylamine and reduced acceptor....

: deleted: included with *EC 1.7.2.1: nitrate reductase
Nitrate reductase
Nitrate reductases are molybdoenzymes that reduce nitrate to nitrite .* Eukaryotic nitrate reductases are part of the sulfite oxidase family of molybdoenzymes....

: deleted, now included with *EC 1.5.1.20: nitrous-oxide reductase
Nitrous-oxide reductase
In enzymology, a nitrous oxide reductase is an enzyme that catalyzes the chemical reactionThe three substrates of this enzyme are nitrous oxide and reduced cytochrome c; its three products are nitrogen, H2O, and oxidized cytochrome c...

: nitric-oxide reductase
Nitric-oxide reductase
In enzymology, a nitric-oxide reductase is an enzyme that catalyzes the chemical reactionThe 2 substrates of this enzyme are nitric oxide and electron donor, whereas its three products are nitrous oxide, oxidized electron donor/acceptor, and H2O....

: hydroxylamine oxidoreductase

EC 1.8.1 With NAD or NADP as acceptor

: deleted: sulfite reductase (NADPH): hypotaurine dehydrogenase
Hypotaurine dehydrogenase
In enzymology, a hypotaurine dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are hypotaurine, H2O, and NAD+, whereas its 3 products are taurine, NADH, and H+....

: dihydrolipoyl dehydrogenase: 2-oxopropyl-CoM reductase (carboxylating)
2-oxopropyl-CoM reductase (carboxylating)
In enzymology, a 2-oxopropyl-CoM reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-mercaptoethanesulfonate, acetoacetate, and NADP+, whereas its 3 products are 2-ethanesulfonate, CO2, and NADPH.This enzyme belongs to the family of oxidoreductases,...

: cystine reductase
Cystine reductase
In enzymology, a cystine reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-cysteine and NAD+, whereas its 3 products are L-cystine, NADH, and H+....

: glutathione-disulfide reductase: protein-disulfide reductase
Protein-disulfide reductase
In enzymology, a protein-disulfide reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are protein dithiol, NAD+, and NADP+, whereas its 4 products are protein disulfide, NADH, NADPH, and H+....

: thioredoxin-disulfide reductase: CoA-glutathione reductase
CoA-glutathione reductase
In enzymology, a CoA-glutathione reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are CoA, glutathione, and NADP+, whereas its 3 products are CoA-glutathione, NADPH, and H+....

: asparagusate reductase
Asparagusate reductase
In enzymology, an asparagusate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-mercapto-2-mercaptomethylpropanoate and NAD+, whereas its 3 products are asparagusate, NADH, and H+....

: trypanothione-disulfide reductase
Trypanothione-disulfide reductase
In enzymology, a trypanothione-disulfide reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are trypanothione and NADP+, whereas its 3 products are trypanothione disulfide, NADPH, and H+....

: bis-g-glutamylcystine reductase: CoA-disulfide reductase
CoA-disulfide reductase
In enzymology, a CoA-disulfide reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are CoA, NAD+, and NADP+, whereas its 4 products are CoA-disulfide, NADH, NADPH, and H+....

: mycothione reductase
Mycothione reductase
In enzymology, a mycothione reductase is an enzyme that catalyzes the chemical reactionin M. tuberculosis and other actinomycetes.The 2 substrates of this enzyme are mycothiol and NADPH, whereas 2 molecules of mycothione and NADP+ are formed as products.This enzyme belongs to the family of...


EC 1.8.2 With a cytochrome as acceptor

: sulfite dehydrogenase
Sulfite dehydrogenase
In enzymology, a sulfite dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are sulfite, ferricytochrome c, and H2O, whereas its 3 products are sulfate, ferrocytochrome c, and H+....

: thiosulfate dehydrogenase
Thiosulfate dehydrogenase
Thiosulfate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are thiosulfate and ferricytochrome c, whereas its two products are tetrathionate and ferrocytochrome c....


EC 1.8.3 With oxygen as acceptor

: sulfite oxidase
Sulfite oxidase
Sulfite oxidase is an enzyme in the mitochondria of all eukaryotes. It oxidizes sulfite to sulfate and, via cytochrome c, transfers the electrons produced to the electron transport chain, allowing generation of ATP in oxidative phosphorylation...

: thiol oxidase
Thiol oxidase
In enzymology, a thiol oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are R'CSH and O2, whereas its two products are R'CS-SCR' and H2O....

: glutathione oxidase
Glutathione oxidase
In enzymology, a glutathione oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glutathione and O2, whereas its two products are glutathione disulfide and H2O2....

: methanethiol oxidase
Methanethiol oxidase
In enzymology, a methanethiol oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are methanethiol, O2, and H2O, whereas its 3 products are formaldehyde, hydrogen sulfide, and H2O2....

: prenylcysteine oxidase
Prenylcysteine oxidase
In enzymology, a prenylcysteine oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are S-prenyl-L-cysteine, O2, and H2O, whereas its 3 products are prenal, L-cysteine, and H2O2....


EC 1.8.4 With a disulfide as acceptor

: glutathione—homocystine transhydrogenase: protein-disulfide reductase (glutathione)
Protein-disulfide reductase (glutathione)
In enzymology, a protein-disulfide reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glutathione and protein disulfide, whereas its two products are glutathione disulfide and protein dithiol.This enzyme belongs to the family of oxidoreductases,...

: glutathione—CoA-glutathione transhydrogenase: glutathione—cystine transhydrogenase: methionine-S-oxide reductase: protein-methionine-S-oxide reductase: enzyme-thiol transhydrogenase (glutathione-disulfide)
Enzyme-thiol transhydrogenase (glutathione-disulfide)
In enzymology, an enzyme-thiol transhydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are xanthine dehydrogenase and glutathione disulfide, whereas its two products are xanthine oxidase and glutathione.This enzyme belongs to the family of...

: phosphoadenylyl-sulfate reductase (thioredoxin)
Phosphoadenylyl-sulfate reductase (thioredoxin)
In enzymology, a phosphoadenylyl-sulfate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are adenosine 3',5'-bisphosphate, sulfite, and thioredoxin disulfide, whereas its two products are 3'-phosphoadenylyl sulfate and thioredoxin.This enzyme belongs to...

: adenylyl-sulfate reductase (glutathione)
Adenylyl-sulfate reductase (glutathione)
In enzymology, an adenylyl-sulfate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are AMP, sulfite, and glutathione disulfide, whereas its two products are adenylyl sulfate and glutathione....

: adenylyl-sulfate reductase (thioredoxin)
Adenylyl-sulfate reductase (thioredoxin)
In enzymology, an adenylyl-sulfate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are AMP, sulfite, and thioredoxin disulfide, whereas its two products are 5'-adenylyl sulfate and thioredoxin....


EC 1.8.5 With a quinone or similar compound as acceptor

: glutathione dehydrogenase (ascorbate)
Glutathione dehydrogenase (ascorbate)
In enzymology, a glutathione dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glutathione and dehydroascorbate, whereas its two products are glutathione disulfide and ascorbate....

: thiosulfate dehydrogenase (quinone)
Thiosulfate dehydrogenase (quinone)
In enzymology, a thiosulfate dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are thiosulfate and 6-decylubiquinone, whereas its two products are tetrathionate and 6-decylubiquinol....


EC 1.8.99 With other acceptors

: sulfite reductase
Sulfite reductase
Sulfite reductases are important enzymes in the process of sulfur metabolism. They catalyze the reduction of sulfite to hydrogen sulfide and water. Electrons for the reaction are provided by a dissociable molecule of either NADPH, bound flavins, or ferredoxins.Sulfite reductases belong to the...

: adenylyl-sulfate reductase
Adenylyl-sulfate reductase
In enzymology, an adenylyl-sulfate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are AMP, sulfite, and acceptor, whereas its two products are adenylyl sulfate and reduced acceptor....

: hydrogensulfite reductase
Hydrogensulfite reductase
In enzymology, a hydrogensulfite reductase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are trithionate, acceptor, H2O, and OH-, whereas its two products are bisulfite and reduced acceptor....

: now EC 1.8.4.8

EC 1.10.2 With a cytochrome as acceptor

: L-ascorbate—cytochrome-b5 reductase: ubiquinol—cytochrome-c reductase

EC 1.10.3 With oxygen as acceptor

: catechol oxidase
Catechol oxidase
Catechol oxidase is an enzyme that catalyses the oxidation of phenols such as catechol. Catechol oxidase is a copper-containing enzyme whose activity is similar to that of tyrosinase, a related class of copper oxidases....

: laccase
Laccase
Laccases are copper-containing oxidase enzymes that are found in many plants, fungi, and microorganisms. The copper is bound in several sites; Type 1, Type 2, and/or Type 3. The ensemble of types 2 and 3 copper is called a trinuclear cluster . Type 1 copper is available to action of solvents,...

: L-ascorbate oxidase
L-ascorbate oxidase
In enzymology, a L-ascorbate oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-ascorbate and O2, whereas its two products are dehydroascorbate and H2O....

: o-aminophenol oxidase: 3-hydroxyanthranilate oxidase
3-hydroxyanthranilate oxidase
In enzymology, a 3-hydroxyanthranilate oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-hydroxyanthranilate and O2, whereas its two products are 6-imino-5-oxocyclohexa-1,3-dienecarboxylate and H2O2....

: rifamycin-B oxidase
Rifamycin-B oxidase
In enzymology, a rifamycin-B oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are rifamycin B and O2, whereas its two products are rifamycin O and H2O2....

: now *EC 1.21.3.4: now *EC 1.21.3.5

EC 1.10.99 With other acceptors

: plastoquinol—plastocyanin reductase: ribosyldihydronicotinamide dehydrogenase (quinone)
Ribosyldihydronicotinamide dehydrogenase (quinone)
In enzymology, a ribosyldihydronicotinamide dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1--1,4-dihydronicotinamide and quinone, whereas its two products are 1-nicotinamide and hydroquinone.This enzyme belongs to the family of...

: violaxanthin de-epoxidase

EC 1.11.1 Peroxidases

: NADH peroxidase
NADH peroxidase
In enzymology, a NADH peroxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NADH, H+, and H2O2, whereas its two products are NAD+ and H2O....

: NADPH peroxidase
NADPH peroxidase
In enzymology, a NADPH peroxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are NADPH, H+, and H2O2, whereas its two products are NADP+ and H2O....

: fatty-acid peroxidase
Fatty-acid peroxidase
In enzymology, a fatty-acid peroxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are palmitate and H2O2, whereas its 3 products are pentadecanal, CO2, and H2O....

: now *EC 1.13.11.11: cytochrome-c peroxidase: catalase
Catalase
Catalase is a common enzyme found in nearly all living organisms that are exposed to oxygen, where it catalyzes the decomposition of hydrogen peroxide to water and oxygen...

: peroxidase
Peroxidase
Peroxidases are a large family of enzymes that typically catalyze a reaction of the form:For many of these enzymes the optimal substrate is hydrogen peroxide, but others are more active with organic hydroperoxides such as lipid peroxides...

: iodide peroxidase: glutathione peroxidase
Glutathione peroxidase
Glutathione peroxidase is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage...

: chloride peroxidase
Chloride peroxidase
In enzymology, a chloride peroxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are RH, Cl−, and H2O2, whereas its two products are RCl and H2O....

: L-ascorbate peroxidase
L-ascorbate peroxidase
In enzymology, a L-ascorbate peroxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-ascorbate and H2O2, whereas its two products are dehydroascorbate and H2O....

: phospholipid-hydroperoxide glutathione peroxidase
Phospholipid-hydroperoxide glutathione peroxidase
In enzymology, a phospholipid-hydroperoxide glutathione peroxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are glutathione and lipid hydroperoxide, whereas its 3 products are glutathione disulfide, lipid, and H2O.This enzyme belongs to the family of...

: manganese peroxidase
Manganese peroxidase
In enzymology, a manganese peroxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are Mn, H+, and H2O2, whereas its two products are Mn and H2O....

: diarylpropane peroxidase: peroxiredoxin
Peroxiredoxin
Peroxiredoxins are a ubiquitous family of antioxidant enzymes that also control cytokine-induced peroxide levels and thereby mediate signal transduction in mammalian cells.- Classification :...


EC 1.12.1 With NAD or NADP as acceptor

: now EC 1.18.99.1: hydrogen dehydrogenase
Hydrogen dehydrogenase
In enzymology, a hydrogen dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are H2 and NAD+, whereas its two products are H+ and NADH....

: hydrogen dehydrogenase (NADP+)
Hydrogen dehydrogenase (NADP+)
In enzymology, a hydrogen dehydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are H2 and NADP+, whereas its two products are H+ and NADPH....


EC 1.12.98 With other known acceptors

: coenzyme F420 hydrogenase
Coenzyme F420 hydrogenase
In enzymology, a coenzyme F420 hydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are H2 and coenzyme F420, whereas its product is reduced coenzyme F420....

: 5,10-methenyltetrahydromethanopterin hydrogenase
5,10-methenyltetrahydromethanopterin hydrogenase
The 5,10-methenyltetrahydromethanopterin hydrogenase , the so-called iron-sulfur cluster-free hydrogenase, is an enzyme found in methanogenic archea such as Methanothermacter marburgensis. It was discovered and first characterized by the Thauer group at the Max Planck Institute in Marburg...

: Methanosarcina-phenazine hydrogenase
Methanosarcina-phenazine hydrogenase
In enzymology, a Methanosarcina-phenazine hydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are H2 and 2-phenazine, whereas its product is 2-dihydropentaprenyloxyphenazine....


EC 1.12.99 With other acceptors

: now *EC 1.12.98.1: deleted, composed of *EC 1.12.98.3 and *EC 1.8.98.1: now *EC 1.12.5.1: now *EC 1.12.98.2: identical to *EC 1.13.11.47: hydrogenase (acceptor)
Hydrogenase (acceptor)
In enzymology, a hydrogenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are H2 and A, whereas its product is AH2....


EC 1.13.1 (transferred to EC 1.13.11)

: now *EC 1.13.11.1: now *EC 1.13.11.2: now *EC 1.13.11.3: now *EC 1.13.11.4: now *EC 1.13.11.5: now *EC 1.13.11.6: now *EC 1.13.11.7: now *EC 1.13.11.8: now *EC 1.13.11.9: now *EC 1.13.11.10: now *EC 1.13.99.1: now *EC 1.13.11.11: now *EC 1.13.11.12

EC 1.13.11 With incorporation of two atoms of oxygen

: catechol 1,2-dioxygenase: catechol 2,3-dioxygenase: protocatechuate 3,4-dioxygenase
Protocatechuate 3,4-dioxygenase
In enzymology, a protocatechuate 3,4-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3,4-dihydroxybenzoate and O2, whereas its product is 3-carboxy-cis,cis-muconate....

: gentisate 1,2-dioxygenase
Gentisate 1,2-dioxygenase
In enzymology, a gentisate 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2,5-dihydroxybenzoate and O2, whereas its product is maleylpyruvate....

: homogentisate 1,2-dioxygenase
Homogentisate 1,2-dioxygenase
Homogentisate 1,2-dioxygenase is an enzyme, which catalyzes the conversion of homogentisate to 4-maleylacetoacetate. Homogentisate 1,2-dioxygenase or HGD is involved in the catabolism of aromatic rings, more specifically in the breakdown of the amino acids tyrosine and phenylalanine...

: 3-hydroxyanthranilate 3,4-dioxygenase
3-hydroxyanthranilate 3,4-dioxygenase
In enzymology, a 3-hydroxyanthranilate 3,4-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-hydroxyanthranilate and O2, whereas its product is 2-amino-3-carboxymuconate semialdehyde....

: deleted: protocatechuate 4,5-dioxygenase
Protocatechuate 4,5-dioxygenase
In enzymology, a protocatechuate 4,5-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are protocatechuate and O2, whereas its product is 4-carboxy-2-hydroxymuconate semialdehyde....

: 2,5-dihydroxypyridine 5,6-dioxygenase
2,5-dihydroxypyridine 5,6-dioxygenase
In enzymology, a 2,5-dihydroxypyridine 5,6-dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2,5-dihydroxypyridine, O2, and H2O, whereas its two products are maleamate and formate....

: 7,8-dihydroxykynurenate 8,8a-dioxygenase
7,8-dihydroxykynurenate 8,8a-dioxygenase
In enzymology, a 7,8-dihydroxykynurenate 8,8a-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 7,8-dihydroxykynurenate and O2, whereas its product is 5--4,6-dihydroxypyridine-2-carboxylate.This enzyme belongs to the family of oxidoreductases,...

: tryptophan 2,3-dioxygenase
Tryptophan 2,3-dioxygenase
In enzymology, a tryptophan 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-tryptophan and O2, whereas its product is N-formyl-L-kynurenine....

: lipoxygenase
Lipoxygenase
Lipoxygenases are a family of iron-containing enzymes that catalyse the dioxygenation of polyunsaturated fatty acids in lipids containing a cis,cis-1,4- pentadiene structure. It catalyses the following reaction:...

: ascorbate 2,3-dioxygenase
Ascorbate 2,3-dioxygenase
In enzymology, an ascorbate 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are ascorbate, O2, and H2O, whereas its two products are oxalate and threonate....

: 2,3-dihydroxybenzoate 3,4-dioxygenase
2,3-dihydroxybenzoate 3,4-dioxygenase
In enzymology, a 2,3-dihydroxybenzoate 3,4-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2,3-dihydroxybenzoate and O2, whereas its product is 3-carboxy-2-hydroxymuconate semialdehyde....

: 3,4-dihydroxyphenylacetate 2,3-dioxygenase
3,4-dihydroxyphenylacetate 2,3-dioxygenase
In enzymology, a 3,4-dihydroxyphenylacetate 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3,4-dihydroxyphenylacetate and O2, whereas its product is 2-hydroxy-5-carboxymethylmuconate semialdehyde....

: 3-carboxyethylcatechol 2,3-dioxygenase
3-carboxyethylcatechol 2,3-dioxygenase
In enzymology, a 3-carboxyethylcatechol 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-propanoate and O2, whereas its product is 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate....

: indole 2,3-dioxygenase
Indole 2,3-dioxygenase
In enzymology, an indole 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are indole and O2, whereas its product is 2-formylaminobenzaldehyde....

: sulfur dioxygenase: cysteamine dioxygenase
Cysteamine dioxygenase
In enzymology, a cysteamine dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-aminoethanethiol and O2, whereas its product is hypotaurine....

: cysteine dioxygenase
Cysteine dioxygenase
Cysteine dioxygenase ) is a mammalian non-heme iron enzyme that catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen....

: now *EC 1.14.99.36: caffeate 3,4-dioxygenase
Caffeate 3,4-dioxygenase
In enzymology, a caffeate 3,4-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3,4-dihydroxy-trans-cinnamate and O2, whereas its product is 3--cis,cis-muconate....

: 2,3-dihydroxyindole 2,3-dioxygenase
2,3-dihydroxyindole 2,3-dioxygenase
In enzymology, a 2,3-dihydroxyindole 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2,3-dihydroxyindole and O2, whereas its two products are anthranilate and CO2....

: quercetin 2,3-dioxygenase
Quercetin 2,3-dioxygenase
In enzymology, a quercetin 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are quercetin and O2, whereas its 3 products are 2--4,6-dihydroxybenzoate, CO, and H+....

: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase
3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase
In enzymology, a 3,4-dihydroxy-9,10-secoandrosta-1,3,5-triene-9,17-dione 4,5-dioxygenase is an enzyme that catalyzes the chemical reaction...

: peptide-tryptophan 2,3-dioxygenase
Peptide-tryptophan 2,3-dioxygenase
In enzymology, a peptide-tryptophan 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are peptide tryptophan and O2, whereas its product is peptide formylkynurenine....

: 4-hydroxyphenylpyruvate dioxygenase
4-Hydroxyphenylpyruvate dioxygenase
4-Hydroxyphenylpyruvate dioxygenase HPPD is an Fe-containing enzyme, that catalyzes the second reaction in the catabolism of tyrosine - the conversion of 4-hydroxyphenylpyruvate to homogentisate.-Function:...

: 2,3-dihydroxybenzoate 2,3-dioxygenase
2,3-dihydroxybenzoate 2,3-dioxygenase
In enzymology, a 2,3-dihydroxybenzoate 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2,3-dihydroxybenzoate and O2, whereas its product is 2-carboxy-cis,cis-muconate....

: stizolobate synthase
Stizolobate synthase
In enzymology, a stizolobate synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3,4-dihydroxy-L-phenylalanine and O2, whereas its product is 4--2-hydroxy-cis,cis-muconate 6-semialdehyde....

: stizolobinate synthase
Stizolobinate synthase
In enzymology, a stizolobinate synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3,4-dihydroxy-L-phenylalanine and O2, whereas its product is 5--2-hydroxy-cis,cis-muconate 6-semialdehyde....

: arachidonate 12-lipoxygenase
Arachidonate 12-lipoxygenase
In enzymology, an arachidonate 12-lipoxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are arachidonate and O2, whereas its product is --12-hydroperoxyicosa-5,8,10,14-tetraenoate....

: 2-nitropropane dioxygenase
2-nitropropane dioxygenase
In enzymology, a 2-nitropropane dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-nitropropane and O2, whereas its two products are acetone and nitrite....

: arachidonate 15-lipoxygenase
Arachidonate 15-lipoxygenase
In enzymology, an arachidonate 15-lipoxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are arachidonate and O2, whereas its product is --15-hydroperoxyicosa-5,8,11,13-tetraenoate....

: arachidonate 5-lipoxygenase
Arachidonate 5-lipoxygenase
Arachidonate 5-lipoxygenase also known as 5-lipoxygenase or 5-LO is an enzyme that in humans is encoded by the ALOX5 gene. Arachidonate 5-lipoxygenase is a member of the lipoxygenase family of enzymes...

: pyrogallol 1,2-oxygenase
Pyrogallol 1,2-oxygenase
In enzymology, a pyrogallol 1,2-oxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1,2,3-trihydroxybenzene and O2, whereas its product is -5-oxohex-2-enedioate....

: chloridazon-catechol dioxygenase
Chloridazon-catechol dioxygenase
In enzymology, a chloridazon-catechol dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5-amino-4-chloro-2--3-pyridazinone and O2, whereas its product is 5-amino-4-chloro-2--3-pyridazinone.This enzyme belongs to the family of oxidoreductases,...

: hydroxyquinol 1,2-dioxygenase
Hydroxyquinol 1,2-dioxygenase
In enzymology, a hydroxyquinol 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are benzene-1,2,4-triol and O2, whereas its product is 3-hydroxy-cis,cis-muconate....

: 1-hydroxy-2-naphthoate 1,2-dioxygenase
1-hydroxy-2-naphthoate 1,2-dioxygenase
In enzymology, a 1-hydroxy-2-naphthoate 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1-hydroxy-2-naphthoate and O2, whereas its product is -4--2-oxobut-3-enoate....

: biphenyl-2,3-diol 1,2-dioxygenase
Biphenyl-2,3-diol 1,2-dioxygenase
In enzymology, a biphenyl-2,3-diol 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are biphenyl-2,3-diol and O2, whereas its two products are 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate and H2O....

: arachidonate 8-lipoxygenase
Arachidonate 8-lipoxygenase
In enzymology, an arachidonate 8-lipoxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are arachidonate and O2, whereas its product is --8-hydroperoxyicosa-5,9,11,14-tetraenoate....

: 2,4'-dihydroxyacetophenone dioxygenase
2,4'-dihydroxyacetophenone dioxygenase
In enzymology, a 2,4'-dihydroxyacetophenone dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2,4'-dihydroxyacetophenone and O2, whereas its two products are 4-hydroxybenzoate and formate....

: deleted: lignostilbene ab-dioxygenase: linoleate diol synthase
Linoleate diol synthase
In enzymology, a linoleate diol synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are linoleate and O2, whereas its product is --dihydroxyoctadeca-9,12-dienoate....

: linoleate 11-lipoxygenase
Linoleate 11-lipoxygenase
In enzymology, a linoleate 11-lipoxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are linoleate and O2, whereas its product is --11-hydroperoxyoctadeca-9,12-dienoate....

: 4-hydroxymandelate synthase
4-hydroxymandelate synthase
In enzymology, a 4-hydroxymandelate synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 4-hydroxyphenylpyruvate and O2, whereas its two products are 4-hydroxymandelate and CO2....

: 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
3-hydroxy-4-oxoquinoline 2,4-dioxygenase
In enzymology, a 3-hydroxy-4-oxoquinoline 2,4-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-hydroxy-1H-quinolin-4-one and O2, whereas its two products are N-formylanthranilate and CO....

: 3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase: chlorite O2-lyase
Chlorite O2-lyase
In enzymology, a chlorite O2-lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are chloride and O2, whereas its product is chlorite....

: acetylacetone-cleaving enzyme
Acetylacetone-cleaving enzyme
In enzymology, an acetylacetone-cleaving enzyme is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are pentane-2,4-dione and O2, whereas its two products are acetate and 2-oxopropanal....

: 9-cis-epoxycarotenoid dioxygenase: indoleamine 2,3-dioxygenase
Indoleamine 2,3-dioxygenase
Indoleamine-pyrrole 2,3-dioxygenase is an immunomodulatory enzyme produced by some alternatively activated macrophages and other immunoregulatory cells...

: Acireductone dioxygenase (Ni2+-requiring)
Acireductone dioxygenase (Ni2+-requiring)
In enzymology, an acireductone dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1,2-dihydroxy-5-pent-1-en-3-one and O2, whereas its 3 products are 3-propanoate, formate, and CO.This enzyme belongs to the family of oxidoreductases,...

: acireductone dioxygenase (Fe(2+)-requiring): sulfur oxygenase/reductase
Sulfur oxygenase/reductase
In enzymology, a sulfur oxygenase/reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are sulfur, H2O, and O2, whereas its 3 products are hydrogen sulfide, bisulfite, and H+....


EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)

: arginine 2-monooxygenase
Arginine 2-monooxygenase
In enzymology, an arginine 2-monooxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-arginine and O2, whereas its 3 products are 4-guanidinobutanamide, CO2, and H2O....

: lysine 2-monooxygenase
Lysine 2-monooxygenase
In enzymology, a lysine 2-monooxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-lysine and O2, whereas its 3 products are 5-aminopentanamide, CO2, and H2O....

: tryptophan 2-monooxygenase
Tryptophan 2-monooxygenase
In enzymology, a tryptophan 2-monooxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-tryptophan and O2, whereas its 3 products are acetamide, CO2, and H2O....

: lactate 2-monooxygenase
Lactate 2-monooxygenase
In enzymology, a lactate 2-monooxygenase is an enzyme that catalyzes the chemical reaction-lactate + O2 \rightleftharpoons acetate + CO2 + H2OThus, the two substrates of this enzyme are -lactate and O2, whereas its 3 products are acetate, CO2, and H2O....

: Renilla-luciferin 2-monooxygenase
Renilla-luciferin 2-monooxygenase
In enzymology, a Renilla-luciferin 2-monooxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are Renilla luciferin and O2, whereas its 3 products are oxidized Renilla luciferin, CO2, and hn....

: Cypridina-luciferin 2-monooxygenase
Cypridina-luciferin 2-monooxygenase
In enzymology, a Cypridina-luciferin 2-monooxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are Cypridina luciferin and O2, whereas its 3 products are oxidized Cypridina luciferin, CO2, and hn....

: Photinus-luciferin 4-monooxygenase (ATP-hydrolysing): Watasenia-luciferin 2-monooxygenase
Watasenia-luciferin 2-monooxygenase
In enzymology, a Watasenia-luciferin 2-monooxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are Watasenia luciferin and O2, whereas its 3 products are oxidized Watasenia luciferin, CO2, and hn....

: phenylalanine 2-monooxygenase
Phenylalanine 2-monooxygenase
In enzymology, a phenylalanine 2-monooxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-phenylalanine and O2, whereas its 3 products are 2-phenylacetamide, CO2, and H2O....

: covered by *EC 1.14.13.59: methylphenyltetrahydropyridine N-monooxygenase: apo-b-carotenoid-14',13'-dioxygenase: Oplophorus-luciferin 2-monooxygenase
Oplophorus-luciferin 2-monooxygenase
In enzymology, an Oplophorus-luciferin 2-monooxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are Oplophorus luciferin and O2, whereas its 3 products are oxidized Oplophorus luciferin, CO2, and hn....


EC 1.13.99 Miscellaneous

: inositol oxygenase
Inositol oxygenase
Inositol oxygenase is an iron-binding protein which functions in the kidney....

: now EC 1.14.12.10: tryptophan 2'-dioxygenase
Tryptophan 2'-dioxygenase
In enzymology, a tryptophan 2'-dioxygenase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-tryptophan and O2, whereas its 3 products are glycolaldehyde, CO2, and NH3....

: now EC 1.14.12.9: now EC 1.13.11.47

EC 1.14.1 With NADH or NADPH as one donor (deleted sub-subclass)

: now *EC 1.14.14.1: now *EC 1.14.13.9: deleted, covered by *EC 1.14.99.7, *EC 5.4.99.7: now *EC 1.14.99.2: now *EC 1.14.13.5: now *EC 1.14.15.4: now *EC 1.14.99.9: now *EC 1.14.99.10: deleted: now *EC 1.14.99.11: deleted

EC 1.14.2 With ascorbate as one donor (deleted sub-subclass)

: now EC 1.14.17.1: now EC 1.13.11.27

EC 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

: g-butyrobetaine dioxygenase: procollagen-proline dioxygenase
Procollagen-proline dioxygenase
In enzymology, a procollagen-proline dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are procollagen L-proline, 2-oxoglutarate, and O2, whereas its 3 products are procollagen trans-4-hydroxy-L-proline, succinate, and CO2.This enzyme belongs to the...

: pyrimidine-deoxynucleoside 2'-dioxygenase
Pyrimidine-deoxynucleoside 2'-dioxygenase
In enzymology, a pyrimidine-deoxynucleoside 2'-dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2'-deoxyuridine, 2-oxoglutarate, and O2, whereas its 3 products are uridine, succinate, and CO2....

: procollagen-lysine 5-dioxygenase: deleted, included in *EC 1.14.11.6: thymine dioxygenase
Thymine dioxygenase
In enzymology, a thymine dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are thymine, 2-oxoglutarate, and O2, whereas its 3 products are 5-hydroxymethyluracil, succinate, and CO2....

: procollagen-proline 3-dioxygenase
Procollagen-proline 3-dioxygenase
In enzymology, a procollagen-proline 3-dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are procollagen L-proline, 2-oxoglutarate, and O2, whereas its 3 products are procollagen trans-3-hydroxy-L-proline, succinate, and CO2.This enzyme belongs to the...

: trimethyllysine dioxygenase
Trimethyllysine dioxygenase
In enzymology, a trimethyllysine dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are N6,N6,N6-trimethyl-L-lysine, 2-oxoglutarate, and O2, whereas its 3 products are 3-hydroxy-N6,N6,N6-trimethyl-L-lysine, succinate, and CO2.This enzyme belongs to the...

: flavanone 3-dioxygenase
Flavanone 3-dioxygenase
In enzymology, a flavanone 3-dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are flavanone, 2-oxoglutarate, and O2, whereas its 3 products are dihydroflavonol, succinate, and CO2....

: pyrimidine-deoxynucleoside 1'-dioxygenase
Pyrimidine-deoxynucleoside 1'-dioxygenase
In enzymology, a pyrimidine-deoxynucleoside 1'-dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2'-deoxyuridine, 2-oxoglutarate, and O2, whereas its 4 products are uracil, 2-deoxyribonolactone, succinate, and CO2.This enzyme belongs to the family of...

: hyoscyamine (6S)-dioxygenase
Hyoscyamine (6S)-dioxygenase
In enzymology, a hyoscyamine -dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are L-hyoscyamine, 2-oxoglutarate, and O2, whereas its 3 products are -hydroxyhyoscyamine, succinate, and CO2....

: gibberellin-44 dioxygenase
Gibberellin-44 dioxygenase
In enzymology, a gibberellin-44 dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are gibberellin 44, 2-oxoglutarate, and O2, whereas its 3 products are gibberellin 19, succinate, and CO2....

: gibberellin 2b-dioxygenase: 6b-hydroxyhyoscyamine epoxidase: gibberellin 3b-dioxygenase: peptide-aspartate b-dioxygenase: taurine dioxygenase
Taurine dioxygenase
In enzymology, a taurine dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are taurine, 2-oxoglutarate, and O2, whereas its 4 products are sulfite, aminoacetaldehyde, succinate, and CO2....

: phytanoyl-CoA dioxygenase
Phytanoyl-CoA dioxygenase
In enzymology, a phytanoyl-CoA dioxygenase is an enzyme that catalyzes the chemical reactionThe three substrates of this enzyme are phytanoyl-CoA, 2-oxoglutarate, and O2, whereas its three products are 2-hydroxyphytanoyl-CoA, succinate, and CO2....

: leucocyanidin oxygenase
Leucocyanidin oxygenase
In enzymology, a leucocyanidin oxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are leucocyanidin, 2-oxoglutarate, and O2, whereas its 5 products are cis-dihydroquercetin, trans-dihydroquercetin, succinate, CO2, and H2O.This enzyme belongs to the family of...

: deacetoxyvindoline 4-hydroxylase
Deacetoxyvindoline 4-hydroxylase
In enzymology, a deacetoxyvindoline 4-hydroxylase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are deacetoxyvindoline, 2-oxoglutarate, and O2, whereas its 3 products are deacetylvindoline, succinate, and CO2....

: clavaminate synthase: flavone synthase
Flavone synthase
In enzymology, a flavone synthase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are flavanone, 2-oxoglutarate, and O2, whereas its 4 products are flavone, succinate, CO2, and H2O....

: flavonol synthase
Flavonol synthase
In enzymology, a flavonol synthase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are dihydroflavonol, 2-oxoglutarate, and O2, whereas its 4 products are flavonol, succinate, CO2, and H2O....

: 2'-deoxymugineic-acid 2'-dioxygenase
2'-deoxymugineic-acid 2'-dioxygenase
In enzymology, a 2'-deoxymugineic-acid 2'-dioxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2'-deoxymugineic acid, 2-oxoglutarate, and O2, whereas its 3 products are mugineic acid, succinate, and CO2....

: mugineic-acid 3-dioxygenase

EC 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor

: anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
Anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
In enzymology, an anthranilate 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are anthranilate, NADH, NADPH, H+, and O2, whereas its 5 products are catechol, CO2, NAD+, NADP+, and NH3.This enzyme belongs to the family of oxidoreductases,...

: now *EC 1.14.13.35: benzene 1,2-dioxygenase
Benzene 1,2-dioxygenase
In enzymology, a benzene 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are benzene, NADH, H+, and O2, whereas its two products are cis-cyclohexa-3,5-diene-1,2-diol and NAD+....

: 3-hydroxy-2-methylpyridinecarboxylate dioxygenase
3-hydroxy-2-methylpyridinecarboxylate dioxygenase
In enzymology, a 3-hydroxy-2-methylpyridinecarboxylate dioxygenase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are 3-hydroxy-2-methylpyridine-5-carboxylate, NADH, NADPH, H+, and O2, whereas its 3 products are 2-succinate, NAD+, and NADP+.This enzyme belongs to...

: 5-pyridoxate dioxygenase
5-pyridoxate dioxygenase
In enzymology, a 5-pyridoxate dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate, NADPH, H+, and O2, whereas its two products are 2--3-succinate and NADP+.This enzyme belongs to the family of...

: now *EC 1.14.13.66: phthalate 4,5-dioxygenase
Phthalate 4,5-dioxygenase
In enzymology, a phthalate 4,5-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are phthalate, NADH, H+, and O2, whereas its two products are cis-4,5-dihydroxycyclohexa-1,2-diene-1,2-dicarboxylate and NAD+....

: 4-sulfobenzoate 3,4-dioxygenase
4-sulfobenzoate 3,4-dioxygenase
In enzymology, a 4-sulfobenzoate 3,4-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 4-sulfobenzoate, NADH, H+, and O2, whereas its 3 products are 3,4-dihydroxybenzoate, sulfite, and NAD+....

: 4-chlorophenylacetate 3,4-dioxygenase
4-chlorophenylacetate 3,4-dioxygenase
In enzymology, a 4-chlorophenylacetate 3,4-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 4-chlorophenylacetate, NADH, H+, and O2, whereas its 3 products are 3,4-dihydroxyphenylacetate, chloride, and NAD+....

: benzoate 1,2-dioxygenase
Benzoate 1,2-dioxygenase
In enzymology, a benzoate 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are benzoate, NADH, H+, and O2, whereas its two products are 1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate and NAD+....

: toluene dioxygenase
Toluene dioxygenase
In enzymology, a toluene dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are toluene, NADH, H+, and O2, whereas its two products are -3-methylcyclohexa-3,5-diene-1,2-diol and NAD+....

: naphthalene 1,2-dioxygenase
Naphthalene 1,2-dioxygenase
In enzymology, a naphthalene 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are naphthalene, NADH, H+, and O2, whereas its two products are -1,2-dihydronaphthalene-1,2-diol and NAD+....

: 2-chlorobenzoate 1,2-dioxygenase
2-chlorobenzoate 1,2-dioxygenase
In enzymology, a 2-chlorobenzoate 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2-chlorobenzoate, NADH, H+, and O2, whereas its 4 products are catechol, chloride, NAD+, and CO2....

: 2-aminobenzenesulfonate 2,3-dioxygenase
2-aminobenzenesulfonate 2,3-dioxygenase
In enzymology, a 2-aminobenzenesulfonate 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2-aminobenzenesulfonate, NADH, H+, and O2, whereas its 3 products are 2,3-dihydroxybenzenesulfonate, NH3, and NAD+....

: terephthalate 1,2-dioxygenase
Terephthalate 1,2-dioxygenase
In enzymology, a terephthalate 1,2-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are terephthalate, NADH, H+, and O2, whereas its two products are -dihydroxycyclohexa-2,4-diene-1,4-dicarboxylate and NAD+....

: 2-hydroxyquinoline 5,6-dioxygenase
2-hydroxyquinoline 5,6-dioxygenase
In enzymology, a 2-hydroxyquinoline 5,6-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are quinolin-2-ol, NADH, H+, and O2, whereas its two products are 2,5,6-trihydroxy-5,6-dihydroquinoline and NAD+....

: nitric oxide dioxygenase
Nitric oxide dioxygenase
Nitric oxide dioxygenase is an enzyme that catalyzes the conversion of toxic nitric oxide to nitrate . The net reaction for the reaction catalyzed by nitric oxide dioxygenase is shown below:* 2NO + 2O2 + NADH → 2NO3- + NAD+ + H+...

: biphenyl 2,3-dioxygenase
Biphenyl 2,3-dioxygenase
In enzymology, a biphenyl 2,3-dioxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are biphenyl, NADH, H+, and O2, whereas its two products are -3-phenylcyclohexa-3,5-diene-1,2-diol and NAD+....

: 3-phenylpropionate dioxygenase

EC 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen

: salicylate 1-monooxygenase
Salicylate 1-monooxygenase
In enzymology, a salicylate 1-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are salicylate, NADH, H+, and O2, whereas its 4 products are catechol, NAD+, H2O, and CO2....

: 4-hydroxybenzoate 3-monooxygenase
4-hydroxybenzoate 3-monooxygenase
In enzymology, a 4-hydroxybenzoate 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 4-hydroxybenzoate, NADPH, H+, and O2, whereas its 3 products are protocatechuate, NADP+, and H2O....

: 4-hydroxyphenylacetate 3-monooxygenase
4-hydroxyphenylacetate 3-monooxygenase
In enzymology, a 4-hydroxyphenylacetate 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 4-hydroxyphenylacetate, NADH, H+, and O2, whereas its 3 products are 3,4-dihydroxyphenylacetate, NAD+, and H2O....

: melilotate 3-monooxygenase
Melilotate 3-monooxygenase
In enzymology, a melilotate 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 3-propanoate, NADH, H+, and O2, whereas its 3 products are 3-propanoate, NAD+, and H2O....

: imidazoleacetate 4-monooxygenase
Imidazoleacetate 4-monooxygenase
In enzymology, an imidazoleacetate 4-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 4-imidazoleacetate, NADH, H+, and O2, whereas its 3 products are 5-hydroxy-4-imidazoleacetate, NAD+, and H2O....

: orcinol 2-monooxygenase
Orcinol 2-monooxygenase
In enzymology, an orcinol 2-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are orcinol, NADH, H+, and O2, whereas its 3 products are 2,3,5-trihydroxytoluene, NAD+, and H2O....

: phenol 2-monooxygenase
Phenol 2-monooxygenase
In enzymology, a phenol 2-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are phenol, NADPH, H+, and O2, whereas its 3 products are catechol, NADP+, and H2O....

: dimethylaniline monooxygenase (N-oxide-forming): kynurenine 3-monooxygenase
Kynurenine 3-monooxygenase
In enzymology, a kynurenine 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are L-kynurenine, NADPH, H+, and O2, whereas its 3 products are 3-hydroxy-L-kynurenine, NADP+, and H2O....

: 2,6-dihydroxypyridine 3-monooxygenase
2,6-dihydroxypyridine 3-monooxygenase
In enzymology, a 2,6-dihydroxypyridine 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2,6-dihydroxypyridine, NADH, H+, and O2, whereas its 3 products are 2,3,6-trihydroxypyridine, NAD+, and H2O....

: trans-cinnamate 4-monooxygenase
Trans-cinnamate 4-monooxygenase
In enzymology, a trans-cinnamate 4-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are trans-cinnamate, NADPH, H+, and O2, whereas its 3 products are 4-hydroxycinnamate, NADP+, and H2O....

: benzoate 4-monooxygenase
Benzoate 4-monooxygenase
In enzymology, a benzoate 4-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are benzoate, NADPH, H+, and O2, whereas its 3 products are 4-hydroxybenzoate, NADP+, and H2O....

: calcidiol 1-monooxygenase: trans-cinnamate 2-monooxygenase
Trans-cinnamate 2-monooxygenase
In enzymology, a trans-cinnamate 2-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are trans-cinnamate, NADPH, H+, and O2, whereas its 3 products are 2-hydroxycinnamate, NADP+, and H2O....

: cholestanetriol 26-monooxygenase
Cholestanetriol 26-monooxygenase
In enzymology, a cholestanetriol 26-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 5beta-cholestane-3alpha,7alpha,12alpha-triol, NADPH, H+, and O2, whereas its 3 products are -5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol, NADP+, and H2O.This...

: cyclopentanone monooxygenase
Cyclopentanone monooxygenase
In enzymology, a cyclopentanone monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are cyclopentanone, NADPH, H+, and O2, whereas its 3 products are 5-valerolactone, NADP+, and H2O....

: cholesterol 7a-monooxygenase: 4-hydroxyphenylacetate 1-monooxygenase
4-hydroxyphenylacetate 1-monooxygenase
In enzymology, a 4-hydroxyphenylacetate 1-monooxygenase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are 4-hydroxyphenylacetate, NADH, NADPH, H+, and O2, whereas its 4 products are homogentisate, NAD+, NADP+, and H2O....

: taxifolin 8-monooxygenase
Taxifolin 8-monooxygenase
In enzymology, a taxifolin 8-monooxygenase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are taxifolin, NADH, NADPH, H+, and O2, whereas its 4 products are 2,3-dihydrogossypetin, NAD+, NADP+, and H2O....

: 2,4-dichlorophenol 6-monooxygenase
2,4-dichlorophenol 6-monooxygenase
In enzymology, a 2,4-dichlorophenol 6-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2,4-dichlorophenol, NADPH, H+, and O2, whereas its 3 products are 3,5-dichlorocatechol, NADP+, and H2O....

: flavonoid 3'-monooxygenase
Flavonoid 3'-monooxygenase
In enzymology, a flavonoid 3'-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are flavonoid, NADPH, H+, and O2, whereas its 3 products are 3'-hydroxyflavonoid, NADP+, and H2O....

: cyclohexanone monooxygenase: 3-hydroxybenzoate 4-monooxygenase
3-hydroxybenzoate 4-monooxygenase
In enzymology, a 3-hydroxybenzoate 4-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 3-hydroxybenzoate, NADPH, H+, and O2, whereas its 3 products are 3,4-dihydroxybenzoate, NADP+, and H2O....

: 3-hydroxybenzoate 6-monooxygenase
3-hydroxybenzoate 6-monooxygenase
In enzymology, a 3-hydroxybenzoate 6-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 3-hydroxybenzoate, NADH, H+, and O2, whereas its 3 products are 2,5-dihydroxybenzoate, NAD+, and H2O....

: methane monooxygenase
Methane monooxygenase
Methane monooxygenase, or MMO, is an enzyme capable of oxidizing the C-H bond in methane as well as other alkanes. Methane monooxygenase belongs to the class of oxidoreductase enzymes ....

: phosphatidylcholine 12-monooxygenase
Phosphatidylcholine 12-monooxygenase
In enzymology, a phosphatidylcholine 12-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine, NADH, H+, and O2, whereas its 3 products are 1-acyl-2-[-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine, NAD+, and...

: 4-aminobenzoate 1-monooxygenase
4-aminobenzoate 1-monooxygenase
In enzymology, a 4-aminobenzoate 1-monooxygenase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are 4-aminobenzoate, NADH, NADPH, H+, and O2, whereas its 5 products are 4-hydroxyaniline, NAD+, NADP+, H2O, and CO2....

: 3,9-dihydroxypterocarpan 6a-monooxygenase
3,9-dihydroxypterocarpan 6a-monooxygenase
In enzymology, a 3,9-dihydroxypterocarpan 6a-monooxygenase is an enzyme that catalyzes the chemical reaction-3,9-dihydroxypterocarpan + NADPH + H+ + O2 \rightleftharpoons -3,6a,9-trihydroxypterocarpan + NADP+ + H2O...

: 4-nitrophenol 2-monooxygenase
4-nitrophenol 2-monooxygenase
In enzymology, a 4-nitrophenol 2-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 4-nitrophenol, NADH, H+, and O2, whereas its 3 products are 4-nitrocatechol, NAD+, and H2O....

: leukotriene-B4 20-monooxygenase
Leukotriene-B4 20-monooxygenase
In enzymology, a leukotriene-B4 20-monooxygenase is an enzyme that catalyzes the chemical reaction--5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 \rightleftharpoons --5,12,20-trihydroxyicosa-6,8,10,14- tetraenoate + NADP+ + H2OThe 4 substrates of this enzyme are...

: 2-nitrophenol 2-monooxygenase
2-nitrophenol 2-monooxygenase
In enzymology, a 2-nitrophenol 2-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2-nitrophenol, NADPH, H+, and O2, whereas its 4 products are catechol, nitrite, NADP+, and H2O....

: albendazole monooxygenase
Albendazole monooxygenase
In enzymology, an albendazole monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are albendazole, NADPH, H+, and O2, whereas its 3 products are albendazole S-oxide, NADP+, and H2O....

: 4-hydroxybenzoate 3-monooxygenase (NAD(P)H)
4-hydroxybenzoate 3-monooxygenase (NAD(P)H)
In enzymology, a 4-hydroxybenzoate 3-monooxygenase [NADH] is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are 4-hydroxybenzoate, NADH, NADPH, H+, and O2, whereas its 4 products are 3,4-dihydroxybenzoate, NAD+, NADP+, and H2O.This enzyme belongs to the family of...

: leukotriene-E4 20-monooxygenase
Leukotriene-E4 20-monooxygenase
In enzymology, a leukotriene-E4 20-monooxygenase is an enzyme that catalyzes the chemical reaction--6--5-hydroxyicosa-7,9,11,14- tetraenoate + NADPH + H+ + O2 \rightleftharpoons 20-hydroxyleukotriene E4 + NADP+ + H2O...

: anthranilate 3-monooxygenase (deaminating)
Anthranilate 3-monooxygenase (deaminating)
In enzymology, an anthranilate 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are anthranilate, NADPH, H+, and O2, whereas its 3 products are 2,3-dihydroxybenzoate, NADP+, and NH3....

: 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
In enzymology, a 5-O--D-quinate 3'-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are trans-5-O--D-quinate, NADPH, H+, and O2, whereas its 3 products are trans-5-O-caffeoyl-D-quinate, NADP+, and H2O.This enzyme belongs to the family of...

: methyltetrahydroprotoberberine 14-monooxygenase
Methyltetrahydroprotoberberine 14-monooxygenase
In enzymology, a methyltetrahydroprotoberberine 14-monooxygenase is an enzyme that catalyzes the chemical reaction-N-methylcanadine + NADPH + H+ + O2 \rightleftharpoons allocryptopine + NADP+ + H2O...

: anhydrotetracycline monooxygenase
Anhydrotetracycline monooxygenase
In enzymology, an anhydrotetracycline monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are anhydrotetracycline, NADPH, H+, and O2, whereas its 3 products are 12-dehydrotetracycline, NADP+, and H2O....

: nitric-oxide synthase: anthraniloyl-CoA monooxygenase
Anthraniloyl-CoA monooxygenase
In enzymology, an anthraniloyl-CoA monooxygenase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are 2-aminobenzoyl-CoA, NADH, NADPH, H+, and O2, whereas its 4 products are 2-amino-5-oxocyclohex-1-enecarboxyl-CoA, H2O, NAD+, and NADP+.This enzyme belongs to the...

: tyrosine N-monooxygenase: hydroxyphenylacetonitrile 2-monooxygenase
Hydroxyphenylacetonitrile 2-monooxygenase
In enzymology, a hydroxyphenylacetonitrile 2-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 4-hydroxyphenylacetonitrile, NADPH, H+, and O2, whereas its 3 products are 4-hydroxymandelonitrile, NADP+, and H2O.This enzyme belongs to the family of...

: questin monooxygenase
Questin monooxygenase
In enzymology, a questin monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are questin, NADPH, H+, and O2, whereas its 3 products are demethylsulochrin, NADP+, and H2O....

: 2-hydroxybiphenyl 3-monooxygenase
2-hydroxybiphenyl 3-monooxygenase
In enzymology, a 2-hydroxybiphenyl 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2-hydroxybiphenyl, NADH, H+, and O2, whereas its 3 products are 2,3-dihydroxybiphenyl, NAD+, and H2O....

: now *EC 1.14.18.2: (-)-menthol monooxygenase
(-)-menthol monooxygenase
In enzymology, a -menthol monooxygenase is an enzyme that catalyzes the chemical reaction-menthol + NADPH + H+ + O2 \rightleftharpoons p-menthane-3,8-diol + NADP+ + H2O...

: (S)-limonene 3-monooxygenase
(S)-limonene 3-monooxygenase
In enzymology, a -limonene 3-monooxygenase is an enzyme that catalyzes the chemical reaction--limonene + NADPH + H+ + O2 \rightleftharpoons -trans-isopiperitenol + NADP+ + H2O...

: (S)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
In enzymology, a -limonene 6-monooxygenase is an enzyme that catalyzes the chemical reaction--limonene + NADPH + H+ + O2 \rightleftharpoons -trans-carveol + NADP+ + H2O...

: (S)-limonene 7-monooxygenase
(S)-limonene 7-monooxygenase
In enzymology, a -limonene 7-monooxygenase is an enzyme that catalyzes the chemical reaction--limonene + NADPH + H+ + O2 \rightleftharpoons -perillyl alcohol + NADP+ + H2O...

: pentachlorophenol monooxygenase: 6-oxocineole dehydrogenase
6-oxocineole dehydrogenase
In enzymology, a 6-oxocineole dehydrogenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 6-oxocineole, NADPH, H+, and O2, whereas its 3 products are 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one, NADP+, and H2O....

: isoflavone 3'-hydroxylase
Isoflavone 3'-hydroxylase
In enzymology, an isoflavone 3'-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are formononetin, NADPH, H+, and O2, whereas its 3 products are calycosin, NADP+, and H2O....

: 4'-methoxyisoflavone 2'-hydroxylase
4'-methoxyisoflavone 2'-hydroxylase
In enzymology, a 4'-methoxyisoflavone 2'-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are formononetin, NADPH, H+, and O2, whereas its 3 products are 2'-hydroxyformononetin, NADP+, and H2O....

: ketosteroid monooxygenase: protopine 6-monooxygenase
Protopine 6-monooxygenase
In enzymology, a protopine 6-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are protopine, NADPH, H+, and O2, whereas its 3 products are 6-hydroxyprotopine, NADP+, and H2O....

: dihydrosanguinarine 10-monooxygenase
Dihydrosanguinarine 10-monooxygenase
In enzymology, a dihydrosanguinarine 10-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are dihydrosanguinarine, NADPH, H+, and O2, whereas its 3 products are 10-hydroxydihydrosanguinarine, NADP+, and H2O....

: dihydrochelirubine 12-monooxygenase
Dihydrochelirubine 12-monooxygenase
In enzymology, a dihydrochelirubine 12-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are dihydrochelirubine, NADPH, H+, and O2, whereas its 3 products are 12-hydroxydihydrochelirubine, NADP+, and H2O....

: benzoyl-CoA 3-monooxygenase
Benzoyl-CoA 3-monooxygenase
In enzymology, a benzoyl-CoA 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are benzoyl-CoA, NADPH, H+, and O2, whereas its 3 products are 3-hydroxybenzoyl-CoA, NADP+, and H2O....

: L-lysine 6-monooxygenase (NADPH)
L-lysine 6-monooxygenase (NADPH)
In enzymology, a L-lysine 6-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are L-lysine, NADPH, H+, and O2, whereas its 3 products are N6-hydroxy-L-lysine, NADP+, and H2O....

: 27-hydroxycholesterol 7a-monooxygenase: 2-hydroxyquinoline 8-monooxygenase
2-hydroxyquinoline 8-monooxygenase
In enzymology, a 2-hydroxyquinoline 8-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are quinolin-2-ol, NADH, H+, and O2, whereas its 3 products are quinolin-2,8-diol, NAD+, and H2O....

: 4-hydroxyquinoline 3-monooxygenase
4-hydroxyquinoline 3-monooxygenase
In enzymology, a 4-hydroxyquinoline 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are quinolin-4-ol, NADH, H+, and O2, whereas its 3 products are quinolin-3,4-diol, NAD+, and H2O....

: 3-hydroxyphenylacetate 6-hydroxylase
3-hydroxyphenylacetate 6-hydroxylase
In enzymology, a 3-hydroxyphenylacetate 6-hydroxylase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are 3-hydroxyphenylacetate, NADH, NADPH, H+, and O2, whereas its 4 products are 2,5-dihydroxyphenylacetate, NAD+, NADP+, and H2O.This enzyme belongs to the family...

: 4-hydroxybenzoate 1-hydroxylase
4-hydroxybenzoate 1-hydroxylase
In enzymology, a 4-hydroxybenzoate 1-hydroxylase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are 4-hydroxybenzoate, NADH, NADPH, H+, and O2, whereas its 5 products are hydroquinone, NAD+, NADP+, H2O, and CO2....

: 2-hydroxyquinoline 8-monooxygenase
2-hydroxyquinoline 8-monooxygenase
In enzymology, a 2-hydroxyquinoline 8-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are quinolin-2-ol, NADH, H+, and O2, whereas its 3 products are quinolin-2,8-diol, NAD+, and H2O....

: 2-hydroxycyclohexanone 2-monooxygenase
2-hydroxycyclohexanone 2-monooxygenase
In enzymology, a 2-hydroxycyclohexanone 2-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 2-hydroxycyclohexan-1-one, NADPH, H+, and O2, whereas its 3 products are 6-hydroxyhexan-6-olide, NADP+, and H2O....

: quinine 3-monooxygenase
Quinine 3-monooxygenase
In enzymology, a quinine 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are quinine, NADPH, H+, and O2, whereas its 3 products are 3-hydroxyquinine, NADP+, and H2O....

: 4-hydroxyphenylacetaldehyde oxime monooxygenase
4-hydroxyphenylacetaldehyde oxime monooxygenase
In enzymology, a 4-hydroxyphenylacetaldehyde oxime monooxygenase is an enzyme that catalyzes the chemical reaction-4-hydroxyphenylacetaldehyde oxime + NADPH + H+ + O2 \rightleftharpoons -4-hydroxymandelonitrile + NADP+ + 2 H2O...

: alkene monooxygenase
Alkene monooxygenase
In enzymology, an alkene monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are propene, NADH, H+, and O2, whereas its 3 products are 1,2-epoxypropane, NAD+, and H2O....

: sterol 14-demethylase
Sterol 14-demethylase
In enzymology, a sterol 14-demethylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are obtusifoliol, O2, NADPH, and H+, whereas its 4 products are 4alpha-methyl-5alpha-ergosta-8,14,24-trien-3beta-ol, formate, NADP+, and H2O.This enzyme belongs to the family of...

: N-methylcoclaurine 3'-monooxygenase
N-methylcoclaurine 3'-monooxygenase
In enzymology, a N-methylcoclaurine 3'-monooxygenase is an enzyme that catalyzes the chemical reaction-N-methylcoclaurine + NADPH + H+ + O2 \rightleftharpoons -3'-hydroxy-N-methylcoclaurine + NADP+ + H2O...

: methylsterol monooxygenase: tabersonine 16-hydroxylase
Tabersonine 16-hydroxylase
In enzymology, a tabersonine 16-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are tabersonine, NADPH, H+, and O2, whereas its 3 products are 16-hydroxytabersonine, NADP+, and H2O....

: 7-deoxyloganin 7-hydroxylase
7-deoxyloganin 7-hydroxylase
In enzymology, a 7-deoxyloganin 7-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 7-deoxyloganin, NADPH, H+, and O2, whereas its 3 products are loganin, NADP+, and H2O....

: vinorine hydroxylase
Vinorine hydroxylase
In enzymology, a vinorine hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are vinorine, NADPH, H+, and O2, whereas its 3 products are vomilenine, NADP+, and H2O....

: taxane 10b-hydroxylase: taxane 13a-hydroxylase: ent-kaurene oxidase: ent-kaurenoic acid oxidase: (R)-limonene 6-monooxygenase
(R)-limonene 6-monooxygenase
In enzymology, a -limonene 6-monooxygenase is an enzyme that catalyzes the chemical reaction--limonene + NADPH + H+ + O2 \rightleftharpoons -trans-carveol + NADP+ + H2O...

: magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase: vanillate monooxygenase
Vanillate monooxygenase
In enzymology, a vanillate monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are vanillate, O2, NADH, and H+, whereas its 4 products are 3,4-dihydroxybenzoate, NAD+, H2O, and formaldehyde....

: precorrin-3B synthase
Precorrin-3B synthase
In enzymology, a precorrin-3B synthase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are precorrin 3A, NADH, H+, and O2, whereas its 3 products are precorrin 3B, NAD+, and H2O....

: 4-hydroxyacetophenone monooxygenase
4-hydroxyacetophenone monooxygenase
In enzymology, a 4-hydroxyacetophenone monooxygenase is an enzyme that catalyzes the chemical reactionethan-1-one + NADPH + H+ + O2 \rightleftharpoons 4-hydroxyphenyl acetate + NADP+ + H2O...

: glyceollin synthase
Glyceollin synthase
In enzymology, a glyceollin synthase is an enzyme that catalyzes the last committed step in glyceollin biosynthesis. This enzyme has been classified as a cytochrome dependent monooxygenase...

: 2-hydroxyisoflavanone synthase
2-hydroxyisoflavanone synthase
In enzymology, a 2-hydroxyisoflavanone synthase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are apigenin, NADPH, H+, and O2, whereas its 3 products are 2-hydroxy-2,3-dihydrogenistein, NADP+, and H2O....

: licodione synthase
Licodione synthase
In enzymology, a licodione synthase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are liquiritigenin, NADPH, H+, and O2, whereas its 3 products are licodione, NADP+, and H2O....

: flavonoid 3',5'-hydroxylase: isoflavone 2'-hydroxylase
Isoflavone 2'-hydroxylase
In enzymology, an isoflavone 2'-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are isoflavone, NADPH, H+, and O2, whereas its 3 products are 2'-hydroxyisoflavone, NADP+, and H2O....

: zeaxanthin epoxidase: deoxysarpagine hydroxylase
Deoxysarpagine hydroxylase
In enzymology, a deoxysarpagine hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 10-deoxysarpagine, NADPH, H+, and O2, whereas its 3 products are sarpagine, NADP+, and H2O....

: phenylacetone monooxygenase
Phenylacetone monooxygenase
In enzymology, a phenylacetone monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are phenylacetone, NADPH, H+, and O2, whereas its 3 products are benzyl acetate, NADP+, and H2O....

: (+)-abscisic acid 8'-hydroxylase
(+)-abscisic acid 8'-hydroxylase
In enzymology, a -abscisic acid 8'-hydroxylase is an enzyme that catalyzes the chemical reaction-abscisate + NADPH + H+ + O2 \rightleftharpoons 8'-hydroxyabscisate + NADP+ + H2O...

: Lithocholate 6beta-hydroxylase
Lithocholate 6beta-hydroxylase
In enzymology, a lithocholate 6beta-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are lithocholate, NADPH, H+, and O2, whereas its 3 products are 6beta-hydroxylithocholate, NADP+, and H2O....

: 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
In enzymology, a 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 7alpha-hydroxycholest-4-en-3-one In enzymology, a 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase is an enzyme that catalyzes the...

: 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
In enzymology, a 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 5beta-cholestane-3alpha,7alpha-diol, NADPH, H+, and O2, whereas its 3 products are 5beta-cholestane-3alpha,7alpha,12alpha-triol, NADP+, and...

: taurochenodeoxycholate 6α-hydroxylase: cholesterol 24-hydroxylase
Cholesterol 24-hydroxylase
In enzymology, a cholesterol 24-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are cholesterol, NADPH, H+, and O2, whereas its 3 products are -24-hydroxycholesterol, NADP+, and H2O....

: 24-hydroxycholesterol 7α-hydroxylase: 25-hydroxycholesterol 7α-hydroxylase: senecionine N-oxygenase
Senecionine N-oxygenase
In enzymology, a senecionine N-oxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are senecionine, NADPH, H+, and O2, whereas its 3 products are senecionine N-oxide, NADP+, and H2O....

: psoralen synthase
Psoralen synthase
In enzymology, a psoralen synthase is an enzyme that catalyzes the chemical reaction-marmesin + NADPH + H+ + O2 \rightleftharpoons psoralen + NADP+ + acetone + 2 H2O...

: 8-dimethylallylnaringenin 2'-hydroxylase
8-dimethylallylnaringenin 2'-hydroxylase
In enzymology, a 8-dimethylallylnaringenin 2'-hydroxylase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are sophoraflavanone B, NADPH, H+, and O2, whereas its 3 products are leachianone G, NADP+, and H2O....

: (+)-menthofuran synthase: monocyclic monoterpene ketone monooxygenase: epi-isozizaene 5-monooxygenase: limonene 1,2-monooxygenase: abietadiene hydroxylase : abietadienol hydroxylase : geranylgeraniol 18-hydroxylase : methanesulfonate monooxygenase: 3-epi-6-deoxocathasterone 23-monooxygenase: FAD-dependent urate hydroxylase: 6-hydroxynicotinate 3-monooxygenase: angelicin synthase

EC 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

: unspecific monooxygenase
Unspecific monooxygenase
In enzymology, an unspecific monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are RH, reduced flavoprotein, and O2, whereas its 3 products are ROH, oxidized flavoprotein, and H2O....

: deleted, included in EC 1.14.14.1: alkanal monooxygenase (FMN-linked)
Alkanal monooxygenase (FMN-linked)
In enzymology, an alkanal monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are RCHO, reduced FMN, and O2, whereas its 4 products are RCOOH, FMN, H2O, and hn....

: deleted, identical to EC 1.14.15.7: alkanesulfonate monooxygenase
Alkanesulfonate monooxygenase
In enzymology, an alkanesulfonate monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are alkanesulfonate , FMNH2, and O2, whereas its 4 products are aldehyde, FMN, sulfite, and H2O....


EC 1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

: camphor 5-monooxygenase
Camphor 5-monooxygenase
In enzymology, a camphor 5-monooxygenase is an enzyme that catalyzes the chemical reaction-camphor + putidaredoxin + O2 \rightleftharpoons -exo-5-hydroxycamphor + oxidized putidaredoxin + H2O...

: camphor 1,2-monooxygenase
Camphor 1,2-monooxygenase
In enzymology, a camphor 1,2-monooxygenase is an enzyme that catalyzes the chemical reaction-bornane-2,5-dione + reduced rubredoxin + O2 \rightleftharpoons 5-oxo-1,2-campholide + oxidized rubredoxin + H2O...

: alkane 1-monooxygenase
Alkane 1-monooxygenase
In enzymology, an alkane 1-monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are octane, reduced rubredoxin, and O2, whereas its 3 products are 1-octanol, oxidized rubredoxin, and H2O....

: steroid 11b-monooxygenase: corticosterone 18-monooxygenase
Corticosterone 18-monooxygenase
In enzymology, a corticosterone 18-monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are corticosterone, reduced adrenal ferredoxin, and O2, whereas its 3 products are 18-hydroxycorticosterone, oxidized adrenal ferredoxin, and H2O.This enzyme belongs to...

: cholesterol monooxygenase (side-chain-cleaving): choline monooxygenase
Choline monooxygenase
In enzymology, a choline monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are choline, O2, reduced ferredoxin, and H+, whereas its 3 products are betaine aldehyde hydrate, H2O, and oxidized ferredoxin....


EC 1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen

: phenylalanine 4-monooxygenase: tyrosine 3-monooxygenase: anthranilate 3-monooxygenase
Anthranilate 3-monooxygenase
In enzymology, an anthranilate 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are anthranilate, tetrahydrobiopterin, and O2, whereas its 3 products are 3-hydroxyanthranilate, dihydrobiopterin, and H2O....

: tryptophan 5-monooxygenase: glyceryl-ether monooxygenase
Glyceryl-ether monooxygenase
Alkylglycerol monooxygenase is an enzyme that catalyzes the hydroxylation of alkylglycerols, a specific subclass of ether lipids. This enzyme was first described in 1964 as a pteridine-dependent etherlipid cleaving enzyme...

: mandelate 4-monooxygenase
Mandelate 4-monooxygenase
In enzymology, a mandelate 4-monooxygenase is an enzyme that catalyzes the chemical reaction-2-hydroxy-2-phenylacetate + tetrahydrobiopterin + O2 \rightleftharpoons -4-hydroxymandelate + dihydrobiopterin + H2O...


EC 1.14.17 With reduced ascorbate as one donor, and incorporation of one atom of oxygen

: dopamine b-monooxygenase: deleted, included in EC 1.14.18.1: peptidylglycine monooxygenase
Peptidylglycine monooxygenase
In enzymology, a peptidylglycine monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are peptidylglycine, ascorbate, and O2, whereas its 3 products are peptidyl, dehydroascorbate, and H2O....

: aminocyclopropanecarboxylate oxidase
Aminocyclopropanecarboxylate oxidase
In enzymology, an aminocyclopropanecarboxylate oxidase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 1-aminocyclopropane-1-carboxylate, ascorbate, and O2, whereas its 5 products are ethylene, cyanide, dehydroascorbate, CO2, and H2O.This enzyme belongs to the...


EC 1.14.18 With another compound as one donor, and incorporation of one atom of oxygen

: monophenol monooxygenase: CMP-N-acetylneuraminate monooxygenase
CMP-N-acetylneuraminate monooxygenase
In enzymology, a CMP-N-acetylneuraminate monooxygenase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are CMP-N-acetylneuraminate, ferrocytochrome b5, O2, and H+, whereas its 3 products are CMP-N-glycoloylneuraminate, ferricytochrome b5, and H2O.This enzyme...


EC 1.14.19 With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

: stearoyl-CoA 9-desaturase
Stearoyl-CoA 9-desaturase
In enzymology, a stearoyl-CoA 9-desaturase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are stearoyl-CoA, ferrocytochrome b5, O2, and H+, whereas its 3 products are oleoyl-CoA, ferricytochrome b5, and H2O....

: acyl-(acyl-carrier-protein) desaturase
Acyl-(acyl-carrier-protein) desaturase
In enzymology, an acyl-[acyl-carrier-protein] desaturase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are stearoyl-[acyl-carrier-protein], reduced acceptor, and O2, whereas its 3 products are oleoyl-[acyl-carrier-protein], acceptor, and H2O.This enzyme belongs...

: linoleoyl-CoA desaturase
Linoleoyl-CoA desaturase
In enzymology, a linoleoyl-CoA desaturase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are linoleoyl-CoA, an electron acceptor AH2, and O2, whereas its 3 products are gamma-linolenoyl-CoA, the reduction product A, and H2O....


EC 1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated

: deacetoxycephalosporin-C synthase
Deacetoxycephalosporin-C synthase
In enzymology, a deacetoxycephalosporin-C synthase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are penicillin N, 2-oxoglutarate, and O2, whereas its 4 products are deacetoxycephalosporin C, succinate, CO2, and H2O....


EC 1.14.21 With NADH or NADPH as one donor, and the other dehydrogenated

: (S)-stylopine synthase
(S)-stylopine synthase
In enzymology, a -stylopine synthase is an enzyme that catalyzes the chemical reaction-cheilanthifoline + NADPH + H+ + O2 \rightleftharpoons -stylopine + NADP+ + 2 H2O...

: (S)-cheilanthifoline synthase
(S)-cheilanthifoline synthase
In enzymology, a -cheilanthifoline synthase is an enzyme that catalyzes the chemical reaction-scoulerine + NADPH + H+ + O2 \rightleftharpoons -cheilanthifoline + NADP+ + 2 H2O...

: berbamunine synthase
Berbamunine synthase
In enzymology, a berbamunine synthase is an enzyme that catalyzes the chemical reaction-N-methylcoclaurine + -N-methylcoclaurine + NADPH + H+ + O2 \rightleftharpoons berbamunine + NADP+ + 2 H2O...

: salutaridine synthase
Salutaridine synthase
In enzymology, a salutaridine synthase is an enzyme that catalyzes the chemical reaction-reticuline + NADPH + H+ + O2 \rightleftharpoons salutaridine + NADP+ + 2 H2O...

: (S)-canadine synthase
(S)-canadine synthase
In enzymology, a -canadine synthase is an enzyme that catalyzes the chemical reaction-tetrahydrocolumbamine + NADPH + H+ + O2 \rightleftharpoons -canadine + NADP+ + 2 H2O...


EC 1.14.99 Miscellaneous

: prostaglandin-endoperoxide synthase: kynurenine 7,8-hydroxylase
Kynurenine 7,8-hydroxylase
In enzymology, a kynurenine 7,8-hydroxylase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are kynurenate, an electron acceptor AH2, and O2, whereas its two products are 7,8-dihydro-7,8-dihydroxykynurenate and the reduction product A.This enzyme belongs to the...

: heme oxygenase (decyclizing): progesterone monooxygenase
Progesterone monooxygenase
In enzymology, a progesterone monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are progesterone, AH2, and O2, whereas its 3 products are testosterone acetate, A, and H2O....

: now *EC 1.14.19.1: now *EC 1.14.19.2: squalene monooxygenase
Squalene monooxygenase
Squalene monooxygenase is an enzyme that uses NADPH and molecular oxygen to oxidize squalene to 2,3-oxidosqualene . Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway...

: deleted, included in *EC 1.14.14.1: steroid 17a-monooxygenase: steroid 21-monooxygenase: estradiol 6b-monooxygenase: 4-androstene-3,17-dione monooxygenase: now *EC 1.14.13.23: progesterone 11a-monooxygenase: 4-methoxybenzoate monooxygenase (O-demethylating)
4-methoxybenzoate monooxygenase (O-demethylating)
In enzymology, a 4-methoxybenzoate monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-methoxybenzoate, an electron acceptor AH2, and O2, whereas its 4 products are 4-hydroxybenzoate, formaldehyde, the reduction product A, and H2O.This enzyme...

: now *EC 1.14.13.72: now *EC 1.14.16.5: deleted: plasmanylethanolamine desaturase
Plasmanylethanolamine desaturase
In enzymology, a plasmanylethanolamine desaturase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine, an electron acceptor AH2, and O2, whereas its 3 products are...

: phylloquinone monooxygenase (2,3-epoxidizing)
Phylloquinone monooxygenase (2,3-epoxidizing)
In enzymology, a phylloquinone monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are phylloquinone, an electron acceptor AH2, and O2, whereas its 3 products are 2,3-epoxyphylloquinone, the reduction product A, and H2O.This enzyme belongs to the family...

: Latia-luciferin monooxygenase (demethylating)
Latia-luciferin monooxygenase (demethylating)
In enzymology, a Latia-luciferin monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are Latia luciferin, an electron acceptor AH2, and O2, whereas its 6 products are oxidized Latia luciferin, CO2, formate, the reduction product A, H2O, and hn.This...

: ecdysone 20-monooxygenase
Ecdysone 20-monooxygenase
In enzymology, an ecdysone 20-monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are ecdysone, an electron acceptor AH2, and O2, whereas its 3 products are 20-hydroxyecdysone, the reduction product A, and H2O....

: 3-hydroxybenzoate 2-monooxygenase
3-hydroxybenzoate 2-monooxygenase
In enzymology, a 3-hydroxybenzoate 2-monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 3-hydroxybenzoate, an electron acceptor AH2, and O2, whereas its 3 products are 2,3-dihydroxybenzoate, the reduction product A, and H2O.This enzyme belongs to the...

: steroid 9a-monooxygenase: now *EC 1.14.19.3: 2-hydroxypyridine 5-monooxygenase
2-hydroxypyridine 5-monooxygenase
In enzymology, a 2-hydroxypyridine 5-monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 2-hydroxypyridine, an electron acceptor AH2, and O2, whereas its 3 products are 2,5-dihydroxypyridine, the reduction product A, and H2O.This enzyme belongs to the...

: juglone 3-monooxygenase
Juglone 3-monooxygenase
In enzymology, juglone 3-monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 5-hydroxy-1,4-naphthoquinone, AH2, and O2, whereas its 3 products are 3,5-dihydroxy-1,4-naphthoquinone, A, and H2O....

: linalool 8-monooxygenase
Linalool 8-monooxygenase
In enzymology, a linalool 8-monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 3,7-dimethylocta-1,6-dien-3-ol, an electron acceptor AH2, and O2, whereas its 3 products are -3,7-dimethylocta-1,6-diene-3,8-diol, the reduction product A, and H2O.This...

: deoxyhypusine monooxygenase
Deoxyhypusine monooxygenase
In enzymology, a deoxyhypusine monooxygenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are a protein-bound N6--L-lysine, an electron acceptor AH2, and O2, and its 3 products are protein-bound N6-[-4-amino-2-hydroxybutyl]-L-lysine, the reduction product A, and...

: carotene 7,8-desaturase
Carotene 7,8-desaturase
In enzymology, a carotene 7,8-desaturase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are neurosporene, an electron acceptor AH2, and O2, whereas its 3 products are lycopene, the reduction product A, and H2O....

: myristoyl-CoA 11-(E) desaturase
Myristoyl-CoA 11-(E) desaturase
In enzymology, a myristoyl-CoA 11- desaturase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are myristoyl-CoA, NADH, NADPH, H+, and O2, whereas its 4 products are -11-tetradecenoyl-CoA, NAD+, NADP+, and H2O....

: myristoyl-CoA 11-(Z) desaturase
Myristoyl-CoA 11-(Z) desaturase
In enzymology, a myristoyl-CoA 11- desaturase is an enzyme that catalyzes the chemical reactionThe 5 substrates of this enzyme are myristoyl-CoA, NADH, NADPH, H+, and O2, whereas its 4 products are -11-tetradecenoyl-CoA, NAD+, NADP+, and H2O....

: D12-fatty acid dehydrogenase: monoprenyl isoflavone epoxidase
Monoprenyl isoflavone epoxidase
In enzymology, a monoprenyl isoflavone epoxidase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are 7-O-methylluteone, NADPH, H+, and O2, whereas its 3 products are dihydrofurano derivative, NADP+, and H2O....

: thiophene-2-carbonyl-CoA monooxygenase
Thiophene-2-carbonyl-CoA monooxygenase
In enzymology, a thiophene-2-carbonyl-CoA monooxygenase is an enzyme that catalyzes the chemical reactionThe three substrates of this enzyme are thiophene-2-carbonyl-CoA, an electron acceptor AH2, and O2, whereas its 3 products are 5-hydroxythiophene-2-carbonyl-CoA, the reduction product A, and...

: b-carotene 15,15'-monooxygenase: taxadiene 5a-hydroxylase

EC 1.16.1 With NAD or NADP as acceptor

: mercury(II) reductase
Mercury(II) reductase
In enzymology, a mercury reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are Hg, NADP+, and H+, whereas its two products are Hg2+ and NADPH....

: diferric-transferrin reductase
Diferric-transferrin reductase
In enzymology, a diferric-transferrin reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are transferrin[Fe]2, NAD+, and H+, whereas its two products are transferrin[Fe]2 and NADH....

: aquacobalamin reductase
Aquacobalamin reductase
In enzymology, an aquacobalamin reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cobalamin and NAD+, whereas its 3 products are aquacobalamin, NADH, and H+....

: cob(II)alamin reductase
Cob(II)alamin reductase
In enzymology, a cobalamin reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cobalamin and NAD+, whereas its 3 products are cobalamin, NADH, and H+....

: aquacobalamin reductase (NADPH)
Aquacobalamin reductase (NADPH)
In enzymology, an aquacobalamin reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cobalamin and NADP+, whereas its 3 products are aquacobalamin, NADPH, and H+....

: cyanocobalamin reductase (cyanide-eliminating)
Cyanocobalamin reductase (cyanide-eliminating)
In enzymology, a cyanocobalamin reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are cobalamin, cyanide, and NADP+, whereas its 3 products are cyanocobalamin, NADPH, and H+....

: ferric-chelate reductase
Ferric-chelate reductase
In enzymology, a ferric-chelate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are Fe and NAD+, whereas its 3 products are Fe, NADH, and H+....

: (methionine synthase) reductase
(methionine synthase) reductase
In enzymology, a [methionine synthase] reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are methionine synthase-methylcobalamin, S-adenosylhomocysteine, and NADP+, whereas its 4 products are methionine synthase-cobalamin, NADPH, H+, and...


EC 1.17.1 With NAD or NADP as acceptor

: CDP-4-dehydro-6-deoxyglucose reductase
CDP-4-dehydro-6-deoxyglucose reductase
In enzymology, a CDP-4-dehydro-6-deoxyglucose reductase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are CDP-4-dehydro-3,6-dideoxy-D-glucose, NAD+, NADP+, and H2O, whereas its 4 products are CDP-4-dehydro-6-deoxy-D-glucose, NADH, NADPH, and H+.This enzyme...

: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
4-hydroxy-3-methylbut-2-enyl diphosphate reductase is an enzyme in the non-mevalonate pathway.It acts upon -4-Hydroxy-3-methyl-but-2-enyl pyrophosphate .It is classified under ....

: leucoanthocyanidin reductase
Leucoanthocyanidin reductase
In enzymology, a leucoanthocyanidin reductase is an enzyme that catalyzes the chemical reaction-catechin + NADP+ + H2O \rightleftharpoons 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+...

: xanthine dehydrogenase
Xanthine dehydrogenase
Xanthine dehydrogenase, also known as XDH, is a protein that, in humans, is encoded by the XDH gene.-Function:Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer...

: nicotinate dehydrogenase
Nicotinate dehydrogenase
In enzymology, a nicotinate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are nicotinate, H2O, and NADP+, whereas its 3 products are 6-hydroxynicotinate, NADPH, and H+....


EC 1.17.3 With oxygen as acceptor

: pteridine oxidase
Pteridine oxidase
In enzymology, a pteridine oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2-amino-4-hydroxypteridine and O2, whereas its product is 2-amino-4,7-dihydroxypteridine....

: xanthine oxidase
Xanthine oxidase
Xanthine oxidase Xanthine oxidase Xanthine oxidase (XO (sometimes 'XAO'), a form of xanthine oxidoreductase that generates reactive oxygen species. Is an enzyme that catalyzes the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid...

: 6-hydroxynicotinate dehydrogenase
6-hydroxynicotinate dehydrogenase
In enzymology, a 6-hydroxynicotinate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 6-hydroxynicotinate, H2O, and O2, whereas its two products are 2,6-dihydroxynicotinate and H2O2....


EC 1.17.4 With a disulfide as acceptor

: ribonucleoside-diphosphate reductase: ribonucleoside-triphosphate reductase

EC 1.17.7 With an iron-sulfur protein as acceptor

: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
In enzymology, a 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase is an enzyme that catalyzes the chemical reaction-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + protein-disulfide \rightleftharpoons 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + protein-dithiolThe 3 substrates of this...


EC 1.17.99 With other acceptors

: 4-cresol dehydrogenase (hydroxylating)
4-cresol dehydrogenase (hydroxylating)
In enzymology, a 4-cresol dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are 4-cresol, acceptor, and H2O, whereas its two products are 4-hydroxybenzaldehyde and reduced acceptor....

: ethylbenzene hydroxylase
Ethylbenzene hydroxylase
In enzymology, an ethylbenzene hydroxylase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are ethylbenzene, H2O, and acceptor, whereas its two products are -1-phenylethanol and reduced acceptor....

: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase
In enzymology, a 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase is an enzyme that catalyzes the chemical reaction-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor \rightleftharpoons -3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-...


EC 1.18.1 With NAD+ or NADP+ as acceptor

: rubredoxin—NAD+ reductase: ferredoxin—NADP+ reductase: ferredoxin—NAD+ reductase: rubredoxin—NAD(P)+ reductase

EC 1.20.1 Acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor

: phosphonate dehydrogenase
Phosphonate dehydrogenase
In enzymology, a phosphonate dehydrogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are phosphonate, NAD+, and H2O, whereas its 3 products are phosphate, NADH, and H+....


EC 1.20.4 Acting on phosphorus or arsenic in donors, with disulfide as acceptor

: arsenate reductase (glutaredoxin)
Arsenate reductase (glutaredoxin)
In enzymology, an arsenate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are arsenate and glutaredoxin, whereas its 3 products are arsenite, glutaredoxin disulfide, and H2O....

: methylarsonate reductase
Methylarsonate reductase
In enzymology, a methylarsonate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are methylarsonate and glutathione, whereas its 3 products are methylarsonite, glutathione disulfide, and H2O....


EC 1.20.98 Acting on phosphorus or arsenic in donors, with other, known acceptors

: arsenate reductase (azurin)
Arsenate reductase (azurin)
In enzymology, an arsenate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are arsenite, H2O, and azurinox, whereas its 3 products are arsenate, azurinred, and H+....


EC 1.20.99 Acting on phosphorus or arsenic in donors, with other acceptors

: arsenate reductase (donor)
Arsenate reductase (donor)
In enzymology, an arsenate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are arsenite and acceptor, whereas its two products are arsenate and reduced acceptor....


EC 1.21.3 With oxygen as acceptor

: isopenicillin-N synthase
Isopenicillin-N synthase
Isopenicillin-N synthase is a non-heme iron-dependent enzyme belonging to the oxidoreductase family. This enzyme catalyzes the formation of isopenicillin-N from δ--L-cysteinyl-D-valine ....

: columbamine oxidase
Columbamine oxidase
In enzymology, a columbamine oxidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are columbamine and O2, whereas its two products are berberine and H2O....

: reticuline oxidase
Reticuline oxidase
In enzymology, a reticuline oxidase is an enzyme that catalyzes the chemical reaction-reticuline + O2 \rightleftharpoons -scoulerine + H2O2...

: sulochrin oxidase ((+)-bisdechlorogeodin-forming)
Sulochrin oxidase ((+)-bisdechlorogeodin-forming)
In enzymology, a sulochrin oxidase [-bisdechlorogeodin-forming] is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are sulochrin and O2, whereas its two products are -bisdechlorogeodin and H2O....

: sulochrin oxidase ((-)-bisdechlorogeodin-forming)
Sulochrin oxidase ((-)-bisdechlorogeodin-forming)
In enzymology, a sulochrin oxidase [-bisdechlorogeodin-forming] is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are sulochrin and O2, whereas its two products are -bisdechlorogeodin and H2O....

: aureusidin synthase

EC 1.21.4 With a disulfide as acceptor

: D-proline reductase (dithiol)
D-proline reductase (dithiol)
In enzymology, a D-proline reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 5-aminopentanoate and lipoate, whereas its two products are D-proline and dihydrolipoate....

: glycine reductase
Glycine reductase
In enzymology, a glycine reductase is an enzyme that catalyzes the chemical reactionThe 4 substrates of this enzyme are acetyl phosphate, NH3, thioredoxin disulfide, and H2O, whereas its 3 products are glycine, phosphate, and thioredoxin....

: sarcosine reductase
Sarcosine reductase
In enzymology, a sarcosine reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are acetyl phosphate, methylamine, and thioredoxin disulfide, whereas its 3 products are N-methylglycine, phosphate, and thioredoxin....

: betaine reductase
Betaine reductase
In enzymology, a betaine reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are acetyl phosphate, trimethylamine, and thioredoxin disulfide, whereas its 3 products are N,N,N-trimethylglycine, phosphate, and thioredoxin.This enzyme belongs to the family of...


EC 1.97.1

: chlorate reductase
Chlorate reductase
In enzymology, a chlorate reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are AH2 and chlorate, whereas its 3 products are A, H2O, and chlorite....

: pyrogallol hydroxytransferase
Pyrogallol hydroxytransferase
In enzymology, a pyrogallol hydroxytransferase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene , whereas its two products are 1,3,5-trihydroxybenzene and 1,2,3,5-tetrahydroxybenzene.This enzyme...

: sulfur reductase
Sulfur reductase
In enzymology, a sulfur reductase is an enzyme that catalyzes the chemical reaction of reduction of elemental sulfur or polysulfide to hydrogen sulfide....

: (formate-C-acetyltransferase)-activating enzyme
(formate-C-acetyltransferase)-activating enzyme
In enzymology, a [formate-C-acetyltransferase]-activating enzyme is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are S-adenosyl-L-methionine, dihydroflavodoxin, and formate C-acetyltransferase-glycine, whereas its 4 products are 5'-deoxyadenosine, L-methionine,...

: now *EC 1.20.4.1: now *EC 1.20.99.1: now *EC 1.20.4.2: tetrachloroethene reductive dehalogenase
Tetrachloroethene reductive dehalogenase
In enzymology, a tetrachloroethene reductive dehalogenase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are trichloroethene, chloride, and acceptor, whereas its two products are tetrachloroethene and reduced acceptor....

: selenate reductase
Selenate reductase
In enzymology, a selenate reductase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are selenite, H2O, and acceptor, whereas its two products are selenate and reduced acceptor....

: thyroxine 5'-deiodinase: thyroxine 5-deiodinase

EC 1.99.1 Hydroxylases (now covered by EC 1.14)

: deleted, now *EC 1.14.14.1: deleted, now *EC 1.14.16.1: deleted: deleted: deleted, now *EC 1.14.13.9: deleted: deleted, now *EC 1.14.15.4: deleted: deleted, now *EC 1.14.99.9: deleted: deleted, now *EC 1.14.99.10: deleted: deleted, covered by *EC 1.14.99.7 and *EC 5.4.99.7: deleted, now *EC 1.13.11.27

EC 1.99.2 Oxygenases (now covered by EC 1.13)

: deleted, now *EC 1.13.11.12: deleted, now *EC 1.13.11.1: deleted, now *EC 1.13.11.3: deleted, now *EC 1.13.11.4: deleted, now *EC 1.13.11.5: deleted, now *EC 1.13.99.1
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