Renilla-luciferin 2-monooxygenase
Encyclopedia
In enzymology, a Renilla-luciferin 2-monooxygenase is an enzyme
that catalyzes
the chemical reaction
Thus, the two substrates
of this enzyme are Renilla luciferin and O2
, whereas its 3 products
are oxidized Renilla luciferin, CO2
, and hn
.
This enzyme belongs to the family of oxidoreductase
s, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen (internal monooxygenases o internal mixed-function oxidases). The systematic name of this enzyme class is Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating). Other names in common use include Renilla-type luciferase, aequorin, and luciferase (Renilla luciferin).
have been solved for this class of enzymes, with PDB
accession codes , , , , , , and .
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that catalyzes
Catalysis
Catalysis is the change in rate of a chemical reaction due to the participation of a substance called a catalyst. Unlike other reagents that participate in the chemical reaction, a catalyst is not consumed by the reaction itself. A catalyst may participate in multiple chemical transformations....
the chemical reaction
Chemical reaction
A chemical reaction is a process that leads to the transformation of one set of chemical substances to another. Chemical reactions can be either spontaneous, requiring no input of energy, or non-spontaneous, typically following the input of some type of energy, such as heat, light or electricity...
- Renilla luciferin + O2
oxidized Renilla luciferin + CO2 + hnu
Thus, the two substrates
Substrate (biochemistry)
In biochemistry, a substrate is a molecule upon which an enzyme acts. Enzymes catalyze chemical reactions involving the substrate. In the case of a single substrate, the substrate binds with the enzyme active site, and an enzyme-substrate complex is formed. The substrate is transformed into one or...
of this enzyme are Renilla luciferin and O2
Oxygen
Oxygen is the element with atomic number 8 and represented by the symbol O. Its name derives from the Greek roots ὀξύς and -γενής , because at the time of naming, it was mistakenly thought that all acids required oxygen in their composition...
, whereas its 3 products
Product (chemistry)
Product are formed during chemical reactions as reagents are consumed. Products have lower energy than the reagents and are produced during the reaction according to the second law of thermodynamics. The released energy comes from changes in chemical bonds between atoms in reagent molecules and...
are oxidized Renilla luciferin, CO2
Carbon dioxide
Carbon dioxide is a naturally occurring chemical compound composed of two oxygen atoms covalently bonded to a single carbon atom...
, and hn
HN
HN may refer to:* Hacker News, a popular tech news site* Hanoi, Vietnam* Hawk Nelson, a Christian punk band* Heavylift Cargo Airlines' IATA airline designator* Herceg Novi, a town in Montenegro* Heilbronn, a city in Germany...
.
This enzyme belongs to the family of oxidoreductase
Oxidoreductase
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule to another...
s, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen (internal monooxygenases o internal mixed-function oxidases). The systematic name of this enzyme class is Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating). Other names in common use include Renilla-type luciferase, aequorin, and luciferase (Renilla luciferin).
Structural studies
As of late 2007, 7 structuresTertiary structure
In biochemistry and molecular biology, the tertiary structure of a protein or any other macromolecule is its three-dimensional structure, as defined by the atomic coordinates.-Relationship to primary structure:...
have been solved for this class of enzymes, with PDB
Protein Data Bank
The Protein Data Bank is a repository for the 3-D structural data of large biological molecules, such as proteins and nucleic acids....
accession codes , , , , , , and .