Lonchocarpus laxiflorus
Encyclopedia
Lonchocarpus laxiflorus is a species of legume in the Fabaceae
Fabaceae
The Fabaceae or Leguminosae, commonly known as the legume, pea, or bean family, is a large and economically important family of flowering plants. The group is the third largest land plant family, behind only the Orchidaceae and Asteraceae, with 730 genera and over 19,400 species...

 family. The tree grows to 4-8 meters in height, has grey or yellowish bark and compound leaves. New leaves are accompanied by purple flowers on multi-branched panicle
Panicle
A panicle is a compound raceme, a loose, much-branched indeterminate inflorescence with pedicellate flowers attached along the secondary branches; in other words, a branched cluster of flowers in which the branches are racemes....

s. The fruit is a glabrous papery pod, usually containing one seed. L. laxiflorus is distributed across much of Africa
Africa
Africa is the world's second largest and second most populous continent, after Asia. At about 30.2 million km² including adjacent islands, it covers 6% of the Earth's total surface area and 20.4% of the total land area...

 south of the Sahara
Sahara
The Sahara is the world's second largest desert, after Antarctica. At over , it covers most of Northern Africa, making it almost as large as Europe or the United States. The Sahara stretches from the Red Sea, including parts of the Mediterranean coasts, to the outskirts of the Atlantic Ocean...

, from Senegal
Senegal
Senegal , officially the Republic of Senegal , is a country in western Africa. It owes its name to the Sénégal River that borders it to the east and north...

 south to Angola
Angola
Angola, officially the Republic of Angola , is a country in south-central Africa bordered by Namibia on the south, the Democratic Republic of the Congo on the north, and Zambia on the east; its west coast is on the Atlantic Ocean with Luanda as its capital city...

 and east to Sudan
Sudan
Sudan , officially the Republic of the Sudan , is a country in North Africa, sometimes considered part of the Middle East politically. It is bordered by Egypt to the north, the Red Sea to the northeast, Eritrea and Ethiopia to the east, South Sudan to the south, the Central African Republic to the...

, Ethiopia
Ethiopia
Ethiopia , officially known as the Federal Democratic Republic of Ethiopia, is a country located in the Horn of Africa. It is the second-most populous nation in Africa, with over 82 million inhabitants, and the tenth-largest by area, occupying 1,100,000 km2...

 and Kenya
Kenya
Kenya , officially known as the Republic of Kenya, is a country in East Africa that lies on the equator, with the Indian Ocean to its south-east...

. It is found in savanna
Savanna
A savanna, or savannah, is a grassland ecosystem characterized by the trees being sufficiently small or widely spaced so that the canopy does not close. The open canopy allows sufficient light to reach the ground to support an unbroken herbaceous layer consisting primarily of C4 grasses.Some...

 woodlands and dry forested areas, particularly fringing forest near water sources.

Human use

L. laxiflorus is used across its range for traditional medicine
Traditional medicine
Traditional medicine comprises unscientific knowledge systems that developed over generations within various societies before the era of modern medicine...

. These uses include:
  • Benin
    Benin
    Benin , officially the Republic of Benin, is a country in West Africa. It borders Togo to the west, Nigeria to the east and Burkina Faso and Niger to the north. Its small southern coastline on the Bight of Benin is where a majority of the population is located...

    : A decoction of roots with Cymbopogan schoenanthus and Hymenocardia acidia the leaves of Vitex simplicifolia is used in vapor baths and administered orally to treat mental illness
    Mental illness
    A mental disorder or mental illness is a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which is not a part of normal development or culture. Such a disorder may consist of a combination of affective, behavioural,...

    . A decoction of leafy twigs with those of Byrsocarpus coccineus is drunk and used as a lotion to treat dermatitis
    Dermatitis
    -Etymology:Dermatitis derives from Greek derma "skin" + -itis "inflammation" and genetic disorder.-Terminology:There are several different types of dermatitis. The different kinds usually have in common an allergic reaction to specific allergens. The term may describe eczema, which is also called...

    . The powder of calcined roots is rubbed on the forehead to treat headache
    Headache
    A headache or cephalalgia is pain anywhere in the region of the head or neck. It can be a symptom of a number of different conditions of the head and neck. The brain tissue itself is not sensitive to pain because it lacks pain receptors. Rather, the pain is caused by disturbance of the...

    .
  • Central African Republic
    Central African Republic
    The Central African Republic , is a landlocked country in Central Africa. It borders Chad in the north, Sudan in the north east, South Sudan in the east, the Democratic Republic of the Congo and the Republic of the Congo in the south, and Cameroon in the west. The CAR covers a land area of about ,...

    : The Lissongo macerate the root to make a drink to treat intestinal worms.
  • North Gambia: Used as medication for "women's disorders"
  • Kenya
    Kenya
    Kenya , officially known as the Republic of Kenya, is a country in East Africa that lies on the equator, with the Indian Ocean to its south-east...

    : Root infusion
    Infusion
    An infusion is the outcome of steeping plants with desired chemical compounds or flavors in water or oil.-History:The first recorded use of essential oils was in the 10th or 11th century by the Persian polymath Avicenna, possibly in The Canon of Medicine.-Preparation techniques:An infusion is very...

     used to treat back pain
    Back pain
    Back pain is pain felt in the back that usually originates from the muscles, nerves, bones, joints or other structures in the spine.The pain can often be divided into neck pain, upper back pain, lower back pain or tailbone pain...

     and paralysis
    Paralysis
    Paralysis is loss of muscle function for one or more muscles. Paralysis can be accompanied by a loss of feeling in the affected area if there is sensory damage as well as motor. A study conducted by the Christopher & Dana Reeve Foundation, suggests that about 1 in 50 people have been diagnosed...

  • North Nigeria
    Nigeria
    Nigeria , officially the Federal Republic of Nigeria, is a federal constitutional republic comprising 36 states and its Federal Capital Territory, Abuja. The country is located in West Africa and shares land borders with the Republic of Benin in the west, Chad and Cameroon in the east, and Niger in...

    : Medicine made from leaves used for foot ulcers. Bark and roots used for jaundice
    Jaundice
    Jaundice is a yellowish pigmentation of the skin, the conjunctival membranes over the sclerae , and other mucous membranes caused by hyperbilirubinemia . This hyperbilirubinemia subsequently causes increased levels of bilirubin in the extracellular fluid...

     and as a tonic. The bark is also used for an anthelmintic
    Anthelmintic
    Anthelmintics or antihelminthics are drugs that expel parasitic worms from the body, by either stunning or killing them. They may also be called vermifuges or vermicides .-Pharmaceutical classes:...

    .
  • Senegal
    Senegal
    Senegal , officially the Republic of Senegal , is a country in western Africa. It owes its name to the Sénégal River that borders it to the east and north...

    : Bambara practitioners uses the roots to treat leprosy
    Leprosy
    Leprosy or Hansen's disease is a chronic disease caused by the bacteria Mycobacterium leprae and Mycobacterium lepromatosis. Named after physician Gerhard Armauer Hansen, leprosy is primarily a granulomatous disease of the peripheral nerves and mucosa of the upper respiratory tract; skin lesions...

     and intestinal disorders.
  • Togo
    Togo
    Togo, officially the Togolese Republic , is a country in West Africa bordered by Ghana to the west, Benin to the east and Burkina Faso to the north. It extends south to the Gulf of Guinea, on which the capital Lomé is located. Togo covers an area of approximately with a population of approximately...

    : Root bark mixed with that of Stereospermum kunthianum and elephant
    Elephant
    Elephants are large land mammals in two extant genera of the family Elephantidae: Elephas and Loxodonta, with the third genus Mammuthus extinct...

     excrement to fumigate against leprosy
    Leprosy
    Leprosy or Hansen's disease is a chronic disease caused by the bacteria Mycobacterium leprae and Mycobacterium lepromatosis. Named after physician Gerhard Armauer Hansen, leprosy is primarily a granulomatous disease of the peripheral nerves and mucosa of the upper respiratory tract; skin lesions...

     or, alternatively, a root concoction mixed with that of young Parkia biglobosa
    Parkia biglobosa
    Parkia biglobosa or Néré is a tree of the genus Parkia in the family Fabaceae. In West Africa, its fruits are fermented to a condiment called "soumbala" or "dawa-dawa"....

    and Vitellaria paradoxa is drunk
  • Northern Uganda
    Uganda
    Uganda , officially the Republic of Uganda, is a landlocked country in East Africa. Uganda is also known as the "Pearl of Africa". It is bordered on the east by Kenya, on the north by South Sudan, on the west by the Democratic Republic of the Congo, on the southwest by Rwanda, and on the south by...

    : In traditional Acholi culture, before a war, an old woman of the chief's clan had to bless the weapons of the warriors by sprinkling them with a branch of L. laxiflorus dipped in water and millet
    Millet
    The millets are a group of small-seeded species of cereal crops or grains, widely grown around the world for food and fodder. They do not form a taxonomic group, but rather a functional or agronomic one. Their essential similarities are that they are small-seeded grasses grown in difficult...

     flour. In nearby Apac District
    Apac District
    Apac District is a district in Northern Uganda. Like most other Ugandan districts, it is named after its 'chief town', Apac, where the district headquarters are located...

    , water sprinkled with L. laxiflorus branches around a home was used to ward off evil spirits.

Other uses of L. laxiflorus include applying a lotion with a decoction to the skin to treat venereal disease, constipation
Constipation
Constipation refers to bowel movements that are infrequent or hard to pass. Constipation is a common cause of painful defecation...

 in children, skin diseases, sterility
Infertility
Infertility primarily refers to the biological inability of a person to contribute to conception. Infertility may also refer to the state of a woman who is unable to carry a pregnancy to full term...

 (insufficient semen
Semen
Semen is an organic fluid, also known as seminal fluid, that may contain spermatozoa. It is secreted by the gonads and other sexual organs of male or hermaphroditic animals and can fertilize female ova...

).

Chemistry and toxicology

L. laxiflorus has been little studied, though many Lonchocarpus
Lonchocarpus
Lonchocarpus is a plant genus in the legume family . The species are called lancepods due to their fruit resembling an ornate lance tip or a few beads on a string....

species contain rotenoid
Rotenoid
Rotenoids are naturally occurring substances containing a cis-fused tetrahydrochromeno[3,4-b]chromene nucleus. Rotenoids are related to the isoflavones....

s, tannin
Tannin
A tannin is an astringent, bitter plant polyphenolic compound that binds to and precipitates proteins and various other organic compounds including amino acids and alkaloids.The term tannin refers to the use of...

s, flavonoid
Flavonoid
Flavonoids , are a class of plant secondary metabolites....

s, and isoflavonoid
Isoflavonoid
Isoflavonoids are a class of flavonoid polyphenolic compounds. They are biologically active compounds, such as phytoestrogens, produced by pea family plants.Isoflavonoids are derived from the flavonoid biosynthesis pathway via liquiritigenin or naringenin....

s. One study extracted several new compounds from the bark: two isoflavanes (lonchocarpane and laxiflorane) and two pterocarpanes (philonopterane and 9-O-methyl derivative).

Nothing specific is known about the toxicology
Toxicology
Toxicology is a branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals on living organisms...

 of L. laxiflorus, though several Lonchocarpus species are known to cause severe poison
Poison
In the context of biology, poisons are substances that can cause disturbances to organisms, usually by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by an organism....

ing symptoms.
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