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1421 The first patent is issued by the Republic of Florence.[Terence, Kealey. ''The Economic Laws of Scientific Research.'' 1996.]
1790 United States Patent system established.
1790 Inventor Samuel Hopkins becomes the first to be issued a U.S. patent (for an improved method of making potash).
1794 Eli Whitney is granted a patent for the cotton gin.
1809 Mary Kies is the first American woman to be awarded a patent.
1829 In the United States, William Burt obtains the first patent for a writing mechanism. (See typewriter)
1830 Barthélemy Thimonnier is granted a patent (#7454) for a sewing machine in France. It chains stitches at 200/minute.
1836 Samuel Colt receives an American patent for the Colt revolver.
1839 William Otis receives a patent for the steam shovel.
1844 Charles Goodyear receives a patent for vulcanization, a process to strengthen rubber.
1874 Levi Strauss and Jacob Davis receive a US patent for blue jeans with copper rivets
1887 Herman Hollerith receives a patent for his punch card calculator.
1892 Thomas Edison receives a patent for a two-way telegraph.
1893 Thomas Edison receives two U.S. patents. The first is for a "Cut Out for Incandescent Electric Lamps" and another for a "Stop Device" (No. 491,992-3). Also No. 492,150 for "Process of Coating Conductors for Incandescent Lamps."
1895 George B. Selden is granted the first U.S. patent for an automobile.
1931 Thomas Edison submits his last patent application.
1937 Wallace H. Carothers receives a patent for nylon.
1960 March 22 — Arthur Leonard Schawlow & Charles Hard Townes receive the first patent for a laser.
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