Special Research Units
Encyclopedia
Special Research Units were covert medical experiment units of the Imperial Japanese Army
Imperial Japanese Army
-Foundation:During the Meiji Restoration, the military forces loyal to the Emperor were samurai drawn primarily from the loyalist feudal domains of Satsuma and Chōshū...

which conducted biological warfare
Biological warfare
Biological warfare is the use of biological toxins or infectious agents such as bacteria, viruses, and fungi with intent to kill or incapacitate humans, animals or plants as an act of war...

 research and development through human experimentation
Human experimentation
Human subject research includes experiments and observational studies. Human subjects are commonly participants in research on basic biology, clinical medicine, nursing, psychology, and all other social sciences. Humans have been participants in research since the earliest studies...

 during the Second Sino-Japanese War
Second Sino-Japanese War
The Second Sino-Japanese War was a military conflict fought primarily between the Republic of China and the Empire of Japan. From 1937 to 1941, China fought Japan with some economic help from Germany , the Soviet Union and the United States...

 (1937 - 1945) and World War II
World War II
World War II, or the Second World War , was a global conflict lasting from 1939 to 1945, involving most of the world's nations—including all of the great powers—eventually forming two opposing military alliances: the Allies and the Axis...

. These units are responsible for some of the most notorious war crimes carried out by Japanese personnel
Japanese war crimes
Japanese war crimes occurred during the period of Japanese imperialism, primarily during the Second Sino-Japanese War and World War II. Some of the incidents have also been described as an Asian Holocaust and Japanese war atrocities...

. Initially set up as a political and ideological section of the Kempeitai
Kempeitai
The was the military police arm of the Imperial Japanese Army from 1881 to 1945. It was not an English-style military police, but a French-style gendarmerie...

 military police
Military police
Military police are police organisations connected with, or part of, the military of a state. The word can have different meanings in different countries, and may refer to:...

 of pre-Pacific War
Pacific War
The Pacific War, also sometimes called the Asia-Pacific War refers broadly to the parts of World War II that took place in the Pacific Ocean, its islands, and in East Asia, then called the Far East...

 Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...

, they were meant to counter the ideological or political influence of Japan's enemies, and to reinforce the ideology of military units.

In military campaigns, the Japanese army used biological weapons on Chinese soldiers and civilians. This employment was largely viewed as ineffective, due to inefficient delivery systems. However, information has surfaced in the last decade, which alleges a more active Japanese usage. For example, firsthand accounts testify the Japanese infected civilians through the distribution of plague-infested foodstuffs, such as dumplings and vegetables. There are also reports of contaminated water supplies. Such estimates report over 580,000 victims, largely due to plague and cholera outbreaks. In addition, repeated seasonal outbreaks after the conclusion of the war bring the death toll much higher. During Changde chemical weapon attack attacks, the Japanese also employed biological warfare
Biological warfare
Biological warfare is the use of biological toxins or infectious agents such as bacteria, viruses, and fungi with intent to kill or incapacitate humans, animals or plants as an act of war...

 by intentionally spreading cholera
Cholera
Cholera is an infection of the small intestine that is caused by the bacterium Vibrio cholerae. The main symptoms are profuse watery diarrhea and vomiting. Transmission occurs primarily by drinking or eating water or food that has been contaminated by the diarrhea of an infected person or the feces...

, dysentery
Dysentery
Dysentery is an inflammatory disorder of the intestine, especially of the colon, that results in severe diarrhea containing mucus and/or blood in the faeces with fever and abdominal pain. If left untreated, dysentery can be fatal.There are differences between dysentery and normal bloody diarrhoea...

, typhoid, bubonic plague
Bubonic plague
Plague is a deadly infectious disease that is caused by the enterobacteria Yersinia pestis, named after the French-Swiss bacteriologist Alexandre Yersin. Primarily carried by rodents and spread to humans via fleas, the disease is notorious throughout history, due to the unrivaled scale of death...

, and anthrax
Anthrax
Anthrax is an acute disease caused by the bacterium Bacillus anthracis. Most forms of the disease are lethal, and it affects both humans and other animals...

. Other battles include Kaimingye germ weapon attack
Kaimingye germ weapon attack
The Kaimingjie germ weapon attack was a Japanese biological warfare bacterial germ strike against Kaimingjie, an area of the port of Ningbo in the Chinese province of Zhejiang in October 1940, during the Second Sino-Japanese War....

.

Related activities

  • Running prisoner of war
    Prisoner of war
    A prisoner of war or enemy prisoner of war is a person, whether civilian or combatant, who is held in custody by an enemy power during or immediately after an armed conflict...

     and forced labor and special camps (The Kempeitai apparently provided guards for several 'human experimentation' units which housed 'difficult' prisoners, including Chinese
    China
    Chinese civilization may refer to:* China for more general discussion of the country.* Chinese culture* Greater China, the transnational community of ethnic Chinese.* History of China* Sinosphere, the area historically affected by Chinese culture...

    , Russian, American and other nationalities as well as some Japanese
    Japanese people
    The are an ethnic group originating in the Japanese archipelago and are the predominant ethnic group of Japan. Worldwide, approximately 130 million people are of Japanese descent; of these, approximately 127 million are residents of Japan. People of Japanese ancestry who live in other countries...

     criminals from the Japanese mainlands . sent to Unit 100
    Unit 100
    Unit 100 was a secret Imperial Japanese Army facility that focused on the development of biological weapons during World War II. It was operated by the Kempeitai, the Japanese military police...

     and Unit 731
    Unit 731
    was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that undertook lethal human experimentation during the Second Sino-Japanese War and World War II. It was responsible for some of the most notorious war crimes carried out by Japanese...

    .
  • Provision of "comfort" women
    Comfort women
    The term "comfort women" was a euphemism used to describe women forced into sexual slavery by the Japanese military during World War II.Estimates vary as to how many women were involved, with numbers ranging from as low as 20,000 from some Japanese scholars to as high as 410,000 from some Chinese...

     (jugun ianfu) for the "comfort houses" (These were brothel
    Brothel
    Brothels are business establishments where patrons can engage in sexual activities with prostitutes. Brothels are known under a variety of names, including bordello, cathouse, knocking shop, whorehouse, strumpet house, sporting house, house of ill repute, house of prostitution, and bawdy house...

    s maintained by the IJA for the use of its troops. Originally Japanese volunteers were used but as these became rare or limited to the use of officers, many Chinese, Korean, Taiwanese, and some European women were kidnapped and placed in these facilities to be "used" by members of Japan's military. The Kempeitai also regulated the accommodation facilities of the brothels, checked the identities of their customers, and controlled the violence and drunkenness within.)

The Units

Unit 731
Unit 731
was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that undertook lethal human experimentation during the Second Sino-Japanese War and World War II. It was responsible for some of the most notorious war crimes carried out by Japanese...

 was the headquarters of many subsidiary units used by the Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...

ese to research biological warfare; other units included
  • Unit 100
    Unit 100
    Unit 100 was a secret Imperial Japanese Army facility that focused on the development of biological weapons during World War II. It was operated by the Kempeitai, the Japanese military police...

     (Shenyang
    Shenyang
    Shenyang , or Mukden , is the capital and largest city of Liaoning Province in Northeast China. Currently holding sub-provincial administrative status, the city was once known as Shengjing or Fengtianfu...

    )
  • Unit 200
    Unit 200
    Unit 200 was a secret military medical unit of the Imperial Japanese Army that researched biological warfare and other topics through human experimentation during the Second Sino-Japanese War and World War II era. This unit was associated directly with Unit 731, and worked mainly in plague...

     (Manchuria
    Manchuria
    Manchuria is a historical name given to a large geographic region in northeast Asia. Depending on the definition of its extent, Manchuria usually falls entirely within the People's Republic of China, or is sometimes divided between China and Russia. The region is commonly referred to as Northeast...

    )
  • Unit 516
    Unit 516
    Unit 516 was a top secret Japanese chemical weapons facility, operated by the Kempeitai, in Qiqihar, Manchukuo. The name Unit 516 was a code name of the Unit....

     (Qiqihar
    Qiqihar
    - Subdivisions :Qiqihar is divided into 16 divisions: 7 districts , 8 counties and 1 county-level city .-Economy:...

    )
  • Unit 543
    Unit 543
    Unit 543 was a secret Imperial Japanese Army facility at Hailar that focused on the development of biological weapons during World War II. It was operated by the Kempeitai, the Japanese military police. -See also:*Japanese war crimes...

     (Hailar)
  • Unit 731
    Unit 731
    was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that undertook lethal human experimentation during the Second Sino-Japanese War and World War II. It was responsible for some of the most notorious war crimes carried out by Japanese...

     (Pingfang
    Pingfang
    Pingfang District is a district in the outskirts of Harbin, China . It was the headquarters of the Japanese Biological Warfare Unit 731 during the Japanese invasion of China and World War II. It had an airport, railway and dungeons...

    )
  • Unit 773
    Unit 773
    Unit 773 was a secret Imperial Japanese Army facility that focused on the development of biological weapons during World War II. It was operated by the Kempeitai, the Japanese military police, in Songo, China. -See also:*Japanese war crimes*Kantogun...

     (Songo)
  • Unit Ei 1644
    Unit Ei 1644
    Unit Ei 1644 , also known as Unit 1644, was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that undertook lethal human experimentation during the Second Sino-Japanese War and World War II...

     (Nanjing
    Nanjing
    ' is the capital of Jiangsu province in China and has a prominent place in Chinese history and culture, having been the capital of China on several occasions...

    )
  • Unit 1855
    Unit 1855
    Unit 1855 Unit 1855 Unit 1855 (第一八五五部隊)was a secret Imperial Japanese Army facility that focused on the development of biological weapons during World War II. It was operated by the Kempeitai, the Japanese military police, in Nanjing.-See also:*Japanese war crimes...

     (Nanjing
    Nanjing
    ' is the capital of Jiangsu province in China and has a prominent place in Chinese history and culture, having been the capital of China on several occasions...

    )
  • Unit 2646
    Unit 2646
    Unit 2646 was a secret Imperial Japanese Army facility that focused on the development of biological weapons during World War II. It was operated by the Kempeitai, the Japanese military police in Hailar....

     or Unit 80 (Hailar)
  • Unit 8604
    Unit 8604
    Unit 8604 or Nami Unit was a secret military medical unit of the Imperial Japanese Army that researched biological warfare and other topics through human experimentation during the Second Sino-Japanese War and World War II era...

     or Nami Unit (Guangzhou
    Guangzhou
    Guangzhou , known historically as Canton or Kwangchow, is the capital and largest city of the Guangdong province in the People's Republic of China. Located in southern China on the Pearl River, about north-northwest of Hong Kong, Guangzhou is a key national transportation hub and trading port...

    )
  • Unit 9420
    Unit 9420
    Imperial Japanese ArmyFormed in 1942 to support the Japanese Southern Army, Unit 9420 or Oka Unit consisted of two units; the Umeoka Unit, which specialised in the plague, and the Kono Unit, which specialised in malaria....

     or Oka Unit (Singapore
    Singapore
    Singapore , officially the Republic of Singapore, is a Southeast Asian city-state off the southern tip of the Malay Peninsula, north of the equator. An island country made up of 63 islands, it is separated from Malaysia by the Straits of Johor to its north and from Indonesia's Riau Islands by the...

    )

Activities

A special project code-named Maruta used human beings for experiments. Test subjects were gathered from the surrounding population and were sometimes referred to euphemistically as . This term originated as a joke on the part of the staff because the official cover story for the facility given to the local authorities was that it was a lumber mill. The test subjects were selected to give a wide cross section of the population, and included common criminals, captured bandits and anti-Japanese partisans, political prisoner
Political prisoner
According to the Longman Dictionary of Contemporary English, a political prisoner is ‘someone who is in prison because they have opposed or criticized the government of their own country’....

s, and also people rounded up by the secret police
Secret police
Secret police are a police agency which operates in secrecy and beyond the law to protect the political power of an individual dictator or an authoritarian political regime....

 for alleged "suspicious activities" and included infants, the elderly, and pregnant women.

Vivisection

  • Prisoners of war were subjected to vivisection
    Vivisection
    Vivisection is defined as surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure...

     without anesthesia.
  • Vivisections were performed on prisoners after infecting them with various diseases. Scientists performed invasive surgery on prisoners, removing organs to study the effects of disease on the human body. These were conducted while the patients were alive because it was felt that the decomposition process would affect the results. The infected and vivisected prisoners included men, women, children, and infants.
  • Vivisections were also performed on pregnant women, sometimes impregnated by doctors, and the fetus
    Fetus
    A fetus is a developing mammal or other viviparous vertebrate after the embryonic stage and before birth.In humans, the fetal stage of prenatal development starts at the beginning of the 11th week in gestational age, which is the 9th week after fertilization.-Etymology and spelling variations:The...

     removed.
  • Prisoners had limbs amputated
    Amputation
    Amputation is the removal of a body extremity by trauma, prolonged constriction, or surgery. As a surgical measure, it is used to control pain or a disease process in the affected limb, such as malignancy or gangrene. In some cases, it is carried out on individuals as a preventative surgery for...

     in order to study blood loss.
  • Those limbs that were removed were sometimes re-attached to the opposite sides of the body.
  • Some prisoners' limb
    Limb (anatomy)
    A limb is a jointed, or prehensile , appendage of the human or other animal body....

    s were frozen and amputated, while others had limbs frozen then thawed to study the effects of the resultant untreated gangrene
    Gangrene
    Gangrene is a serious and potentially life-threatening condition that arises when a considerable mass of body tissue dies . This may occur after an injury or infection, or in people suffering from any chronic health problem affecting blood circulation. The primary cause of gangrene is reduced blood...

     and rotting.
  • Some prisoners had their stomach
    Stomach
    The stomach is a muscular, hollow, dilated part of the alimentary canal which functions as an important organ of the digestive tract in some animals, including vertebrates, echinoderms, insects , and molluscs. It is involved in the second phase of digestion, following mastication .The stomach is...

    s surgically removed and the esophagus
    Esophagus
    The esophagus is an organ in vertebrates which consists of a muscular tube through which food passes from the pharynx to the stomach. During swallowing, food passes from the mouth through the pharynx into the esophagus and travels via peristalsis to the stomach...

     reattached to the intestines.
  • Parts of the brain
    Brain
    The brain is the center of the nervous system in all vertebrate and most invertebrate animals—only a few primitive invertebrates such as sponges, jellyfish, sea squirts and starfishes do not have one. It is located in the head, usually close to primary sensory apparatus such as vision, hearing,...

    , lungs, liver
    Liver
    The liver is a vital organ present in vertebrates and some other animals. It has a wide range of functions, including detoxification, protein synthesis, and production of biochemicals necessary for digestion...

    , etc. were removed from some prisoners.


In 2007, Doctor Ken Yuasa testified to the Japan Times that "I was afraid during my first vivisection, but the second time around, it was much easier. By the third time, I was willing to do it." He believes at least 1,000 persons, including surgeons, were involved in vivisections over mainland China.

Weapons testing

  • Human targets were used to test grenade
    Grenade
    A grenade is a small explosive device that is projected a safe distance away by its user. Soldiers called grenadiers specialize in the use of grenades. The term hand grenade refers any grenade designed to be hand thrown. Grenade Launchers are firearms designed to fire explosive projectile grenades...

    s positioned at various distances and in different positions.
  • Flame throwers were tested on humans.
  • Humans were tied to stakes and used as targets to test germ-releasing bombs, chemical weapons and explosive bomb
    Bomb
    A bomb is any of a range of explosive weapons that only rely on the exothermic reaction of an explosive material to provide an extremely sudden and violent release of energy...

    s.

Germ warfare attacks

  • Prisoners were injected with inoculations of disease, disguised as vaccinations
    Vaccine
    A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe or its toxins...

    , to study their effects.
  • To study the effects of untreated venereal diseases, male and female prisoners were deliberately infected with syphilis
    Syphilis
    Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subspecies pallidum. The primary route of transmission is through sexual contact; however, it may also be transmitted from mother to fetus during pregnancy or at birth, resulting in congenital syphilis...

     and gonorrhea
    Gonorrhea
    Gonorrhea is a common sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae. The usual symptoms in men are burning with urination and penile discharge. Women, on the other hand, are asymptomatic half the time or have vaginal discharge and pelvic pain...

    , then studied.
  • Prisoners were infested with flea
    Flea
    Flea is the common name for insects of the order Siphonaptera which are wingless insects with mouthparts adapted for piercing skin and sucking blood...

    s in order to acquire large quantities of disease-carrying fleas for the purposes of studying the viability of germ warfare.
  • Plague
    Bubonic plague
    Plague is a deadly infectious disease that is caused by the enterobacteria Yersinia pestis, named after the French-Swiss bacteriologist Alexandre Yersin. Primarily carried by rodents and spread to humans via fleas, the disease is notorious throughout history, due to the unrivaled scale of death...

     fleas, infected clothing, and infected supplies encased in bombs were dropped on various targets. The resulting cholera
    Cholera
    Cholera is an infection of the small intestine that is caused by the bacterium Vibrio cholerae. The main symptoms are profuse watery diarrhea and vomiting. Transmission occurs primarily by drinking or eating water or food that has been contaminated by the diarrhea of an infected person or the feces...

    , anthrax
    Anthrax
    Anthrax is an acute disease caused by the bacterium Bacillus anthracis. Most forms of the disease are lethal, and it affects both humans and other animals...

    , and plague were estimated to have killed around 200,000 Chinese civilians.
  • Tularemia
    Tularemia
    Tularemia is a serious infectious disease caused by the bacterium Francisella tularensis. A Gram-negative, nonmotile coccobacillus, the bacterium has several subspecies with varying degrees of virulence. The most important of those is F...

     was tested on Chinese civilians.
  • Unit 731 and its affiliated units (Unit 1644, Unit 100, et cetera) were actively involved not only in research and development, but also in experimental deployment of epidemic-creating biowarfare weapons in assaults against the Chinese populace (both civilian and military) throughout World War II. Plague-infested fleas, bred in the laboratories of Unit 731 and Unit 1644, were spread by low-flying airplanes upon Chinese cities, coastal Ningbo
    Ningbo
    Ningbo is a seaport city of northeastern Zhejiang province, Eastern China. Holding sub-provincial administrative status, the municipality has a population of 7,605,700 inhabitants at the 2010 census whom 3,089,180 in the built up area made of 6 urban districts. It lies south of the Hangzhou Bay,...

     in 1940, and Changde
    Changde
    Changde is a city in the north of Hunan Province, China, with a population of 5,717,218 inhabitants at the 2010 census whom 1,232,182 in the built up area made of 2 urban districts .-History:...

    , Hunan
    Hunan
    ' is a province of South-Central China, located to the south of the middle reaches of the Yangtze River and south of Lake Dongting...

     Province, in 1941. This military aerial spraying killed thousands of people with bubonic plague
    Bubonic plague
    Plague is a deadly infectious disease that is caused by the enterobacteria Yersinia pestis, named after the French-Swiss bacteriologist Alexandre Yersin. Primarily carried by rodents and spread to humans via fleas, the disease is notorious throughout history, due to the unrivaled scale of death...

     epidemics.

Other experiments

Prisoners were subjected to other experiments such as:
  • being hung upside down to see how long it would take for them to choke to death.
  • having air injected into their arteries to determine the time until the onset of embolism
    Embolism
    In medicine, an embolism is the event of lodging of an embolus into a narrow capillary vessel of an arterial bed which causes a blockage in a distant part of the body.Embolization is...

    .
  • having horse urine
    Urine
    Urine is a typically sterile liquid by-product of the body that is secreted by the kidneys through a process called urination and excreted through the urethra. Cellular metabolism generates numerous by-products, many rich in nitrogen, that require elimination from the bloodstream...

     injected into their kidneys.
  • being deprived of food and water to determine the length of time until death.
  • being placed into high-pressure chambers until death.
  • being exposed to extreme temperatures and developed frostbite
    Frostbite
    Frostbite is the medical condition where localized damage is caused to skin and other tissues due to extreme cold. Frostbite is most likely to happen in body parts farthest from the heart and those with large exposed areas...

     to determine how long humans could survive with such an affliction, and to determine the effects of rotting and gangrene on human flesh.
  • having experiments performed upon prisoners to determine the relationship between temperature, burns, and human survival.
  • being placed into centrifuges and spun until dead.
  • having animal blood injected and the effects studied.
  • being exposed to lethal doses of x-ray
    X-ray
    X-radiation is a form of electromagnetic radiation. X-rays have a wavelength in the range of 0.01 to 10 nanometers, corresponding to frequencies in the range 30 petahertz to 30 exahertz and energies in the range 120 eV to 120 keV. They are shorter in wavelength than UV rays and longer than gamma...

     radiation
    Radiation
    In physics, radiation is a process in which energetic particles or energetic waves travel through a medium or space. There are two distinct types of radiation; ionizing and non-ionizing...

    .
  • having various chemical weapons tested on prisoners inside gas chambers.
  • being injected with sea water to determine if it could be a substitute for saline
    Saline (medicine)
    In medicine, saline is a general term referring to a sterile solution of sodium chloride in water but is only sterile when it is to be placed intravenously, otherwise, a saline solution is a salt water solution...

    .
  • being given a large amount of water to drink and the effect observed
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