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Oxygen Therapy

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Oxygen therapy



 
 
Oxygen therapy is the administration of oxygen
Oxygen

Oxygen no O2 produced; 2) O2 produced, but absorbed in oceans & seabed rock; 3) O2 starts to gas out of the oceans, but is absorbed by land surfaces and formation of ozone layer; 4-5) O2 sinks filled and the gas accumulates]]...
 as a therapeutic modality. Oxygen therapy benefits the patient by increasing the supply of oxygen to the lungs and thereby increasing the availability of oxygen to the body tissues.

Appropriate levels of oxygen are vital to support cell
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
 respiration. High blood and tissue levels of oxygen can be helpful or damaging, depending on circumstances.






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Oxygen therapy is the administration of oxygen
Oxygen

Oxygen no O2 produced; 2) O2 produced, but absorbed in oceans & seabed rock; 3) O2 starts to gas out of the oceans, but is absorbed by land surfaces and formation of ozone layer; 4-5) O2 sinks filled and the gas accumulates]]...
 as a therapeutic modality. Oxygen therapy benefits the patient by increasing the supply of oxygen to the lungs and thereby increasing the availability of oxygen to the body tissues.

Appropriate levels of oxygen are vital to support cell
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
 respiration. High blood and tissue levels of oxygen can be helpful or damaging, depending on circumstances. Hyperbaric oxygen therapy
Hyperbaric oxygen therapy

Hyperbaric medicine, also known as hyperbaric oxygen therapy , is the medical use of oxygen at a level higher than atmospheric pressure....
 is the use of high levels of oxygen for treatment of specific diseases. High levels of oxygen given to infants causes blindness
Blindness

Blindness is the condition of lacking visual perception due to physiological or neurological factors.Various scales have been developed to describe the extent of vision loss and define "blindness." Total blindness is the complete lack of form and visual light perception and is clinically recorded as "NLP," an abbreviation for "no ligh...
 by promoting overgrowth of new blood vessels in the eye obstructing sight. This is Retinopathy of prematurity
Retinopathy of prematurity

Retinopathy of prematurity , previously known as retrolental fibroplasia , is a disease of the eye that affects prematurely born babies. It is thought to be caused by disorganized growth of retinal blood vessels which may result in scarring and retinal detachment....
 (ROP). Administration of high levels of oxygen in patients with severe emphysema and high blood carbon dioxide
Carbon dioxide

Carbon dioxide is a chemical compound composed of two oxygen atoms covalent bond to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state....
 reduces respiratory drive, which can precipitate respiratory failure and death.

Oxygen first aid specifically refers to the use of oxygen in a first aid setting. Oxygen will assist patients with myocardial infarction
Myocardial infarction

Myocardial infarction , commonly known as a heart attack, occurs when the Blood flow to part of the heart is interrupted. This is most commonly due to occlusion of a coronary artery following the rupture of a Vulnerable plaque, which is an unstable collection of lipids and white blood cells in the wall of an artery....
 and hypoxia
Hypoxia (medical)

Hypoxia is a Pathology condition in which the body as a whole or a region of the body is deprived of adequate oxygen supply. Variations in arterial oxygen concentrations can be part of the normal physiology, for example, during strenuous physical exercise....
 (low blood oxygen levels). Care needs to be exercised in patients with chronic obstructive pulmonary disease, especially in those known to retain carbon dioxide
Carbon dioxide

Carbon dioxide is a chemical compound composed of two oxygen atoms covalent bond to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state....
 (type II respiratory failure) who lose their respiratory drive and accumulate carbon dioxide if administered oxygen in moderate concentration. However the risk of the loss of respiratory drive are far outweighed by the risks of withholding emergency oxygen, and therefore emergency administration of oxygen is never contraindicated.

Home or domiciliary oxygen therapy

This refers to the administration of oxygen as ongoing therapy, either continuously or intermittently. Most commonly patients on home oxygen therapy have severe chronic obstructive pulmonary disease caused by smoking
Smoking

Smoking is a practice where a substance, most commonly tobacco, is burned and the smoke tasted or inhaled. This is primarily done as a form of recreational drug use, as combustion releases the active substances in drugs such as nicotine and makes them available for absorption through the lungs....
. High concentration (approaching 100%) oxygen is used as home therapy to abort cluster headache
Cluster headache

Cluster headache, nicknamed "suicide headache", is a neurological disease that involves, as its most prominent feature, an immense degree of pain....
 attacks, due to its vaso-constrictive effects. It is indicated in COPD
COPD

Chronic obstructive pulmonary disease is a group of diseases of the lungs in which the airways become narrowed. This leads to a limitation of the flow of air to and from the lungs causing shortness of breath....
 patients with PaO2 = 55mmHg or SaO2 = 88% and has been shown in a Medical Research Council
Medical Research Council (UK)

The Medical Research Council is a United Kingdom organisation dedicated to "improve human health through world-class medical research"....
 study to increase survival.

Oxygen sources and delivery

There are three typical sources of oxygen used therapeutically:

  1. Liquid oxygen
    Liquid oxygen

    Liquid oxygen is a form of the element oxygen. It has a pale blue color and is strongly paramagnetism. Liquid oxygen has a density of 1.141 g/cm? and is moderately cryogenics ...
     is contained in thermally insulating tanks
    Oxygen tank

    An oxygen tank is a storage vessel for oxygen, which is either held under pressure in gas cylinders or as liquid oxygen in a cryogenic storage tank....
    . The liquid has to boil changing into a gas for breathing. Large tanks are used by hospitals. Small tanks can be used domestically. Liquid oxygen tanks are refilled by liquid oxygen suppliers.
  2. Cylinders
    Gas cylinder

    A gas cylinder or Storage tank is a pressure vessel used to store gases at high pressure. Gases stored this way are called bottled gases....
     contain compressed gaseous oxygen. Small cylinders are used for first aid and for home oxygen patients when mobility is required. Cylinders are refilled by a gas supplier.
  3. Oxygen concentrator
    Oxygen concentrator

    An oxygen concentrator is a machine used to provide oxygen therapy to a patient at substantially higher concentrations than those of ambient air, used as an alternative to tanks of compressed oxygen....
    s are electrically powered devices which remove nitrogen
    Nitrogen

    Nitrogen is a chemical element that has the symbol N and atomic number 7 and atomic mass 14.00674?. Elemental nitrogen is a colorless, odorless, tasteless and mostly inert diatomic gas at standard conditions, constituting 78% by volume of Earth's atmosphere....
     from air
    AIR

    Air is the part of Earth's atmosphere that humans breath and as such Air .Air may also refer to:...
    . They are most commonly used in a domestic situation, because they do not need refilling. However, a number of manufacturers have introduced portable
    Portable

    Portable may refer to:* Portable building, a manufactured structure that is built off site and moved in upon completion of site and utility work...
     oxygen concentrators. These have replaced the need to use liquid or gas cylinders for mobility for many patients. Portable Oxygen Concentrators allow patients to freely travel without the need of gas or liquid. The FAA has approved portable oxygen concentrators for the use on many commercial airlines. Most major airlines allow the three major portable oxygen concentrators; it is necessary to check in advance if a particular brand or model is permitted on a particular airline. These can typically use AC, DC, or battery power. Some portable concentrators have only pulse or demand flow capabilities, while continuous flow portables are available. Pulse or demand flow is similar to the way an oxygen conserving device delivers oxygen from liquid oxygen or a gas cylinder only during inhalation, but on a concentrator, the oxygen made in between pulses is stored for the next pulse. Where a conserving device can make a liquid or gas container last longer, pulse or demand settings on oxygen concentrators can make a certain flow appear as a higher effective flow, or reduce power consumption and/or extend battery life.


First aid kits have been produced that create oxygen gas as the result of a chemical reaction
Chemical reaction

A chemical reaction is a process that always results in the interconversion of chemical substances. The substance or substances initially involved in a chemical reaction are called reactants....
 between lightweight or widely available substances such as sodium percarbonate
Sodium percarbonate

Sodium percarbonate is a white crystalline water-soluble chemical compound of sodium carbonate and hydrogen peroxide.It is an oxidizing agent and ingredient in a number of home and laundry detergent products....
 and water
Water

Water is a common chemical substance that is essential for the survival of all known forms of life. In typical usage, water refers only to its liquid form or States of matter, but the substance also has a solid state, ice, and a gaseous state, water vapor or steam....
, although the rate and duration of oxygen supply is not high.

Oxygen is most often delivered as continuous gaseous flow, measured in litre
Litre

The litre or liter is a unit of volume. There are two official symbols: the Latin letter L in lower and upper case . The lower case L is often written as a cursive l to avoid confusion with the number 1 in antiqua fonts....
s per minute (lpm).

Administration

Various devices are used for administration of oxygen.

Low-Flow Devices

Low-flow systems deliver oxygen at flows that are less than the patient's inspiratory flowrate (ie, the delivered oxygen is diluted with room air) and, thus, the oxygen concentration inhaled may be low or high, depending on the specific device and the patient's inspiratory flowrate.

  1. The nasal cannula
    Nasal cannula

    The nasal cannula is a device used to deliver supplemental oxygen to a patient or person in need of extra oxygen. This device consists of a plastic tube which fits behind the ears, and a set of two prongs which are placed in the nostrils....
     (NC) is a thin tube with two small nozzles that protrude into the patients nostrils. It can only comfortably provide oxygen at low flow rates, 0.25-6 litres per minute (LPM), delivering a concentration of 24-40%. Flow rates greater than 4 liters per minute can cause discomfort and dry out the nasal passages and should also be used with a humidifcation system.
  2. The simple face mask
    Simple face mask

    The simple face mask is a basic disposable mask, made of clear plastic, to provide oxygen therapy for patients who are experiencing conditions such as chest pain , dizziness, and minor hemorrhages....
     (SFM) is a basic mask used for non-life-threatening conditions but which may progress in time, such as chest pain (possible heart attacks), dizziness, and minor hemorrhages. It is often set to deliver oxygen between 5-15 LPM. The final oxygen concentration delivered by this device is dependent upon the amount of room air that mixes with the oxygen the patient breathes. The general oxygen concentration is between 35% and 50%


  1. The Partial rebreathing mask is a simple mask with a reservoir bag. Oxygen flow should always be supplied to maintain the reservior bag at least one third to one half full on inspiration, usually 5-15 LPM. At a flow of 6-10 L/min the system can provide 40-70% oxygen.


High-Flow Devices

High-flow systems deliver a prescribed gas mixture -- either high or low FDO2 at flowrates that exceed patient demand.

  1. The non-rebreather mask
    Non-rebreather mask

    A non-rebreather mask, or NRB, is a device used in medical emergency that require oxygen therapy. An NRB requires that the patient can breathe unassisted, but unlike a nasal cannula, the NRB allows for the delivery of higher concentrations of oxygen....
     (NRB) is similar to the partial rebreathing mask except it has a series of one-way valves. One valve is placed between the bag and the mask to prevent exhaled air from returning to the bag. There should be a minimum flow of 10 L/min. The delivered FIO2 of this system is 60-80%, depending on the oxygen flow and breathing pattern.,


  1. Air-entrainment masks, also known as Venturi masks, can accurately deliver predetermined oxygen concentration to the trachea up to 40%. Jet-mixing masks rated at 35% or higher usually however do not deliver flowrates adequate to meet the inspiratory flowrates of adults in respiratory distress. Aerosol masks, tracheostomy collars, T-tube adapters, and face tents can be used with high-flow supplemental oxygen systems. A continuous aerosol generator or large-volume reservoir humidifier can humidify the gas flow. Some aerosol generators however, cannot provide adequate flows at high oxygen concentrations.


Filtered Oxygen Masks

Filtered oxygen masks have the ability to prevent exhaled, potentially infectious particles from being released into the surrounding environment. These masks are normally of a closed design such that leaks are minimized and breathing of room air is controlled through a series of one-way valves. Filtration of exhaled breaths is accomplished either by placing a filter on the exhalation port, or through an integral filter that is part of the mask itself. These masks first became popular in the Toronto (Canada) healthcare community during the 2003 SARS Crisis. SARS was identified as being respiratory based and it was determined that conventional oxygen therapy devices were not designed for the containment of exhaled particles., , Common practices of having suspected patients wear a surgical mask was confounded by the use of standard oxygen therapy equipment. In 2003, the HiOx80 oxygen mask was released for sale. The HiOx80 mask is a closed design mask that allows a filter to be placed on the exhalation port. Several new designs have emerged in the global healthcare community for the containment and filtration of potentially infectious particles. Other designs include the ISO-O2 oxygen mask,the Flo2Max oxygen mask, and the O-Mask. The use of oxygen masks that are capable of filtering exhaled particles is gradually becoming a recommended practice for pandemic preparation in many jurisdictions.

Because filtered oxygen masks use a closed design that minimizes or eliminates inadvertent exposure to room air, delivered oxygen concentrations to the patient have been found to be higher than conventional non-rebreather masks, approaching 99% using adequate oxygen flows. Because all exhaled particles are contained within the mask, nebulized medications are also prevented from being released into the surrounding atmosphere, decreasing the occupational exposure to healthcare staff and other patients.

Resuscitation/Specialized Devices

  1. The bag-valve-mask (BVM) is used for patients in critical condition who are either breathing extremely inefficiently, or not breathing at all (respiratory arrest). An oxygen reservoir bag is attached to a central cylindrical bag, attached to a valved mask that administers almost 100% concentration oxygen at 8-15 lpm. The central bag is squeezed manually to deliver a "breath" to the patient, or assist them in inspiration by overcoming airway resistance or thoracic constriction. This is the standard administration method for acute respiratory distress or respiratory arrest.
    Oxymask
    # The pocket mask
    Pocket mask

    A pocket mask, or pocket face mask or CPR mask, is a device used to safely deliver artificial respiration during a cardiac arrest or respiratory arrest....
     is a small device that can be carried on one's person. It is used for the same patients who the BVM is indicated for, but instead of delivering breaths by squeezing a reservoir, the care provider must exhale into the mask. Exhaled air from the provider can provide up to 16% oxygen to the patient, or higher if used with supplemental oxygen.
  2. The anaesthetic machine
    Anaesthetic machine

    The anaesthetic machine is used by anesthesiologists to support the administration of anaesthesia. The most common type of anaesthetic machine in use in the developed world is the continuous-flow anaesthetic machine, which is designed to provide an accurate and continuous supply of medical gases , mixed with an accurate concentration...
     is a device used during anesthesia that allows a variable amount of oxygen to be delivered, along with other gases including air
    AIR

    Air is the part of Earth's atmosphere that humans breath and as such Air .Air may also refer to:...
    , nitrous oxide
    Nitrous oxide

    Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula Nitrogen2Oxygen. At room temperature, it is a colorless Flammability gas, with a pleasant, slightly sweet odor and taste....
     and inhalational anaesthetic
    Inhalational anaesthetic

    Inhalational anaesthetics are gas or vapours possessing anaesthetic qualities. The agents of significant contemporary interest include the volatile anaesthetics and the gases ethylene, nitrous oxide and xenon....
    s.
  3. Aviator type and other specialized tight fitting oxygen mask
    Oxygen mask

    An oxygen mask provides a method to transfer breathing oxygen gas from a storage tank to the lungs. Oxygen masks may cover the nose and mouth or the entire face ....
    s are used in hyperbaric oxygen chambers and to provide oxygen to carbon monoxide
    Carbon monoxide

    Carbon monoxide, with the chemical formula CO, is a colorless and odorless, tasteless, yet highly toxic gas. Its molecules consist of one carbon atom covalent bond to one oxygen atom....
     victims.


Related devices

  1. A pressure regulator
    Pressure regulator

    A pressure regulator is a valve that automatically cuts off the flow of a liquid or gas at a certain pressure. Regulators are used to allow high-pressure fluid supply lines or tanks to be reduced to safe and/or usable pressures for various applications....
     is used to control the high pressure of oxygen delivered from a cylinder to a low pressure controllable by the flowmeter.
  2. A flowmeter is used to control and indicate the flow of oxygen. Typiclal flow range is 0-15 lpm.
  3. A nebulizer
    Nebulizer

    In medicine, a nebulizer is a device used to administer medication to people in the form of a mist inhaled into the lungs. It is commonly used in treating cystic fibrosis, asthma, and other respiratory diseases....
     can be used deliver nebulizable drugs such as albuterol or epinephrine
    Epinephrine

    Epinephrine is a hormone and neurotransmitter.Epinephrine increases the "fight or flight" response of the Sympathetic nervous system of the autonomic nervous system....
     into the airways by creating a vapor-mist from the liquid form of the drug. Nebulizers are also commonly used with room air in the home with an electric air pump.


Negative effects

Although most EMS
Emergency medical services

Emergency medical services are a branch of Emergency services dedicated to providing out-of-hospital Acute and/or transport to definitive care, to patients with illnesses and injuries which the patient, or the medical practitioner, believes constitutes a medical emergency....
 jurisdictions hold that oxygen should not be withheld from any patient, there are certain situations in which oxygen therapy can have a negative impact on a patient’s condition.

Oxygen has vasoconstrictive
Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, particularly the large arteries, arterioles and veins....
 effects on the circulatory system, reducing peripheral circulation and was once thought to potentially increase the effects of stroke
Stroke

A stroke is the rapidly developing loss of brain function due to a disturbance in the blood supply to the brain. According to the National Stroke Association, a "stroke" occurs when a blood clot blocks and artery or a blood vessel breaks, interrupting blood flow to an area of the brain....
. However, when additional oxygen is given to the patient, additional oxygen is dissolved in the plasma according to Henry's Law
Henry's law

In chemistry, Henry's law is one of the gas laws, formulated by William Henry in 1803. It states that:An equivalent way of stating the law is that the solubility of a gas in a liquid is proportional to the pressure of that gas above the liquid....
. This allows a compensating change to occur and the dissolved oxygen in plasma supports embarrassed (oxygen-starved) neurons, reduces inflammation and post-stroke cerebral edema. Since 1990, hyperbaric oxygen therapy has been used in the treatments of stroke on a worldwide basis. In rare instances, hyperbaric oxygen therapy patients have had seizures. However, because of the afformentioned Henry's Law effect of extra available dissolved oxygen to neurons, there is usually no negative sequel to the event. Such seizures are thought to be caused by hypoglycemia
Hypoglycemia

Hypoglycaemia or hypoglycemia is the medical term for a Pathology state produced by a lower than normal level of Blood glucose. The term hypoglycemia literally means "under-sweet blood" ....
 and the risk can be eradicated or reduced by carefully monitoring the patient's nutritional intake prior to oxygen treatment.

Some jurisdictions require that oxygen should not be given to children or people suffering from certain long-term lung conditions by first-responders without medical consultation.

Oxygen first aid has been used as an emergency treatment for diving
Scuba diving

SCUBA diving is Underwater diving, or taking part in another activity, while using a scuba set. By carrying a source of breathing gas , the scuba diver is able to stay underwater longer than with the simple breath-holding techniques used in snorkeling and free-diving, and is not hindered by air lines to a remote air source....
 injuries for years. The success of recompression therapy as well as a decrease in the number of recompression treatments required has been shown if first aid oxygen is given within four hours after surfacing. There are suggestions that oxygen administration may not be the most effective measure for the treatment of DCI/DCS and that Heliox
Heliox

Heliox is a breathing gas composed of a mixture of helium and oxygen .Heliox has been used medically since the 1930s, and although the medical community adopted it initially to alleviate symptoms of upper airway obstruction, its range of medical uses has since expanded greatly, mostly because of the low density of the gas....
 may be a better alternative. Recompression in a hyperbaric chamber with the patient breathing 100% oxygen is the standard hospital and military medical response to decompression illness
Decompression illness

Decompression Illness is a term generally used to describe illness after a decrease in the ambient pressure that a body is exposed to. Decompression Illness is usually experienced by divers, but it is not limited to diving in water....
 and decompression sickness
Decompression sickness

'Decompression sickness' , 'the diver?s disease', 'the bends', 'caisson disease' is the name given to a variety of symptoms suffered by a person exposed to a decrease in the pressure around the body....
.

Oxygen should never be given to a patient who is suffering from paraquat poisoning
Paraquat

Paraquat is the trade name for N,N-dimethyl-4,4'-bipyridinium dichloride, one of the most widely used herbicides in the world....
 unless they are suffering from severe respiratory distress or respiratory arrest, as this can increase the toxicity. (Paraquat poisoning is rare - for example 200 deaths globally from 1958-1978)

Oxygen therapy while on aircraft

In the United States
United States

The United States of America is a Federal government constitutional republic comprising U.S. state and a federal district. The country is situated mostly in central North America, where its Contiguous United States and Washington, D.C., the Capital districts and territories, lie between the Pacific Ocean and Atlantic Oceans, Borders of the U...
, most airlines restrict the devices allowed on board aircraft
Aircraft

An aircraft is a vehicle which is able to flight by being supported by the air, or in general, the atmosphere, of a planet. Examples include balloons, airplanes and helicopters....
. As a result passengers are restricted in what devices they can use. Some airlines will provide cylinders for passengers with an associated fee. Other airlines allow passengers to carry on approved portable concentrators. However the lists of approved devices varies by airline so passengers need to check with any airline they are planning to fly on. Passengers are generally not allowed to carry on their own cylinders. In all cases, passengers need to notify the airline in advance of their equipment.

See also


  • Nebulizer
    Nebulizer

    In medicine, a nebulizer is a device used to administer medication to people in the form of a mist inhaled into the lungs. It is commonly used in treating cystic fibrosis, asthma, and other respiratory diseases....
  • Mechanical ventilation
    Mechanical ventilation

    In medicine, mechanical ventilation is a method to mechanically assist or replace spontaneous respiration .Mechanical ventilation is typically used after an invasive intubation, a procedure wherein an endotracheal tube or tracheostomy tube is inserted into the airway....
  • Hyperbaric oxygen therapy
    Hyperbaric oxygen therapy

    Hyperbaric medicine, also known as hyperbaric oxygen therapy , is the medical use of oxygen at a level higher than atmospheric pressure....
  • Oxygen bar
    Oxygen bar

    An oxygen bar is an establishment, or part of one, that sells oxygen for recreational use. Individual flavored scents may be added to enhance the experience....
  • Emergency Medical Services
    Emergency medical services

    Emergency medical services are a branch of Emergency services dedicated to providing out-of-hospital Acute and/or transport to definitive care, to patients with illnesses and injuries which the patient, or the medical practitioner, believes constitutes a medical emergency....
  • Respiratory Therapist
  • Oxygen tent
    Oxygen tent

    An oxygen tent consists in a canopy placed over the head and shoulders or over the entire body of a patient to provide oxygen at a higher level than normal....


External links

  • Article contains useful background information.
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