1503 King James IV of Scotland marries Margaret Tudor, daughter of King Henry VII of England at Holyrood Abbey, Edinburgh, Scotland.
1565 The widowed Mary, Queen of Scots, marries Henry Stuart, Lord Darnley, Duke of Albany, at Holyrood Palace in Edinburgh, Scotland.
1566 David Rizzio, private secretary to Mary, Queen of Scots, is murdered in the Palace of Holyroodhouse, Edinburgh, Scotland.
1567 An explosion destroys the Kirk o' Field house in Edinburgh, Scotland. The second husband of Mary, Queen of Scots, Lord Darnley is found strangled, in what many believe to be an assassination.
1638 The Scottish National Covenant is signed in Edinburgh.
1808 The organizational meeting that led to the creation of the Wernerian Natural History Society, a former Scottish learned society, is held in Edinburgh.
1808 The inaugural meeting of the Wernerian Natural History Society, a former Scottish learned society, is held in Edinburgh.
1843 The Disruption in Edinburgh of the Free Church of Scotland from the Church of Scotland.
1871 The first international rugby football match, England v. Scotland, is played in Edinburgh at Raeburn Place.
1958 Subscriber Trunk Dialling (STD) is inaugurated in the UK by Queen Elizabeth II when she speaks to the Lord Provost in a call from Bristol to Edinburgh.
1964 Scotland's Forth Road Bridge near Edinburgh officially opens.
1999 The Scottish Parliament is officially opened by Queen Elizabeth on the day that legislative powers are officially transferred from the old Scottish Office in London to the new devolved Scottish Executive in Edinburgh.