List of animals that have been cloned
Encyclopedia
This is a list of animals that have been cloned
in alphabetical order.
One significant aspect of this list is documenting the transition from early concerns that animal cloning procedures might be limited to a few species, that cloned animals might be physiologically abnormal, or cloning might lack utility for society.
Carp
Chinese embryologist Tong Dizhou
successfully inserted the DNA from a male Asian carp
into the egg of a female Asian carp to create the first fish clone in 1963. In 1973 Dizhou inserted Asian carp DNA into a European crucian carp
to create the first interspecies clone.
Cat
Cattle
Dog
Frog
In 1958, John Gurdon
, then at Oxford University, explained that he had successfully cloned a frog. He did this by using intact nuclei
from somatic cells from a Xenopus
tadpole. This was an important extension of work of Briggs and King in 1952 on transplanting nuclei from embryonic blastula
cells
Gaur
A species of wild cattle, the first endangered species to be cloned. In 2001 at the Trans Ova Genetics in Sioux Center, Iowa, USA, a cloned Gaur was born from a surrogate domestic cow mother. However, the calf died within 48 hours.
Goat
Horse
Mice
Mule
Pig
Pyrenean ibex
In 2009, one clone was born alive, but died seven minutes later, due to physical defects in the lungs. The Pyrenean Ibex became the first taxon ever to come back from extinction, for a period of seven minutes in January 2009.
Water Buffalo
The world's first water buffalo was cloned either in Beijing China in 2005 or New Delhi, India in 2009 "Samrupa", the world's first cloned buffalo calf, which died a week later from a lung infection.
Wolf
Cloning
Cloning in biology is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria, insects or plants reproduce asexually. Cloning in biotechnology refers to processes used to create copies of DNA fragments , cells , or...
in alphabetical order.
One significant aspect of this list is documenting the transition from early concerns that animal cloning procedures might be limited to a few species, that cloned animals might be physiologically abnormal, or cloning might lack utility for society.
CarpCarpCarp are various species of oily freshwater fish of the family Cyprinidae, a very large group of fish native to Europe and Asia. The cypriniformes are traditionally grouped with the Characiformes, Siluriformes and Gymnotiformes to create the superorder Ostariophysi, since these groups have certain...
Chinese embryologist Tong DizhouTong Dizhou
Tong Dizhou was a Chinese embryologist remembered for his contributions to the field of cloning. He was the former vice president of Chinese Academy of Science-Biography:...
successfully inserted the DNA from a male Asian carp
Asian carp
Many species of heavy-bodied cyprinid fish are collectively known in the United States as Asian carp. Cyprinids from the subcontinent [for example, catla and mrigal ] are not included in this classification, and are known collectively as "Indian carp".Eight Asian carp have been substantially...
into the egg of a female Asian carp to create the first fish clone in 1963. In 1973 Dizhou inserted Asian carp DNA into a European crucian carp
Crucian carp
The crucian carp is a member of the family Cyprinidae, which includes many other fish, such as the common carp, or the smaller minnows. They inhabit lakes, ponds, and slow-moving rivers throughout Europe and Asia. The crucian is a medium-sized cyprinid, which rarely exceeds a weight of over 3.3...
to create the first interspecies clone.
CatCatThe cat , also known as the domestic cat or housecat to distinguish it from other felids and felines, is a small, usually furry, domesticated, carnivorous mammal that is valued by humans for its companionship and for its ability to hunt vermin and household pests...
- In December 2001, scientists at Texas A&M UniversityTexas A&M UniversityTexas A&M University is a coeducational public research university located in College Station, Texas . It is the flagship institution of the Texas A&M University System. The sixth-largest university in the United States, A&M's enrollment for Fall 2011 was over 50,000 for the first time in school...
created the first cloned catCatThe cat , also known as the domestic cat or housecat to distinguish it from other felids and felines, is a small, usually furry, domesticated, carnivorous mammal that is valued by humans for its companionship and for its ability to hunt vermin and household pests...
, CC (CopyCatCC (cat)CC, for "CopyCat" or "Carbon Copy" , is a brown tabby and white domestic shorthair and the first cloned pet. CC's surrogate mother was a tabby, but her genetic donor, Rainbow, was a calico domestic shorthair...
). Even though CC is an exact copy of his host, they have different personalities; i.e. CC is shy and timid, his host on the other hand is playful and curious. - In 2004, the first commercially cloned cat, Little NickyLittle Nicky (cat)Little Nicky is the first commercially produced cat clone. He was produced from the DNA of a 17-year-old Maine Coon cat named Nicky who died in 2003...
, was created by Genetic Savings & Clone.
CattleCattleCattle are the most common type of large domesticated ungulates. They are a prominent modern member of the subfamily Bovinae, are the most widespread species of the genus Bos, and are most commonly classified collectively as Bos primigenius...
- First World cloned calf (Gene) was born on February 7, 1997 on American Breeders Service facilities in Deforest, Wisconsin. Later it was transferred and kept to Minnesota Zoo Education Center.
- A HolsteinHolsteinHolstein is the region between the rivers Elbe and Eider. It is part of Schleswig-Holstein, the northernmost state of Germany....
heifer named Amy was cloned by Dr. Xiangzhong (Jerry) Yang using ear skin cells from a high-merit cow named Aspen at the University of Connecticut on June 10, 1999, followed by three additional clones, Betty, Cathy and Daisy by July 7, 1999. - Second Chance, a Brahman bull was cloned from Chance, a beloved celebrity bull. Second Chance was born August 9, 1999 at Texas A&M University.
- Texas A&M University cloned a Black Angus bull named 86 Squared in 2000, after cells from his donor, Bull 86, had been frozen for 15 years. Both bulls exhibit a natural resistance to Brucellosis, Tuberculosis and other diseases which can be transferred in meat.
- Millie and Emma were two female Jersey cows cloned at the University of TennesseeUniversity of TennesseeThe University of Tennessee is a public land-grant university headquartered at Knoxville, Tennessee, United States...
in 2001. They were the first cows to be produced using standard cell-culturing techniques. - Pampa the first animal cloned in ArgentinaArgentinaArgentina , officially the Argentine Republic , is the second largest country in South America by land area, after Brazil. It is constituted as a federation of 23 provinces and an autonomous city, Buenos Aires...
by Biosidus (2002) - Ten more Jersey cows were cloned at the University of TennesseeUniversity of TennesseeThe University of Tennessee is a public land-grant university headquartered at Knoxville, Tennessee, United States...
. (females, 2002) - Bonyana and Tamina cloned calf in Royan Research Institute, Isfahan, IranIranIran , officially the Islamic Republic of Iran , is a country in Southern and Western Asia. The name "Iran" has been in use natively since the Sassanian era and came into use internationally in 1935, before which the country was known to the Western world as Persia...
in summer of 2009. - In 2010 the first Spanish Fighting Bull was cloned by Spanish scientists. -- see also Got (bull)Got (bull)Got is the name of the world's first cloned fighting bull who was born on Tuesday May 18 2010. He was cloned from another fighting bull named Vasito, and scientist are hoping that he displays similar fighting characteristics of his "father"...
(2009).
- Anatolian Grey bull (Efe) was cloned in Turkey in 2009 and cattle from the same breed (Ece, Ecem, Nilufer, Kiraz) by TUBITAK
- GARIMA- I: world's first buffalo calf through the “Hand guided Cloning Technique” was born on February 6, 2009 at NDRI, Karnal(India).
- GARIMA- II: NDRI, Karnal(India).
- Cloned male buffalo calf Shresth born on August 26, 2010 atNational Dairy Research Institute, Karnal, India-132001
DogDogThe domestic dog is a domesticated form of the gray wolf, a member of the Canidae family of the order Carnivora. The term is used for both feral and pet varieties. The dog may have been the first animal to be domesticated, and has been the most widely kept working, hunting, and companion animal in...
- South KoreaSouth KoreaThe Republic of Korea , , is a sovereign state in East Asia, located on the southern portion of the Korean Peninsula. It is neighbored by the People's Republic of China to the west, Japan to the east, North Korea to the north, and the East China Sea and Republic of China to the south...
n scientist Hwang Woo-SukHwang Woo-SukHwang Woo-suk is a South Korean veterinarian and researcher. He was a professor of theriogenology and biotechnology at Seoul National University who became infamous for fabricating a series of experiments, which appeared in high-profile journals, in the field of stem cell research...
cloned the first dogDogThe domestic dog is a domesticated form of the gray wolf, a member of the Canidae family of the order Carnivora. The term is used for both feral and pet varieties. The dog may have been the first animal to be domesticated, and has been the most widely kept working, hunting, and companion animal in...
, an afghan houndAfghan HoundThe Afghan Hound is one of the oldest sighthound dog breeds. Distinguished by its thick, fine, silky coat and its tail with a ring curl at the end, the breed acquired its unique features in the cold mountains of Afghanistan, where it was originally used to hunt hares and gazelles by coursing them....
named SnuppySnuppySnuppy is an Afghan hound, credited with being the world's first cloned dog. The puppy was created using the cell of an ear from an adult Afghan hound and involved 123 surrogate mothers, of which only three produced pups...
. Later in 2005 Hwang Woo-Suk was found to have fabricated evidence in stem cell research projects. This caused some to question the veracity of his other experiments, including Snuppy. In their investigation of Hwang Woo-Suk's publication, however, a team from SNU confirmed that Snuppy was a true clone of Tei, the DNA donor dog. South Korean scientists recently cloned 'sniffer' dogs. - BioArts International held a dog cloning contest where people would send in submissions about which dog was the most suited to be cloned. The winner was Trakr, a K-9 police dog who was a 9/11 hero.
- In summer 2011, South Korean researchers cloned a beagleBeagleThe Beagle is a breed of small to medium-sized dog. A member of the Hound Group, it is similar in appearance to the Foxhound, but smaller, with shorter legs and longer, softer ears. Beagles are scent hounds, developed primarily for tracking hare, rabbit, and other game...
dog named Tegon, which glowed in ultravioletUltravioletUltraviolet light is electromagnetic radiation with a wavelength shorter than that of visible light, but longer than X-rays, in the range 10 nm to 400 nm, and energies from 3 eV to 124 eV...
light
FrogFrogFrogs are amphibians in the order Anura , formerly referred to as Salientia . Most frogs are characterized by a short body, webbed digits , protruding eyes and the absence of a tail...
(tadpole)
In 1958, John GurdonJohn Gurdon
Sir John Bertrand Gurdon , FRS is a British developmental biologist. He is best known for his pioneering research in nuclear transplantation and cloning. He was recently awarded the Lasker Award.-Career:...
, then at Oxford University, explained that he had successfully cloned a frog. He did this by using intact nuclei
Cell nucleus
In cell biology, the nucleus is a membrane-enclosed organelle found in eukaryotic cells. It contains most of the cell's genetic material, organized as multiple long linear DNA molecules in complex with a large variety of proteins, such as histones, to form chromosomes. The genes within these...
from somatic cells from a Xenopus
Xenopus
Xenopus is a genus of highly aquatic frogs native to Sub-Saharan Africa. There are 19 species in the Xenopus genus...
tadpole. This was an important extension of work of Briggs and King in 1952 on transplanting nuclei from embryonic blastula
Blastula
The blastula is a hollow sphere of cells formed during an early stage of embryonic development in animals . The blastula is created when the zygote undergoes the cell division process known as cleavage. The blastula is preceded by the morula and is followed by the gastrula in the developmental...
cells
GaurGaurThe gaur , also called Indian bison, is a large bovine native to South Asia and Southeast Asia. The species is listed as vulnerable on the IUCN Red List since 1986 as the population decline in parts of the species' range is likely to be well over 70% over the last three generations...
A species of wild cattle, the first endangered species to be cloned. In 2001 at the Trans Ova Genetics in Sioux Center, Iowa, USA, a cloned Gaur was born from a surrogate domestic cow mother. However, the calf died within 48 hours.GoatGoatThe domestic goat is a subspecies of goat domesticated from the wild goat of southwest Asia and Eastern Europe. The goat is a member of the Bovidae family and is closely related to the sheep as both are in the goat-antelope subfamily Caprinae. There are over three hundred distinct breeds of...
- Downen TX 63 684 (nicknamed Megan) was cloned from a top producing Boer goatBoer goatThe Boer goat was developed inSouth Africa in the early 1900s for meat production. Their name is derived from the Dutch word "Boer" meaning farmer. The Boer goat was probably bred from the indigenous goats of the Namaqua Bushmen and the Fooku tribes, with some crossing of Indian and European...
born on March 29, 2001 at Texas A&M University. - The Middle East's first and the world's fifth cloned goat, 'Hanna', has been successfully born at Royan institute in Isfahan, Iran. The cloned goat was developed in the surrogate uterus of a black Bakhtiari goat for 147 days and was born, Wednesday, at 1:30 a.m. through a cesarean section. She is reported to be in a good health. Hanna, also known as R-CAP-C1, is completely distinguished from other goats because of its white and henna-like color. Iran's first cloned lamb, Royana, was born September 30, 2006 in Royan institute and was able to survive the post-natal complications common in cloned animals. Iranian researchers are looking to use cloned goats to produce the genetically modified animals required for manufacturing new recombinant medications.(April 2009) Isfahan, IranIranIran , officially the Islamic Republic of Iran , is a country in Southern and Western Asia. The name "Iran" has been in use natively since the Sassanian era and came into use internationally in 1935, before which the country was known to the Western world as Persia...
http://irannegah.com/Video.aspx?id=1110 at Irannegah.com
HorseHorseThe horse is one of two extant subspecies of Equus ferus, or the wild horse. It is a single-hooved mammal belonging to the taxonomic family Equidae. The horse has evolved over the past 45 to 55 million years from a small multi-toed creature into the large, single-toed animal of today...
- PrometeaPrometeaPrometea is a Haflinger foal, the first cloned horse and the first to be born from and carried by its cloning mother. Her birth was announced publicly on August 6, 2003. Born 36 kg after a natural delivery and a full-term pregnancy in Laboratory of Reproductive Technology, Cremona, Italy, Prometea...
, female, born May 2003, Italy - Pieraz, male, born February 2005, Italy
- Paris-Texas, male, born March 2005, USA
- Gemini, male, born September 2008, USA, clone of multiple recipient of "Horse of the Year" award for jumping Gem TwistGem TwistGem Twist was a world champion American Thoroughbred show jumping horse registered under the name Icey Twist. Bred by equestrian Frank Chapot, Gem Twist had an incredible career at the Grand Prix level...
- Saphir, male, born February 2010, USA, clone of show jumper SapphireSapphire (horse)"Sapphire" is a Holsteiner Warmblood show jumper gelding horse, born April 15, 1992. An Olympic competitor and 2003 Pan American Games Gold Medalist.- Career :...
MiceHouse mouseThe house mouse is a small rodent, a mouse, one of the most numerous species of the genus Mus.As a wild animal the house mouse mainly lives associated with humans, causing damage to crops and stored food....
- Possibly the first cloned mammals was a mouse (named "Masha") in 1986, in the Soviet UnionSoviet UnionThe Soviet Union , officially the Union of Soviet Socialist Republics , was a constitutionally socialist state that existed in Eurasia between 1922 and 1991....
. However, the cloning was done from an embryo cell, while the sheep Dolly in 1996 was cloned from an adult cell. - The first mouse from adult cells, CumulinaCumulinaCumulina , a mouse, was the first animal cloned from adult cells that survived to adulthood. She was cloned using the Honolulu technique developed by the Ryuzo Yanagimachi research group, 'Team Yana', at the former campus of the John A. Burns School of Medicine located at the University of...
, was born in 1997 at the University of Hawai'i at MānoaUniversity of Hawaii at ManoaThe University of Hawaii at Mānoa is a public, co-educational university and is the flagship campus of the greater University of Hawaii system...
in the laboratory of Ryuzo YanagimachiRyuzo Yanagimachihas made major contributions in understanding the process and mechanism of mammalian fertilization. He is a pioneer of assisted fertilization technologies such as in vitro fertilization and direct sperm injection into egg which are widely used today in human infertility clinics throughout the world...
using the Honolulu technique. - Over a dozen clones as of 2002.
MuleMuleA mule is the offspring of a male donkey and a female horse. Horses and donkeys are different species, with different numbers of chromosomes. Of the two F1 hybrids between these two species, a mule is easier to obtain than a hinny...
- Idaho GemIdaho GemThe mule Idaho Gem was the first equine and first cloned mule.He resulted from the collaboration of Dr. Gordon Woods and Dr. Dirk Vanderwall of the Northwest Equine Reproduction Laboratory at the University of Idaho and Dr. Ken White of Utah State University...
(male, May 2003) - Utah Pioneer (male, June 2003)
- Idaho Star (male, July 2003)
PigPigA pig is any of the animals in the genus Sus, within the Suidae family of even-toed ungulates. Pigs include the domestic pig, its ancestor the wild boar, and several other wild relatives...
- 5 Scottish PPL piglets (Millie, Alexis, Dotcom, Carrel, and Christa) (March 5, 2000)
- Xena (female, August 2000)
Pyrenean ibexPyrenean IbexThe Pyrenean Ibex is an ibex, one of the two extinct subspecies of Spanish Ibex. The subspecies once ranged across the Pyrenees in France and Spain and the surrounding area, including the Basque Country, Navarre, north Aragon and north Catalonia. A few hundred years ago they were numerous, but by...
In 2009, one clone was born alive, but died seven minutes later, due to physical defects in the lungs. The Pyrenean Ibex became the first taxon ever to come back from extinction, for a period of seven minutes in January 2009.Rhesus Monkey
- TetraTetra (monkey)Tetra is a Rhesus macaque that was created through a cloning technique called "embryo splitting". She is the first cloned primate, and was created by a team led by Professor Gerald Schatten of the Oregon National Primate Research Center....
(female, January 2000) by embryo splitting. - Cloned embryos (November 2007) by transfer of DNA from adult cells .
Sheep
- From early embryonic cells by Steen Willadsen (1986). Megan and Morag cloned from differentiated embryonic cells in June 1995.
- Dolly (1996–2003), first cloned mammal from somatic cells
- Polly and MollyPolly and MollyPolly and Molly , two ewes, were the first mammals to have been successfully cloned from an adult somatic cell and to be transgenic animals at the same time. This is not to be confused with Dolly the Sheep which was the first animal to be successfully cloned from an adult somatic cell where there...
(July 1997), first transgenic cloned mammal - Royana (2006) cloned in Royan Research institute in Isfahan, Iran.
- Oyalı http://www.haber7.com/haber.php?haber_id=281814 http://en.rian.ru/science/20071122/89073344.html and Zarifehttp://www.haber7.com/haber.php?haber_id=283561 were cloned in November 2007 in Istanbul UniversityIstanbul UniversityIstanbul University is a Turkish university located in Istanbul. The main campus is adjacent to Beyazıt Square.- Synopsis :A madrasa, a religious school, was established sometime in the 15th century after the Ottoman conquest of Constantinople. An institution of higher education named the...
in IstanbulIstanbulIstanbul , historically known as Byzantium and Constantinople , is the largest city of Turkey. Istanbul metropolitan province had 13.26 million people living in it as of December, 2010, which is 18% of Turkey's population and the 3rd largest metropolitan area in Europe after London and...
, TurkeyTurkeyTurkey , known officially as the Republic of Turkey , is a Eurasian country located in Western Asia and in East Thrace in Southeastern Europe...
.
Water BuffaloWater BuffaloThe water buffalo or domestic Asian water buffalo is a large bovine animal, frequently used as livestock in southern Asia, and also widely in South America, southern Europe, northern Africa, and elsewhere....
The world's first water buffalo was cloned either in Beijing China in 2005 or New Delhi, India in 2009 "Samrupa", the world's first cloned buffalo calf, which died a week later from a lung infection.WolfGray WolfThe gray wolf , also known as the wolf, is the largest extant wild member of the Canidae family...
- An endangered species of wolf cloned by Korean scientists including the controversial scientist Hwang Woo-SukHwang Woo-SukHwang Woo-suk is a South Korean veterinarian and researcher. He was a professor of theriogenology and biotechnology at Seoul National University who became infamous for fabricating a series of experiments, which appeared in high-profile journals, in the field of stem cell research...
- There are two cloned wolves in a zoo in Korea for public view, they are called Snuwolf and Snuwolffy which are names taken from the university in Korea, Seoul National University.