In human mitochondrial genetics

Human mitochondrial genetics

Human mitochondrial genetics is the study of the genetics of the DNA contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell....

, haplogroup E is a human mitochondrial DNA (mtDNA) haplogroup

Human mitochondrial DNA haplogroups

In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree...

 typical for the Malay Archipelago

Malay Archipelago

The Malay Archipelago refers to the archipelago between mainland Southeastern Asia and Australia. The name was derived from the anachronistic concept of a Malay race....

. It is a subgroup of haplogroup M9

Haplogroup M (mtDNA)

In human mitochondrial genetics, Haplogroup M is a human mitochondrial DNA haplogroup. An enormous haplogroup spanning all the continents, the macro-haplogroup M, like its sibling N, is a descendant of haplogroup L3....

.

Origin

After a point of view, it was arisen in Northeast Sundaland

Sundaland

Sundaland is a biogeographical region of Southeastern Asia which encompasses the areas of the Asian continental shelf that was exposed during the last ice age. It included the Malay Peninsula on the Asian mainland, as well as the large islands of Borneo, Java, and Sumatra and their surrounding...

 or around Sulawesi

Celebes Sea

The Celebes Sea of the western Pacific Ocean is bordered on the north by the Sulu Archipelago and Sulu Sea and Mindanao Island of the Philippines, on the east by the Sangihe Islands chain, on the south by Sulawesi, and on the west by Kalimantan in Indonesia...

 and Sulu

Sulu Sea

The Sulu Sea is a body of water in the southwestern area of the Philippines, separated from the South China Sea in the northwest by Palawan and from the Celebes Sea in the southeast by the Sulu Archipelago. Borneo is found to the southwest and Visayas to the northeast.Sulu Sea contains a number of...

 Seas. On the other hand, it might be related with the Austronesian languages

Austronesian languages

The Austronesian languages are a language family widely dispersed throughout the islands of Southeast Asia and the Pacific, with a few members spoken on continental Asia that are spoken by about 386 million people. It is on par with Indo-European, Niger-Congo, Afroasiatic and Uralic as one of the...

 expansion from Taiwan

Taiwan

Taiwan , also known, especially in the past, as Formosa , is the largest island of the same-named island group of East Asia in the western Pacific Ocean and located off the southeastern coast of mainland China. The island forms over 99% of the current territory of the Republic of China following...

 to Insulinde, indicating a common origin of the populations of insular Southeast Asia and suggesting a prevalence in the Taiwanese aboriginal gene pool

Gene pool

In population genetics, a gene pool is the complete set of unique alleles in a species or population.- Description :A large gene pool indicates extensive genetic diversity, which is associated with robust populations that can survive bouts of intense selection...

 (mainly E with B4, B5a, F1a, F3b and M7) of its initial late Pleistocene

Late Pleistocene

The Late Pleistocene is a stage of the Pleistocene Epoch. The beginning of the stage is defined by the base of the Eemian interglacial phase before the final glacial episode of the Pleistocene 126,000 ± 5,000 years ago. The end of the stage is defined exactly at 10,000 Carbon-14 years BP...

 settlers.

Distribution

Haplogroup E has a Southeast Asian distribution. Until now it has been detected in the Malay peninsula

Malay Peninsula

The Malay Peninsula or Thai-Malay Peninsula is a peninsula in Southeast Asia. The land mass runs approximately north-south and, at its terminus, is the southern-most point of the Asian mainland...

 populations and in the Sabah

Sabah

Sabah is one of 13 member states of Malaysia. It is located on the northern portion of the island of Borneo. It is the second largest state in the country after Sarawak, which it borders on its southwest. It also shares a border with the province of East Kalimantan of Indonesia in the south...

 of Borneo

Borneo

Borneo is the third largest island in the world and is located north of Java Island, Indonesia, at the geographic centre of Maritime Southeast Asia....

; and it is also present in coastal Papua New Guinea

Papua New Guinea

Papua New Guinea , officially the Independent State of Papua New Guinea, is a country in Oceania, occupying the eastern half of the island of New Guinea and numerous offshore islands...

 as well as in Taiwan

Taiwan

Taiwan , also known, especially in the past, as Formosa , is the largest island of the same-named island group of East Asia in the western Pacific Ocean and located off the southeastern coast of mainland China. The island forms over 99% of the current territory of the Republic of China following...

, in the Philippines

Philippines

The Philippines , officially known as the Republic of the Philippines , is a country in Southeast Asia in the western Pacific Ocean. To its north across the Luzon Strait lies Taiwan. West across the South China Sea sits Vietnam...

, and in some Pacific islands such as Guam

Guam

Guam is an organized, unincorporated territory of the United States located in the western Pacific Ocean. It is one of five U.S. territories with an established civilian government. Guam is listed as one of 16 Non-Self-Governing Territories by the Special Committee on Decolonization of the United...

.

Tree

This phylogenetic tree of haplogroup E subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation and subsequent published research.

• E
  • E1
    • E1a
      • E1a1
        • E1a1a
          • E1a1a1
      • E1a2
    • E1b
      • E1b1
  • E2
    • E2a
    • E2b
      • E2b1
      • E2b2

See also

• Genealogical DNA test
  Genealogical DNA test
  A genealogical DNA test examines the nucleotides at specific locations on a person's DNA for genetic genealogy purposes. The test results are not meant to have any informative medical value and do not determine specific genetic diseases or disorders ; they are intended only to give genealogical...
  
  
• Genetic Genealogy
  Genetic genealogy
  Genetic genealogy is the application of genetics to traditional genealogy. Genetic genealogy involves the use of genealogical DNA testing to determine the level of genetic relationship between individuals.-History:...
  
  
• Human mitochondrial genetics
  Human mitochondrial genetics
  Human mitochondrial genetics is the study of the genetics of the DNA contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell....
  
  
• Population Genetics
  Population genetics
  Population genetics is the study of allele frequency distribution and change under the influence of the four main evolutionary processes: natural selection, genetic drift, mutation and gene flow. It also takes into account the factors of recombination, population subdivision and population...
  
  
• Human mitochondrial DNA haplogroups
  Human mitochondrial DNA haplogroups
  In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree...
  
  

External links

• General
  • Ian Logan's Mitochondrial DNA Site
  • Mannis van Oven's Phylotree
• Haplogroup E

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