Artemisia argyi
Encyclopedia
Argyi wormwood, Artemisia argyi, is a herbaceous perennial plant with a creeping rhizome. It is native to China, Japan and the far east parts of the former Soviet Union. In Japan it is known as Gaiyou and in China as Ai Ye. It is used in herbal medicine for conditions of the liver, spleen and kidney.

Description

Argyi wormwood is an upright, greyish, herbaceous
Herbaceous plant
A herbaceous plant is a plant that has leaves and stems that die down at the end of the growing season to the soil level. They have no persistent woody stem above ground...

 perennial
Perennial plant
A perennial plant or simply perennial is a plant that lives for more than two years. The term is often used to differentiate a plant from shorter lived annuals and biennials. The term is sometimes misused by commercial gardeners or horticulturalists to describe only herbaceous perennials...

 about one metre tall, with short branches and a creeping rhizome
Rhizome
In botany and dendrology, a rhizome is a characteristically horizontal stem of a plant that is usually found underground, often sending out roots and shoots from its nodes...

. The stalked leaves
Leaf
A leaf is an organ of a vascular plant, as defined in botanical terms, and in particular in plant morphology. Foliage is a mass noun that refers to leaves as a feature of plants....

 are ovate, deeply divided and covered in small, oil-producing glands, pubescent above and densely white tomentose below. The lower leaves are about six centimetres long, bipinnate with wide lanceolate lobes and short teeth along the margins. The upper leaves are smaller and three-partite, and the bracteal leaves are simple, linear and lanceolate. The inflorescence
Inflorescence
An inflorescence is a group or cluster of flowers arranged on a stem that is composed of a main branch or a complicated arrangement of branches. Strictly, it is the part of the shoot of seed plants where flowers are formed and which is accordingly modified...

 is a narrow leafy panicle. The individual flowers are pale yellow, tubular, and clustered in spherical turned-down heads. The central flowers are bisexual while the marginal flowers are female. The petals are narrow and folded cylindrically and the bracts have a cobwebby pubescence. The whole plant is strongly aromatic.

Habitat

This wormwood is a xerophile
Xerophile
Xerophiles are extremophilic organisms that can grow and reproduce in conditions with a low availability of water, also known as water activity. Water activity is a measure of the amount of water within a substrate that an organism can use to support sexual growth. Xerophiles are often said to...

, growing on dry mountain slopes, steep river banks, the edges of oak woods, coastal scrub, wasteland and along road and railway verges. The plants do better and are more aromatic when they grow on poor dry soil.

Medicinal use

Wormwood leaves are gathered on a warm dry day in spring and summer when the plant is in flower and dried in the shade. In traditional Chinese medicine
Traditional Chinese medicine
Traditional Chinese Medicine refers to a broad range of medicine practices sharing common theoretical concepts which have been developed in China and are based on a tradition of more than 2,000 years, including various forms of herbal medicine, acupuncture, massage , exercise , and dietary therapy...

, they are considered to have bitter, pungent and warm properties and to be associated with the liver, spleen and kidney meridian
Meridian (Chinese medicine)
The meridian is a path through which the life-energy known as "qi" is believed to flow, in traditional Chinese medicine. There is no physically verifiable anatomical or histological basis for the existence of acupuncture points or meridians.- Main concepts :...

s. The leaves are used as an antiseptic, expectorant, febrifuge and styptic. The herb is considered to increase the blood supply to the pelvic region and stimulate menstruation
Menstruation
Menstruation is the shedding of the uterine lining . It occurs on a regular basis in sexually reproductive-age females of certain mammal species. This article focuses on human menstruation.-Overview:...

, help treat infertility
Infertility
Infertility primarily refers to the biological inability of a person to contribute to conception. Infertility may also refer to the state of a woman who is unable to carry a pregnancy to full term...

, dysmenorrhea
Dysmenorrhea
Dysmenorrhea is a gynecological medical condition of pain during menstruation that interferes with daily activities, as defined by ACOG and others. Still, dysmenorrhea is often defined simply as menstrual pain, or at least menstrual pain that is excessive...

, asthma
Asthma
Asthma is the common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction, and bronchospasm. Symptoms include wheezing, coughing, chest tightness, and shortness of breath...

 and cough
Cough
A cough is a sudden and often repetitively occurring reflex which helps to clear the large breathing passages from secretions, irritants, foreign particles and microbes...

s. Another use is in moxibustion
Moxibustion
Moxibustion is a traditional Chinese medicine therapy using moxa, or mugwort herb. It plays an important role in the traditional medical systems of China, Japan, Korea, Vietnam, Tibet, and Mongolia. Suppliers usually age the mugwort and grind it up to a fluff; practitioners burn the fluff or...

, a form of healing in which the herb is burned in cones or sticks or on the tip of an acupuncture
Acupuncture
Acupuncture is a type of alternative medicine that treats patients by insertion and manipulation of solid, generally thin needles in the body....

 needle.
Boiling water can be poured onto the ground up leaves and used in a decoction
Decoction
Decoction is a method of extraction, by boiling, of dissolved chemicals, or herbal or plant material, which may include stems, roots, bark and rhizomes. Decoction involves first mashing, and then boiling in water to extract oils, volatile organic compounds, and other chemical substances...

, alone or with other substances, and the fresh leaf can be crushed and blended and a juice extracted. A volatile oil can be extracted from the leaves and used in the treatment of asthma and bronchitis
Bronchitis
Acute bronchitis is an inflammation of the large bronchi in the lungs that is usually caused by viruses or bacteria and may last several days or weeks. Characteristic symptoms include cough, sputum production, and shortness of breath and wheezing related to the obstruction of the inflamed airways...

 for which purpose it is sprayed onto the back of the throat and brings rapid relief.
The leaves have an antibacterial action and have been shown to be effective against Staphylococcus aureus
Staphylococcus aureus
Staphylococcus aureus is a facultative anaerobic Gram-positive coccal bacterium. It is frequently found as part of the normal skin flora on the skin and nasal passages. It is estimated that 20% of the human population are long-term carriers of S. aureus. S. aureus is the most common species of...

, Bacillus dysenteriae
Bacillary dysentery
Bacillary dysentery is a type of dysentery, and is a severe form of shigellosis.Bacillary dysentery is associated with species of bacteria from the Enterobacteriaceae family. The term is usually restricted to Shigella infections....

, Bacillus subtilis
Bacillus subtilis
Bacillus subtilis, known also as the hay bacillus or grass bacillus, is a Gram-positive, catalase-positive bacterium commonly found in soil. A member of the genus Bacillus, B. subtilis is rod-shaped, and has the ability to form a tough, protective endospore, allowing the organism to tolerate...

, Bacillus typhi
Salmonella enterica enterica
Salmonella enterica enterica is a subspecies of Salmonella enterica, the rod shaped, flagellated, aerobic, Gram-negative bacterium. It is a member of the genus Salmonella. Many of the pathogenic serovars of the S...

, Escherichia coli
Escherichia coli
Escherichia coli is a Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms . Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in humans, and are occasionally responsible for product recalls...

and Pseudomonas
Pseudomonas
Pseudomonas is a genus of gammaproteobacteria, belonging to the family Pseudomonadaceae containing 191 validly described species.Recently, 16S rRNA sequence analysis has redefined the taxonomy of many bacterial species. As a result, the genus Pseudomonas includes strains formerly classified in the...

.

Research

  • Ninety six volatile constituents have been identified from the leaves of A. argyi and certain other species of wormwood including alpha-thujene
    Thujene
    Thujene is a natural organic compound classified as a monoterpene. It is found in the essential oils of a variety of plants, and contributes pungency to the flavor of some herbs such as Summer savory....

    , 1,8-cineole, camphor
    Camphor
    Camphor is a waxy, white or transparent solid with a strong, aromatic odor. It is a terpenoid with the chemical formula C10H16O. It is found in wood of the camphor laurel , a large evergreen tree found in Asia and also of Dryobalanops aromatica, a giant of the Bornean forests...

     and artemisia alcohol.
  • Nearly fifty volatile constituents have been identified from A. argyi flowers and it is suggested that therapeutic use of the flowers may be just as effective as using the leaves.
  • A methanol extract prepared from aerial parts of the plant strongly reduced the mutagen
    Mutagen
    In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level. As many mutations cause cancer, mutagens are therefore also likely to be carcinogens...

    icity of Salmonella typhimurium
    Salmonella enterica enterica
    Salmonella enterica enterica is a subspecies of Salmonella enterica, the rod shaped, flagellated, aerobic, Gram-negative bacterium. It is a member of the genus Salmonella. Many of the pathogenic serovars of the S...

    .
  • An extract of A. argyi was shown to have antifungal
    Antifungal
    * Antifungal medication, a medication used to treat fungal infection s such as athlete's foot , ringworm, candidiasis, etc.* Antifungal protein, a protein family* an adjective referring to a fungicide compound...

     activity against Botrytis cinerea
    Botrytis cinerea
    Botrytis cinerea is a necrotrophic fungus that affects many plant species, although its most notable hosts may be wine grapes. In viticulture, it is commonly known as botrytis bunch rot; in horticulture, it is usually called grey mould or gray mold.The fungus gives rise to two different kinds of...

    and Alternaria alternata
    Alternaria alternata
    Alternaria alternata has been recorded causing leaf spot and other diseases on over 380 host species. It is opportunistic pathogen on numerous hosts causing leaf spots, rots and blights on many plant parts...

    which cause deterioration of fruit and vegetables in storage.
  • Flavones isolated from an extra of the herb were shown to have an anti-tumour
    Tumor
    A tumor or tumour is commonly used as a synonym for a neoplasm that appears enlarged in size. Tumor is not synonymous with cancer...

    effect.
  • A study examined the clinical efficacy of moxibustion, analyzed the chemical compositions of the leaf of different strains of A. argyi, examined the best mode of delivery and how to enhance the therapeutic effects of this treatment.
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