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Panic attack

 

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Panic attack



 
 
Panic attacks are very sudden, discrete periods of intense anxiety, mounting physiological arousal, fear, stomach problems and discomfort that are associated with a variety of somatic
Somatic

The term somatic refers to cells of the body, rather than gametes . In humans, somatic cells contain two copies of each chromosome , whereas eggs and sperm only contain one copy of each chromosome ....
 and cognitive symptoms. The onset of these episodes is typically abrupt, and may have no obvious triggers. Although these episodes may appear random, they are a subset of an evolutionary response commonly referred to as fight or flight
Fight-or-flight response

'The 'fight-or-flight response', also called the fright, fight or flight response', 'hyperarousal' or the 'acute stress response', was first described by Walter Cannon in 1915....
 that occur out of context.






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Panic attacks are very sudden, discrete periods of intense anxiety, mounting physiological arousal, fear, stomach problems and discomfort that are associated with a variety of somatic
Somatic

The term somatic refers to cells of the body, rather than gametes . In humans, somatic cells contain two copies of each chromosome , whereas eggs and sperm only contain one copy of each chromosome ....
 and cognitive symptoms. The onset of these episodes is typically abrupt, and may have no obvious triggers. Although these episodes may appear random, they are a subset of an evolutionary response commonly referred to as fight or flight
Fight-or-flight response

'The 'fight-or-flight response', also called the fright, fight or flight response', 'hyperarousal' or the 'acute stress response', was first described by Walter Cannon in 1915....
 that occur out of context. This response floods the body with hormones, particularly epinephrine
Epinephrine

Epinephrine is a hormone and neurotransmitter.Epinephrine increases the "fight or flight" response of the Sympathetic nervous system of the autonomic nervous system....
 (adrenaline), that aid it in defending against harm. Experiencing a panic attack is said to be one of the most intensely frightening, upsetting and uncomfortable experiences of a person's life. According to the American Psychological Association
American Psychological Association

The American Psychological Association is a professional organization representing psychology in the United States, with around 148,000 members and an annual budget of around $70m....
 the symptoms of a panic attack commonly last approximately thirty minutes. However, panic attacks can be as short as 15 seconds, while sometimes panic attacks may form a cyclic series of episodes, lasting for an extended period, sometimes hours. Often those afflicted will experience significant anticipatory anxiety and limited symptom attack
Limited symptom attack

A Limited Symptom Attack , also referred to as a Limited Symptom Panic Attack , is a milder, less comprehensive panic attack with fewer than 4 panic related symptoms being experienced ....
s in between attacks, in situations where attacks have previously occurred.

Panic attacks are commonly linked to agoraphobia
Agoraphobia

Agoraphobia is an anxiety disorder, often precipitated by the fear of having a panic attack in a setting from which there is no easy means of escape....
 and the fear of not being able to escape a bad situation. Many who experience panic attacks feel trapped and unable to free themselves.

The effects of a panic attack vary from person to person. Some, notably first-time sufferers, may call for emergency services. Many who experience a panic attack, mostly for the first time, fear they are having a heart attack or a nervous breakdown
Nervous Breakdown

Nervous Breakdown was the first Extended play#The 7" EP in punk rock by the American hardcore punk band Black Flag . It was released in 1978 and was the inaugural release on SST Records....
.

Descriptions

Sufferers of panic attacks often report a fear or sense of dying, "going crazy", or experiencing a heart attack
Myocardial infarction

Myocardial infarction , commonly known as a heart attack, occurs when the Blood flow to part of the heart is interrupted. This is most commonly due to occlusion of a coronary artery following the rupture of a Vulnerable plaque, which is an unstable collection of lipids and white blood cells in the wall of an artery....
 or "flashing vision", feeling faint or nauseated
Vomiting

Vomiting is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Undesired vomiting may result from many causes, ranging from gastritis or poisoning to brain tumors, or elevated intracranial pressure....
, heavy breathing, or losing control of themselves. These feelings may provoke a strong urge to escape or flee the place where the attack began (a consequence of the sympathetic "fight or flight
Fight or Flight

Fight or Flight may refer to:* Fight-or-flight response, the biological response of animals to acute stress* Fight or Flight , an album by the British rock band Turin Brakes...
" response).

A panic attack is a response of the sympathetic nervous system
Sympathetic nervous system

The Sympathetic Nervous System is a branch of the autonomic nervous system along with the enteric nervous system and parasympathetic nervous system....
 (SNS). The most common symptoms may include trembling, dyspnea
Dyspnea

Dyspnea or dyspnoea , from Latin language dyspnoea, from Greek language dyspnoia from dyspnoos, shortness of breath) or shortness of breath is perceived to be difficulty of breathing or painful breathing that a patient is aware of....
 (shortness of breath), heart palpitations, chest pain
Chest pain

In medicine, chest pain is a symptom of a number of serious conditions and is generally considered a medical emergency. Even though it may be determined that the chest pain is non-cardiac in origin this is often a diagnosis of exclusion made after ruling out more serious causes of pain....
 (or chest tightness), hot flashes, cold flashes, burning sensations (particularly in the facial or neck area), sweating
Sweating

Perspiration is the production of a fluid, consisting primarily of water as well as various dissolved solids , that is excreted by the sweat glands in the skin of mammals....
, nausea
Nausea

Nausea is the sensation of unease and discomfort in the stomach with an urge to vomit....
, dizziness
Dizziness

Dizziness describes a number of subjective symptoms, which the patient may describe as feelings of lightheadedness, floating, wooziness, giddiness, confusion, disorientation or loss of balance....
 (or slight vertigo
Vertigo (medical)

Vertigo is a specific type of dizziness, a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is actually stationary with respect to the surroundings....
), light-headedness, hyperventilation
Hyperventilation

In medicine, hyperventilation is the state of breathing faster and/or deeper than necessary, bringing about lightheadedness and other undesirable symptoms often associated with panic attacks....
, paresthesia
Paresthesia

Paresthesia is a sensation of tingling, pricking, or numbness of a person's skin with no apparent long-term physical effect. It is more generally known as the feeling of "pins and needles" or of a human limb being "asleep" ....
s (tingling sensations), sensations of choking
Choking

Choking is the mechanical obstruction of the flow of air from the environment into the lungs. Choking prevents breathing, and can be partial or complete, with partial choking allowing some,...
 or smothering, and derealization
Derealization

Derealization is an alteration in the perception or experience of the external world so that it seems strange or unreal. Other symptoms include feeling as though one's environment is lacking in spontaneity, emotional colouring and depth....
. These physical symptoms are interpreted with alarm in people prone to panic attacks. This results in increased anxiety, and forms a positive feedback
Positive feedback

Positive feedback, sometimes referred to as "cumulative causation", is a feedback loop system in which the system responds to Perturbation of biological system in the same direction as the perturbation....
 loop.

Often the onset of shortness of breath and chest pain
Chest pain

In medicine, chest pain is a symptom of a number of serious conditions and is generally considered a medical emergency. Even though it may be determined that the chest pain is non-cardiac in origin this is often a diagnosis of exclusion made after ruling out more serious causes of pain....
 are the predominant symptoms, the sufferer incorrectly appraises this as a sign or symptom
Symptom

A symptom is a departure from normal function or feeling which is noticed by a patient, indicating the presence of disease or abnormality. A symptom is subjective, observed by the patient, and not measured....
 of a heart attack. This can result in the person experiencing a panic attack seeking treatment in an emergency room.

Panic attacks are distinguished from other forms of anxiety by their intensity and their sudden, episodic nature. They are often experienced in conjunction with anxiety disorders and other psychological conditions, although panic attacks are not always indicative of a mental disorder.

Triggers and causes

  • Long-term, predisposing causesHeredity
    Heredity

    Heredity is the passing of traits to offspring . This is the process by which an offspring cell or organism acquires or becomes predisposed to the characteristics of its parent cell or organism....
    . Panic disorder has been found to run in families, and this may mean that inheritance plays a strong role in determining who will get it. However, many people who have no family history of the disorder develop it. Various twin studies where one identical twin has an anxiety disorder have reported an incidence ranging from 31 to 88 percent of the other twin also having an anxiety disorder diagnosis. Environmental factors such as an overly cautious view of the world expressed by parents and cumulative stress over time have been found to be causes.


  • Biological causes — obsessive compulsive disorder, post traumatic stress disorder, hypoglycemia
    Hypoglycemia

    Hypoglycaemia or hypoglycemia is the medical term for a Pathology state produced by a lower than normal level of Blood glucose. The term hypoglycemia literally means "under-sweet blood" ....
    , hyperthyroidism
    Hyperthyroidism

    Hyperthyroidism is the term for overactive tissue within the thyroid gland,resulting in overproduction and thus an excess of circulating free thyroid hormones: thyroxine , triiodothyronine , or both....
    , Wilson's disease
    Wilson's disease

    Wilson's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in biological tissue; this manifests as neurology or psychiatry symptoms and liver disease....
    , mitral valve prolapse
    Mitral valve prolapse

    Mitral valve prolapse is a valvular heart disease characterized by the displacement of an abnormally thickened mitral valve leaflet into the atria of the heart during systole....
    , pheochromocytoma
    Pheochromocytoma

    A phaeochromocytoma is a neuroendocrine tumor of the Adrenal medulla of the adrenal glands , or extra-adrenal chromaffin tissue that failed to involute after birth and secretes excessive amounts of catecholamines, usually epinephrine and norepinephrine....
     and inner ear disturbances (labyrinthitis
    Labyrinthitis

    Labyrinthitis is a balance disorder. It is an inflammatory process affecting the Labyrinth s that house the vestibular system of the inner ear....
    ). Vitamin B deficiency from inadequate diet or caused by periodic depletion due to parasitic infection from tapeworm can be a trigger of anxiety attacks.


  • Phobias — People will often experience panic attacks as a direct result of exposure to a phobic object or situation.


  • Short-term triggering causes — Significant personal loss, including an emotional attachment to a romantic partner, life transitions, significant life change, stimulants such as caffeine
    Caffeine

    Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a psychoactive stimulant drug and a mild diuretic. Caffeine was discovered by a German chemist, Friedrich Ferdinand Runge, in 1819....
     or nicotine
    Nicotine

    Nicotine is an alkaloid found in the nightshade family of plants which constitutes approximately 0.6?3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves....
    , or the drugs marijuana or psilocybin
    Psilocybin

    Psilocybin is a psychedelic drug indole of the tryptamine family, found in psilocybin mushrooms. It is present in List of Psilocybin mushrooms of fungi, including those of the genus Psilocybe, such as Psilocybe cubensis and liberty cap , but also reportedly isolated from a dozen or so other genera....
    , can act as triggers.


  • Maintaining causes — Avoidance of panic provoking situations or environments, anxious/negative self-talk ("what-if" thinking), mistaken beliefs ("these symptoms are harmful and/or dangerous"), withheld feeling
    Feeling

    Feeling is the nominalization of to feel. The word was first used in the English language to describe the physical sensation of touch either through experience or perception....
    s, lack of assertiveness.


  • Lack of assertiveness — A growing body of evidence
    Evidence

    Evidence in its broadest sense includes everything that is used to determine or demonstrate the truth of an assertion. Giving or procuring evidence is the process of using those things that are either a) presumed to be true, or b) were themselves proven via evidence, to demonstrate an assertion's truth....
     supports the idea that those that suffer from panic attacks engage in a passive
    Passive

    Passive is the opposite of active. It has several specific meanings:* Passive voice of a verb* Passivation is the formation of a non-reactive surface film that inhibits further corrosion of a metal...
     style of communication or interactions with others. This communication style, while polite and respectful, is also characteristically un-assertive. This un-assertive way of communicating seems to contribute to panic attacks while being consistently present in those that are afflicted with panic attacks.


  • Medications — Sometimes panic attacks may be a listed side effect of medications such as Ritalin (methylphenidate
    Methylphenidate

    Methylphenidate is the most commonly medical prescription psychostimulant and is indicated in the treatment of attention-deficit hyperactivity disorder and narcolepsy, although off-label uses include treating lethargy, depression, neural insult and obesity....
    ) or even fluoroquinolone type antibiotics. These may be a temporary side effect, only occurring when a patient first starts a medication, or could continue occurring even after the patient is accustomed to the drug, which likely would warrant a medication change in either dosage, or type of drug. Nearly the entire SSRI class of antidepressants can cause increased anxiety in the beginning of use. It is not uncommon for inexperienced users to have panic attacks while weaning on or off the medication, especially ones prone to anxiety.


  • Alcohol, medication or drug withdrawal — Various substances both prescribed and unprescribed can cause panic attacks to develop as part of their withdrawal syndrome or rebound effect
    Rebound effect

    Rebound effect is the tendency of a medication to, when discontinued to cause a return of the symptoms being treated more severe than before. Medications with a known rebound effect can be withdrawn gradually or in conjunction with another medication which does not exhibit a rebound effect....
    . Alcohol withdrawal and benzodiazepine withdrawal are the most well known to cause these effects as a rebound withdrawal symptom of their tranquillising properties.


  • Hyperventilation syndrome — Breathing from the chest may cause overbreathing, exhaling excess carbon dioxide
    Carbon dioxide

    Carbon dioxide is a chemical compound composed of two oxygen atoms covalent bond to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state....
     in relation to the amount of oxygen
    Oxygen

    Oxygen no O2 produced; 2) O2 produced, but absorbed in oceans & seabed rock; 3) O2 starts to gas out of the oceans, but is absorbed by land surfaces and formation of ozone layer; 4-5) O2 sinks filled and the gas accumulates]]...
     in one's bloodstream. Hyperventilation syndrome
    Hyperventilation syndrome

    Hyperventilation syndrome is a respiratory disorder, psychologically or physiologically based, involving breathing too deeply or too rapidly . HVS may present with chest pain and a tingling sensation in the fingertips and around the mouth and may accompany a panic attack....
     can cause respiratory alkalosis
    Respiratory alkalosis

    Respiratory alkalosis results from increased alveoli respiration leading to decreased plasma carbon dioxide concentration. This leads to decreased hydrogen ion and freely ionized blood calcium concentrations....
     and hypocapnia
    Hypocapnia

    Hypocapnia or hypocapnea also known as hypocarbia, sometimes incorrectly called acapnia, is a state of reduced carbon dioxide in the blood....
    . This syndrome often involves prominent mouth breathing as well. This causes a cluster of symptoms including rapid heart beat, dizziness
    Dizziness

    Dizziness describes a number of subjective symptoms, which the patient may describe as feelings of lightheadedness, floating, wooziness, giddiness, confusion, disorientation or loss of balance....
    , and lightheadedness
    Lightheadedness

    Light-headedness is a common and often unpleasant sensation of dizziness and/or feeling that one may be about to fainting , which may be transient, recurrent, or occasionally chronic ....
     which can trigger panic attacks.


  • Situationally bound panic attacks — Associating certain situations with panic attacks, due to experiencing one in that particular situation, can create a cognitive or behaviorally predisposition to having panic attacks in certain situations (situationally bound panic attacks). It is a form of classical conditioning. See PTSD


  • Pharmacological triggers — Certain chemical substances, mainly stimulants but also certain depressants, can either contribute pharmacologically to a constellation of provocations, and thus trigger a panic attack or even a panic disorder, or directly induce one. This includes caffeine, amphetamine, alcohol and many more. Some sufferers of panic attacks also report phobias of specific drugs or chemicals, that thus have a merely psychosomatic effect, thereby functioning as drug-triggers by non-pharmacological means.


  • Chronic and/or serious illness — Cardiac conditions that can cause Sudden Death
    Sudden death

    In a sport or game, sudden death is a form of competition where play ends as soon as one competitor is ahead of the others, with that competitor becoming the winner....
     such as Long QT syndrome
    Long QT syndrome

    The long QT syndrome is a rare congenital heart condition with delayed repolarization following depolarization of the heart, associated with fainting due to left ventricle cardiac arrhythmia, possibly of type torsade de pointes, which can deteriorate into ventricular fibrillation and ultimately Sudden cardiac death....
    ; CPVT or Wolff-Parkinson-White syndrome
    Wolff-Parkinson-White syndrome

    Wolff-Parkinson-White syndrome is a syndrome of pre-excitation of the Ventricle of the heart due to an accessory pathway known as the bundle of Kent....
     can also result in panic attacks. This is particularly difficult to manage as the anxiety
    Anxiety

    Anxiety is a psychological and physiological state characterized by cognitive, somatic, emotional, and behavioral components. These components combine to create an unpleasant feeling that is typically associated with uneasiness, fear, or worry....
     relates to events that may occur such as cardiac arrest, or if an Implantable cardioverter-defibrillator
    Implantable cardioverter-defibrillator

    An implantable cardioverter-defibrillator is a small battery -powered electrical impulse generator which is implanted in patients who are at risk of sudden cardiac death due to ventricular fibrillation....
     is in situ, the possibility of having a shock delivered. It can be difficult for someone with a cardiac condition to distinguish between symptoms of cardiac dysfunction and symptoms of anxiety. In CPVT, anxiety itself can and does trigger arrythmia.Current management of panic attacks secondary to cardiac conditions appears to rely heavily on Benzodiazepines; Selective serotonin reuptake inhibitors and/or Cognitive Behavioural Therapy. Although often this group of people experience multiple and unavoidable hospitalisations as without an electrocardiogram
    Electrocardiogram

    An electrocardiogram is a recording of the electricity activity of the heart over time produced by an electrocardiograph, usually in a Non-invasive recording via skin electrodes....
     it can be difficult to differentiate between symptoms of panic attack and cardiac symptoms in those with these types of diagnosis.


Physiological considerations

While the various symptoms of a panic attack may feel that the body is failing, it is in fact protecting itself from harm. The various symptoms of a panic attack can be understood as follows. First, there is frequently (but not always) the sudden onset of fear with little provoking stimulus. This leads to a release of adrenaline (epinephrine) which brings about the so-called fight-or-flight response
Fight-or-flight response

'The 'fight-or-flight response', also called the fright, fight or flight response', 'hyperarousal' or the 'acute stress response', was first described by Walter Cannon in 1915....
 wherein the person's body prepares for strenuous physical activity. This leads to an increased heart rate (tachycardia
Tachycardia

The word tachycardia comes from the Greek words tachys and kardia .Tachycardia typically refers to a heartrate that exceeds the range of the normal resting heartrate, based upon age:...
), rapid breathing (hyperventilation
Hyperventilation

In medicine, hyperventilation is the state of breathing faster and/or deeper than necessary, bringing about lightheadedness and other undesirable symptoms often associated with panic attacks....
) which may be perceived as shortness of breath (dyspnea
Dyspnea

Dyspnea or dyspnoea , from Latin language dyspnoea, from Greek language dyspnoia from dyspnoos, shortness of breath) or shortness of breath is perceived to be difficulty of breathing or painful breathing that a patient is aware of....
), and sweating (which increases grip and aids heat loss). Because strenuous activity rarely ensues, the hyperventilation leads to a drop in carbon dioxide
Carbon dioxide

Carbon dioxide is a chemical compound composed of two oxygen atoms covalent bond to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state....
 levels in the lung
Lung

The lung is the essential respiration organ in air-breathing animals, including most tetrapods, a few fish and a few snails. In mammals and the more complex life forms, the two lungs are located in the chest on either side of the heart....
s and then in the blood
Blood

Blood is a specialized bodily fluid that delivers necessary substances to the body's Cell s ? such as nutrients and oxygen ? and transports waste products away from those same cells....
. This leads to shifts in blood pH
PH

pH is a measure of the Acid or Base of a solution. It is defined as the cologarithm of the Activity of dissolved hydrogen ions . Hydrogen ion activity coefficients cannot be measured experimentally, so they are based on theoretical calculations....
 (respiratory alkalosis
Respiratory alkalosis

Respiratory alkalosis results from increased alveoli respiration leading to decreased plasma carbon dioxide concentration. This leads to decreased hydrogen ion and freely ionized blood calcium concentrations....
 or hypocapnia
Hypocapnia

Hypocapnia or hypocapnea also known as hypocarbia, sometimes incorrectly called acapnia, is a state of reduced carbon dioxide in the blood....
), which in turn can lead to many other symptoms, such as tingling or numbness
Paresthesia

Paresthesia is a sensation of tingling, pricking, or numbness of a person's skin with no apparent long-term physical effect. It is more generally known as the feeling of "pins and needles" or of a human limb being "asleep" ....
, dizziness
Dizziness

Dizziness describes a number of subjective symptoms, which the patient may describe as feelings of lightheadedness, floating, wooziness, giddiness, confusion, disorientation or loss of balance....
, burning and lightheadedness
Lightheadedness

Light-headedness is a common and often unpleasant sensation of dizziness and/or feeling that one may be about to fainting , which may be transient, recurrent, or occasionally chronic ....
. Moreover, the release of adrenaline during a panic attack causes vasoconstriction
Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, particularly the large arteries, arterioles and veins....
 resulting in slightly less blood flow
Blood flow

Blood flow is the flow of blood in the cardiovascular system.It can be calculated by dividing the vascular resistance into the pressure gradient....
 to the head which causes dizziness
Dizziness

Dizziness describes a number of subjective symptoms, which the patient may describe as feelings of lightheadedness, floating, wooziness, giddiness, confusion, disorientation or loss of balance....
 and lightheadedness
Lightheadedness

Light-headedness is a common and often unpleasant sensation of dizziness and/or feeling that one may be about to fainting , which may be transient, recurrent, or occasionally chronic ....
. A panic attack can cause blood sugar
Blood sugar

Blood sugar concentration, or glucose level, refers to the amount of glucose present in a mammal's blood. Normally, the blood glucose level is maintained at a Reference_ranges_for_blood_tests#Electrolytes_and_Metabolites between about 4 and 6 mM ....
 to be drawn away from the brain
Brain

The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
 and towards the major muscles. It is also possible for the person experiencing such an attack to feel as though they are unable to catch their breath, and they begin to take deeper breaths, which also acts to decrease carbon dioxide levels in the blood.

Symptoms

  • Heart palpitations
  • Diaphoresis
    Diaphoresis

    Diaphoresis is excessive Perspiration commonly associated with Shock and other medical emergency conditions.Diaphoretic is the state of perspiring profusely, or something that has the power to cause increased perspiration....
     or perspiration
  • Trembling or tremors
  • Dyspnea
    Dyspnea

    Dyspnea or dyspnoea , from Latin language dyspnoea, from Greek language dyspnoia from dyspnoos, shortness of breath) or shortness of breath is perceived to be difficulty of breathing or painful breathing that a patient is aware of....
     (trouble breathing)
  • Hyperventilation
    Hyperventilation

    In medicine, hyperventilation is the state of breathing faster and/or deeper than necessary, bringing about lightheadedness and other undesirable symptoms often associated with panic attacks....
  • Chills
  • Hot flashes
  • Nausea
    Nausea

    Nausea is the sensation of unease and discomfort in the stomach with an urge to vomit....
  • Abdominal pain
    Abdominal pain

    Abdominal pain can be one of the symptoms associated with transient disorders or serious disease. Making a definitive diagnosis of the cause of abdominal pain can be difficult, because many diseases can result in this symptom....
  • Chest pain
    Chest pain

    In medicine, chest pain is a symptom of a number of serious conditions and is generally considered a medical emergency. Even though it may be determined that the chest pain is non-cardiac in origin this is often a diagnosis of exclusion made after ruling out more serious causes of pain....
  • Headache
    Headache

    In medicine a headache or wiktionary:cephalalgia is a symptom of a number of different conditions of the head and sometimes neck. Some of the causes are benign while others are medical emergencies....
  • Dizziness
    Dizziness

    Dizziness describes a number of subjective symptoms, which the patient may describe as feelings of lightheadedness, floating, wooziness, giddiness, confusion, disorientation or loss of balance....
  • Lightheadedness
    Lightheadedness

    Light-headedness is a common and often unpleasant sensation of dizziness and/or feeling that one may be about to fainting , which may be transient, recurrent, or occasionally chronic ....
  • Faintness
  • Tightness
    Tightness

    In mathematics,* Tightness of measures is a concept in measure theory in mathematics* Tightness is also a cardinal function used in general topology....
     in throat
  • Tunnel vision
    Tunnel vision

    In medical terms, tunnel vision is the loss of peripheral vision with retention of central vision, resulting in a constricted circular tunnel-like visual field....
  • Trouble swallowing
    Swallowing

    "Gulp" redirects here. For other uses, see Gulp .Swallowing, known scientifically as deglutition, is the process in the human or animal body that makes something pass from the mouth, to the pharynx, into the esophagus, with the shutting of the epiglottis....
  • A sense of impending death
    Death

    Death is the permanent termination of the biological functions that define a life organism. It refers to both a particular event and to the condition that results thereby....
  • Feeling like one is experiencing a myocardial infarction
    Myocardial infarction

    Myocardial infarction , commonly known as a heart attack, occurs when the Blood flow to part of the heart is interrupted. This is most commonly due to occlusion of a coronary artery following the rupture of a Vulnerable plaque, which is an unstable collection of lipids and white blood cells in the wall of an artery....
     (heart attack)

Agoraphobia

Agoraphobia is an anxiety disorder
Anxiety disorder

Anxiety disorder is a blanket term covering several different forms of abnormal and pathological fears and anxieties.Although in casual discourse the words anxiety, fear, and phobia are often used interchangeably, in clinical usage, they have distinct meanings....
 which primarily consists of the fear of experiencing a difficult or embarrassing situation from which the sufferer cannot escape. As a result, severe sufferers of agoraphobia may become confined to their homes, experiencing difficulty traveling from this "safe place". The word "agoraphobia" is an English adoption of the Greek
Greek language

Greek is an Indo-European languages native to the southern Balkan peninsula, the language of the Greek people. It forms an independent branch within Indo-European....
 words agora
Agora

The Agora was an open "place of assembly" in ancient Ancient Greece city-states. Early in Greek history , free-born male land-owners who were citizens would gather in the agora for military duty or to hear statements of the ruling king or council....
 (a????) and phobos
Phobos

Phobos, Greek language for "fear", is the root word of phobia. It may refer to:*Phobos , one of the sons of Ares and Aphrodite in Greek mythology...
 (f?ß??), literally translated as "a fear of the marketplace" usually applies to any or all public places; however the essence of agoraphobia is a fear of panic attacks especially if they occur in public as the victim may feel like he or she has no escape and be very embarrassed of having one publicly in the first place. This translation is the reason for the common misconception that agoraphobia is a fear of open spaces, and is not clinically accurate.

People who have had a panic attack in certain situations may develop irrational fears, called phobias, of these situations and begin to avoid them. Eventually, the pattern of avoidance and level of anxiety about another attack may reach the point where individuals with panic disorder are unable to drive or even step out of the house. At this stage, the person is said to have panic disorder with agoraphobia
Agoraphobia

Agoraphobia is an anxiety disorder, often precipitated by the fear of having a panic attack in a setting from which there is no easy means of escape....
. This can be one of the most harmful side-effects of panic disorder as it can prevent sufferers from seeking treatment in the first place. It should be noted that upwards of 90% of agoraphobics achieve a full recovery. Agoraphobia is actually not a fear of certain places but a fear of having panic attacks in certain places.

It is important to note that agoraphobia is by no means a hopeless situation. Sufferers often do not realize that they have experienced these same situations before and nothing terrible occurred. Successful treatment is possible with the right combination of therapy and medication.

Panic disorder

People who have repeated, persistent attacks or feel severe anxiety about having another attack are said to have panic disorder. Panic disorder is strikingly different from other types of anxiety disorder
Anxiety disorder

Anxiety disorder is a blanket term covering several different forms of abnormal and pathological fears and anxieties.Although in casual discourse the words anxiety, fear, and phobia are often used interchangeably, in clinical usage, they have distinct meanings....
s in that panic
Panic

Panic is a sudden fear which dominates or replaces thinking and often affects groups of people or animals. Panics typically occur in disaster situations, or violent situations which may endanger the overall health of the affected group....
 attacks are often sudden and unprovoked.

Treatment

People with panic attack
Panic attack

Panic attacks are very sudden, discrete periods of intense anxiety, mounting physiological arousal, fear, stomach problems and discomfort that are associated with a variety of somatic and cognitive symptoms....
s often can be successfully treated with therapy, particularly cognitive behavioral therapy and/or anti-anxiety medication or antidepressants.

Paper bag rebreathing


Many panic attack sufferers as well as doctors recommend breathing into a paper bag as an effective short-term treatment of an acute panic attack. However, this treatment has been criticised by others as ineffective and possibly harzardous to the patient, even potentially worsening the panic attack. They say it can fatally lower oxygen
Oxygen

Oxygen no O2 produced; 2) O2 produced, but absorbed in oceans & seabed rock; 3) O2 starts to gas out of the oceans, but is absorbed by land surfaces and formation of ozone layer; 4-5) O2 sinks filled and the gas accumulates]]...
 levels in the blood stream, and increase carbon dioxide
Carbon dioxide

Carbon dioxide is a chemical compound composed of two oxygen atoms covalent bond to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state....
 levels, which in turn has been found to be a major cause of panic attacks.

It is therefore important to discover whether hyperventilation is truly involved in each case. If it is, then rebalancing the oxygen/CO2 levels in the blood and/or re-establishing an even, measured breathing pattern is an appropriate treatment which may be also achieved by extending the outbreath either by counting or even humming.

Medication

The benzodiazepine
Benzodiazepine

The benzodiazepines are a class of psychoactive drugs with varying hypnotic, sedative, anxiolytic , anticonvulsant, muscle relaxant and anterograde amnesia properties, which are mediated by slowing down the central nervous system....
 class of drugs includes diazepam
Diazepam

Diazepam , first marketed as Valium by Hoffmann-La Roche, is a benzodiazepine derivative drug. It possesses anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant and amnestic properties....
, lorazepam
Lorazepam

Lorazepam, initially marketed under the brand names Ativan and Temesta, is a benzodiazepine drug with short to medium duration of action....
, alprazolam
Alprazolam

Alprazolam, also known under the #Availability Xanax, Xanor and Niravam, is a short-acting drug of the benzodiazepine class used to treat moderate to severe anxiety disorders, panic attacks, and as an adjunctive treatment for anxiety associated with moderate clinical depression....
, and clonazepam
Clonazepam

Clonazepam is a benzodiazepine derivative with highly potent anticonvulsant, muscle relaxant and anxiolytic properties. It is marketed by Hoffmann-La Roche under the trade-names Klonopin in the United States and Rivotril in various other English speaking countries....
. These drugs are fast acting in stopping panic but long-term use often leads to tolerance and physical dependence
Physical dependence

Physical dependence refers to a state resulting from chronic use of a drug that has produced Tolerance and where negative physical symptoms of withdrawal result from abrupt discontinuation or dosage reduction....
. Benzodiazepines are best used for a few days to avoid the development of tolerance or dependence. Some doctors may prefer to prescribe an antidepressant, particularly an SSRI (such as paroxetine
Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor antidepressant. It was released in 1992 by the pharmaceutical company GlaxoSmithKline. It is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder and social phobia disorders in adult Patient#Outpatient vs inpatient....
, sertraline
Sertraline

Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor class. It was introduced to the market by Pfizer in 1991....
, fluvoxamine
Fluvoxamine

Fluvoxamine is an antidepressant which functions as a selective serotonin reuptake inhibitor. It is most often used to treat obsessive-compulsive disorder....
, escitalopram
Escitalopram

Escitalopram is the pure enantiomer of racemic citalopram and is a selective serotonin reuptake inhibitor . Escitalopram is used in the treatment of Major depressive disorder and anxiety....
 or fluoxetine
Fluoxetine

Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor class. Fluoxetine is approved for the treatment of major depressive disorder , obsessive-compulsive disorder , bulimia nervosa, anorexia nervosa, panic disorder and premenstrual dysphoric disorder....
), which after an initial titration
Titration

Titration is a common laboratory method of quantitative Analytical chemistry that is used to determine the unknown concentration of a known reactant....
 period may be effective at reducing anxiety and panic attacks. SNRIs such as Venlafaxine
Venlafaxine

Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor class first introduced by Wyeth in 1993. It is prescribed for the treatment of major depressive disorder and anxiety disorders, among other uses....
 can also be prescribed, but may be addictive and may increase suicide ideation, but have less abuse potential than benzodiazepines

Other treatments


All persons experiencing persistent and frequent panic attacks should consult their physicians. However, many experienced sufferers treat panic attacks with some the following methods and techniques:

  • Diaphragmatic breathing or abdominal breathing — Breathing slowly through the nose using the diaphragm and abdomen. Do not breathe through the mouth. Focus on exhaling very slowly. This will correct or prevent an imbalance of oxygen to carbon dioxide in the blood stream.


  • Taking anti-anxiety medication — to be used under the guidance and direction of a physician
    Physician

    A physician, medical practitioner, doctor of medicine, or medical doctor practices medicine, and is concerned with maintaining or restoring human health through the study, diagnosis, and treatment of disease and injury....
    .


  • Staying in the present — rather than having "what if" thoughts that are future oriented asking yourself, "what is happening now" and "how do I wish to respond to it". (Carbonell, 2004)


  • Acceptance and acknowledgement- accepting and acknowledging the panic attack. (Carbonell, 2004).


  • Floating with the symptoms — allowing time to pass and floating with the symptoms rather than trying to make them better or fighting them. (Carbonell, 2004)


  • Coping statements — repeated as part of an internal monologue


    • "No one has ever died from an anxiety attack."
    • "I will let my body do its thing. This will pass."
    • "I can be anxious and still deal with this situation."
    • "This does not feel great, but I can deal with it".
    • "I am frightened of being frightened, therefore if I stop worrying about being frightened, then I have nothing to be scared of."


  • Talking to a supportive person — someone who has experienced true panic attacks personally; someone who is highly trained in treating panic attacks; loved ones who can offer support and comfort.


  • One particularly helpful and effective form of therapy is cognitive behavioral therapy (CBT). This is the most generally accepted method of treatment.


  • Lying down — to prevent fainting during an attack.


Increased risk of heart attack and stroke

A recent study suggests that menopausal women with panic disorder and many occurrences of panic attacks have a threefold higher risk of suffering heart attack or stroke
Stroke

A stroke is the rapidly developing loss of brain function due to a disturbance in the blood supply to the brain. According to the National Stroke Association, a "stroke" occurs when a blood clot blocks and artery or a blood vessel breaks, interrupting blood flow to an area of the brain....
 over the next five years. The researchers believe that panic attacks or more accurately their associated symptoms (chest pain
Chest pain

In medicine, chest pain is a symptom of a number of serious conditions and is generally considered a medical emergency. Even though it may be determined that the chest pain is non-cardiac in origin this is often a diagnosis of exclusion made after ruling out more serious causes of pain....
, dyspnea
Dyspnea

Dyspnea or dyspnoea , from Latin language dyspnoea, from Greek language dyspnoia from dyspnoos, shortness of breath) or shortness of breath is perceived to be difficulty of breathing or painful breathing that a patient is aware of....
) can be manifestations of undiagnosed cardiovascular disease, or result in heart damage due to cardiovascular stress in patients with panic disorder and many panic attacks over periods of years. The study did not find that isolated cases of panic attacks in patients without panic disorder
Panic disorder

Panic Disorder is an anxiety disorder characterized by recurring severe panic attacks. It may also include significant behavioral change lasting at least a month and of ongoing worry about the implications or concern about having other attacks....
 or agoraphobia
Agoraphobia

Agoraphobia is an anxiety disorder, often precipitated by the fear of having a panic attack in a setting from which there is no easy means of escape....
 lead to immediate heart damage, nor did it prove that the correlation between panic disorder and strokes was causal, or that it couldn't be attributed to the cardiovascular effects of medication that many panic disorder patients receive, such as SSRIs and benzodiazepines. For example one study albeit in the elderly found that the consumption of benzodiazepines combined with analgesics in elderly men is correlated with an increased risk of dying of ischaemic heart disease
Ischaemic heart disease

Ischaemic or ischemic heart disease , or myocardial ischaemia, is a disease characterized by reduced blood supply to the myocardium, usually due to Coronary heart disease ....
 in a small study. The study doesn't say if this is to be blamed on the benzodiazepine drug in this case nitrazepam
Nitrazepam

Nitrazepam is a type of benzodiazepine drug and is marketed in English speaking countries under the following brand names - Alodorm, Arem, Insoma, Mogadon, Nitrados, Nitrazadon, Ormodon, Paxadorm, Remnos and Somnite....
, the analgetics or their combination.

Limited symptom attack


Many people being treated for panic attacks begin to experience limited symptom attack
Limited symptom attack

A Limited Symptom Attack , also referred to as a Limited Symptom Panic Attack , is a milder, less comprehensive panic attack with fewer than 4 panic related symptoms being experienced ....
s. These panic attacks are less comprehensive with fewer than 4 bodily symptoms being experienced.

External links

  • Information for families, clinicians and researchers
  • on the United States Surgeon General Website
  • by About.com