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Maud Menten

 

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Maud Menten



 
 
Maud Leonora Menten (March 20, 1879 – July 26, 1960) was a Canadian
Canada

Canada is a country occupying most of northern North America, extending from the Atlantic Ocean in the east to the Pacific Ocean in the west and northward into the Arctic Ocean....
 medical scientist who made significant contributions to enzyme kinetics
Enzyme kinetics

Enzyme kinetics is the study of the chemical reactions that are catalyst by enzymes, with a focus on their reaction rates. The study of an enzyme's chemical kinetics reveals the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled, and how a drug or a poison might enzyme inhibitor the enzyme....
 and histochemistry. Her name is associated with the famous Michaelis-Menten equation
Michaelis-Menten kinetics

File:Michaelis-Menten.pngMichaelis?Menten kinetics approximately describes the enzyme kinetics of many enzymes. It is named after Leonor Michaelis and Maud Menten....
.

Maud Menten was born in Port Lambton, Ontario
Port Lambton, Ontario

Port Lambton is a village situated on the St. Clair River, in southwestern Ontario, Canada within the municipality of St. Clair, Ontario. According to the latest census, 1084 people live within this Lambton County, Ontario community....
 and studied medicine
Medicine

Medicine is the art and science of healing. It encompasses a range of health care practices evolved to maintain and restore health by the prevention and treatment of illness....
 at the University of Toronto
University of Toronto

The University of Toronto is a public university research university in Toronto, Ontario, Canada, situated a mile north of the city's Financial District, Toronto on grounds that surround Queen's Park ....
 (B.A. 1904, M.B. 1907, M.D. 1911). She was among the first women in Canada to earn a medical doctorate. She completed her thesis work at University of Chicago
University of Chicago

The University of Chicago is a private university located principally in the Hyde Park, Chicago neighborhood of Chicago. Although an older university by the same name existed prior to its founding, the modern University of Chicago credits its founding to the oil magnate John D....
.






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Maud Leonora Menten (March 20, 1879 – July 26, 1960) was a Canadian
Canada

Canada is a country occupying most of northern North America, extending from the Atlantic Ocean in the east to the Pacific Ocean in the west and northward into the Arctic Ocean....
 medical scientist who made significant contributions to enzyme kinetics
Enzyme kinetics

Enzyme kinetics is the study of the chemical reactions that are catalyst by enzymes, with a focus on their reaction rates. The study of an enzyme's chemical kinetics reveals the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled, and how a drug or a poison might enzyme inhibitor the enzyme....
 and histochemistry. Her name is associated with the famous Michaelis-Menten equation
Michaelis-Menten kinetics

File:Michaelis-Menten.pngMichaelis?Menten kinetics approximately describes the enzyme kinetics of many enzymes. It is named after Leonor Michaelis and Maud Menten....
.

Maud Menten was born in Port Lambton, Ontario
Port Lambton, Ontario

Port Lambton is a village situated on the St. Clair River, in southwestern Ontario, Canada within the municipality of St. Clair, Ontario. According to the latest census, 1084 people live within this Lambton County, Ontario community....
 and studied medicine
Medicine

Medicine is the art and science of healing. It encompasses a range of health care practices evolved to maintain and restore health by the prevention and treatment of illness....
 at the University of Toronto
University of Toronto

The University of Toronto is a public university research university in Toronto, Ontario, Canada, situated a mile north of the city's Financial District, Toronto on grounds that surround Queen's Park ....
 (B.A. 1904, M.B. 1907, M.D. 1911). She was among the first women in Canada to earn a medical doctorate. She completed her thesis work at University of Chicago
University of Chicago

The University of Chicago is a private university located principally in the Hyde Park, Chicago neighborhood of Chicago. Although an older university by the same name existed prior to its founding, the modern University of Chicago credits its founding to the oil magnate John D....
. At that time women were not allowed to do research in Canada, therefore she decided to do research in other countries such as the United States
United States

The United States of America is a Federal government constitutional republic comprising U.S. state and a federal district. The country is situated mostly in central North America, where its Contiguous United States and Washington, D.C., the Capital districts and territories, lie between the Pacific Ocean and Atlantic Oceans, Borders of the U...
 and Germany
Germany

Germany , officially the Federal Republic of Germany , is a country in Central Europe. It is bordered to the north by the North Sea, Denmark, and the Baltic Sea; to the east by Poland and the Czech Republic; to the south by Austria and Switzerland; and to the west by France, Luxembourg, Belgium, and the Netherlands....
.

In 1912 she moved to Berlin
Berlin

Berlin is the Capital of Germany city and one of sixteen States of Germany of Germany. With a population of 3.4 million within its city limits, Berlin is the country's largest city....
 where she worked with Leonor Michaelis
Leonor Michaelis

Leonor Michaelis was a Germany biochemist and physician famous for his work with Maud Menten in enzyme kinetics and Michaelis-Menten kinetics....
, obtaining a Ph.D. in 1916. Menten worked as a pathologist at the University of Pittsburgh
University of Pittsburgh

The University of Pittsburgh, commonly referred to as Pitt, is a Commonwealth System of Higher Education research university located in Pittsburgh, Pennsylvania, Pennsylvania, United States....
 (1923–1950) and as a research fellow at the British Columbia Medical Research Institute (1951–1953).

Her most famous work was on enzyme kinetics together with Michaelis, based on earlier findings of Victor Henri. This resulted in the Michaelis-Menten
Michaelis-Menten kinetics

File:Michaelis-Menten.pngMichaelis?Menten kinetics approximately describes the enzyme kinetics of many enzymes. It is named after Leonor Michaelis and Maud Menten....
 equations. Menten also invented the azo-dye coupling reaction for alkaline phosphatase
Alkaline phosphatase

Alkaline phosphatase is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids....
, which is still used in histochemistry. She characterised bacterial toxins from B. paratyphosus, S. scarlatinae and Salmonella
Salmonella

Salmonella is a genus of rod-shaped Gram-negative enterobacteriaceae that causes typhoid fever, paratyphoid fever, and the foodborne illness salmonellosis....
 ssp.
) and conducted the first electrophoretic
Electrophoresis

Electrophoresis is the best-known electrokinetic phenomena. It was discovered by Reuss in 1807. He observed that clay particles dispersed in water migrate under influence of an applied electric field....
 separation of proteins in 1944. She worked on the properties of hemoglobin
Hemoglobin

Hemoglobin is the iron-containing oxygen-transport metalloprotein in the red blood cells of vertebrates, and the tissues of some invertebrates....
, regulation of blood sugar
Blood sugar

Blood sugar concentration, or glucose level, refers to the amount of glucose present in a mammal's blood. Normally, the blood glucose level is maintained at a Reference_ranges_for_blood_tests#Electrolytes_and_Metabolites between about 4 and 6 mM ....
 level, and kidney function. Despite suffering from arthritis she was also an accomplished musician and painter; there were several exhibitions of her paintings.

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