Hemostasis (Greek a?µ?stas?? a?µa blood+st?s?? stagnation) is a complex process which causes the bleeding process to stop. Most time this includes the changing of blood from a fluid to a solid state. Intact blood vessels are central to moderating blood's tendency to clot. The endothelial cells of intact vessels prevent thrombus formation by secreting tissue plasminogen activator (t-PA) and by inactivating thrombin and adenosine diphosphate (ADP).
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Hemostasis (Greek a?µ?stas?? a?µa blood+st?s?? stagnation) is a complex process which causes the bleeding process to stop. Most time this includes the changing of blood from a fluid to a solid state. Intact blood vessels are central to moderating blood's tendency to clot. The endothelial cells of intact vessels prevent thrombus formation by secreting tissue plasminogen activator (t-PA) and by inactivating thrombin and adenosine diphosphate (ADP). Injury to vessels overwhelms these protective mechanisms and hemostasis ensues. Hemostasis proceeds in two phases: primary and secondary hemostasis.
