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Eosinophilic

 

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Eosinophilic



 
 
Eosinophilic means loves eosin, and refers to the stain
Stain

A stain is a discoloration that can be clearly distinguished from the surface, material, or medium it is found upon. Stains are caused by the chemical or physical interaction of two dissimilar materials....
ing of certain tissues
Biological tissue

Tissue is a cellular organizational level intermediate between cells and a complete organism. Hence, a tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function....
, cells
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
, or organelle
Organelle

In cell biology, an organelle is a specialized subunit within a cell that has a specific function, and is usually separately enclosed within its own lipid membrane....
s after they have been washed with eosin
Eosin

Eosin is a fluorescent red dye resulting from the action of bromine on fluorescein. It can be used to stain cytoplasm, collagen and Muscle#Muscular Composition for examination under the microscope....
, a dye
Dye

A dye can generally be described as a colored substance that has an Chemical affinity to the Wiktionary:substrate to which it is being applied....
.

Eosin is an acidic dye; thus, the structure being stained is basic
Base (chemistry)

In chemistry, a base is most commonly thought of as an aqueous substance that can accept protons. A base is also often referred to as an alkali if OH- ions are involved....
.

Eosinophilic describes the appearance of cells and structures seen in histological section
Histological section

Histology section refers to thin slices of Biological tissue applied to a microscopic slide, usually around 5 to 10 micrometres thick, which are viewed under a microscope....
s that take up the staining dye eosin
Eosin

Eosin is a fluorescent red dye resulting from the action of bromine on fluorescein. It can be used to stain cytoplasm, collagen and Muscle#Muscular Composition for examination under the microscope....
. This is a bright-pink dye that stains the cytoplasm of cells, as well as extracellular proteins such as collagen
Collagen

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content....
.

Such eosinophilic structures are, in general, composed of protein
Protein

Proteins are organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid Residue ....
.

The stain eosin is usually combined with a stain called hematoxylin to produce a hematoxylin and eosin-stained section
Section

selfref|For the sectioning of Wikipedia articles, see...
 (also called an H&E, HE or H+E section).






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Eosinophilic means loves eosin, and refers to the stain
Stain

A stain is a discoloration that can be clearly distinguished from the surface, material, or medium it is found upon. Stains are caused by the chemical or physical interaction of two dissimilar materials....
ing of certain tissues
Biological tissue

Tissue is a cellular organizational level intermediate between cells and a complete organism. Hence, a tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function....
, cells
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
, or organelle
Organelle

In cell biology, an organelle is a specialized subunit within a cell that has a specific function, and is usually separately enclosed within its own lipid membrane....
s after they have been washed with eosin
Eosin

Eosin is a fluorescent red dye resulting from the action of bromine on fluorescein. It can be used to stain cytoplasm, collagen and Muscle#Muscular Composition for examination under the microscope....
, a dye
Dye

A dye can generally be described as a colored substance that has an Chemical affinity to the Wiktionary:substrate to which it is being applied....
.

Eosin is an acidic dye; thus, the structure being stained is basic
Base (chemistry)

In chemistry, a base is most commonly thought of as an aqueous substance that can accept protons. A base is also often referred to as an alkali if OH- ions are involved....
.

Eosinophilic describes the appearance of cells and structures seen in histological section
Histological section

Histology section refers to thin slices of Biological tissue applied to a microscopic slide, usually around 5 to 10 micrometres thick, which are viewed under a microscope....
s that take up the staining dye eosin
Eosin

Eosin is a fluorescent red dye resulting from the action of bromine on fluorescein. It can be used to stain cytoplasm, collagen and Muscle#Muscular Composition for examination under the microscope....
. This is a bright-pink dye that stains the cytoplasm of cells, as well as extracellular proteins such as collagen
Collagen

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content....
.

Such eosinophilic structures are, in general, composed of protein
Protein

Proteins are organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid Residue ....
.

The stain eosin is usually combined with a stain called hematoxylin to produce a hematoxylin and eosin-stained section
Section

selfref|For the sectioning of Wikipedia articles, see...
 (also called an H&E, HE or H+E section). This is the most widely-used histological stain in medical diagnosis, for example, when a pathologist examines a biopsy
Biopsy

A biopsy is a medical test involving the removal of Cell_s or Biological tissues for examination. It is the removal of tissue from a living subject to determine the presence or extent of a disease....
 of a suspected cancer, the biopsy will have been stained with H&E.

Some structures seen inside cells are described as being eosinophilic, for example, Lewy bodies
Lewy body

Lewy bodies are abnormal aggregates of protein that develop inside nerve cells. They are identified under the microscope when histology is performed on the brain....
, Mallory bodies
Mallory body

Mallory bodies are Pathology inclusions found in the cytoplasm of liver Cell s. ...
.

See also

  • basophilic
    Basophilic

    Basophilic is a technical term used by Histology. It describes the microscopic appearance of cell s and Biological tissues, as seen down the microscope, after a histological section has been stained with a basic dye....
     (affinity to hematoxylln
    Haematoxylin

    Haematoxylin, hematoxylin, Natural Black 1, or C.I. 75290 is extracted from the wood of the logwood tree. When oxidised it forms haematein, a compound with rich blue-purple color, and is used, together with a suitable mordant , to staining cell nuclei prior to examination under a microscope....
    )
  • Eosinophilia
    Eosinophilia

    Eosinophilia is the state of having a high concentration of eosinophils in the blood. The normal concentration is between 0 and 0.5 x 109 eosinophils per litre of blood....