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Eosinophilia
 
 
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Eosinophilia is the state of having a high concentration of eosinophils (eosinophil granulocyte
Eosinophil granulocyte

Eosinophil granulocytes, usually called eosinophils , are white blood cells that are one of the immune system components responsible for combating infection and parasites in vertebrates....
s) in the blood
Blood

Blood is a specialized bodily fluid that delivers necessary substances to the body's Cell s ? such as nutrients and oxygen ? and transports waste products away from those same cells....
. The normal concentration is between 0 and 0.5 x 109 eosinophils per litre
Litre

The litre or liter is a unit of volume. There are two official symbols: the Latin letter L in lower and upper case . The lower case L is often written as a cursive l to avoid confusion with the number 1 in antiqua fonts....
 of blood. Eosinophilia can be reactive (in response to other stimuli such as allergy or infection) or non reactive.

The release of interleukin 5
Interleukin 5

Interleukin 5 or IL-5 is an interleukin produced by T helper cell-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion....
 by T cell
T cell

T cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special receptor on their cell surface called T cell receptors ....
s, mast cell
Mast cell

A mast cell is a resident cell of several types of tissues and contains many Granule rich in histamine and heparin. Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing and defense against pathogens....
s and macrophage
Macrophage

Macrophages are white blood cells within tissues, produced by the division of monocytes. Human macrophages are about 21 micrometres in diameter....
s stimulates the production of eosinophils.








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Encyclopedia


Eosinophilia is the state of having a high concentration of eosinophils (eosinophil granulocyte
Eosinophil granulocyte

Eosinophil granulocytes, usually called eosinophils , are white blood cells that are one of the immune system components responsible for combating infection and parasites in vertebrates....
s) in the blood
Blood

Blood is a specialized bodily fluid that delivers necessary substances to the body's Cell s ? such as nutrients and oxygen ? and transports waste products away from those same cells....
. The normal concentration is between 0 and 0.5 x 109 eosinophils per litre
Litre

The litre or liter is a unit of volume. There are two official symbols: the Latin letter L in lower and upper case . The lower case L is often written as a cursive l to avoid confusion with the number 1 in antiqua fonts....
 of blood. Eosinophilia can be reactive (in response to other stimuli such as allergy or infection) or non reactive.

The release of interleukin 5
Interleukin 5

Interleukin 5 or IL-5 is an interleukin produced by T helper cell-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion....
 by T cell
T cell

T cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special receptor on their cell surface called T cell receptors ....
s, mast cell
Mast cell

A mast cell is a resident cell of several types of tissues and contains many Granule rich in histamine and heparin. Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing and defense against pathogens....
s and macrophage
Macrophage

Macrophages are white blood cells within tissues, produced by the division of monocytes. Human macrophages are about 21 micrometres in diameter....
s stimulates the production of eosinophils.

Causes

Diseases that feature eosinophilia:
  • Hypereosinophilic syndrome
    Hypereosinophilic syndrome

    The hypereosinophilic syndrome is a disease process characterized by a persistently elevated eosinophil count in the blood for at least six months without any recognizable cause after a careful workup, with evidence of involvement of either the heart, nervous system, or bone marrow....
  • Parasitic infections (intestinal helminthiasis)
  • Allergic disorders
    Allergy

    Allergy is a Disorder of the immune system often also referred to as atopy. Allergic reactions occur to Natural environmental substances known as allergens; these reactions are Acquired disorder, predictable and rapid....
     (including eosinophilic esophagitis
    Eosinophilic esophagitis

    Eosinophilic esophagitis is an allergy inflammatory condition of the esophagus. Symptoms are dysphagia, esophageal food bolus obstruction, and heartburn....
    )
  • Some drug reactions, e.g. DRESS syndrome
    DRESS syndrome

    DRESS syndrome stands for Drug Rash with Eosinophilia and Systemic Symptoms. It is also known as Drug Hypersensitivity Syndrome. The symptoms of DRESS syndrome usually begin 1 to 8 weeks after exposure to the offending drug....
  • Cholesterol embolization
  • Churg-Strauss syndrome
    Churg-Strauss syndrome

    Churg-Strauss syndrome is a medium and small vessel autoimmune disease vasculitis, leading to necrosis. It involves mainly the blood vessels of the lungs , gastrointestinal system, and peripheral nerves, but also affects the heart, skin and kidneys....
  • Some forms of chronic myeloid leukaemia
  • Hodgkin's lymphoma
    Hodgkin's lymphoma

    Hodgkin's lymphoma, also known as Hodgkin's disease is a type of lymphoma . It was named after Thomas Hodgkin, who first described abnormalities in the lymph system in 1832....
  • Gleich's syndrome
    Gleich's syndrome

    Gleich's syndrome or episodic angioedema with eosinophilia is a rare disease in which the body swells up episodically , associated with raised antibodies of the IgM type and increased numbers of eosinophil granulocytes, a type of white blood cells, in the blood ....
  • Addison's disease
    Addison's disease

    Addison's disease is a rare endocrine disorder in which the adrenal gland doesn't produce enough steroid hormones . It may develop in children and adults, and may occur as the result many underlying causes....
  • Clonorchis sinensis
    Clonorchis sinensis

    The Clonorchis sinensis is a human liver fluke in the class Trematoda, Phylum Platyhelminthes. This parasite lives in the liver of humans, and is found mainly in the common bile duct and gall bladder, feeding on bile....
    , a type of flatworm
  • Eosinophilia-myalgia syndrome
    Eosinophilia-myalgia syndrome

    Eosinophilia-myalgia syndrome is an incurable and sometimes fatal flu-like neurological condition that is believed to have been caused by ingestion of poorly produced L-tryptophan supplements....
     caused by contaminated tryptophan supplements


See also

  • Eosinophilia-myalgia syndrome
    Eosinophilia-myalgia syndrome

    Eosinophilia-myalgia syndrome is an incurable and sometimes fatal flu-like neurological condition that is believed to have been caused by ingestion of poorly produced L-tryptophan supplements....