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Basophilic is a technical term used by histologists
Histology

Histology is the study of the anatomy of cell and tissue of plants and animals. It is performed by examining a thin slice of tissue under a light microscope or electron microscope....
. It describes the microscopic appearance of cell
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
s and tissue
Biological tissue

Tissue is a cellular organizational level intermediate between cells and a complete organism. Hence, a tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function....
s, as seen down the microscope
Microscope

A microscope is an Laboratory equipment for viewing objects that are too small to be seen by the naked or unaided eye. The science of investigating small objects using such an instrument is called microscopy....
, after a histological section
Histological section

Histology section refers to thin slices of Biological tissue applied to a microscopic slide, usually around 5 to 10 micrometres thick, which are viewed under a microscope....
 has been stained with a basic dye
Dye

A dye can generally be described as a colored substance that has an Chemical affinity to the Wiktionary:substrate to which it is being applied....
. The most common such dye is haematoxylin
Haematoxylin

Haematoxylin, hematoxylin, Natural Black 1, or C.I. 75290 is extracted from the wood of the logwood tree. When oxidised it forms haematein, a compound with rich blue-purple color, and is used, together with a suitable mordant , to staining cell nuclei prior to examination under a microscope....
.

Basophilic describes the appearance of structures seen in histological sections which take up basic dyes. The structures usually stained are those that contain nucleic acid
Nucleic acid

A nucleic acid is a macromolecule composed of chains of monomeric nucleotides. In biochemistry these molecules carry genetic information or form structures within Cell ....
 such as the cell nucleus
Cell nucleus

In cell biology, the nucleus , also sometimes referred to as the "control center", is a membrane-enclosed organelle found in all eukaryote cell ....
 and ribosomes.

Basophils are cells that "love" base
Base (chemistry)

In chemistry, a base is most commonly thought of as an aqueous substance that can accept protons. A base is also often referred to as an alkali if OH- ions are involved....
, and which usually show up deep blue under standard staining techniques (H&E).






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Basophilic is a technical term used by histologists
Histology

Histology is the study of the anatomy of cell and tissue of plants and animals. It is performed by examining a thin slice of tissue under a light microscope or electron microscope....
. It describes the microscopic appearance of cell
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
s and tissue
Biological tissue

Tissue is a cellular organizational level intermediate between cells and a complete organism. Hence, a tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function....
s, as seen down the microscope
Microscope

A microscope is an Laboratory equipment for viewing objects that are too small to be seen by the naked or unaided eye. The science of investigating small objects using such an instrument is called microscopy....
, after a histological section
Histological section

Histology section refers to thin slices of Biological tissue applied to a microscopic slide, usually around 5 to 10 micrometres thick, which are viewed under a microscope....
 has been stained with a basic dye
Dye

A dye can generally be described as a colored substance that has an Chemical affinity to the Wiktionary:substrate to which it is being applied....
. The most common such dye is haematoxylin
Haematoxylin

Haematoxylin, hematoxylin, Natural Black 1, or C.I. 75290 is extracted from the wood of the logwood tree. When oxidised it forms haematein, a compound with rich blue-purple color, and is used, together with a suitable mordant , to staining cell nuclei prior to examination under a microscope....
.

Basophilic describes the appearance of structures seen in histological sections which take up basic dyes. The structures usually stained are those that contain nucleic acid
Nucleic acid

A nucleic acid is a macromolecule composed of chains of monomeric nucleotides. In biochemistry these molecules carry genetic information or form structures within Cell ....
 such as the cell nucleus
Cell nucleus

In cell biology, the nucleus , also sometimes referred to as the "control center", is a membrane-enclosed organelle found in all eukaryote cell ....
 and ribosomes.

Basophils are cells that "love" base
Base (chemistry)

In chemistry, a base is most commonly thought of as an aqueous substance that can accept protons. A base is also often referred to as an alkali if OH- ions are involved....
, and which usually show up deep blue under standard staining techniques (H&E). Specifically, this term refers to:

  • basophil granulocyte
    Basophil granulocyte

    Basophils are the least common of the granulocytes, representing about 0.01% to 0.3% of circulating leukocytes .The name comes from the fact that these leucocytes are basophilic, i.e., they are susceptible to staining by base dyes, as shown in the picture....
    s
  • anterior pituitary basophil
    Anterior pituitary basophil

    An anterior pituitary basophil is a type of cell in the anterior pituitary which manufactures hormones.It is called a basophilic because it readily takes up Base , and typically stains a relatively deep blue or purple....
    s


See also

  • Acidophile (histology)
    Acidophile (histology)

    An acidophile describes is a term used by histologists to describe a particular staining pattern of cells and tissues when using haematoxylin and eosin stains....