David Amaral
Encyclopedia
David G. Amaral, PhD, is a professor of psychiatry
Psychiatry
Psychiatry is the medical specialty devoted to the study and treatment of mental disorders. These mental disorders include various affective, behavioural, cognitive and perceptual abnormalities...

 at the University of California, Davis
University of California, Davis
The University of California, Davis is a public teaching and research university established in 1905 and located in Davis, California, USA. Spanning over , the campus is the largest within the University of California system and third largest by enrollment...

, United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

, and since 1998 has been the research director at the M.I.N.D. Institute, an affiliate of UC Davis, engaged in interdisciplinary research into the causes
Causes of autism
Many causes of autism have been proposed, but understanding of the theory of causation of autism and the other autism spectrum disorders is incomplete. Heritability contributes about 90% of the risk of a child developing autism, but the heritability of autism is complex and typically it is...

 and treatment
Autism therapies
Autism therapies attempt to lessen the deficits and abnormal behaviours associated with autism and other autism spectrum disorders , and to increase the quality of life and functional independence of autistic individuals, especially children. Treatment is typically tailored to the child's needs...

 of autism
Autism
Autism is a disorder of neural development characterized by impaired social interaction and communication, and by restricted and repetitive behavior. These signs all begin before a child is three years old. Autism affects information processing in the brain by altering how nerve cells and their...

 and related neurodevelopmental disorders. Amaral joined the UC Davis faculty as a Professor in the Department of Psychiatry and the Center for Neuroscience and as an investigator at the California Regional Primate Research Center
California National Primate Research Center
The California National Primate Research Center is a United States federal government funded biomedical research facility, dedicated to improving human and animal health, and located on the University of California, Davis, campus...

 in 1991. Since 1995, he has been a professor of psychiatry in the UC Davis School of Medicine, with an appointment to the Center for Neuroscience.

Education

In 1972, Amaral earned his bachelor's degree in psychology
Psychology
Psychology is the study of the mind and behavior. Its immediate goal is to understand individuals and groups by both establishing general principles and researching specific cases. For many, the ultimate goal of psychology is to benefit society...

 from Northwestern University
Northwestern University
Northwestern University is a private research university in Evanston and Chicago, Illinois, USA. Northwestern has eleven undergraduate, graduate, and professional schools offering 124 undergraduate degrees and 145 graduate and professional degrees....

, and in 1977 his PhD in neurobiology and psychology at the University of Rochester
University of Rochester
The University of Rochester is a private, nonsectarian, research university in Rochester, New York, United States. The university grants undergraduate and graduate degrees, including doctoral and professional degrees. The university has six schools and various interdisciplinary programs.The...

. From 1977 to 1980, Amaral was a National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...

 postdoctoral fellow, at the Department of Anatomy & Neurobiology, Washington University School of Medicine, in St. Louis, Missouri
St. Louis, Missouri
St. Louis is an independent city on the eastern border of Missouri, United States. With a population of 319,294, it was the 58th-largest U.S. city at the 2010 U.S. Census. The Greater St...

.

Brain research

A specialist on the organization and functioning of the hippocampus
Hippocampus
The hippocampus is a major component of the brains of humans and other vertebrates. It belongs to the limbic system and plays important roles in the consolidation of information from short-term memory to long-term memory and spatial navigation. Humans and other mammals have two hippocampi, one in...

 and other parts of the primate
Primate
A primate is a mammal of the order Primates , which contains prosimians and simians. Primates arose from ancestors that lived in the trees of tropical forests; many primate characteristics represent adaptations to life in this challenging three-dimensional environment...

 brain
Brain
The brain is the center of the nervous system in all vertebrate and most invertebrate animals—only a few primitive invertebrates such as sponges, jellyfish, sea squirts and starfishes do not have one. It is located in the head, usually close to primary sensory apparatus such as vision, hearing,...

, Amaral has chaired the doctoral program in neuroscience
Neuroscience
Neuroscience is the scientific study of the nervous system. Traditionally, neuroscience has been seen as a branch of biology. However, it is currently an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics,...

 at UC Davis. Amaral has directed over a million dollars worth of research with grants from the National Institute of Mental Health
National Institute of Mental Health
The National Institute of Mental Health is one of 27 institutes and centers that make up the National Institutes of Health...

 (NIMH), which has included primate
Primate
A primate is a mammal of the order Primates , which contains prosimians and simians. Primates arose from ancestors that lived in the trees of tropical forests; many primate characteristics represent adaptations to life in this challenging three-dimensional environment...

 research investigations on the function of the amygdala
Amygdala
The ' are almond-shaped groups of nuclei located deep within the medial temporal lobes of the brain in complex vertebrates, including humans. Shown in research to perform a primary role in the processing and memory of emotional reactions, the amygdalae are considered part of the limbic system.-...

, a brain region associated with emotion processing. Much of his research at the M.I.N.D. Institute revolves around the function of the amygdala and the hippocampal
Hippocampus
The hippocampus is a major component of the brains of humans and other vertebrates. It belongs to the limbic system and plays important roles in the consolidation of information from short-term memory to long-term memory and spatial navigation. Humans and other mammals have two hippocampi, one in...

 complex, and their respective roles in the pathology of autism.

Amaral investigated "Postmortem Neuroanatomical Evaluation of the Amygdaloid Complex in Autism"; his earlier studies detected alterations in the amygdala, which itself underlies the social and emotional abnormalities in autism. Amaral is attempting to evaluate his hypothesis by analyzing the atypical neural organization in individuals with autism.

M.I.N.D. Institute

The M.I.N.D. Institute, under Amaral's direction since its inception, was founded by UC Davis in collaboration with the parents of children diagnosed with autism spectrum disorders. Amaral's research team is dedicated to understanding and conquering autism, which impairs the ability of people to interact with other people. The partnership between the parents and Amaral's team of researchers secured $34 million in funding from the California legislature, primarily for research purposes. After raising additional funds and building a state-of-the-art facility in Sacramento, California
Sacramento, California
Sacramento is the capital city of the U.S. state of California and the county seat of Sacramento County. It is located at the confluence of the Sacramento River and the American River in the northern portion of California's expansive Central Valley. With a population of 466,488 at the 2010 census,...

, the institute touts itself as the premier autism fundraising and research center in the world.

Recognition

Amaral's awards include the McKnight Foundation
McKnight Foundation
The McKnight Foundation is a philanthropic organization based in Minneapolis, Minnesota in the United States. The foundation's interests lie in the environment, the arts, community development, and other areas....

 Scholars Award, 1981, the Sloan Foundation Fellow, 1983, and the National Institute of Mental Health
National Institute of Mental Health
The National Institute of Mental Health is one of 27 institutes and centers that make up the National Institutes of Health...

 (NIMH) Merit Award, 1989 and 1993. He is the first holder of the Beneto Foundation Chair, an endowed position at UC Davis created by the Beneto Foundation of Sacramento.

External links

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