Datura wrightii
Encyclopedia
Datura wrightii or Sacred Datura is the name of a poison
Poison
In the context of biology, poisons are substances that can cause disturbances to organisms, usually by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by an organism....

ous perennial plant
Perennial plant
A perennial plant or simply perennial is a plant that lives for more than two years. The term is often used to differentiate a plant from shorter lived annuals and biennials. The term is sometimes misused by commercial gardeners or horticulturalists to describe only herbaceous perennials...

 and ornamental
Ornamental plant
Ornamental plants are plants that are grown for decorative purposes in gardens and landscape design projects, as house plants, for cut flowers and specimen display...

 flower of southwestern North America
North America
North America is a continent wholly within the Northern Hemisphere and almost wholly within the Western Hemisphere. It is also considered a northern subcontinent of the Americas...

. It is sometimes used as a hallucinogen
Psychedelics, dissociatives and deliriants
This general group of pharmacological agents can be divided into three broad categories: psychedelics, dissociatives, and deliriants. These classes of psychoactive drugs have in common that they can cause subjective changes in perception, thought, emotion and consciousness...

. Datura wrightii is classified as a deliriant
Deliriant
The deliriants are a special class of acetylcholine-inhibitor hallucinogen. The term was introduced by David F. Duncan and Robert S...

 and an anticholinergic
Anticholinergic
An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system. An example of an anticholinergic is dicycloverine, and the classic example is atropine....

.

It is a vigorous herbaceous perennial
Perennial plant
A perennial plant or simply perennial is a plant that lives for more than two years. The term is often used to differentiate a plant from shorter lived annuals and biennials. The term is sometimes misused by commercial gardeners or horticulturalists to describe only herbaceous perennials...

 that grows 30 cm to 1.5 m tall and wide. The leaves are broad and rounded at the base, tapering to a point, often with wavy margins. The flowers are the most striking feature, being sweetly fragrant white trumpets up to 20 cm (8 inches) long, often tinted purple, especially at the margin. There are five narrow points spaced symmetrically around the rim. It can bloom from April to October. In clear weather, flowers open at nearly full dark and wither a few hours after sunrise the following morning; in cloudy weather, they may open earlier and last longer.

The seeds are borne in a spiny, globular capsule 3 to 4 cm in diameter, which opens when fully ripe.

Datura wrightii is found in northern Mexico
Mexico
The United Mexican States , commonly known as Mexico , is a federal constitutional republic in North America. It is bordered on the north by the United States; on the south and west by the Pacific Ocean; on the southeast by Guatemala, Belize, and the Caribbean Sea; and on the east by the Gulf of...

 and the adjoining U. S.
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 states, as far north as southern Utah, in open land with well-drained soils. It is also commonly planted as an ornamental, especially in xeriscapes.

The name commemorates the botanist Charles Wright
Charles Wright (botanist)
Charles Wright was an American botanist.Wright was born in Wethersfield, Connecticut, the son of James Wright and Mary née Goodrich. He studied classics and mathematics at Yale, and in October 1835 moved to Natchez, Mississippi to tutor a plantation owner's family...

.

Other names

In the U.S. it is sometimes called (Western) Jimsonweed because of its resemblance to Datura stramonium
Datura stramonium
Datura stramonium, known by the common names Jimson weed, devil's trumpet, devil's weed, thorn apple, tolguacha, Jamestown weed, stinkweed, locoweed, datura, pricklyburr, devil's cucumber, Hell's Bells, moonflower and, in South Africa, malpitte and mad seeds, is a common weed in the...

. Anglophone
English-speaking world
The English-speaking world consists of those countries or regions that use the English language to one degree or another. For more information, please see:Lists:* List of countries by English-speaking population...

 settlers in California
California
California is a state located on the West Coast of the United States. It is by far the most populous U.S. state, and the third-largest by land area...

 often called it "Indian whiskey" because of its ritual intoxicating use by many tribes; the name "sacred datura" has the same origin. Other common names include "Indian apple" and "nightshade" (not to be confused with Solanum
Solanum
Solanum, the nightshades, horsenettles and relatives, is a large and diverse genus of annual and perennial plants. They grow as forbs, vines, subshrubs, shrubs, and small trees, and often have attractive fruit and flowers. Many formerly independent genera like Lycopersicon or Cyphomandra are...

). The Tongva call it manit and the Chumash momoy. Mexicans call this and similar species tolguacha or toloache.

The scientific name has frequently been given as Datura meteloides Dunal
Michel Félix Dunal
Michel Felix Dunal was a French botanist. He was professor of botany in Montpellier, France. He held the chair of Medical Natural History from 1816 to 1819...

, but this name is actually a synonym of D. inoxia
Datura inoxia
Datura inoxia is a species in the family Solanaceae. It is native to Central and South America, and introduced in Africa, Asia, Australia and Europe. The scientific name is often cited as D. innoxia...

Mill.
Philip Miller
Philip Miller FRS was a Scottish botanist.Miller was chief gardener at the Chelsea Physic Garden from 1722 until he was pressured to retire shortly before his death...

, a Mexican plant with a narrower flower having 10 rather than 5 "teeth" at the rim.

Toxicity

All parts of Datura plants contain dangerous levels of poison and may be fatal if ingested by humans or other animals, including livestock and pets. In some places it is prohibited to buy, sell or cultivate Datura plants.

Religious

Datura wrightii is sacred to some native Americans
Native Americans in the United States
Native Americans in the United States are the indigenous peoples in North America within the boundaries of the present-day continental United States, parts of Alaska, and the island state of Hawaii. They are composed of numerous, distinct tribes, states, and ethnic groups, many of which survive as...

 and has been used in ceremonies and rites of passage by Chumash, Tongva, and others. Among the Chumash, when a boy was 8 years old, his mother gave him a preparation of momoy to drink. This was supposed to be a spiritual challenge to the boy to help him develop the spiritual wellbeing that is required to become a man. Not all of the boys survived. They believed momoy was a spiritual plant that helps with spiritual wellbeing among adults also. For instance, during a frightening situation, such as when seeing a coyote walk like a man, a leaf of momoy was sucked to help keep the soul in the body. The plant was also used to tell the future, especially when gambling.

Recreational

Datura wrightii has also been used to induce hallucination for recreational purposes. Ingestion of plant material can induce auditory and visual hallucinations similar to those of Datura stramonium
Datura stramonium
Datura stramonium, known by the common names Jimson weed, devil's trumpet, devil's weed, thorn apple, tolguacha, Jamestown weed, stinkweed, locoweed, datura, pricklyburr, devil's cucumber, Hell's Bells, moonflower and, in South Africa, malpitte and mad seeds, is a common weed in the...

, with the active compounds being concentrated in the seedpods and roots; concentrations vary widely between samples, and onset is slow. This makes dosage estimation a difficult and adds further risk to the administration of material that already has potentially lethal side effects. Scopolamine
Scopolamine
Scopolamine, also known as levo-duboisine, and hyoscine, is a tropane alkaloid drug with muscarinic antagonist effects. It is among the secondary metabolites of plants from Solanaceae family of plants, such as henbane, jimson weed and Angel's Trumpets , and corkwood...

 is the primary active molecule; it is related to atropine
Atropine
Atropine is a naturally occurring tropane alkaloid extracted from deadly nightshade , Jimson weed , mandrake and other plants of the family Solanaceae. It is a secondary metabolite of these plants and serves as a drug with a wide variety of effects...

, with a similar, largely anticholinergic
Anticholinergic
An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system. An example of an anticholinergic is dicycloverine, and the classic example is atropine....

 activity. Effects may include dry mouth, hyperthermia
Hyperthermia
Hyperthermia is an elevated body temperature due to failed thermoregulation. Hyperthermia occurs when the body produces or absorbs more heat than it can dissipate...

, profuse sweating, drowsiness, lethargy and anteriograde amnesia - along with the before-mentioned hallucinations and sensory distortions. These compounds also induce a profound dilatation of the pupils and suppress eye saccades, resulting in considerable degradation of visual acuity, often to the point of functional blindness. This may persist, to a reduced degree, for days. The combined effect may result a panic state in the user, a particularly dangerous situation in someone temporarily deprived of useful vision; users are prone to serious accidental injury. Scopolamine induces respiratory depression at hallucinogenic doses. The combination of anesthesia (in the hospital) and Datura is usually fatal due to combined respiratory depression. Seizure
Seizure
An epileptic seizure, occasionally referred to as a fit, is defined as a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain". The outward effect can be as dramatic as a wild thrashing movement or as mild as a brief loss of awareness...

s and fevers as high as 43 C (110°F) have been reported.

External links

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