Databases for oncogenomic research
Encyclopedia
Databases for oncogenomic research are biological databases dedicated to cancer
data and oncogenomic research
. They can be a primary source of cancer data, offer a certain level of analysis (processed data) or even offer online data mining
.
The table below gives an overview of databases for that serve specifically for oncogenomic research. Note that this is not a comprehensive list and does not contain databases that have a generic focus. You may find databases containg cancer data among the List of biological databases or Microarray databases
.
Notes
Cancer
Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...
data and oncogenomic research
Oncogenomics
Oncogenomics is relatively new sub-field of genomics, which applies high throughput technologies to characterize genes associated with cancer. Oncogenomics is synonymous with "cancer genomics". Cancer is a genetic disease caused by accumulation of mutations to DNA leading to unrestrained cell...
. They can be a primary source of cancer data, offer a certain level of analysis (processed data) or even offer online data mining
Data mining
Data mining , a relatively young and interdisciplinary field of computer science is the process of discovering new patterns from large data sets involving methods at the intersection of artificial intelligence, machine learning, statistics and database systems...
.
The table below gives an overview of databases for that serve specifically for oncogenomic research. Note that this is not a comprehensive list and does not contain databases that have a generic focus. You may find databases containg cancer data among the List of biological databases or Microarray databases
Microarray databases
The term microarray database is usually used to describe a repository containing microarray gene expression data. The key features of a microarray database are to store the measurement data, manage a searchable index, and make the data available to other applications for analysis and interpretation...
.
Database | Institute / Organization | Alteration Types | Primary Source The database is the publication site for (some of) its cancer raw data | Processed Data The database contains cancer data at a certain level of analysis (non-raw data) | Organisms | Cell lines The database also contains cell line data | Public Data The database contains cancer data that is available for everyone | Restricted Data The database contains cancer data that is only available under some restriction |
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Catalogue Of Somatic Mutations In Cancer (COSMIC) COSMIC cancer database COSMIC is an online database of somatically acquired mutations found in human cancer. Somatic mutations are those that occur in non-germline cells that are not inherited by children... → |
Wellcome Trust Sanger Institute, UK | Mutation Mutation In molecular biology and genetics, mutations are changes in a genomic sequence: the DNA sequence of a cell's genome or the DNA or RNA sequence of a virus. They can be defined as sudden and spontaneous changes in the cell. Mutations are caused by radiation, viruses, transposons and mutagenic... |
Human Human Humans are the only living species in the Homo genus... |
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International Cancer Genome Consortium International Cancer Genome Consortium The International Cancer Genome Consortium is a voluntary scientific organization that provides a forum for collaboration among the world's leading cancer and genomic researchers.... → |
Worldwide World World is a common name for the whole of human civilization, specifically human experience, history, or the human condition in general, worldwide, i.e. anywhere on Earth.... |
Copy number, Mutation Mutation In molecular biology and genetics, mutations are changes in a genomic sequence: the DNA sequence of a cell's genome or the DNA or RNA sequence of a virus. They can be defined as sudden and spontaneous changes in the cell. Mutations are caused by radiation, viruses, transposons and mutagenic... , Gene Expression Gene expression Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as ribosomal RNA , transfer RNA or small nuclear RNA genes, the product is a functional RNA... |
Human Human Humans are the only living species in the Homo genus... |
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Integrative Oncogenomics Cancer Browser (IntOGen) → | Universitat Pompeu Fabra, Spain Spain Spain , officially the Kingdom of Spain languages]] under the European Charter for Regional or Minority Languages. In each of these, Spain's official name is as follows:;;;;;;), is a country and member state of the European Union located in southwestern Europe on the Iberian Peninsula... |
Copy number, Mutation Mutation In molecular biology and genetics, mutations are changes in a genomic sequence: the DNA sequence of a cell's genome or the DNA or RNA sequence of a virus. They can be defined as sudden and spontaneous changes in the cell. Mutations are caused by radiation, viruses, transposons and mutagenic... , Gene Expression Gene expression Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as ribosomal RNA , transfer RNA or small nuclear RNA genes, the product is a functional RNA... |
Human Human Humans are the only living species in the Homo genus... |
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Mouse Retrovirus Tagged Cancer Gene Database → | Institute of Molecular and Cell Biology Institute of Molecular and Cell Biology (Singapore) The Institute of Molecular and Cell Biology is an autonomous research institute of the Agency for Science, Technology and Research in Singapore... , Singapore Singapore Singapore , officially the Republic of Singapore, is a Southeast Asian city-state off the southern tip of the Malay Peninsula, north of the equator. An island country made up of 63 islands, it is separated from Malaysia by the Straits of Johor to its north and from Indonesia's Riau Islands by the... |
Mutations | Mouse | |||||
Mouse Tumor Biology Database →Only contains references to biological data | The Jackson Laboratory, USA | Copy number, Mutation Mutation In molecular biology and genetics, mutations are changes in a genomic sequence: the DNA sequence of a cell's genome or the DNA or RNA sequence of a virus. They can be defined as sudden and spontaneous changes in the cell. Mutations are caused by radiation, viruses, transposons and mutagenic... , Methylation Methylation In the chemical sciences, methylation denotes the addition of a methyl group to a substrate or the substitution of an atom or group by a methyl group. Methylation is a form of alkylation with, to be specific, a methyl group, rather than a larger carbon chain, replacing a hydrogen atom... , Gene Expression Gene expression Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as ribosomal RNA , transfer RNA or small nuclear RNA genes, the product is a functional RNA... |
Mouse | |||||
OncoDB.HCC → | Academia Sinica Academia Sinica The Academia Sinica , headquartered in the Nangang District of Taipei, is the national academy of Taiwan. It supports research activities in a wide variety of disciplines, ranging from mathematical and physical sciences, to life sciences, and to humanities and social sciences.Academia Sinica has... , Taiwan Taiwan Taiwan , also known, especially in the past, as Formosa , is the largest island of the same-named island group of East Asia in the western Pacific Ocean and located off the southeastern coast of mainland China. The island forms over 99% of the current territory of the Republic of China following... |
Copy number, Gene Expression Gene expression Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as ribosomal RNA , transfer RNA or small nuclear RNA genes, the product is a functional RNA... , QTL |
Human Human Humans are the only living species in the Homo genus... , Mouse, Rat |
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Oncomine → | Compendia Bioscience, Inc., USA | Gene Expression Gene expression Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as ribosomal RNA , transfer RNA or small nuclear RNA genes, the product is a functional RNA... |
Human Human Humans are the only living species in the Homo genus... |
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Oncoreveal → | Boğaziçi University Bogaziçi University Boğaziçi University is a public university located on the European side of the Bosphorus strait in Istanbul, Turkey. It has five faculties and two schools offering undergraduate degrees, and six institutes offering graduate degrees... , Turkey Turkey Turkey , known officially as the Republic of Turkey , is a Eurasian country located in Western Asia and in East Thrace in Southeastern Europe... |
Gene Expression Gene expression Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as ribosomal RNA , transfer RNA or small nuclear RNA genes, the product is a functional RNA... |
Human Human Humans are the only living species in the Homo genus... |
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Progenetix → | Universität Zürich, Switzerland Switzerland Switzerland name of one of the Swiss cantons. ; ; ; or ), in its full name the Swiss Confederation , is a federal republic consisting of 26 cantons, with Bern as the seat of the federal authorities. The country is situated in Western Europe,Or Central Europe depending on the definition.... |
Copy number | Human Human Humans are the only living species in the Homo genus... |
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The Cancer Genome Atlas The Cancer Genome Atlas The Cancer Genome Atlas is a project to catalogue genetic mutations responsible for cancer, using genome analysis techniques started in 2005... → |
National Cancer Institute National Cancer Institute The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S... , USA |
Copy number, Mutation Mutation In molecular biology and genetics, mutations are changes in a genomic sequence: the DNA sequence of a cell's genome or the DNA or RNA sequence of a virus. They can be defined as sudden and spontaneous changes in the cell. Mutations are caused by radiation, viruses, transposons and mutagenic... , Methylation Methylation In the chemical sciences, methylation denotes the addition of a methyl group to a substrate or the substitution of an atom or group by a methyl group. Methylation is a form of alkylation with, to be specific, a methyl group, rather than a larger carbon chain, replacing a hydrogen atom... , Gene Expression Gene expression Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as ribosomal RNA , transfer RNA or small nuclear RNA genes, the product is a functional RNA... , miRNA expression |
Human Human Humans are the only living species in the Homo genus... |
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CancerResource CancerResource CancerResource is database of drug-target relationships related to cancer.... → |
University Medicine Berlin, Germany | |||||||
Roche Cancer Genome Database (RCGDB) http://rcgdb.bioinf.uni-sb.de/MutomeWeb/ | Roche Diagnostics, Penzberg, Germany | |||||||
See also
- Cancer ResearchCancer researchCancer research is basic research into cancer in order to identify causes and develop strategies for prevention, diagnosis, treatments and cure....
- List of biological databases
- Microarray databasesMicroarray databasesThe term microarray database is usually used to describe a repository containing microarray gene expression data. The key features of a microarray database are to store the measurement data, manage a searchable index, and make the data available to other applications for analysis and interpretation...
- OncogenomicsOncogenomicsOncogenomics is relatively new sub-field of genomics, which applies high throughput technologies to characterize genes associated with cancer. Oncogenomics is synonymous with "cancer genomics". Cancer is a genetic disease caused by accumulation of mutations to DNA leading to unrestrained cell...
- OncologyOncologyOncology is a branch of medicine that deals with cancer...
Notes