God gene
Encyclopedia
The God gene hypothesis proposes that a specific gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

 (VMAT2
VMAT2
The vesicular monoamine transporter 2 also known as solute carrier family 18 member 2 is a protein that in humans is encoded by the SLC18A2 gene...

) predisposes humans towards spiritual
Spirituality
Spirituality can refer to an ultimate or an alleged immaterial reality; an inner path enabling a person to discover the essence of his/her being; or the “deepest values and meanings by which people live.” Spiritual practices, including meditation, prayer and contemplation, are intended to develop...

 or mystic
Mysticism
Mysticism is the knowledge of, and especially the personal experience of, states of consciousness, i.e. levels of being, beyond normal human perception, including experience and even communion with a supreme being.-Classical origins:...

 experiences. The idea has been postulated by geneticist
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....

 Dean Hamer
Dean Hamer
Dr. Dean Hamer is an American geneticist, author, and filmmaker. He is known for his contributions to biotechnology and AIDS prevention, his research on the genetics of human behavior including sexual orientation and spirituality, and his popular books and documentaries on a wide range of...

, the director of the Gene Structure and Regulation Unit at the U.S.
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 National Cancer Institute
National Cancer Institute
The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S...

, and author of the 2005 book The God Gene: How Faith is Hardwired into our Genes.

The God gene hypothesis is based on a combination of behavioral genetic, neurobiological and psychological studies. The major arguments of the theory are: (1) spirituality can be quantified
Quantitative property
A quantitative property is one that exists in a range of magnitudes, and can therefore be measured with a number. Measurements of any particular quantitative property are expressed as a specific quantity, referred to as a unit, multiplied by a number. Examples of physical quantities are distance,...

 by psychometric measurements; (2) the underlying tendency to spirituality is partially heritable; (3) part of this heritability can be attributed to the gene VMAT2
VMAT2
The vesicular monoamine transporter 2 also known as solute carrier family 18 member 2 is a protein that in humans is encoded by the SLC18A2 gene...

; (4) this gene acts by altering monoamine levels; and (5) spiritual individuals are favored by natural selection
Natural selection
Natural selection is the nonrandom process by which biologic traits become either more or less common in a population as a function of differential reproduction of their bearers. It is a key mechanism of evolution....

 because they are provided with an innate sense of optimism, the latter producing positive effects at either a physical and psychological level.

A number of scientists and researchers are highly critical of this theory; Carl Zimmer, writing in Scientific American
Scientific American
Scientific American is a popular science magazine. It is notable for its long history of presenting science monthly to an educated but not necessarily scientific public, through its careful attention to the clarity of its text as well as the quality of its specially commissioned color graphics...

, questions why "Hamer rushed into print with this book before publishing his results in a credible scientific journal."
In his book, Hamer also writes "Just because spirituality is partly genetic doesn't mean it is hardwired."

Proposal

According to this hypothesis, the God gene (VMAT2
VMAT2
The vesicular monoamine transporter 2 also known as solute carrier family 18 member 2 is a protein that in humans is encoded by the SLC18A2 gene...

) is a physiological arrangement that produces the sensations associated, by some, with mystic
Mysticism
Mysticism is the knowledge of, and especially the personal experience of, states of consciousness, i.e. levels of being, beyond normal human perception, including experience and even communion with a supreme being.-Classical origins:...

 experiences, including the presence of God
Presence of God
Presence of God is a term used in Catholic theology and devotion.In theology, it refers to the belief that God is present by His Essence everywhere and in all things by reason of His Immensity...

 or others, or more specifically spirituality
Spirituality
Spirituality can refer to an ultimate or an alleged immaterial reality; an inner path enabling a person to discover the essence of his/her being; or the “deepest values and meanings by which people live.” Spiritual practices, including meditation, prayer and contemplation, are intended to develop...

 as a state of mind (i.e. it does not encode or cause belief
Belief
Belief is the psychological state in which an individual holds a proposition or premise to be true.-Belief, knowledge and epistemology:The terms belief and knowledge are used differently in philosophy....

 in God
God
God is the English name given to a singular being in theistic and deistic religions who is either the sole deity in monotheism, or a single deity in polytheism....

 itself in spite of the "God gene" moniker).

Based on research by psychologist Robert Cloninger, this tendency toward spirituality is quantified by the self-transcendence scale, which is composed of three sub-sets: "self-forgetfulness" (as in the tendency to become totally absorbed in some activity, such as reading); "transpersonal identification" (a feeling of connectedness to a larger universe); and "mysticism" (an openness to believe things not literally provable, such as ESP
Extra-sensory perception
Extrasensory perception involves reception of information not gained through the recognized physical senses but sensed with the mind. The term was coined by Frederic Myers, and adopted by Duke University psychologist J. B. Rhine to denote psychic abilities such as telepathy, clairaudience, and...

). Cloninger suggests that taken together, these measurements are a reasonable way to quantify
Quantitative property
A quantitative property is one that exists in a range of magnitudes, and can therefore be measured with a number. Measurements of any particular quantitative property are expressed as a specific quantity, referred to as a unit, multiplied by a number. Examples of physical quantities are distance,...

 (make measurable) how spiritual
Spirituality
Spirituality can refer to an ultimate or an alleged immaterial reality; an inner path enabling a person to discover the essence of his/her being; or the “deepest values and meanings by which people live.” Spiritual practices, including meditation, prayer and contemplation, are intended to develop...

 someone is feeling.

The self-transcendence measure was shown to be heritable by classical twin studies conducted by Lindon Eaves and Nicholas Martin. Interestingly, these studies show that specific religious beliefs (such as belief in Jesus) have no genetic basis and are instead memes, that is cultural units transmitted by non genetic means, as by imitation.

In order to identify some of the specific genes involved in self-transcendence, Hamer analyzed DNA and personality score data from over 1000 individuals and identified one particular locus, VMAT2, with a significant correlation. VMAT2 codes for a vesicular monoamine transporter that plays a key role in regulating the levels of the brain chemicals serotonin, dopamine and norepinephrine. These monoamine transmitters are in turn postulated to play an important role in regulating the brain activities associated with mystic beliefs.

What evolutionary advantage this may convey, or what advantageous effect it is a side effect of, are questions that are yet to be fully explored. However, Dr. Hamer has hypothesized that self-transcendence makes people more optimistic, which makes them healthier and likely to have more children.

Scientific criticism

Although it is always difficult to determine the many interacting functions of a gene, VMAT2
VMAT2
The vesicular monoamine transporter 2 also known as solute carrier family 18 member 2 is a protein that in humans is encoded by the SLC18A2 gene...

 appears to be involved in the transport of monoamine neurotransmitters across the synapses of the brain. PZ Myers
PZ Myers
Paul Zachary "PZ" Myers is an American biology professor at the University of Minnesota Morris and the author of the Pharyngula science blog. He is currently an associate professor of biology at UMM, works with zebrafish in the field of evolutionary developmental biology , and also cultivates an...

 argues: "It's a pump. A teeny-tiny pump responsible for packaging a neurotransmitter for export during brain activity. Yes, it's important, and it may even be active and necessary during higher order processing, like religious thought. But one thing it isn't is a 'god gene.'"

Carl Zimmer
Carl Zimmer
Carl Zimmer is a popular science writer and blogger, especially regarding the study of evolution and parasites. He has written several books and contributes science essays to publications such as The New York Times and Discover...

 claimed that, given the low explanatory power of VMAT2, it can be characterized as a gene that accounts for less than one percent of the variance of self-transcendence scores. These, Zimmer says, can signify anything from belonging to the green party to believing in ESP. Zimmer also points out that the God Gene theory is based on only one unpublished, unreplicated study. However Hamer notes that the importance of the VMAT2 finding is not that it explains all spiritual or religious feelings, but rather that it points the way toward one neurobiological pathway that may be important.

Religious response

John Polkinghorne
John Polkinghorne
John Charlton Polkinghorne KBE FRS is an English theoretical physicist, theologian, writer, and Anglican priest. He was professor of Mathematical physics at the University of Cambridge from 1968 to 1979, when he resigned his chair to study for the priesthood, becoming an ordained Anglican priest...

, an Anglican priest, member of the Royal Society
Royal Society
The Royal Society of London for Improving Natural Knowledge, known simply as the Royal Society, is a learned society for science, and is possibly the oldest such society in existence. Founded in November 1660, it was granted a Royal Charter by King Charles II as the "Royal Society of London"...

 and Canon
Canon (priest)
A canon is a priest or minister who is a member of certain bodies of the Christian clergy subject to an ecclesiastical rule ....

 Theologian
Theology
Theology is the systematic and rational study of religion and its influences and of the nature of religious truths, or the learned profession acquired by completing specialized training in religious studies, usually at a university or school of divinity or seminary.-Definition:Augustine of Hippo...

 at Liverpool Cathedral
Liverpool Cathedral
Liverpool Cathedral is the Church of England cathedral of the Diocese of Liverpool, built on St James's Mount in Liverpool and is the seat of the Bishop of Liverpool. Its official name is the Cathedral Church of Christ in Liverpool but it is dedicated to Christ and the Blessed Virgin...

, was asked for a comment on Hamer's theory by the British
United Kingdom
The United Kingdom of Great Britain and Northern IrelandIn the United Kingdom and Dependencies, other languages have been officially recognised as legitimate autochthonous languages under the European Charter for Regional or Minority Languages...

 national daily newspaper, The Daily Telegraph
The Daily Telegraph
The Daily Telegraph is a daily morning broadsheet newspaper distributed throughout the United Kingdom and internationally. The newspaper was founded by Arthur B...

. He replied: "The idea of a God gene goes against all my personal theological convictions. You can't cut faith down to the lowest common denominator of genetic survival. It shows the poverty of reductionist
Reductionism
Reductionism can mean either an approach to understanding the nature of complex things by reducing them to the interactions of their parts, or to simpler or more fundamental things or a philosophical position that a complex system is nothing but the sum of its parts, and that an account of it can...

 thinking."

Walter Houston, the chaplain
Chaplain
Traditionally, a chaplain is a minister in a specialized setting such as a priest, pastor, rabbi, or imam or lay representative of a religion attached to a secular institution such as a hospital, prison, military unit, police department, university, or private chapel...

 of Mansfield College, Oxford
Mansfield College, Oxford
Mansfield College is one of the constituent colleges of the University of Oxford in England. Of the colleges that accept both undergraduate and graduate students Mansfield College is one of the smallest, comprising approximately 210 undergraduates, 130 graduates, 35 visiting students and 50...

, and a fellow in theology
Theology
Theology is the systematic and rational study of religion and its influences and of the nature of religious truths, or the learned profession acquired by completing specialized training in religious studies, usually at a university or school of divinity or seminary.-Definition:Augustine of Hippo...

, told the Telegraph: "Religious belief is not just related to a person's constitution; it's related to society, tradition, character—everything's involved. Having a gene that could do all that seems pretty unlikely to me."

Hamer responded that the existence of such a gene would not be incompatible with the existence of a personal God: "Religious believers can point to the existence of God genes as one more sign of the creator's ingenuity—a clever way to help humans acknowledge and embrace a divine presence."

Hamer repeatedly notes in his book that, "This book is about whether God genes exist, not about whether there is a God."

See also

  • VMAT2
    VMAT2
    The vesicular monoamine transporter 2 also known as solute carrier family 18 member 2 is a protein that in humans is encoded by the SLC18A2 gene...

  • Neurotheology
    Neurotheology
    Neurotheology, also known as spiritual neuroscience, is the study of correlations of neural phenomena with subjective experiences of spirituality and hypotheses to explain these phenomena....

  • Origin of religion
    Evolutionary origin of religions
    The evolutionary origin of religions theorizes about the emergence of religious behavior during the course of human evolution.- Nonhuman religious behavior :...

  • Cognitive science of religion
    Cognitive science of religion
    Cognitive science of religion is the study of religious thought and behavior from the perspective of the cognitive and evolutionary sciences. The field employs methods and theories from a very broad range of disciplines, including: cognitive psychology, evolutionary psychology, cognitive...


External links

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