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Bone remodeling

 

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Bone remodeling



 
 
Bone remodeling is a life long process where old bone
Bone

Bones are rigid organ that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red blood cell and white blood cells and store minerals....
 is removed from the skeleton
Skeleton

In biology, a skeleton is a rigid framework that provides protection and structure in many types of animal, particularly those of the phylum Chordata and of the superphylum Ecdysozoa....
 (a sub-process called bone resorption
Bone resorption

Bone resorption is the process by which osteoclasts break down bone and release the minerals, resulting in a transfer of calcium from bone fluid to the blood....
) and new bone is added (a sub-process called ossification
Ossification

Ossification is the process of bone formation, in which connective tissues, such as cartilage are turned to bone or bone-like tissue. The ossified tissue is invaginated with blood vessels....
 or bone formation). These processes also control the reshaping or replacement of bone during growth
Growth

Growth refers to an increase in some quantity over time. The quantity can be physical or abstract . It can also refer to the mode of growth, i.e....
 and following injuries. Remodeling responds to functional demands and muscle attachments. As a result bone is added where needed and removed where it is not required.

In the first year of life, almost 100% of the skeleton is replaced.






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Encyclopedia


Bone remodeling is a life long process where old bone
Bone

Bones are rigid organ that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red blood cell and white blood cells and store minerals....
 is removed from the skeleton
Skeleton

In biology, a skeleton is a rigid framework that provides protection and structure in many types of animal, particularly those of the phylum Chordata and of the superphylum Ecdysozoa....
 (a sub-process called bone resorption
Bone resorption

Bone resorption is the process by which osteoclasts break down bone and release the minerals, resulting in a transfer of calcium from bone fluid to the blood....
) and new bone is added (a sub-process called ossification
Ossification

Ossification is the process of bone formation, in which connective tissues, such as cartilage are turned to bone or bone-like tissue. The ossified tissue is invaginated with blood vessels....
 or bone formation). These processes also control the reshaping or replacement of bone during growth
Growth

Growth refers to an increase in some quantity over time. The quantity can be physical or abstract . It can also refer to the mode of growth, i.e....
 and following injuries. Remodeling responds to functional demands and muscle attachments. As a result bone is added where needed and removed where it is not required.

In the first year of life, almost 100% of the skeleton is replaced. In adults, remodeling proceeds at about 10% per year.

An imbalance in the regulation of bone remodeling's two sub-processes, bone resorption and bone formation, results in many metabolic bone diseases, such as osteoporosis.

See also

  • Bone healing
    Bone healing

    Bone healing, or fracture healing, is a Cell growth physiological process in which the body facilitates the repair of a bone fracture....