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Balance disorder



 
 
A balance disorder is a disturbance that causes an individual to feel unsteady, giddy, woozy, or have a sensation of movement, spinning, or floating. Balance
Equilibrioception

Equilibrioception or sense of balance is one of the physiology senses. It helps prevent humans and animals from falling over when walking or standing still....
 is the result of a number of body systems working together. Specifically, in order to achieve balance, the eyes (visual system), ears (vestibular system
Vestibular system

The vestibular system, which contributes to our balance and our sense of spatial orientation, is the sensory system that provides the dominant input about movement and equilibrioception....
) and the body's sense of where it is in space (proprioception
Proprioception

Proprioception ; from Latin proprius, meaning "one's own" and perception) is the sense of the relative position of neighbouring parts of the body....
) need to be intact. Also the brain, which compiles this information, needs to be functioning normally.

semicircular canals, found within the vestibular apparatus, let us know when we are in a rotary (circular) motion.






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A balance disorder is a disturbance that causes an individual to feel unsteady, giddy, woozy, or have a sensation of movement, spinning, or floating. Balance
Equilibrioception

Equilibrioception or sense of balance is one of the physiology senses. It helps prevent humans and animals from falling over when walking or standing still....
 is the result of a number of body systems working together. Specifically, in order to achieve balance, the eyes (visual system), ears (vestibular system
Vestibular system

The vestibular system, which contributes to our balance and our sense of spatial orientation, is the sensory system that provides the dominant input about movement and equilibrioception....
) and the body's sense of where it is in space (proprioception
Proprioception

Proprioception ; from Latin proprius, meaning "one's own" and perception) is the sense of the relative position of neighbouring parts of the body....
) need to be intact. Also the brain, which compiles this information, needs to be functioning normally.

Normal Balance Functioning

Balance Disorder Illustration A
Balance Disorder Illustration B
Balance Disorder Illustration C
The semicircular canals, found within the vestibular apparatus, let us know when we are in a rotary (circular) motion. The semicircular canals are fluid-filled. Motion of the fluid tells us if we are moving. The vestibule is the region of the inner ear where the semicircular canals converge, close to the cochlea
Cochlea

The cochlea is the auditory portion of the inner ear. Its core component is the Organ of Corti, the sensory organ of hearing , which is distributed along the partition separating fluid chambers in the coiled tapered tube of the cochlea....
 (the hearing organ). The vestibular system works with the visual system to keep objects in focus when the head is moving. This is called the vestibulo-ocular reflex (VOR).

Movement of fluid in the semicircular canals signals the brain about the direction and speed of rotation of the head - for example, whether we are nodding our head up and down or looking from right to left. Each semicircular canal has a bulbed end, or enlarged portion, that contains hair cells. Rotation of the head causes a flow of fluid, which in turn causes displacement of the top portion of the hair cells that are embedded in the jelly-like cupula. Two other organs that are part of the vestibular system are the utricle and saccule. These are called the otolithic organs and are responsible for detecting linear acceleration, or movement in a straight line. The hair cells of the otolithic organs are blanketed with a jelly-like layer studded with tiny calcium stones called otoconia. When the head is tilted or the body position is changed with respect to gravity, the displacement of the stones causes the hair cells to bend.

The balance system works with the visual and skeletal systems (the muscles and joints and their sensors) to maintain orientation or balance. For example, visual signals are sent to the brain about the body's position in relation to its surroundings. These signals are processed by the brain, and compared to information from the vestibular, visual and the skeletal systems.

Disordered Balance


Problems with balance occur whenever there is a disruption in any of the vestibular, visual, proprioceptive or cognitive systems. Symptoms of a balance disorder may include dizziness, vertigo
Vertigo (medical)

Vertigo is a specific type of dizziness, a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is actually stationary with respect to the surroundings....
 (spinning), disequilibrium (off balance and falls), pre-syncope (light headedness). Abnormalities in balance function may indicate a wide range of pathologies from causes like low blood pressure to stroke or brain tumors.

Many different terms are often used to describe what is collectively known as dizziness. Common descriptions include words such as lightheaded, floating, woozy, giddy, confused, helpless or fuzzy. Vertigo, Disequilibrium and Pre-syncope are the terms in use by most doctors.

Vertigo
Vertigo (medical)

Vertigo is a specific type of dizziness, a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is actually stationary with respect to the surroundings....


Vertigo is a specific medical term used to describe the sensation of spinning or having the room spin about you. Most people find vertigo very disturbing and report associated nausea and vomiting.

Disequilibrium
Equilibrioception

Equilibrioception or sense of balance is one of the physiology senses. It helps prevent humans and animals from falling over when walking or standing still....


Disequilibrium is the sensation of being off balance, and is most often characterized by frequent falls in a specific direction. This condition is not often associated with nausea or vomiting.

Pre-syncope

Pre-syncope is most often described as lightheaded or feeling faint. Syncope, by contrast, is actually fainting.

Types of Balance Problems


Related to the Ear

Causes of dizziness related to the ear are often characterized by vertigo (spinning) and nausea. Nystagmus
Nystagmus

Pathologic nystagmus is a form of involuntary eye movement. It is characterized by alternating smooth pursuit in one direction and saccadic movement in the other direction....
 (flickering of the eye, related to the VOR) is often seen in patients with an acute peripheral cause of dizziness.

  • Benign Paroxysmal Positional Vertigo
    Benign paroxysmal positional vertigo

    Benign paroxysmal positional vertigo or benign paroxysmal vertigo is a disorder caused by problems in the inner ear. Its symptoms are repeated episodes of positional vertigo, that is, of a spinning sensation caused by changes in head position....
     (BPPV) - The most common cause of vertigo. Typically described as a brief, intense sensation of spinning that occurs because of a specific change in the position of head. An individual may experience BPPV when rolling over to the left or right, upon getting out of bed in the morning, or when looking up for an object on a high shelf. The cause of BPPV is the presence of normal but misplaced crystals called otoconia. Otoconia are normally found in the utricle and saccule and are used to sense movement. When loose in the semicircular canals, they can distort the sense of movement, causing a mismatch between actual head movement and the information sent to the brain by the inner ear, this is interpreted as spinning.
  • Labyrinthitis
    Labyrinthitis

    Labyrinthitis is a balance disorder. It is an inflammatory process affecting the Labyrinth s that house the vestibular system of the inner ear....
     - An inner ear infection or inflammation causing both dizziness (vertigo) and hearing loss.
    • Vestibular neuronitis
      Vestibular neuronitis

      Vestibular Neuronitis, also called Vestibular neuritis, can be a paroxysmal, single attack of Vertigo , a series of attacks, or a persistent condition which diminishes over two weeks....
       - an infection of the vestibular nerve, generally viral, causing vertigo
    • Cochlear neuronitis - an infection of the cochlear nerve, generally viral, causing sudden deafness but no vertigo
  • Trauma - Injury to the skull may cause either a fracture or a concussion to the organ of balance. In either case an acute head injury will often result in dizziness and a sudden loss of vestibular function.
  • Ménière's disease
    Ménière's disease

    M?ni?re's disease is a disorder of the inner ear that can affect Hearing and balance. It is characterized by episodes of dizziness and tinnitus and progressive hearing loss, usually in one ear....
     - an inner ear fluid balance disorder that causes lasting episodes of vertigo, fluctuating hearing loss, tinnitus
    Tinnitus

    Tinnitus is the perception of sound within the human ear in the absence of corresponding external sound.Tinnitus can be perceived in one or both ears or in the head....
     (a ringing or roaring in the ears), and the sensation of fullness in the ear. The cause of Ménière's disease is unknown.
  • Perilymph fistula
    Perilymph fistula

    A labyrinthine fistula is leakage of inner ear fluid into the air filled middle ear.It is a cause of balance disorders and can be a complication of a stapedectomy....
     - a leakage of inner ear fluid from the inner ear. It can occur after head injury, surgery, physical exertion or without a known cause.
  • Superior canal dehiscence syndrome
    Superior canal dehiscence syndrome

    Superior canal dehiscence syndrome is a rare medical condition of the inner ear, first described in 1998 by of Johns Hopkins University Hospital, Baltimore, USA,...
     - a balance and hearing disorder caused by a gap in the temporal bone, leading to the dysfunction of the superior canal.
  • Bilateral vestibulopathy
    Bilateral Vestibulopathy

    Bilateral Vestibulopathy results as the culmination of damage done to both inner ears. Bilateral Vestibulopathy causes problems in vision, hearing and motor coordination....
     - a condition caused by loss of inner ear
    Inner ear

    The inner ear is the labyrinth , a system of passages comprising two main functional parts:* the organ of hearing, or cochlea* and the vestibular apparatus, the organ of balance that consists of three semicircular canals and the Vestibule of the ear....
     balance function.


Related to the Brain

Brain related causes are less commonly associated with isolated vertigo and nystagmus but can still produce signs and symptoms which mimic peripheral causes. Disequilibrium is often a prominent feature.

  • Degenerative: Age related decline in balance function
  • Infectious: Meningitis
    Meningitis

    Meningitis is a medical condition caused by inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges....
    , encephalitis
    Encephalitis

    Not to be confused with syphilis, although that can cause encephalitis as well.Encephalitis is an Acute inflammation of the brain.Encephalitis with meningitis is known as meningoencephalitis....
    , epidural abscess, Syphilis
    Syphilis

    Syphilis is a sexually transmitted disease caused by the spirochete bacterium Treponema pallidum subspecies pallidum. The route of transmission of syphilis is almost always through sexual contact, although there are examples of congenital syphilis via transmission from mother to child in utero....
  • Circulatory: Cerebral or Cerebellar ischemia
    Ischemia

    In medicine, ischemia is a restriction in blood supply, generally due to factors in the blood vessels, with resultant damage or dysfunction of tissue....
     or hypoperfusion, Stroke
    Stroke

    A stroke is the rapidly developing loss of brain function due to a disturbance in the blood supply to the brain. According to the National Stroke Association, a "stroke" occurs when a blood clot blocks and artery or a blood vessel breaks, interrupting blood flow to an area of the brain....
    , Lateral medullary syndrome
    Lateral medullary syndrome

    Lateral medullary syndrome is a disease in which the patient has difficulty with swallowing or speaking or both owing to one or more patches of dead tissue caused by interrupted blood supply to parts of the brain....
     (Wallenberg's syndrome)
  • Autoimmune: Cogan syndrome
    Cogan syndrome

    Cogan syndrome is a rare disorder characterized by recurrent inflammation of the front of the eye and often fever, fatigue, and weight loss, episodes of dizziness, and hearing loss....
  • Structural: Arnold-Chiari malformation
    Arnold-Chiari malformation

    Arnold-Chiari malformation is a malformation of the brain. It consists of a downward displacement of the cerebellar tonsils and the Medulla oblongata through the foramen magnum, sometimes causing hydrocephalus as a result of obstruction of CSF outflow....
    , Hydrocephalus
  • Systemic: Multiple Sclerosis
    Multiple sclerosis

    Multiple sclerosis is an autoimmune disease in which the immune system attacks the central nervous system, leading to demyelinating disease. Disease onset usually occurs in young adults, and it is more common in females....
    , Parkinsons
  • CNS or Posterior Neoplasms: Benign or Malignant


  • Other - There are a host of other causes of dizziness not related to the ear.
    • Mal de Debarquement is rare disorder of imbalance caused by being on board a ship. Patients suffering from this condition feel sea sick even when they get off the ship.
    • Motion Sickness - a conflict between the input from the various systems involved in balance causes an unpleasant sensation. For this reason looking out the window of a moving car is much more pleasant than looking inside the vehicle.
    • Toxins, drugs, medications


Symptoms

When balance is impaired, an individual has difficulty maintaining orientation. For example, an individual may experience the "room spinning" and may not be able to walk without staggering, or may not even be able to stand. Some of the symptoms a person with a balance disorder may experience are:

  • A sensation of dizziness or vertigo.
  • Falling or a feeling of falling.
  • Lightheadedness or feeling woozy.
  • Problems reading and difficulty seeing.
  • Disorientation.


Some individuals may also experience nausea
Nausea

Nausea is the sensation of unease and discomfort in the stomach with an urge to vomit....
 and vomiting, diarrhea
Diarrhea

In medicine, diarrhea, also spelled diarrhoea , is characterized by frequent loose or liquid bowel movements. The spelling of "diarrhea" is an appropriation of the Greek "diarrhoia" meaning "a flowing through." ....
, faintness, changes in heart rate and blood pressure
Blood pressure

Blood pressure is the pressure exerted by circulating blood on the walls of blood vessels, and constitutes one of the principal vital signs. The pressure of the circulating blood decreases as it moves away from the heart through artery and capillary, and toward the heart through veins....
, fear, anxiety, or panic. Some reactions to the symptoms are fatigue, depression, and decreased concentration. The symptoms may appear and disappear over short time periods or may last for a longer period of time.

Cognitive dysfunction (disorientation) is often seen with vestibular disorders. Cognitive deficits are not just spatial in nature, but also include non-spatial functions such as object recognition memory. Vestibular dysfunction has been shown to adversely affect attentional processes and increased attentional demands can worsen the postural sway associated with vestibular disorders. Recent MRI studies also show that humans with bilateral vestibular damage undergo atrophy
Atrophy

Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include poor nourishment, poor circulatory system, loss of hormone support, loss of nerve supply to the target Organ , disuse or lack of exercise or disease intrinsic to the tissue itself....
 of the hippocampus
Hippocampus

The hippocampus is a brain structure located inside the medial temporal lobe of the cerebral cortex, and therefore is part of the telencephalon ....
 which correlates with their degree of impairment on spatial memory tasks.

Diagnosis

Diagnosis of a balance disorder is complicated because there are many kinds of balance disorders and because other medical conditions — including ear infections, blood pressure changes, and some vision problems — and some medications may contribute to a balance disorder. A person experiencing dizziness should see a physician for an evaluation. Once diagnosed with, or cleared of a medical disorder, a physiotherapist can assess balance in detail.

The primary physician may request the opinion of an otolaryngologist to help evaluate a balance problem. An otolaryngologist is a physician/surgeon who specializes in diseases and disorders of the ear, nose, throat, head, and neck, sometimes with expertise in balance disorders. He or she will usually obtain a detailed medical history and perform a physical examination to start to sort out possible causes of the balance disorder. The physician may require tests and make additional referrals to assess the cause and extent of the disruption of balance. The kinds of tests needed will vary based on the patient's symptoms and health status. Because there are so many variables, not all patients will require every test.

Diagnostic Testing

Tests of vestibular system
Vestibular system

The vestibular system, which contributes to our balance and our sense of spatial orientation, is the sensory system that provides the dominant input about movement and equilibrioception....
 (balance) function include electronystagmography
Electronystagmography

Electronystagmography is a diagnostic test to record involuntary movements of the eye caused by a condition known as nystagmus. It can also be used to diagnose the cause of vertigo , dizziness or balance disorder dysfunction by testing the vestibular system....
 (ENG), Videonystagmograph (VNG), rotation tests, Computerized Dynamic Posturography
Posturography

Posturography is a general term that covers all the techniques used to quantify postural control in upright stance in either static or dynamic conditions....
 (CDP), and Caloric reflex test
Caloric reflex test

In medicine, the caloric reflex test is a test of the vestibulo-ocular reflex that involves irrigating cold or warm water or air into the external auditory canal....
.

Tests of auditory system
Auditory system

The auditory system is the sensory system for the sense of hearing ....
 (hearing) function include pure-tone audiometry, speech audiometry, acoustic-reflex, electrocochleography (ECoG), otoacoustic emissions (OAE), and auditory brainstem response test
Auditory Brainstem Response

Auditory brainstem response is an electrical signal evoked from the brainstem of a human or other mammal by the presentation of a sound such as a click....
 (ABR; also known as BER, BSER, or BAER).

Other diagnostic tests include magnetic resonance imaging
Magnetic resonance imaging

GaneshMagnetic resonance imaging , or nuclear magnetic resonance imaging , is primarily a medical imaging technique most commonly used in radiology to visualize the structure and function of the body....
 (MRI) and computerized axial tomography (CAT, or CT).

Treatment

There are various options for treating balance disorders. One option includes treatment for a disease or disorder that may be contributing to the balance problem, such as ear infection, stroke, or multiple sclerosis
Multiple sclerosis

Multiple sclerosis is an autoimmune disease in which the immune system attacks the central nervous system, leading to demyelinating disease. Disease onset usually occurs in young adults, and it is more common in females....
. Individual treatment will vary and will be based upon symptoms, medical history, general health, examination by a physician, and the results of medical tests. Most types of balance disorders will require balance training, prescribed by a physiotherapist.

BPPV

Benign Paroxysmal Positional Vertigo
Benign paroxysmal positional vertigo

Benign paroxysmal positional vertigo or benign paroxysmal vertigo is a disorder caused by problems in the inner ear. Its symptoms are repeated episodes of positional vertigo, that is, of a spinning sensation caused by changes in head position....
 (BPPV) is caused by misplaced crystals within the ear. Treatment, simply put, involves moving these crystals out of areas which cause vertigo and into areas where they do not. A number of exercises have been developed to shift these crystals. The following article explains with diagrams how these exercises can be performed at the office or at home with some help: The success of these exercises depends on them being performed correctly.

The two exercises explained in the above article are:
  • The Brandt-Daroff Exercises, which can be done at home and have a very high success rate but are unpleasant and time consuming to perform.
  • The Epley's exercises are often performed by a doctor but can be performed at home. Various devices are available for home BPPV treatment
    DizzyFIX

    The DizzyFIX is an FDA cleared home medical device available to assist in the treatment of Benign Paroxysmal Positional Vertigo and its associated vertigo....
    .


Ménière's disease

  • Diet: Dietary changes such as reducing intake of sodium (salt) may help. For some people, reducing alcohol
    Alcohol

    In chemistry, an alcohol is any organic compound in which a hydroxyl Functional group is bound to a carbon atom of an alkyl or substituted alkyl group....
    , caffeine
    Caffeine

    Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a psychoactive stimulant drug and a mild diuretic. Caffeine was discovered by a German chemist, Friedrich Ferdinand Runge, in 1819....
    , and/or avoiding nicotine
    Nicotine

    Nicotine is an alkaloid found in the nightshade family of plants which constitutes approximately 0.6?3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves....
     may be helpful. Stress has also been shown to make the symptoms associated with ménière's worse
  • Drugs:
    • Beta-histine (Serc) is available in some countries and is thought to reduce the frequency of symptoms
    • Diuretics such as hydrochlorohyiazide (Diazide)have also been shown to reduce the frequency of symptoms
    • Aminoglycoside antibiotics (gentamicin) can used to treat Ménière's disease. Systemic streptomycin (given by injection) and topical gentamicin (given directly to the inner ear) are useful for their ability to affect the hair cells of the balance system. Gentamicin also can affect the hair cells of the cochlea, though, and cause hearing loss in about 10% of patients. In cases that do not respond to medical management, surgery may be indicated.
  • Surgery for meniere's disease is a last resort
    • Vestibular neuronectomy can cure Meniere's disease but is very involved surgery and not widely available. It involves drilling into the skull and cutting the balance nerve just as it is about to enter the brain.
    • Labyrinthectomy (surgical removal of the whole balance organ)is more widely available as a treatment but causes total deafness in the affected ear.


Labyrinthitis

Treatment includes balance retraining exercises (vestibular rehabilitation). The exercises include movements of the head and body specifically developed for the patient. This form of therapy is thought to promote compensation for the disorder. Vestibular retraining programs are administered by professionals with knowledge and understanding of the vestibular system and its relationship with other systems in the body.

Medication

Sedative
Sedative

A sedative is a substance that induces sedation by reducing irritability or excitement.At higher doses it may result in slurred speech, staggering gait , poor judgment, and slow, uncertain reflexes....
 drugs are often prescribed for vertigo and dizziness, but these usually treat the symptoms rather than the underlying cause. Lorazepam (Ativan) is often used and is a sedative which has no effect on the disease process rather helps patients cope with the sensation.

Anti-nauseants, like those prescribed for motion sickness, are also often prescribed but do not effect the prognosis of the disorder.

Specifically for meniere's disease a medication called Serc (Beta-histine) is available. There is some evidence to support it is effective to reduce the frequency of attacks. Also Diuretics, like Diazide (HCTZ/triamterene), are effective in many patients. Finally, ototoxic medications delivered either systemically or through the eardrum can eliminate the vertigo associated with Meniere's in many cases, although there is about a 10% risk of further hearing loss when using ototoxic medications.

Treatment is specific for underlying disorder of balance disorder:

  • anticholinergics
  • antihistamines
  • benzodiazepines
  • calcium channel antagonists
    Calcium channel blocker

    Calcium channel blockers are a class of medication and natural substances which disrupt the conduction of calcium channels.It has effects on many excitable cells of the body, such as cardiac muscle, i.e....
    , specifically Verapamil
    Verapamil

    Verapamil is an L-type calcium channel blocker of the phenylalkylamine class. It has been used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and most recently, cluster headaches....
     and Nimodipine
    Nimodipine

    Nimodipine is a dihydropyridine calcium channel blocker originally developed for the treatment of arterial hypertension. It is not frequently used for this indication, but has shown good results in preventing a major complication of subarachnoid hemorrhage termed vasospasm; this is now the main use of nimodipine....
  • GABA modulators, specifically gabapentin
    Gabapentin

    Gabapentin is a Gamma-aminobutyric_acid analogue. It was originally developed for the treatment of epilepsy, and currently, gabapentin is widely used to relieve pain, especially neuropathic pain....
     and baclofen
    Baclofen

    Baclofen is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.It is an agonist specific to mammalian but not fruit fly GABA B receptors....
  • Neurotransmitter reuptake inhibitors such as SSRI's, SNRI's
    Serotonin-norepinephrine reuptake inhibitor

    Serotonin-norepinephrine reuptake inhibitors are a class of antidepressant used in the treatment of major depressive disorder and other mood disorders....
     and Tricyclics


Research

Scientists at the National Institute on Deafness and Other Communication Disorders (NIDCD) are working to understand the various balance disorders and the complex interactions between the labyrinth, other balance-sensing organs, and the brain. NIDCD scientists are studying eye movement to understand the changes that occur in aging, disease, and injury, as well as collecting data about eye movement and posture to improve diagnosis and treatment of balance disorders. They are also studying the effectiveness of certain exercises as a treatment option.

Other projects supported by the NIDCD include studies of the genes essential to normal development and function in the vestibular system. NIDCD scientists are also studying inherited syndromes of the brain that affect balance and coordination.

The NIDCD supports research to develop new tests and refine current tests of balance and vestibular function. For example, NIDCD scientists have developed computer-controlled systems to measure eye movement and body position by stimulating specific parts of the vestibular and nervous systems. Other tests to determine disability, as well as new physical rehabilitation strategies, are under investigation in clinical and research settings.

Scientists at the NIDCD hope that new data will help to develop strategies to prevent injury from falls, a common occurrence among people with balance disorders, particularly as they grow older.

External links



Source


This article is adapted from the public domain
Public domain

File:PD-icon.svgThe public domain is a range of abstract materials?commonly referred to as intellectual property?which are not owned or controlled by anyone....
 article at http://www.nidcd.nih.gov/health/balance/balance_disorders.asp