Bala S. Manian
Encyclopedia
Bala S. Manian is an India
India
India , officially the Republic of India , is a country in South Asia. It is the seventh-largest country by geographical area, the second-most populous country with over 1.2 billion people, and the most populous democracy in the world...

n-born Silicon Valley
Silicon Valley
Silicon Valley is a term which refers to the southern part of the San Francisco Bay Area in Northern California in the United States. The region is home to many of the world's largest technology corporations...

 entrepreneur
Entrepreneur
An entrepreneur is an owner or manager of a business enterprise who makes money through risk and initiative.The term was originally a loanword from French and was first defined by the Irish-French economist Richard Cantillon. Entrepreneur in English is a term applied to a person who is willing to...

 who has started a string of medical technology companies such as ReaMetrix, Digital Optics and Quantum Dot Corporation. Some of the resulting technologies have also had applications in the film industry, earning Manian an Academy Award certificate for technical achievement.

Early life

Bala Manian was born in Chennai
Chennai
Chennai , formerly known as Madras or Madarasapatinam , is the capital city of the Indian state of Tamil Nadu, located on the Coromandel Coast off the Bay of Bengal. Chennai is the fourth most populous metropolitan area and the sixth most populous city in India...

 (formerly Madras) India in 1944. He lost an eye in a childhood accident at age three and has seven siblings. His elder brother N. Vaghul has been chairman of ICICI Bank
ICICI Bank
ICICI Bank Ltd. is India's second largest financial services company headquartered in Mumbai, India. It offers a wide range of banking products and financial services to corporate and retail customers through a variety of delivery channels and through its specialised subsidiaries in the areas of...

. Manian earned a B.Sc. in physics
Physics
Physics is a natural science that involves the study of matter and its motion through spacetime, along with related concepts such as energy and force. More broadly, it is the general analysis of nature, conducted in order to understand how the universe behaves.Physics is one of the oldest academic...

 from Loyola College, Madras
Loyola College, Chennai
Loyola College is a Jesuit institution in Chennai, India. The college admits undergraduates and post-graduates and offers degrees in the liberal arts, sciences and commerce. It is an autonomous institution affiliated with the University of Madras.-History:...

 and a postgraduate level diploma
Diploma
A diploma is a certificate or deed issued by an educational institution, such as a university, that testifies that the recipient has successfully completed a particular course of study or confers an academic degree. In countries such as the United Kingdom and Australia, the word diploma refers to...

 in instrumentation from the Madras Institute of Technology at Madras
Madras Institute of Technology
The Madras Institute of Technology is an engineering institute located in Chromepet, Chennai , India. It is one of the four autonomous constituent colleges of Anna University. It was started in 1949 by Mr. C. Rajam as the first self-financing engineering institute in the country, and later it...

 before earning a Masters
Master's degree
A master's is an academic degree granted to individuals who have undergone study demonstrating a mastery or high-order overview of a specific field of study or area of professional practice...

 in optics at the University of Rochester
University of Rochester
The University of Rochester is a private, nonsectarian, research university in Rochester, New York, United States. The university grants undergraduate and graduate degrees, including doctoral and professional degrees. The university has six schools and various interdisciplinary programs.The...

. He then earned a Ph.D.
Ph.D.
A Ph.D. is a Doctor of Philosophy, an academic degree.Ph.D. may also refer to:* Ph.D. , a 1980s British group*Piled Higher and Deeper, a web comic strip*PhD: Phantasy Degree, a Korean comic series* PhD Docbook renderer, an XML renderer...

 from Purdue in 1971, conducting research in the Applied Optics Laboratory of the College of Engineering. From 1971 until 1974, Manian held a position as a senior research associate and assistant professor at the University of Rochester's Institute of Optics.

Career

As a consultant for various companies, he helped develop the first compact "under the counter" barcode laser scanner
Barcode reader
A barcode reader is an electronic device for reading printed barcodes. Like a flatbed scanner, it consists of a light source, a lens and a light sensor translating optical impulses into electrical ones...

 for supermarkets, several laser scanner-based stereo mapping instruments at the Defense Mapping Agency and image quality control instrumentation for photo reconnaissance systems. He also consulted on computer vision
Computer vision
Computer vision is a field that includes methods for acquiring, processing, analysing, and understanding images and, in general, high-dimensional data from the real world in order to produce numerical or symbolic information, e.g., in the forms of decisions...

 for on-line quality control
Quality control
Quality control, or QC for short, is a process by which entities review the quality of all factors involved in production. This approach places an emphasis on three aspects:...

 at several companies including Ford, IBM
IBM
International Business Machines Corporation or IBM is an American multinational technology and consulting corporation headquartered in Armonk, New York, United States. IBM manufactures and sells computer hardware and software, and it offers infrastructure, hosting and consulting services in areas...

, Corning, Kodak, and the Union Pacific Railroad
Union Pacific Railroad
The Union Pacific Railroad , headquartered in Omaha, Nebraska, is the largest railroad network in the United States. James R. Young is president, CEO and Chairman....

.

Manian then founded various other companies Digital Optics Corporation, an optical instrumentation and systems development company, which developed the first three-color laser, film reader/writer system. These techniques allowed filmmakers to insert or merge special effects into movies using computerized digital imaging. Working with David DiFrancesco and Tom Noggle, he created a technology that was transferred in 1983 to Industrial Light and Magic
Industrial Light and Magic
Industrial Light & Magic is an Academy Award-winning motion picture visual effects company that was founded in May 1975 by George Lucas and is owned by Lucasfilm. Lucas created the company when he discovered that the special effects department at 20th Century Fox was shut down after he was given...

,. It has been used in the production of numerous movies including "Indiana Jones and the Last Crusade
Indiana Jones and the Last Crusade
Indiana Jones and the Last Crusade is a 1989 American adventure film directed by Steven Spielberg, from a story co-written by executive producer George Lucas. It is the third film in the Indiana Jones franchise. Harrison Ford reprises the title role and Sean Connery plays Indiana's father, Henry...

" and "Return of the Jedi." In February 1999, Manian was awarded an Academy of Motion Picture Arts and Sciences
Academy of Motion Picture Arts and Sciences
The Academy of Motion Picture Arts and Sciences is a professional honorary organization dedicated to the advancement of the arts and sciences of motion pictures...

 Technical Award for this advance in technology. The same technology was then further developed to write the CAT scan and MRI images used in medical diagnosis
Medical diagnosis
Medical diagnosis refers both to the process of attempting to determine or identify a possible disease or disorder , and to the opinion reached by this process...

 directly onto film. This required a special film developed by Kodak for optimum results. Manian sold Digital Optics in 1984 for $7.5 million to the Matrix Corporation.

Manian remained as Chief Technical Officer
Chief technical officer
A chief technology officer is an executive-level position in a company or other entity whose occupant is focused on scientific and technological issues within an organization....

 for Digital Optics through 1985 and thenacted as an investor and independent consultant to several venture capital
Venture capital
Venture capital is financial capital provided to early-stage, high-potential, high risk, growth startup companies. The venture capital fund makes money by owning equity in the companies it invests in, which usually have a novel technology or business model in high technology industries, such as...

 firms before becoming the founder and Chief Technical Officer for two startups, Molecular Dynamics
Molecular dynamics
Molecular dynamics is a computer simulation of physical movements of atoms and molecules. The atoms and molecules are allowed to interact for a period of time, giving a view of the motion of the atoms...

 and Lumisys, a company dealing in laser-based x-ray
X-ray
X-radiation is a form of electromagnetic radiation. X-rays have a wavelength in the range of 0.01 to 10 nanometers, corresponding to frequencies in the range 30 petahertz to 30 exahertz and energies in the range 120 eV to 120 keV. They are shorter in wavelength than UV rays and longer than gamma...

 film digitizers.

He then founded Biometric Imaging and became the Chief Technical Officer. The company has developed technology that allows doctors to examine the blood cells of seriously ill patients and determine the nature and extent of their disease. It also gives pharmaceutical companies the ability to perform cell function analyses in the discovery and development of pharmaceutical drugs. Manian co-founded the company Surromed and Quantum Dot Corporation in 1998. Quantum Dot Corporation (QDC) developed and sold novel solutions to accelerate the discovery and development of functionally validated novel drug targets at the cellular level. QDC's products and services employ quantum dot (Qdot) particles. Bala Manian founded ReaMetrix in May 2003. and serves as a science and business advisor for a number of entrepreneurial companies (Galileo Labs, Biocon India, ICICI Knowledge Park and APIDC -VC). Currently, he is also an advisor to the startup TeliportMe.

External links

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