Alvaro Pascual-Leone
Encyclopedia
Alvaro Pascual-Leone is a country and member state of the European Union located in southwestern Europe on the Iberian Peninsula...

) is a Professor of Neurology
Neurology
Neurology is a medical specialty dealing with disorders of the nervous system. Specifically, it deals with the diagnosis and treatment of all categories of disease involving the central, peripheral, and autonomic nervous systems, including their coverings, blood vessels, and all effector tissue,...

 at Harvard Medical School
Harvard Medical School
Harvard Medical School is the graduate medical school of Harvard University. It is located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts....

, with which he has been affiliated since 1997. He is the Director of the Berenson-Allen Center for Noninvasive Brain Stimulation and Program Director of the Harvard-Thorndike Clinical Research Center of the Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center in Boston, Massachusetts is a major flagship teaching hospital of Harvard Medical School. It was formed out of the 1996 merger of Beth Israel Hospital and New England Deaconess Hospital...

 in Boston
Boston
Boston is the capital of and largest city in Massachusetts, and is one of the oldest cities in the United States. The largest city in New England, Boston is regarded as the unofficial "Capital of New England" for its economic and cultural impact on the entire New England region. The city proper had...

.

Dr. Pascual-Leone obtained an M.D.
Doctor of Medicine
Doctor of Medicine is a doctoral degree for physicians. The degree is granted by medical schools...

 and a Ph.D.
Doctor of Philosophy
Doctor of Philosophy, abbreviated as Ph.D., PhD, D.Phil., or DPhil , in English-speaking countries, is a postgraduate academic degree awarded by universities...

 in Neurophysiology
Neurophysiology
Neurophysiology is a part of physiology. Neurophysiology is the study of nervous system function...

 from the Faculty of Medicine
Medical school
A medical school is a tertiary educational institution—or part of such an institution—that teaches medicine. Degree programs offered at medical schools often include Doctor of Osteopathic Medicine, Bachelor/Doctor of Medicine, Doctor of Philosophy, master's degree, or other post-secondary...

 of Albert Ludwigs University in Germany
Germany
Germany , officially the Federal Republic of Germany , is a federal parliamentary republic in Europe. The country consists of 16 states while the capital and largest city is Berlin. Germany covers an area of 357,021 km2 and has a largely temperate seasonal climate...

. He also trained at the University of Minnesota
University of Minnesota
The University of Minnesota, Twin Cities is a public research university located in Minneapolis and St. Paul, Minnesota, United States. It is the oldest and largest part of the University of Minnesota system and has the fourth-largest main campus student body in the United States, with 52,557...

 and the US National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...

.

He has authored over 350 scientific papers and is the recipient of several international honors and awards, including the Ramon y Cajal Award in Neuroscience (Spain), the Norman Geschwind Prize in Behavioral Neurology from the American Academy of Neurology, the Friedrich Wilhelm Bessel Research Award from The Alexander von Humboldt Foundation (Germany), and the Jean Signoret Prize from the Ipsen Foundation (France). In 2000, he won the Daniel D. Federman Outstanding Clinical Educator Award. He is a member of the Spanish Royal Academy of Pharmacy.

Pascual-Leone is a world leader in the development of transcranial magnetic stimulation
Transcranial magnetic stimulation
Transcranial magnetic stimulation is a noninvasive method to cause depolarization or hyperpolarization in the neurons of the brain...

 for application in cognitive neuroscience and for therapeutic applications in neurology, psychiatry and neurorehabilitation. Pascual-Leone's research aims at understanding the mechanisms that control brain plasticity across the lifespan to be able to modify them for the subject’s optimal behavioral outcome. Pascual-Leone combines various brain imaging and brain stimulation methodologies to establish a causal relationship and a precise chronometry between regional brain activation and behavior, and uses noninvasive brain stimulation techniques to modulate brain plasticity, suppressing some changes and enhancing others, to gain a clinical benefit and behavioral advantage for a given individual. Such non-invasive approaches can lead to clinically relevant therapeutic effects in neuropsychiatry and neurorehabilitation, and serve as proof-of-principle prior to more invasive neuromodulatory interventions.

Pascual-Leone lives in Wayland
Wayland, Massachusetts
Wayland is a town in Middlesex County, Massachusetts, United States. The population was 12,994 at the 2010 census.For geographic and demographic information on Cochituate, which is part of Wayland, please see the article Cochituate, Massachusetts.-History:...

, Massachusetts
Massachusetts
The Commonwealth of Massachusetts is a state in the New England region of the northeastern United States of America. It is bordered by Rhode Island and Connecticut to the south, New York to the west, and Vermont and New Hampshire to the north; at its east lies the Atlantic Ocean. As of the 2010...

 with his wife Elizabeth and their three children.

External links

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