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Aaron Ciechanover

 

 
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Aaron Ciechanover
 
 
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Aaron Ciechanover (???? ?'?????) (born October 1, 1947) is an Israel
Israel

Israel officially the State of Israel , is a country in the Middle East located on the eastern shore of the Mediterranean Sea. It borders Lebanon in the north, Syria in the northeast, Jordan in the east, and Egypt on the southwest, and contains geographically diverse features within its relatively small area....
i biologist
Biology

Biology is a branch of the natural sciences concerned with the study of living organisms and their interaction with each other and their environment ....
, and Nobel laureate in Chemistry
Chemistry

Chemistry is the science concerned with the composition, structure, and properties of matter, as well as the changes it undergoes during chemical reactions....
 for his discovery with Avram Hershko
Avram Hershko

Avram Hershko is an Israeli biology and Nobel laureate in Chemistry for his discovery with Aaron Ciechanover and Irwin Rose, of ubiquitin-mediated protein degradation....
 and Irwin Rose
Irwin Rose

Irwin A. Rose is an American biology. Along with Aaron Ciechanover and Avram Hershko, he was awarded the 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation....
, of ubiquitin
Ubiquitin

Ubiquitin is a highly-conserved regulatory protein that is :wiktionary:ubiquitous expressed in eukaryotes. Ubiquitination refers to the post-translational modification of a protein by the covalent attachment of one or more ubiquitin monomers....
-mediated protein degradation. He also received in 2000 the Albert Lasker Award for Basic Medical Research
Albert Lasker Award for Basic Medical Research

The Albert Lasker Award for Basic Medical Research is one of the Lasker Award awarded by the Lasker Foundation for the understanding, diagnosis, prevention, treatment, and cure of disease....
 and the Israel Prize
Israel Prize

The Israel Prize is an award handed out by the State of Israel. It is presented annually, on Yom Ha'atzma'ut, in a state ceremony in Jerusalem, in the presence of the President of Israel, the Prime Minister of Israel, the Knesset chairperson, and the Supreme Court of Israel president....
 for Biological Research in 2003.

in Haifa
Haifa

Haifa is the largest city in North District Israel, and the List of Israeli cities in the country, with a population of over 264,900. Haifa has a mixed population of Jews and Arabs....
, British Mandate of Palestine, Ciechanover received his Master of Science degree in 1971 and his M.D. in 1974 from the Hadassah Medical School of the Hebrew University in Jerusalem
Jerusalem

Jerusalem is the capital of Israel and its List of Israeli cities in both population and area, with a population of 747,600 residents over an area of if Positions on Jerusalem East Jerusalem is included....
.






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Aaron Ciechanover (???? ?'?????) (born October 1, 1947) is an Israel
Israel

Israel officially the State of Israel , is a country in the Middle East located on the eastern shore of the Mediterranean Sea. It borders Lebanon in the north, Syria in the northeast, Jordan in the east, and Egypt on the southwest, and contains geographically diverse features within its relatively small area....
i biologist
Biology

Biology is a branch of the natural sciences concerned with the study of living organisms and their interaction with each other and their environment ....
, and Nobel laureate in Chemistry
Chemistry

Chemistry is the science concerned with the composition, structure, and properties of matter, as well as the changes it undergoes during chemical reactions....
 for his discovery with Avram Hershko
Avram Hershko

Avram Hershko is an Israeli biology and Nobel laureate in Chemistry for his discovery with Aaron Ciechanover and Irwin Rose, of ubiquitin-mediated protein degradation....
 and Irwin Rose
Irwin Rose

Irwin A. Rose is an American biology. Along with Aaron Ciechanover and Avram Hershko, he was awarded the 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation....
, of ubiquitin
Ubiquitin

Ubiquitin is a highly-conserved regulatory protein that is :wiktionary:ubiquitous expressed in eukaryotes. Ubiquitination refers to the post-translational modification of a protein by the covalent attachment of one or more ubiquitin monomers....
-mediated protein degradation. He also received in 2000 the Albert Lasker Award for Basic Medical Research
Albert Lasker Award for Basic Medical Research

The Albert Lasker Award for Basic Medical Research is one of the Lasker Award awarded by the Lasker Foundation for the understanding, diagnosis, prevention, treatment, and cure of disease....
 and the Israel Prize
Israel Prize

The Israel Prize is an award handed out by the State of Israel. It is presented annually, on Yom Ha'atzma'ut, in a state ceremony in Jerusalem, in the presence of the President of Israel, the Prime Minister of Israel, the Knesset chairperson, and the Supreme Court of Israel president....
 for Biological Research in 2003.

Biography

Born in Haifa
Haifa

Haifa is the largest city in North District Israel, and the List of Israeli cities in the country, with a population of over 264,900. Haifa has a mixed population of Jews and Arabs....
, British Mandate of Palestine, Ciechanover received his Master of Science degree in 1971 and his M.D. in 1974 from the Hadassah Medical School of the Hebrew University in Jerusalem
Jerusalem

Jerusalem is the capital of Israel and its List of Israeli cities in both population and area, with a population of 747,600 residents over an area of if Positions on Jerusalem East Jerusalem is included....
. He received his doctorate in biochemistry in 1982 from the Technion (the Israel Institute of Technology), in Haifa. He is currently a Technion Distinguished Research Professor in the Ruth and Bruce Rappaport Faculty of Medicine
Ruth and Bruce Rappaport Faculty of Medicine

Ruth and Bruce Rappaport Faculty of Medicine is a medical school which is part of Technion - Israel Institute of Technology in Haifa, Israel. It was founded in 1969....
 and Research Institute at the Technion.

Ciechanover is a member of the Israel Academy of Sciences and Humanities
Israel Academy of Sciences and Humanities

The Israel Academy of Sciences and Humanities, based in Jerusalem, was set up in 1961 by the State of Israel to foster contact between scholars from the sciences and humanities in Israel, to advise the government on research projects of national importance, and to promote excellence....
, the Pontifical Academy of Sciences
Pontifical Academy of Sciences

The Pontifical Academy of Sciences was founded by the Roman Catholic Church in 1936 under its current name by Pope Pius XI and is placed under the protection of the reigning Supreme Pontiff ....
, and is a foreign associate of the United States National Academy of Sciences
United States National Academy of Sciences

The National Academy of Sciences is a corporation in the United States whose members serve pro bono as "advisers to the nation on science, engineering, and medicine."...
.

His family came to Palestine from Poland
Poland

Poland , officially the Republic of Poland , is a country in Central Europe. Poland is bordered by Germany to the west; the Czech Republic and Slovakia to the south; Ukraine, Belarus and Lithuania to the east; and the Baltic Sea and Kaliningrad Oblast, a Russian Enclave and exclave, to the north....
 before the Second World War.

Publications

  • Ciechanover, A., Hod, Y. and Hershko, A. (1978). A Heat-stable Polypeptide Component of an ATP-dependent Proteolytic System from Reticulocytes. Biochem. Biophys. Res. Commun. 81, 1100-1105.
  • Ciechanover, A., Heller, H., Elias, S., Haas, A.L. and Hershko, A. (1980). ATP-dependent Conjugation of Reticulocyte Proteins with the Polypeptide Required for Protein Degradation. Proc. Natl. Acad. Sci. USA 77, 1365-1368.
  • Hershko, A. and Ciechanover, A. (1982). Mechanisms of intracellular protein breakdown. Annu. Rev. Biochem. 51, 335-364.


External links

  • - A web article