Major intersections

Note: mileposts do not reflect actual mileage due to realignments.

County	Location	Mile	Destinations	Notes
Lake Lake County, Oregon Lake County is a county in the high desert south central region of the U.S. state of Oregon, so named for the many lakes found within its boundaries, including Lake Abert, Hart Lake Reservoir, and Goose Lake. While Lake is among Oregon's largest counties, it is sparsely populated with 7,895...	New Pine Creek New Pine Creek, Oregon New Pine Creek is an unincorporated community in Lake County, Oregon, United States. Although it is unincorporated, it has a post office with a ZIP code of 97635. New Pine Creek lies on U.S...	157.73	California state line
	Lakeview Lakeview, Oregon Lakeview is a city in Lake County, Oregon, United States. The population was 2,294 at the 2010 census. It is the county seat of Lake County. Although it is an incorporated city, the municipal government refers to the community as "The Town of Lakeview", and bills itself as "Tallest Town in Oregon"...	143.03		South end of OR 140 overlap
		138.34	, Winnemucca Winnemucca, Nevada -Demographics:As of the census of 2000, there were 7,174 people, 2,736 households, and 1,824 families residing in the city. The population density was 867.5 people per square mile . There were 3,280 housing units at an average density of 396.6 per square mile...	North end of OR 140 overlap
	Valley Falls Valley Falls, Oregon Valley Falls is an unincorporated community in Lake County, Oregon, United States. Valley Falls lies on U.S. Route 395 just south of its junction with Oregon Route 31 near Lake Abert....	120.57 90.02
Harney Harney County, Oregon -National protected areas:*Malheur National Forest *Malheur National Wildlife Refuge*Ochoco National Forest -Demographics:As of the census of 2000, there were 7,609 people, 3,036 households, and 2,094 families residing in the county. The population density was 1 people per square mile...	Riley Riley, Oregon Riley, Oregon is an unincorporated community in Harney County, Oregon, United States. The center of the community is at the crossroads of U.S. Highway 395 and U.S. Highway 20, milepost 104. Riley is about west of Burns, the seat of Harney County. The elevation of Riley is .Riley is farming and...	0.11 104.77		South end of US 20 overlap
	Burns Burns, Oregon Burns is a city in and the county seat of Harney County, Oregon, United States. As of the 2010 census the population was 2,806.-History:Burns was established in the early 1880s and incorporated upon Harney county's creation in 1889...	131.50	, Winnemucca Winnemucca, Nevada -Demographics:As of the census of 2000, there were 7,174 people, 2,736 households, and 1,824 families residing in the city. The population density was 867.5 people per square mile . There were 3,280 housing units at an average density of 396.6 per square mile...
		134.29 67.61		North end of US 20 overlap
Grant Grant County, Oregon Grant County is a county located in the U.S. state of Oregon. It is included in the 8 county definition of Eastern Oregon. In 2010, its population was 7,445. It is named for President Ulysses S. Grant, who served as an army officer in the Oregon Territory, and at the time of the county's creation...	Canyon City Canyon City, Oregon Canyon City is a city in Grant County, Oregon, United States. It is the county seat of Grant County, and is about a mile south of John Day on U.S. Highway 395. As of the 2010 census, the city had a total population of 703.-History:...	0.00 162.29		South end of US 26 overlap
	Mount Vernon Mount Vernon, Oregon Mount Vernon is a city in Grant County, Oregon, United States. The population was 595 at the 2000 census.-Geography:According to the United States Census Bureau, the city has a total area of , all of it land.-Demographics:...	154.03 120.51		North end of US 26 overlap
	Long Creek Long Creek, Oregon Long Creek is a city in Grant County, Oregon, United States. The population was 228 at the 2000 census. The city is named after John Long, a prominent miner who came to Grant County in 1862 during the Canyon City rush of that same year. Located in a high valley of the Blue Mountains, ranching has...	90.26
Umatilla Umatilla County, Oregon Umatilla County is a county located in the U.S. state of Oregon. It is included in the 8 county definition of Eastern Oregon. The county is named for the Umatilla River. In 2010, its population was 75,889...		49.57
	Nye Nye, Oregon Nye is an unincorporated community in Umatilla County, Oregon, United States. It is located about eight miles west of Pilot Rock, at the junction of U.S. Route 395 and Oregon Route 74....	23.65
	Pendleton Pendleton, Oregon Pendleton is a city in Umatilla County, Oregon, United States. Pendleton was named in 1868 by the county commissioners for George H. Pendleton, Democratic candidate for Vice-President in the 1864 presidential campaign. The population was 16,612 at the 2010 census...	1.57 209.17		Interchange; south end of I-84 overlap; south end of freeway
		207.47		South end of US 30 overlap
		202.87	Barnhart Road – Stage Gulch
		199.53	Yoakum Road – Stage Gulch
		198.54	Lorenzen Road, McClintock Road
		193.53	Echo Road – Echo Echo, Oregon Echo is a city in Umatilla County, Oregon, United States. The population was 650 at the 2000 census. It is part of the Pendleton–Hermiston Micropolitan Statistical Area.-History:... , Lexington Lexington, Oregon Lexington is a city in Morrow County, Oregon, United States. The population was 263 at the 2000 census. It is part of the Pendleton–Hermiston Micropolitan Statistical Area.-History:...	Former Lexington-Echo Highway
	Stanfield Stanfield, Oregon Stanfield is a city in Umatilla County, Oregon, United States. The population was 1,979 at the 2000 census. It is part of the Pendleton–Hermiston Micropolitan Statistical Area.-Geography:...	188.98 12.68		Interchange; north end of I-84 / US 30 overlap; north end of freeway
	Hermiston Hermiston, Oregon As of the census of 2010, there were 16,745 people, 4,964 households, and 3,360 families residing in the city. The population density was 2,035.4 people per square mile . There were 5,383 housing units at an average density of 832.9 per square mile...	4.83	, Walla Walla Walla Walla, Washington Walla Walla is the largest city in and the county seat of Walla Walla County, Washington, United States. The population was 31,731 at the 2010 census...
	Umatilla Umatilla, Oregon Umatilla is a city in Umatilla County, Oregon, United States. It is named for the Umatilla River, which enters the Columbia River on the side of the city. The river is named after the Umatilla Tribe. The city is located on the south side of the Columbia River, and is located on U.S...	0.04 184.87	– Walla Walla Walla Walla, Washington Walla Walla is the largest city in and the county seat of Walla Walla County, Washington, United States. The population was 31,731 at the 2010 census... , McNary Dam McNary Dam McNary Dam is a 1.4-mile long concrete gravity run-of-the-river dam which spans the Columbia River. It joins Umatilla County, Oregon with Benton County, Washington, 292 miles upriver from the mouth of the Columbia at Astoria, Oregon. It is operated by the U.S. Army Corps of Engineers' McNary...	South end of US 730 overlap
		184.40 0.79		Interchange; north end of US 730 overlap; south end of I-82 overlap
		0.00	Umatilla Bridge Umatilla Bridge The Umatilla Bridge is the collective name for a pair of bridges carrying Interstate 82/U.S. Route 395 across the Columbia River at the Washington State/Oregon border...  over the Columbia River Columbia River The Columbia River is the largest river in the Pacific Northwest region of North America. The river rises in the Rocky Mountains of British Columbia, Canada, flows northwest and then south into the U.S. state of Washington, then turns west to form most of the border between Washington and the state... (state line)