Small nucleolar RNA SNORD78
Encyclopedia
U78 belongs to the CD family of snoRNA
SnoRNA
Small nucleolar RNAs are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs...

s. It is predicted to guide 2'O-ribose methylation
Methylation
In the chemical sciences, methylation denotes the addition of a methyl group to a substrate or the substitution of an atom or group by a methyl group. Methylation is a form of alkylation with, to be specific, a methyl group, rather than a larger carbon chain, replacing a hydrogen atom...

 of the large 28S rRNA subunit at position G4593. The snoRNAs U44
Small nucleolar RNA SNORD44
snoRNA U44 is a non-coding RNA molecule which functions in the modification of other small nuclear RNAs . This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis...

, U47
Small nucleolar RNA SNORD47
SNORD47 is a non-coding RNA molecule which functions in the modification of other small nuclear RNAs . This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis...

, U74, U75
Small nucleolar RNA SNORD75
Small Nucleolar RNA SNORD75 is a non-coding RNA molecule which functions in the biogenesis of other small nuclear RNAs . This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis...

, U76, U77
Small nucleolar RNA SNORD77
U77 belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of large 28S rRNA subunit at position A1521. The C/D snoRNAs U44, U47, U74, U75, U76, U78, U79, U80 and U81 share the same host gene as U77 ....

, U79
Small nucleolar RNA SNORD79
snoRNA U79 is a non-coding RNA molecule which functions in the modification of other small nuclear RNAs . This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis...

, U80 and U81
Small nucleolar RNA SNORD81
U81 is a member of the C/D class of snoRNA which contain the C and D box motifs. U81 acts as a guanine methylation guide and is found in intron 11 of the gas5 gene in mammals....

, also of the C/D family, share the same host gene with U78 (protein non-coding).
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