Satellite Tobacco Mosaic Virus
Encyclopedia
The Satellite Tobacco Mosaic Virus or Tobacco mosaic satellivirus was first reported in Nicotiana glauca
Nicotiana glauca
Nicotiana glauca is a species of wild tobacco known by the common names tree tobacco and incorrectly also Mustard tree. Its leaves are attached to the stalk by petioles , and its leaves and stems are neither pubescent nor sticky like Nicotiana tabacum...

from southern California, U.S.A. by Valverde and Dodds. Its genome
Genome
In modern molecular biology and genetics, the genome is the entirety of an organism's hereditary information. It is encoded either in DNA or, for many types of virus, in RNA. The genome includes both the genes and the non-coding sequences of the DNA/RNA....

 consists of linear single-stranded RNA
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....

. (1986)

"Satellite Tobacco Mosaic Virus is a small, icosahedral plant virus which worsens the symptoms of infection
Infection
An infection is the colonization of a host organism by parasite species. Infecting parasites seek to use the host's resources to reproduce, often resulting in disease...

 by Tobacco Mosaic Virus
Tobacco mosaic virus
Tobacco mosaic virus is a positive-sense single stranded RNA virus that infects plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns on the leaves . TMV was the first virus to be discovered...

 (TMV). Satellite viruses are some of the smallest possible reproducing units in nature; they achieve this by relying on both the host cell and a host virus (in this case, TMV) for the machinery necessary for them to reproduce. The entire STMV particle consists of 60 identical copies of a single protein that make up the viral capsid (coating), and a 1063-nucleotide single-stranded RNA
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....

 genome
Genome
In modern molecular biology and genetics, the genome is the entirety of an organism's hereditary information. It is encoded either in DNA or, for many types of virus, in RNA. The genome includes both the genes and the non-coding sequences of the DNA/RNA....

 which codes for the capsid
Capsid
A capsid is the protein shell of a virus. It consists of several oligomeric structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The capsid encloses the genetic...

 and one other protein of unknown function."

"Klaus Schulten at the University of Illinois, Urbana, and his colleagues built a computer model of the satellite tobacco mosaic virus, a tiny spherical package of RNA. [...] Running on a machine at the National Center for Supercomputing Applications, Urbana, the program calculated how each of the million or so atoms in the virus and a surrounding drop of salt water was interacting with almost every other atom every femtosecond, or millionth of a billionth of a second. [...] The fleeting simulation, published in this month's Structure, reveals that although the virus
Virus
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...

 looks symmetrical it pulses in and out asymmetrically, as if it were breathing."
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