Richard W. Tsien
Encyclopedia
Richard Winyu Tsien is a renowned American
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 neurobiologist. Tsien is the George D. Smith Professor of Molecular and Cellular Physiology at Stanford University
Stanford University
The Leland Stanford Junior University, commonly referred to as Stanford University or Stanford, is a private research university on an campus located near Palo Alto, California. It is situated in the northwestern Santa Clara Valley on the San Francisco Peninsula, approximately northwest of San...

. On January 2012, Dr. Tsien will move to New York University Medical Center as the director of the Neuroscience Institute and the Druckenmiller Professor of Neuroscience.

Biography

Tsien was born in Tating, Kweichow, China
China
Chinese civilization may refer to:* China for more general discussion of the country.* Chinese culture* Greater China, the transnational community of ethnic Chinese.* History of China* Sinosphere, the area historically affected by Chinese culture...

 and is a descendant
Lineal descendant
A lineal descendant, in legal usage, refers to a blood relative in the direct line of descent. The children, grandchildren, great-grandchildren, etc...

 of the King of Wuyue
Wuyue
Kingdom of Wuyue , 907-978, was a small independent coastal kingdom founded during the Five Dynasties and Ten Kingdoms of Chinese history. It was ruled by the Qian family, which remains widespread in the kingdom's former territory.-Founding:...

 Tsien Liu
Qian Liu
Qian Liu , courtesy name Jumei , nickname Poliu , formally King Wusu of Wuyue with the temple name of Taizu , was founder and first king of the Kingdom of Wuyue during the Five Dynasties and Ten Kingdoms Period, ruling over roughly modern Zhejiang on the east coast of China.- Background :Qian...

. Soon after his birth, Tsien's family moved to the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

. Tsien received BS
Bachelor of Science
A Bachelor of Science is an undergraduate academic degree awarded for completed courses that generally last three to five years .-Australia:In Australia, the BSc is a 3 year degree, offered from 1st year on...

 in 1965 and MS
Master of Science
A Master of Science is a postgraduate academic master's degree awarded by universities in many countries. The degree is typically studied for in the sciences including the social sciences.-Brazil, Argentina and Uruguay:...

 in 1966 both in electrical engineering
Electrical engineering
Electrical engineering is a field of engineering that generally deals with the study and application of electricity, electronics and electromagnetism. The field first became an identifiable occupation in the late nineteenth century after commercialization of the electric telegraph and electrical...

 and both from the Massachusetts Institute of Technology
Massachusetts Institute of Technology
The Massachusetts Institute of Technology is a private research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing a total of 32 academic departments, with a strong emphasis on scientific and technological education and research.Founded in 1861 in...

. Tsien then won the Rhodes Scholarship
Rhodes Scholarship
The Rhodes Scholarship, named after Cecil Rhodes, is an international postgraduate award for study at the University of Oxford. It was the first large-scale programme of international scholarships, and is widely considered the "world's most prestigious scholarship" by many public sources such as...

 and went to studied in UK at the University of Oxford
University of Oxford
The University of Oxford is a university located in Oxford, United Kingdom. It is the second-oldest surviving university in the world and the oldest in the English-speaking world. Although its exact date of foundation is unclear, there is evidence of teaching as far back as 1096...

 from 1966 to 1969. Tsien obtained PhD
PHD
PHD may refer to:*Ph.D., a doctorate of philosophy*Ph.D. , a 1980s British group*PHD finger, a protein sequence*PHD Mountain Software, an outdoor clothing and equipment company*PhD Docbook renderer, an XML renderer...

 in biophysics
Biophysics
Biophysics is an interdisciplinary science that uses the methods of physical science to study biological systems. Studies included under the branches of biophysics span all levels of biological organization, from the molecular scale to whole organisms and ecosystems...

 from Oxford in 1970.

From 1968 to 1970, Tsien was a Weir Junior Research Fellow at the University College of Oxford
University College, Oxford
.University College , is a constituent college of the University of Oxford in England. As of 2009 the college had an estimated financial endowment of £110m...

. From 1969 to 1970, Tsien was a teaching fellow at the Balliol College of Oxford
Balliol College, Oxford
Balliol College , founded in 1263, is one of the constituent colleges of the University of Oxford in England but founded by a family with strong Scottish connections....

.

In 1970, Tsien went back to the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

, became an assistant professor in the Department of Physiology at Yale University School of Medicine from 1970 to 1974. From 1974 to 1979, Tsien was an associate professor in the same department, and promoted to full professor in 1979 until 1988.

In 1988, Tsien went to Stanford and founded the Stanford University Department of Molecular and Cellular Physiology, where he also served the first chairman. From 1991 to 2001, Tsien was the Director Silvio Conte - National Institutes of Mental Health Center for Neuroscience Research. Since 1988, Tsien has been the George D. Smith Professor of Stanford Department of Molecular and Cellular Physiology. And since 2000, Tsien has been the Co-Director for the Stanford Brain Research Center.

Tsien did important work on calcium channel
Calcium channel
A Calcium channel is an ion channel which displays selective permeability to calcium ions. It is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels.-Comparison tables:...

s, their mechanisms and roles in cell signaling
Cell signaling
Cell signaling is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue...

 pathways. Tsien's research also helps us understand the long-term plasticity of synapse
Synapse
In the nervous system, a synapse is a structure that permits a neuron to pass an electrical or chemical signal to another cell...

s.

From 1987 to 1988, Tsien was the President
President
A president is a leader of an organization, company, trade union, university, or country.Etymologically, a president is one who presides, who sits in leadership...

 of the Society of General Physiologists. In August 2000, Tsien also served the Section Chair of Neurobiology of the United States National Academy of Sciences
United States National Academy of Sciences
The National Academy of Sciences is a corporation in the United States whose members serve pro bono as "advisers to the nation on science, engineering, and medicine." As a national academy, new members of the organization are elected annually by current members, based on their distinguished and...

. Tsien's youngest brother Roger Y. Tsien
Roger Y. Tsien
Roger Yonchien Tsien is a Chinese American biochemist and a professor at the Department of Chemistry and Biochemistry, University of California, San Diego...

, a cell biologist, won the 2008 Nobel Prize in Chemistry
Nobel Prize in Chemistry
The Nobel Prize in Chemistry is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outstanding contributions in chemistry, physics, literature,...

.

Selected honors & awards

  • 1985, Kenneth S. Cole Award (for contributions to membrane biophysics
    Membrane biophysics
    Membrane biophysics is the study of biological membranes using physical, computational, mathematical, and biophysical methods....

    )
  • 1991, 1995, 1999, Kaiser Award for Outstanding and Innovative Teaching, from Stanford University
  • 1993, Magnes Prize, from Hebrew University, Jerusalem
  • 1994, elected to the United States Institute of Medicine
    Institute of Medicine
    The Institute of Medicine is a not-for-profit, non-governmental American organization founded in 1970, under the congressional charter of the National Academy of Sciences...

  • 1996, Walter B. Cannon Memorial Award, from the American Physiological Society
    American Physiological Society
    The American Physiological Society was founded in 1887 with 28 members. Of them, 21 were graduates of medical schools, but only 12 had studied in schools that had a professor of physiology. Today, the APS has 10,500 members, most of whom hold doctoral degrees in medicine, physiology or other...

  • 1996, elected to the Academia Sinica
    Academia Sinica
    The Academia Sinica , headquartered in the Nangang District of Taipei, is the national academy of Taiwan. It supports research activities in a wide variety of disciplines, ranging from mathematical and physical sciences, to life sciences, and to humanities and social sciences.Academia Sinica has...

  • 1997, elected to the United States National Academy of Sciences
    United States National Academy of Sciences
    The National Academy of Sciences is a corporation in the United States whose members serve pro bono as "advisers to the nation on science, engineering, and medicine." As a national academy, new members of the organization are elected annually by current members, based on their distinguished and...

  • 1998, elected to the American Academy of Arts and Sciences
    American Academy of Arts and Sciences
    The American Academy of Arts and Sciences is an independent policy research center that conducts multidisciplinary studies of complex and emerging problems. The Academy’s elected members are leaders in the academic disciplines, the arts, business, and public affairs.James Bowdoin, John Adams, and...

  • 1999, elected Charter
    Charter
    A charter is the grant of authority or rights, stating that the granter formally recognizes the prerogative of the recipient to exercise the rights specified...

     to the Biophysical Society
    Biophysical Society
    The Biophysical Society is an organization consisting of over 9,000 researchers in academia, government, and industry. Based in the USA, its international membership has grown to about 1/3 of the total. Founded in 1957 by Ernest C...


External links

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