Ralph Paffenbarger
Encyclopedia
Ralph S. Paffenbarger, Jr. (October 21, 1922 – July 9, 2007, Santa Fe, New Mexico
Santa Fe, New Mexico
Santa Fe is the capital of the U.S. state of New Mexico. It is the fourth-largest city in the state and is the seat of . Santa Fe had a population of 67,947 in the 2010 census...

) was an epidemiologist, ultramarathon
Ultramarathon
An ultramarathon is any sporting event involving running longer than the traditional marathon length of .There are two types of ultramarathon events: those that cover a specified distance, and events that take place during specified time...

er, and professor at both Stanford University
Stanford University
The Leland Stanford Junior University, commonly referred to as Stanford University or Stanford, is a private research university on an campus located near Palo Alto, California. It is situated in the northwestern Santa Clara Valley on the San Francisco Peninsula, approximately northwest of San...

 School of Medicine and Harvard University School of Public Health
Harvard School of Public Health
The Harvard School of Public Health is one of the professional graduate schools of Harvard University, located in the Longwood Area of the Boston, Massachusetts neighborhood of Mission Hill, which is next to Harvard Medical School. HSPH is considered a significant school focusing on health in the...

.

Paffenbarger was internationally renowned for his classic study on the improvement in longevity
Longevity
The word "longevity" is sometimes used as a synonym for "life expectancy" in demography or known as "long life", especially when it concerns someone or something lasting longer than expected ....

 through regular lifetime physical activity, which confirmed prior evidence that more physically active people reduce their risk of heart disease
Heart disease
Heart disease, cardiac disease or cardiopathy is an umbrella term for a variety of diseases affecting the heart. , it is the leading cause of death in the United States, England, Canada and Wales, accounting for 25.4% of the total deaths in the United States.-Types:-Coronary heart disease:Coronary...

 and live longer. He published hundreds of papers on the relationship between exercise and longevity, and helped write the recommendations to exercise in the United States Surgeon General's
Surgeon General of the United States
The Surgeon General of the United States is the operational head of the Public Health Service Commissioned Corps and thus the leading spokesperson on matters of public health in the federal government...

 Report on Physical Activity and Health, published in 1996.

Early life and education

Paffenbarger grew up in Columbus, Ohio
Columbus, Ohio
Columbus is the capital of and the largest city in the U.S. state of Ohio. The broader metropolitan area encompasses several counties and is the third largest in Ohio behind those of Cleveland and Cincinnati. Columbus is the third largest city in the American Midwest, and the fifteenth largest city...

. Paffenbarger earned his MD
Doctor of Medicine
Doctor of Medicine is a doctoral degree for physicians. The degree is granted by medical schools...

 degree from Northwestern University Medical School
Feinberg School of Medicine
Northwestern University Feinberg School of Medicine, located in the Streeterville neighborhood of Chicago, Illinois and situated near Lake Michigan and the Magnificent Mile, is one of Northwestern University's 11 schools and colleges...

 during World War II
World War II
World War II, or the Second World War , was a global conflict lasting from 1939 to 1945, involving most of the world's nations—including all of the great powers—eventually forming two opposing military alliances: the Allies and the Axis...

, and his DrPH degree in epidemiology
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

 from Johns Hopkins University
Johns Hopkins University
The Johns Hopkins University, commonly referred to as Johns Hopkins, JHU, or simply Hopkins, is a private research university based in Baltimore, Maryland, United States...

.

Career

Early in his career, Paffenbarger engaged in polio research as an officer in the United States Public Health Service, focusing on the transmission and pathogenesis of polio. He worked with Dr. Jonas Salk
Jonas Salk
Jonas Edward Salk was an American medical researcher and virologist, best known for his discovery and development of the first safe and effective polio vaccine. He was born in New York City to parents from Ashkenazi Jewish Russian immigrant families...

 to develop the first effective polio vaccine
Polio vaccine
Two polio vaccines are used throughout the world to combat poliomyelitis . The first was developed by Jonas Salk and first tested in 1952. Announced to the world by Salk on April 12, 1955, it consists of an injected dose of inactivated poliovirus. An oral vaccine was developed by Albert Sabin...

.

In the mid 1950s, he shifted to chronic disease epidemiology and the search for causes of mental illness
Mental illness
A mental disorder or mental illness is a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which is not a part of normal development or culture. Such a disorder may consist of a combination of affective, behavioural,...

es associated with childbearing, site-specific cancers, and cardiovascular-hypertensive-metabolic diseases. After being urged by then President Dwight Eisenhower's physician to investigate heart disease, he began his landmark study of the relations between physical activity, chronic disease, and longevity.

Paffenbarger spent time at Harvard and the University of California, Berkeley
University of California, Berkeley
The University of California, Berkeley , is a teaching and research university established in 1868 and located in Berkeley, California, USA...

, where he served as adjunct professor of epidemiology, before joining the faculty at the Stanford School of Medicine in 1977. He became emeritus in 1993 in health research and policy at Stanford, after which he returned to UC Berkeley to join the department of human biodynamics.

Paffenbarger died at the age of 84, at his home in Santa Fe, New Mexico
Santa Fe, New Mexico
Santa Fe is the capital of the U.S. state of New Mexico. It is the fourth-largest city in the state and is the seat of . Santa Fe had a population of 67,947 in the 2010 census...

 on July 9, 2007 of heart failure.

Research

Over the course of almost five decades, Paffenbarger conducted some of largest and earliest scientific studies in epidemiology, which proved that increased exercise lowers the chance of death from heart disease. The study used periodic questionnaires to chronicle, over several decades, the personal characteristics, physical-activity levels, illnesses and deaths of over 50,000 college alumni. He continued to publish research findings from his studies until his own death, in 2007, at the age of 84, after a long battle with congestive heart disease.

College Alumni Health Study

In 1960, Paffenbarger began the landmark College Alumni Health Study, investigating the exercise habits of over 50,000 University of Pennsylvania
University of Pennsylvania
The University of Pennsylvania is a private, Ivy League university located in Philadelphia, Pennsylvania, United States. Penn is the fourth-oldest institution of higher education in the United States,Penn is the fourth-oldest using the founding dates claimed by each institution...

 and Harvard University
Harvard University
Harvard University is a private Ivy League university located in Cambridge, Massachusetts, United States, established in 1636 by the Massachusetts legislature. Harvard is the oldest institution of higher learning in the United States and the first corporation chartered in the country...

 alumni. The results of this study confirmed that more physically active people have a lower risk of coronary heart disease and live longer. Paffenbarger's Harvard alumni health study
Harvard alumni health study
The Harvard alumni health study is a cohort study focusing on the effect of exercise on coronary artery disease, strokes, diabetes, hypertension, cancer, obesity and mortality. Including only male, Harvard College graduates who began their studies between 1916 and 1950 and were still living in...

, of 17,000 male alumni who graduated between 1916 and 1950 , found that when the alumni were in their forties, vigorous exercise predicted greater longevity and lower risk of cardiovascular disease, and that so long as energy expenditure was equivalent, it was irrelevant whether the exercise was carried out in a single session or broken up. The study also found that as the energy expended increased, the risk of heart disease decreased. Those who remained very active into midlife stood a much better chance of surviving than moderately exercising and inactive alumni.

The College Alumni Health Study’s preliminary findings suggested that men burning 2,000 or more calories a week significantly lowered their risk of death from heart disease compared to more sedentary peers. Paffenbarger found that, among the 640 men in the study who had died of cardiovascular disease, the death rate for the most sedentary was nearly twice that for the most active. Regular exercise, the study also confirmed in the 1990s, reduced coronary death rates by 25 percent to 33 percent.

Running long

In 1967, when he was 45, Paffenbarger took up competitive running, and finished more than 150 marathon and ultramarathon
Ultramarathon
An ultramarathon is any sporting event involving running longer than the traditional marathon length of .There are two types of ultramarathon events: those that cover a specified distance, and events that take place during specified time...

 events. He ran the Boston Marathon
Boston Marathon
The Boston Marathon is an annual marathon hosted by the U.S. city of Boston, Massachusetts, on Patriots' Day, the third Monday of April. Begun in 1897 and inspired by the success of the first modern-day marathon competition in the 1896 Summer Olympics, the Boston Marathon is the world's oldest...

 22 times and the Western States Endurance Run
Western States Endurance Run
The Western States Endurance Run, known commonly as the Western States 100, is a 100-mile ultramarathon that takes place on trails in California's Sierra Nevada Mountains annually on the last full weekend of June. The race starts at the base of the Squaw Valley ski resort and finishes at the...

 five times.

Recognition

In 1996, Paffenbarger was a co-recipient of the first Olympic Prize for Sports Sciences for his work showing the link between physical activity and lowered risk of heart disease.

Publications

  • Paffenbarger, R. S., Hyde R.T., Wing, A.L., Hsieh, C.C., 'Physical activity, all-cause mortality, and longevity of college alumni', New England Journal of Medicine
    New England Journal of Medicine
    The New England Journal of Medicine is an English-language peer-reviewed medical journal published by the Massachusetts Medical Society. It describes itself as the oldest continuously published medical journal in the world.-History:...

     1986;314;605-13. PMID 3945246.
  • Ralph Paffenbarger, Eric Olsen. LifeFit: An Effective Exercise Program for Optimal Health and a Longer Life, (1996) Champaign, IL: Human Kinetics, ISBN 0-87322-429-9.
  • Paffenbarger, R. S.; Lee, I. M., 'A natural history of athleticism, health and longevity', Journal of Sports Sciences (1998)
  • Lee, I. M., Paffenbarger, R.S., 'How much physical activity is optimal for health? Methodological considerations', Research Quarterly for Exercise and Sport (1996)
  • Lee, I. M., Paffenbarger, R.S., 'Do physical activity and physical fitness avert premature mortality?' Exercise and Sport Sciences Reviews (1996)
  • Paffenbarger, R. S., Lee, I. M., 'Physical activity and fitness for health and longevity', Research Quarterly for Exercise and Sport (1996)
  • Blair, S. N., Wells, C. L., Weathers, R.D., Paffenbarger, R.S., 'Chronic disease: The physical activity dose-response controversy' (book chapter), Advances in Exercise Adherence (1994)
  • Paffenbarger, R. S., Hyde, R. T., Dow, A., 'Health benefits of physical activity' (book chapter), Benefits of leisure (1991)

External links

  • 'The College Alumni Health Study - A Précis', Stanford.edu
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