Pierre François Olive Rayer
Encyclopedia
Pierre François Olive Rayer (8 March 1793 - 10 September 1867) was a French physician
Physician
A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...

 who was a native of Saint Sylvain. He made important contributions in the fields of pathological anatomy
Anatomy
Anatomy is a branch of biology and medicine that is the consideration of the structure of living things. It is a general term that includes human anatomy, animal anatomy , and plant anatomy...

, physiology
Physiology
Physiology is the science of the function of living systems. This includes how organisms, organ systems, organs, cells, and bio-molecules carry out the chemical or physical functions that exist in a living system. The highest honor awarded in physiology is the Nobel Prize in Physiology or...

, comparative pathology
Pathology
Pathology is the precise study and diagnosis of disease. The word pathology is from Ancient Greek , pathos, "feeling, suffering"; and , -logia, "the study of". Pathologization, to pathologize, refers to the process of defining a condition or behavior as pathological, e.g. pathological gambling....

 and parasitology
Parasitology
Parasitology is the study of parasites, their hosts, and the relationship between them. As a biological discipline, the scope of parasitology is not determined by the organism or environment in question, but by their way of life...

.

He studied medicine at Caen
Caen
Caen is a commune in northwestern France. It is the prefecture of the Calvados department and the capital of the Basse-Normandie region. It is located inland from the English Channel....

, and afterwards in Paris
Paris
Paris is the capital and largest city in France, situated on the river Seine, in northern France, at the heart of the Île-de-France region...

 at the Ecole Pratique des Hautes Etudes
École pratique des hautes études
The École pratique des hautes études is a Grand Établissement in Paris, France. It is counted among France's most prestigious research and higher education institutions....

 and at the Hôtel-Dieu
Hôtel-Dieu de Paris
The Hôtel-Dieu de Paris is regarded as the oldest hospital in the city of Paris, France, and is the most central of the Assistance publique - hôpitaux de Paris hospitals. The hospital is linked to the Faculté de Médecine Paris-Descartes...

. He became an interne of medicine in 1813, and in 1818 earned his medical doctorate. Later he became a physician at Hôpital Saint-Antoine (1825), and at the Hôpital de la Charité
Hôpital de la Charité
Hôpital de la Charité was a hospital in Paris founded in the 17th century and closed in 1935.-History:In 1606, Marie de Médicis invited the Brothers Hospitallers of St. John of God to come to France. The Abbot of Saint-Germain-des-Prés granted them the use of its former Saint-Père chapel, which...

 (1832), and was also a consultant-physician to King Louis-Philippe. In 1862 he attained the chair of comparative anatomy at the Faculty of Medicine of Paris.

In 1837 Rayer discovered that the fatal equine disease known as glanders
Glanders
Glanders is an infectious disease that occurs primarily in horses, mules, and donkeys. It can be contracted by other animals such as dogs, cats and goats...

 was contagious to other species including humans. Between 1837 and 1841 he published a three-volume book on diseases of the kidney
Kidney
The kidneys, organs with several functions, serve essential regulatory roles in most animals, including vertebrates and some invertebrates. They are essential in the urinary system and also serve homeostatic functions such as the regulation of electrolytes, maintenance of acid–base balance, and...

 titled Traité des maladies des reins. In 1850 Rayer published a work that provided the first comprehensive description of anthrax
Anthrax
Anthrax is an acute disease caused by the bacterium Bacillus anthracis. Most forms of the disease are lethal, and it affects both humans and other animals...

. In this treatise he documented studies he performed with physician Casimir Davaine
Casimir Davaine
Casimir Davaine was a French physician known for his work in the field of microbiology. He was a native of Saint-Amand-les-Eaux, department of Nord....

 (1812-1882) concerning Bacillus anthracis.

Rayer was a member of the Académie de médecine and the Académie des Sciences, and co-founder of the Société de Biologie, of which he was also president. He maintained friendships with several influential people in France; including naturalist
Naturalist
Naturalist may refer to:* Practitioner of natural history* Conservationist* Advocate of naturalism * Naturalist , autobiography-See also:* The American Naturalist, periodical* Naturalism...

 Isidore Geoffroy Saint-Hilaire
Isidore Geoffroy Saint-Hilaire
Isidore Geoffroy Saint-Hilaire was a French zoologist and an authority on deviation from normal structure. He coined the term ethology.He was born in Paris, the son of Étienne Geoffroy Saint-Hilaire...

, novelist George Sand
George Sand
Amantine Lucile Aurore Dupin, later Baroness Dudevant , best known by her pseudonym George Sand , was a French novelist and memoirist.-Life:...

, philosopher Emile Littré
Émile Littré
Émile Maximilien Paul Littré was a French lexicographer and philosopher, best known for his Dictionnaire de la langue française, commonly called "The Littré".-Biography:Émile Littré was born in Paris...

, and several disciples of Henri de Saint-Simon
Claude Henri de Rouvroy, comte de Saint-Simon
Claude Henri de Rouvroy, comte de Saint-Simon, often referred to as Henri de Saint-Simon was a French early socialist theorist whose thought influenced the foundations of various 19th century philosophies; perhaps most notably Marxism, positivism and the discipline of sociology...

.

Eponym
Eponym
An eponym is the name of a person or thing, whether real or fictitious, after which a particular place, tribe, era, discovery, or other item is named or thought to be named...

s associated with Pierre Rayer:
  • Rayer's disease: A disorder characterized by chronic jaundice
    Jaundice
    Jaundice is a yellowish pigmentation of the skin, the conjunctival membranes over the sclerae , and other mucous membranes caused by hyperbilirubinemia . This hyperbilirubinemia subsequently causes increased levels of bilirubin in the extracellular fluid...

    , splenomegaly
    Splenomegaly
    Splenomegaly is an enlargement of the spleen. The spleen usually lies in the left upper quadrant of the human abdomen. It is one of the four cardinal signs of hypersplenism, some reduction in the number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any...

    , and hepatomegaly
    Hepatomegaly
    Hepatomegaly is the condition of having an enlarged liver. It is a nonspecific medical sign having many causes, which can broadly be broken down into infection, direct toxicity, hepatic tumours, or metabolic disorder. Often, hepatomegaly will present as an abdominal mass...

    .
  • Rayer's nodules: An xanthoma
    Xanthoma
    A xanthoma , from Greek xanthos, ξανθος, "yellow", is a deposition of yellowish cholesterol-rich material in tendons or other body parts in various disease states...

    ; yellowish nodules on the skin (often on the eyelids).
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