NCOA6 - AbsoluteAstronomy.com

Nuclear receptor coactivator 6 is a protein

Protein

Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

that in humans is encoded by the NCOA6 gene

Gene

A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

Interactions

NCOA6 has been shown to interact

Protein-protein interaction

Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

with Ku70, RBBP5

RBBP5

Retinoblastoma-binding protein 5 is a protein that in humans is encoded by the RBBP5 gene.-Interactions:RBBP5 has been shown to interact with NCOA6, MLL3, ASCL2 and MLL.-Further reading:...

, E2F1

E2F1

Transcription factor E2F1 is a protein that in humans is encoded by the E2F1 gene.-Interactions:E2F1 has been shown to interact with NCOA6, Retinoblastoma-like protein 1, Retinoblastoma protein, GTF2H1, SKP2, PURA, NPDC1, Sp2 transcription factor, Sp1 transcription factor, CUL1, ARID3A, TOPBP1,...

, Retinoblastoma protein

Retinoblastoma protein

The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in the majority types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide...

, CREB-binding protein, Activating transcription factor 2

Activating transcription factor 2

Activating transcription factor 2, also known as ATF2, is a protein that, in humans, is encoded by the ATF2 gene.-Function:This gene encodes a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds to the cAMP-responsive element , an octameric...

, HSF1

HSF1

Heat shock factor protein 1 is a protein that in humans is encoded by the HSF1 gene.-Function:The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress...

, HBXIP

HBXIP

Hepatitis B virus X-interacting protein is a protein that in humans is encoded by the HBXIP gene.-Further reading:...

, TGS1

TGS1

Trimethylguanosine synthase is an enzyme that in humans is encoded by the TGS1 gene.-Interactions:TGS1 has been shown to interact with NCOA6, MED1, EP300, CREB-binding protein and EED.-Further reading:...

, TUBB

TUBB

Tubulin beta chain is a protein that in humans is encoded by the TUBB gene.-Interactions:TUBB has been shown to interact with NCOA6 and SYT9.-Further reading:...

, TUBA4A

TUBA4A

Tubulin alpha-4A chain is a protein that in humans is encoded by the TUBA4A gene.-Interactions:TUBA4A has been shown to interact with NCOA6 and APC.-Further reading:...

, Thyroid hormone receptor beta

Thyroid hormone receptor beta

Thyroid hormone receptor beta also known as nuclear receptor subfamily 1, group A, member 2 , is a nuclear receptor protein that in humans is encoded by the THRB gene.- Function :...

, Retinoic acid receptor alpha

Retinoic acid receptor alpha

Retinoic acid receptor alpha , also known as NR1B1 is a nuclear receptor that in humans is encoded by the RARA gene.- Function :...

, Src

Src (gene)

Proto-oncogene tyrosine-protein kinase Src is an enzyme that in humans is encoded by the SRC gene.Src is a proto-oncogene encoding a tyrosine kinase originally discovered by J. Michael Bishop and Harold E. Varmus, for which they won the 1989 Nobel Prize in Physiology or Medicine. It belongs to a...

, Thyroid hormone receptor alpha

Thyroid hormone receptor alpha

Thyroid hormone receptor alpha also known as nuclear receptor subfamily 1, group A, member 1 , is a nuclear receptor protein that in humans is encoded by the THRA gene.- Function :...

, DNA-PKcs, Androgen receptor

Androgen receptor

The androgen receptor , also known as NR3C4 , is a type of nuclear receptor that is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus...

, HIST2H3C

HIST2H3C

Histone H3.2 is a protein that in humans is encoded by the HIST2H3C gene.-Further reading:...

, MLL3

MLL3

Histone-lysine N-methyltransferase MLL3 is an enzyme that in humans is encoded by the MLL3 gene.-Interactions:MLL3 has been shown to interact with NCOA6 and RBBP5.- External links :...

, Ku80, Liver X receptor beta

Liver X receptor beta

Liver X receptor beta is a member of the nuclear receptor family of transcription factors. LXR-β is encoded by the gene .- Function :...

, Estrogen receptor alpha

Estrogen receptor alpha

Estrogen receptor alpha , also known as NR3A1 , is a nuclear receptor that is activated by the sex hormone estrogen...

, Estrogen receptor beta

Estrogen receptor beta

Estrogen receptor beta , also known as NR3A2 , is a nuclear receptor which is activated by the sex hormone estrogen. In humans, ER-β is encoded by the ESR2 gene.- Function :...

, EP300

EP300

E1A binding protein p300 also known as EP300 or p300 is a protein that, in humans, is encoded by the EP300 gene. This protein regulates the activity of many genes in tissues throughout the body...

, ASCL2

ASCL2

Achaete-scute complex homolog 2 , also known as ASCL2, is an imprinted human gene.-Interactions:ASCL2 has been shown to interact with NCOA6 and RBBP5.-Further reading:...

and Retinoid X receptor alpha

Retinoid X receptor alpha

Retinoid X receptor alpha , also known as NR2B1 is a nuclear receptor that in humans is encoded by the RXRA gene.- Function :...