Lawrence Garfinkel
Encyclopedia
Lawrence Garfinkel was an American epidemiologist involved in demonstrating the link between smoking
Tobacco smoking
Tobacco smoking is the practice where tobacco is burned and the resulting smoke is inhaled. The practice may have begun as early as 5000–3000 BCE. Tobacco was introduced to Eurasia in the late 16th century where it followed common trade routes...

 and lung cancer
Lung cancer
Lung cancer is a disease characterized by uncontrolled cell growth in tissues of the lung. If left untreated, this growth can spread beyond the lung in a process called metastasis into nearby tissue and, eventually, into other parts of the body. Most cancers that start in lung, known as primary...

.

After graduating from high school at age 15, he attended City College of New York
City College of New York
The City College of the City University of New York is a senior college of the City University of New York , in New York City. It is also the oldest of the City University's twenty-three institutions of higher learning...

. His college career was interrupted by World War II
World War II
World War II, or the Second World War , was a global conflict lasting from 1939 to 1945, involving most of the world's nations—including all of the great powers—eventually forming two opposing military alliances: the Allies and the Axis...

. After the attack on Pearl Harbor
Attack on Pearl Harbor
The attack on Pearl Harbor was a surprise military strike conducted by the Imperial Japanese Navy against the United States naval base at Pearl Harbor, Hawaii, on the morning of December 7, 1941...

, Garfinkel joined the Army
United States Army
The United States Army is the main branch of the United States Armed Forces responsible for land-based military operations. It is the largest and oldest established branch of the U.S. military, and is one of seven U.S. uniformed services...

, serving in France
France
The French Republic , The French Republic , The French Republic , (commonly known as France , is a unitary semi-presidential republic in Western Europe with several overseas territories and islands located on other continents and in the Indian, Pacific, and Atlantic oceans. Metropolitan France...

. After months in hospital after being seriously wounded, he returned to City College earning bachelor's degree in statistics
Statistics
Statistics is the study of the collection, organization, analysis, and interpretation of data. It deals with all aspects of this, including the planning of data collection in terms of the design of surveys and experiments....

. He later earned master's degree from Columbia University
Columbia University
Columbia University in the City of New York is a private, Ivy League university in Manhattan, New York City. Columbia is the oldest institution of higher learning in the state of New York, the fifth oldest in the United States, and one of the country's nine Colonial Colleges founded before the...

.

An early job at the American Cancer Society
American Cancer Society
The American Cancer Society is the "nationwide community-based voluntary health organization" dedicated, in their own words, "to eliminating cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering from cancer, through research, education, advocacy, and...

, where he was hired a statistical clerk, turned into a 43 year career. Over time, he learned the tools of epidemiology and rose to become a leader in the field.

In the early 1950s, scientists began to suspect the link between smoking and cancer, but statistically valid evidence didn't yet exist. An early study that he performed with his seniors, tracking more than 150,000 people for about 3 and a half years, demonstrated a significant correlation. This landmark study was just the first of numerous, increasingly ambitious studies, tracking more than a million people each.

The data from these studies—still being used today—not only conclusively demonstrated the links between smoking and lung cancer, but also collected valuable data on obesity, alcohol use, other cancers, and various other factors.

Garfinkel also worked on studies of the pathology of lung cancer and precancer, and demonstrated statistical correlation between length of smoking and the amount of tissue change. This provided a physiological underpinning to the disease correlations previously established.
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