Julien Hoffman
Encyclopedia
Professor Julien I.E. Hoffman, FRCP  (born 1924 in Johannesburg
Johannesburg
Johannesburg also known as Jozi, Jo'burg or Egoli, is the largest city in South Africa, by population. Johannesburg is the provincial capital of Gauteng, the wealthiest province in South Africa, having the largest economy of any metropolitan region in Sub-Saharan Africa...

) is a South African-American pediatric cardiologist and professor emeritus of pediatrics and a senior member of the Cardiovascular Research Institute at the University of California, San Francisco
University of California, San Francisco
The University of California, San Francisco is one of the world's leading centers of health sciences research, patient care, and education. UCSF's medical, pharmacy, dentistry, nursing, and graduate schools are among the top health science professional schools in the world...

. He has also worked at the Moffitt-Long Hospital at the UCSF Medical Center
UCSF Medical Center
The University of California, San Francisco Medical Center is a world renowned hospital in research and a teaching hospital in San Francisco, California. It is one of the leading hospitals in the United States and with the UCSF School of Medicine has been the site of various breakthroughs in all...

, and serves on the medical advisory committee for the SIDS Alliance.

Early years

In the 1940s, while an Honors student working on spermatogenesis
Spermatogenesis
Spermatogenesis is the process by which male primary germ cells undergo division, and produce a number of cells termed spermatogonia, from which the primary spermatocytes are derived. Each primary spermatocyte divides into two secondary spermatocytes, and each secondary spermatocyte into two...

, Hoffman developed a close relationship with Sydney Brenner
Sydney Brenner
Sydney Brenner, CH FRS is a South African biologist and a 2002 Nobel prize in Physiology or Medicine laureate, shared with H...

 and Phillip V. Tobias
Phillip V. Tobias
Phillip Vallentine Tobias is a South African palaeoanthropologist and Professor Emeritus at the University of the Witwatersrand in Johannesburg...

. Hoffman graduated from the University of the Witwatersrand
University of the Witwatersrand
The University of the Witwatersrand, Johannesburg is a South African university situated in the northern areas of central Johannesburg. It is more commonly known as Wits University...

 in Johannesburg
Johannesburg
Johannesburg also known as Jozi, Jo'burg or Egoli, is the largest city in South Africa, by population. Johannesburg is the provincial capital of Gauteng, the wealthiest province in South Africa, having the largest economy of any metropolitan region in Sub-Saharan Africa...

, South Africa
South Africa
The Republic of South Africa is a country in southern Africa. Located at the southern tip of Africa, it is divided into nine provinces, with of coastline on the Atlantic and Indian oceans...

 in 1949 and began an internship in Internal Medicine at Johannesburg General Hospital
Johannesburg General Hospital
'The Charlotte Maxeke Johannesburg Academic Hospital , nicknamed Joburg Gen is an accredited general hospital in Parktown, Johannesburg, Gauteng, South Africa. It has 1088 beds...

 in 1950 and in Surgery there in 1951. In 1952 he began an Internship in Internal Medicine at Central Middlesex Hospital
Central Middlesex Hospital
Central Middlesex hospital is in the centre of the Park Royal business estate, on the border of two London boroughs, Brent and Ealing.-Hospital role:CMH is a teaching hospital of Imperial College School of Medicine and part of the...

, in London
London
London is the capital city of :England and the :United Kingdom, the largest metropolitan area in the United Kingdom, and the largest urban zone in the European Union by most measures. Located on the River Thames, London has been a major settlement for two millennia, its history going back to its...

, England.

Career

Hoffman became a Registrar in Internal Medicine at Central Middlesex Hospital in 1953 and the same position at Johannesburg General Hospital in 1955. He became a Research Fellow in Cardiology at the Royal Postgraduate Medical School
Royal Postgraduate Medical School
The Royal Postgraduate Medical School was an independent medical school, based primarily at Hammersmith Hospital in west London. In 1988, the school merged with the Institute of Obstetrics & Gynaecology, and in 1997 became part of the Imperial College School of Medicine.-History:The medical school...

 in London, in 1957, a fellow in Pediatric Cardiology at the Children's Hospital, Boston in 1959 and Senior Fellow in Cardiology at the Cardiovascular Research Institute in San Francisco in 1960, working there since 1966. Hoffman obtained his diplomate from the American Board of Pediatrics in 1968 and his MD in 1970.

In 1989, Hoffman became Chairman of the UCSF Medical Center's Cardiovascular Research Institute Animal Research Committee and in 1991 chairman on the Oversight Committee on Fetal Surgery. He became Professor Emeritus of Pediatrics in 1994. He has considerable expertise in sudden infant death syndrome
Sudden infant death syndrome
Sudden infant death syndrome is marked by the sudden death of an infant that is unexpected by medical history, and remains unexplained after a thorough forensic autopsy and a detailed death scene investigation. An infant is at the highest risk for SIDS during sleep, which is why it is sometimes...

 (SIDS), and is cited as providing a valuable contribution to the field of cardiology. Hoffman also serves on the editorial board of Circulation Research Journal of the American Heart Association
American Heart Association
The American Heart Association is a non-profit organization in the United States that fosters appropriate cardiac care in an effort to reduce disability and deaths caused by cardiovascular disease and stroke. It is headquartered in Dallas, Texas...

 and is a reviewer for journals such as American Journal of Cardiology
American Journal of Cardiology
The American Journal of Cardiology is a peer-reviewed scientific journal in the field of cardiology and general cardiovascular disease. It is independent from the American College of Cardiology....

, the American Journal of Genetics, the American Review of Respiratory Disease
American Journal of Respiratory and Critical Care Medicine
The American Journal of Respiratory and Critical Care Medicine is a semi monthly medical journal published in two yearly volumes by the American Thoracic Society covering the pathophysiology and treatment of diseases that affect the respiratory system. The journal also publishes review articles in...

Circulation
Circulation (journal)
Circulation is a scientific journal published by Lippincott Williams & Wilkins for the American Heart Association. The journal publishes articles related to research in and the practice of cardiovascular diseases, including observational studies, clinical trials, epidemiology, health services and...

, Pediatrics
Pediatrics (journal)
Pediatrics is an official peer-reviewed journal of the American Academy of Pediatrics. In the inaugural January 1948 issue, the journal's first editor, Hugh McCulloch, articulated the journal's vision: "The content of the journal is... intended to encompass the needs of the whole child in his...

, and The Journal of Pediatrics
The Journal of Pediatrics
The Journal of Pediatrics is a peer-reviewed monthly medical journal that covers all aspects of pediatrics. Readership for The Journal of Pediatrics includes pediatricians, researchers, pediatric investigators, and all those who diagnose and treat infants and children. The Journal of Pediatrics...

. Hoffman has written books such as The Natural and Unnatural History of Congenital Heart Disease (2009).

According to the University of California, his research is "currently related to the natural history of different congenital heart diseases and the results of surgery or other forms of treatment for these lesions in different age groups. He continues to study aspects of myocardial contraction and coronary blood flow in collaboration with investigators at other institutions."

Hoffman lives in Tiburon, California
Tiburon, California
Tiburon is an incorporated town in Marin County, California. It occupies most of the Tiburon Peninsula, which reaches south into the San Francisco Bay. The smaller city of Belvedere occupies the south-east part of the peninsula and is contiguous with Tiburon...

.
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