Human rhinovirus internal cis-acting regulatory element (CRE)
Encyclopedia
Human rhinovirus internal cis-acting regulatory element (CRE) is
a CRE
from the human rhinovirus
es. The CRE is located within the genome segment encoding the capsid
proteins so is found in a protein coding region. The element is essential for efficient viral
replication and it has been suggested that the CRE is required for initiation of minus-strand RNA
synthesis.
a CRE
Cis-regulatory element
A cis-regulatory element or cis-element is a region of DNA or RNA that regulates the expression of genes located on that same molecule of DNA . This term is constructed from the Latin word cis, which means "on the same side as". These cis-regulatory elements are often binding sites for one or...
from the human rhinovirus
Rhinovirus
Human rhinoviruses are the most common viral infective agents in humans and are the predominant cause of the common cold. Rhinovirus infection proliferates in temperatures between 33–35 °C , and this may be why it occurs primarily in the nose...
es. The CRE is located within the genome segment encoding the capsid
Capsid
A capsid is the protein shell of a virus. It consists of several oligomeric structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The capsid encloses the genetic...
proteins so is found in a protein coding region. The element is essential for efficient viral
Virus
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...
replication and it has been suggested that the CRE is required for initiation of minus-strand RNA
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....
synthesis.
See also
- Human parechovirus 1 (HPeV1) cis regulatory element (CRE)Human parechovirus 1 (HPeV1) cis regulatory element (CRE)The Human Parechovirus 1 cis regulatory element is an RNA element which is located in the 5'-terminal 112 nucleotides of the genome of human parechovirus 1 . The element consists of two stem-loop structures together with a pseudoknot...
- Rotavirus cis-acting replication element (CRE)Rotavirus cis-acting replication element (CRE)This family represents a rotavirus cis-acting replication element found at the 3'-end of rotavirus mRNAs. The family is thought to promote the synthesis of minus strand RNA to form viral dsRNA....