The Drosophilinae are the largest subfamily in the Drosophilidae

Drosophilidae

Drosophilidae is a diverse, cosmopolitan family of flies, which includes fruit flies. Another family of flies called Tephritidae also includes fruit flies. The best known species of Drosophilidae is Drosophila melanogaster, within the genus Drosophila, and this species Is used extensively for...

. The other subfamily is the Steganinae

Steganinae

The Steganinae Hendel, 1917, is the smaller of two subfamilies in the fruit fly family Drosophilidae. The other subfamily is the Drosophilinae.- Diagnosis :...

.

Phylogeny

Many molecular studies have addressed small parts of the phylogenetic tree

Phylogenetic tree

A phylogenetic tree or evolutionary tree is a branching diagram or "tree" showing the inferred evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical and/or genetic characteristics...

. Most of these studies are limited to species of the genus Drosophila

Drosophila

Drosophila is a genus of small flies, belonging to the family Drosophilidae, whose members are often called "fruit flies" or more appropriately pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit...

. The genus Drosophila is paraphyletic as several genera, such as Zaprionus, Scaptomyza and Lordiphosa, are positioned within the genus

Genus

In biology, a genus is a low-level taxonomic rank used in the biological classification of living and fossil organisms, which is an example of definition by genus and differentia...

. Position of the bolded species in the phylogenetic tree

Phylogenetic tree

A phylogenetic tree or evolutionary tree is a branching diagram or "tree" showing the inferred evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical and/or genetic characteristics...

 is at least reasonably well supported by existing molecular evidence.
Tribe: Drosophilini

Subtribe: Colocasiomyina

Genus: Baeodrosophila

Genus: Colocasiomyia

Genus: Palmomyia

Genus: Palmophila

Subtribe: Drosophilina

Infratribe: Drosophiliti

Genus: Bialba

Genus: Calodrosophila

Genus: Celidosoma

Genus: Chymomyza

Genus: Dicladochaeta

Genus: Hypselothyrea

Genus: Jeannelopsis

Genus: Lissocephala

Genus: Marquesia

Genus: Microdrosophila

Genus: Mulgravea

Genus: Neotanygastrella

Genus: Paraliodrosophila

Genus: Poliocephala

Genus: Protochymomyza

Genus: Scaptodrosophila

Genus: Sphaerogastrella

Genus: Styloptera

Genus: Tambourella

Genus: Zaropunis

Genus: Drosophila

Drosophila

Drosophila is a genus of small flies, belonging to the family Drosophilidae, whose members are often called "fruit flies" or more appropriately pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit...

including the following genera:

• Genus: Dettopsomyia
• Genus: Dichaetophora
• Genus: Hirtodrosophila
  Hirtodrosophila
  Hirtodrosophila is a genus of fruit fly from the family Drosophilidae. Formally Hirtodrosophila was a subgenus of the genus Drosophila, but was raised to the status of genus on 1990 by Grimaldi.-Description:...
  
  
• Genus: Liodrosophila
• Genus: Lordiphosa
• Genus: Mycodrosophila
• Genus: Paramycodrosophila
• Genus: Phorticella
• Genus: Samoaia
• Genus: Scaptomyza
• Genus: Zaprionus
  Zaprionus
  The genus Zaprionus belongs to the family fruit fly Drosophilidae and is positioned within the paraphyletic genus Drosophila. All species are easily recognized by the white longitudinal stripes across the head and thorax. The genus is subdivided in two subgenera, based on the presence of an even ...
  
  
• Genus: Zygothrica

Infratribe: Laccodrosophiliti

Genus: Zapriothrica

Genus: Laccodrosophila

Tribe: Cladochaetini

Genus: Cladochaeta

Genus: Diathoneura

Tribe unknown:

Genus: Miomyia

Genus: Collessia

Genus: Balara

For species within the various genera, see Taxodros