XII International AIDS Conference, 1998
Encyclopedia
The XII International AIDS Conference was held in Geneva
Geneva
Geneva In the national languages of Switzerland the city is known as Genf , Ginevra and Genevra is the second-most-populous city in Switzerland and is the most populous city of Romandie, the French-speaking part of Switzerland...

, Switzerland
Switzerland
Switzerland name of one of the Swiss cantons. ; ; ; or ), in its full name the Swiss Confederation , is a federal republic consisting of 26 cantons, with Bern as the seat of the federal authorities. The country is situated in Western Europe,Or Central Europe depending on the definition....

 from 28 June - 3 July, 1998. The theme of the conference was "Bridging the Gap."

Topics covered

The Journal of the American Medical Association
Journal of the American Medical Association
The Journal of the American Medical Association is a weekly, peer-reviewed, medical journal, published by the American Medical Association. Beginning in July 2011, the editor in chief will be Howard C. Bauchner, vice chairman of pediatrics at Boston University’s School of Medicine, replacing ...

 (JAMA) devoted the July issue of their magazine to HIV topics to support the conference, and chose especially to focus on two studies which would be presented at the conference. One focus was Roy Gulick's study on combination therapy for reducing viral load in HIV positive persons, in which AZT
Zidovudine
Zidovudine or azidothymidine is a nucleoside analog reverse-transcriptase inhibitor , a type of antiretroviral drug used for the treatment of HIV/AIDS. It is an analog of thymidine....

, 3TC
Lamivudine
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor .It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV.Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV...

 and indinavir
Indinavir
Indinavir is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV infection and AIDS.-History:...

 were shown to cause study participants to lower their viral load to undetectable levels. The other was Michael Giordano's study which showed that HIV positive mothers could reduce the risk of transmission of HIV to their child by elective cesarean section, taking AZT before delivery of the child, and taking AZT intravenously during the delivery.

Price of drugs

The Gay Men's Health Crisis
Gay Men's Health Crisis
The Gay Men's Health Crisis is a New York City-based non-profit, volunteer-supported and community-based AIDS service organization that has led the United States in the fight against AIDS.-1980s:...

 stated that drug marketing for Efavirenz
Efavirenz
Efavirenz is a non-nucleoside reverse transcriptase inhibitor and is used as part of highly active antiretroviral therapy for the treatment of a human immunodeficiency virus type 1....

 was part of this conference and that over 100 organizations worldwide had come together to issue a "Fair Price Consensus Statement" to guide policymakers on regulating the pricing of drugs. The issue was that Efavirenz was slated to go to market costing an average of $5000 per year and its efficacy was not proven over existing treatments, and GMHC and others were calling for expert oversight, pricing at rates which average people could afford, and greater community involvement in HIV/AIDS issues in general.

Response

Lancet
The Lancet
The Lancet is a weekly peer-reviewed general medical journal. It is one of the world's best known, oldest, and most respected general medical journals...

 editor Richard Horton stated his belief that the conference failed to facilitate discussion between the developed world and the developing world, and thus failed to keep to its advertised theme of "bridging the gap."

Further reading

Roy M. Gulick, MD, MPH; John W. Mellors, MD; Diane Havlir et al., Simultaneous vs Sequential Initiation of Therapy With Indinavir, Zidovudine, and Lamivudine for HIV-1 Infection, JAMA
Journal of the American Medical Association
The Journal of the American Medical Association is a weekly, peer-reviewed, medical journal, published by the American Medical Association. Beginning in July 2011, the editor in chief will be Howard C. Bauchner, vice chairman of pediatrics at Boston University’s School of Medicine, replacing ...

, July 1, 1998—Vol 280, No. 1.

External links

  • Event summary published by The Body
    The Body
    - Entertainment :* The Body , a short story by Camillo Boito* The Body , a novel written by Stephen King* The Body , a novel by Richard Sapir* The Body , a documentary about the human anatomy...

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