TNKS
Encyclopedia
Tankyrase-1 is an enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...

 that in humans is encoded by the TNKS gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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Interactions

TNKS has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with MCL1
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 is a protein that in humans is encoded by the MCL1 gene.- Function :The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been...

, TNKS1BP1
TNKS1BP1
182 kDa tankyrase-1-binding protein is an enzyme that in humans is encoded by the TNKS1BP1 gene.-Further reading:...

, FNBP1
FNBP1
Formin-binding protein 1 is a protein that in humans is encoded by the FNBP1 gene.-Interactions:FNBP1 has been shown to interact with SNX2, DNM1, TNKS, Fas ligand and AKAP9.-Further reading:...

 and TERF1
TERF1
Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene.-Interactions:TERF1 has been shown to interact with SALL1, MAPRE1, NME1, TNKS2, Ataxia telangiectasia mutated, TINF2, TNKS, PINX1 and Abl gene....

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Further reading

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