TERF1
Encyclopedia
Telomeric repeat-binding factor 1 is a protein
that in humans is encoded by the TERF1 gene
.
with SALL1
, MAPRE1
, NME1
, TNKS2
, Ataxia telangiectasia mutated
, TINF2
, TNKS
, PINX1
and Abl gene
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the TERF1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
TERF1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with SALL1
SALL1
Sal-like 1 , also known as SALL1, is a protein which in humans is encoded by the SALL1 gene. As the full name suggests, it is one of the human versions of the spalt gene known in Drosophila.- Function :...
, MAPRE1
MAPRE1
Microtubule-associated protein RP/EB family member 1 is a protein that in humans is encoded by the MAPRE1 gene.-Further reading:...
, NME1
NME1
Nucleoside diphosphate kinase A is an enzyme that in humans is encoded by the NME1 gene. It is thought to be a metastasis suppressor.-Interactions:...
, TNKS2
TNKS2
Tankyrase-2 is an enzyme that in humans is encoded by the TNKS2 gene.-Interactions:TNKS2 has been shown to interact with GRB14, TERF1 and Cystinyl aminopeptidase.-Further reading:...
, Ataxia telangiectasia mutated
Ataxia telangiectasia mutated
Ataxia telangiectasia mutated is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis...
, TINF2
TINF2
TERF1-interacting nuclear factor 2 is a protein that in humans is encoded by the TINF2 gene.-Interactions:TINF2 has been shown to interact with ACD, POT1 and TERF1.-External links:*...
, TNKS
TNKS
Tankyrase-1 is an enzyme that in humans is encoded by the TNKS gene.-Interactions:TNKS has been shown to interact with MCL1, TNKS1BP1, FNBP1 and TERF1.-Further reading:...
, PINX1
PINX1
PIN2-interacting protein 1, also known as PINX1, is a human gene.-Interactions:PINX1 has been shown to interact with MCRS1, TERF1 and Telomerase reverse transcriptase.-Further reading:...
and Abl gene
Abl gene
V-abl Abelson murine leukemia viral oncogene homolog 1 also known as ABL1 is a protein that, in humans, is encoded by the ABL1 gene located on chromosome 9.- Function :...
.