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Spirometry



 
 


Spirometry (meaning the measuring of breath) is the most common of the Pulmonary Function Tests (PFTs), measuring lung
Lung

The lung is the essential respiration organ in air-breathing animals, including most tetrapods, a few fish and a few snails. In mammals and the more complex life forms, the two lungs are located in the chest on either side of the heart....
 function, specifically the measurement of the amount (volume) and/or speed (flow) of air that can be inhaled and exhaled.






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Flow Volume Loop


Spirometry (meaning the measuring of breath) is the most common of the Pulmonary Function Tests (PFTs), measuring lung
Lung

The lung is the essential respiration organ in air-breathing animals, including most tetrapods, a few fish and a few snails. In mammals and the more complex life forms, the two lungs are located in the chest on either side of the heart....
 function, specifically the measurement of the amount (volume) and/or speed (flow) of air that can be inhaled and exhaled. Spirometry is an important tool used for generating pneumotachographs which are helpful in assessing conditions such as asthma
Asthma

Asthma is a common chronic obstructive pulmonary disease, in which the Lung constrict, become inflammation, and are lined with excessive amounts of thickened mucus, often in response to one or more triggers....
, pulmonary fibrosis, cystic fibrosis
Cystic fibrosis

Cystic Fibrosis is a Genetic disorder affecting the exocrine glands of the lungs, liver, pancreas, and intestines, causing progressive disability due to multisystem failure....
, and COPD
COPD

Chronic obstructive pulmonary disease is a group of diseases of the lungs in which the airways become narrowed. This leads to a limitation of the flow of air to and from the lungs causing shortness of breath....
.

Spirometry testing


The spirometry test is performed using a device called a spirometer
Spirometer

A spirometer is an apparatus for measuring the volume of air inspired and expired by the lungs. It is a precision differential pressure transducer for the measurements of respiration flow rates....
, which comes in several different varieties. Most spirometers display the following graphs:
  • a volume-time curve, showing volume (liters) along the Y-axis and time (seconds) along the X-axis
  • a flow-volume loop, which graphically depicts the rate of airflow on the Y-axis and the total volume inspired or expired on the X-axis


The most commonly used guidelines for spirometric testing and interpretation are set by the American Thoracic Society
American Thoracic Society

American Thoracic Society , established in 1905, is an independently incorporated, international, educational and scientific society, serving its 18,000 members world-wide who are dedicated in respiratory and critical care medicine....
 (ATS) and the European Respiratory Society (ERS).

Procedure

The basic FVC test varies slightly depending on the equipment used.

Generally, the patient is asked to take the deepest breath they can, and then exhale into the sensor as hard as possible, for as long as possible. It is sometimes directly followed by a rapid inhalation (inspiration), in particular when assessing possible upper airway obstruction. Sometimes, the test will be preceded by a period of quiet breathing in and out from the sensor (tidal volume), or the rapid breath in (forced inspiratory part) will come before the forced exhalation.

During the test, soft nose clips may be used to prevent air escaping through the nose. Filter mouthpieces may be used to prevent the spread of microorganisms, particularly for inspiratory maneuvers.

Limitations of test

The maneuver is highly dependent on patient cooperation and effort, and is normally repeated at least three times to ensure reproducibility. Since results are dependent on patient cooperation, FEV1* and FVC can only be underestimated, never overestimated.(*FEV1 can be overestimated in people with some diseases - a softer blow can reduce the spasm or collapse of lung tissue to elevate the measure)

Due to the patient cooperation required, spirometry can only be used on children old enough to comprehend and follow the instructions given (typically about 4-5 years old), and only on patients who are able to understand and follow instructions - thus, this test is not suitable for patients who are unconscious, heavily sedated, or have limitations that would interfere with vigorous respiratory efforts. Other types of lung function tests are available for infants and unconscious persons.

Related tests

Spirometry can also be part of a bronchial challenge test
Bronchial challenge test

A bronchial challenge test is a medical test used to assist in the diagnosis of asthma. The patient breathes in nebulizer drug: either methacholine or histamine....
, used to determine bronchial hyperresponsiveness to either rigorous exercise, inhalation of cold/dry air, or with a pharmaceutical agent such as methacholine or histamine
Histamine

Histamine is a biogenic amine involved in local immune system as well as regulating physiological function in the gut and acting as a neurotransmitter....
.

Sometimes, to assess the reversibility of a particular condition, a bronchodilator
Bronchodilator

A bronchodilator is a substance that Wiktionary:dilate#Verb the Bronchus and bronchioles, decreasing airway resistance and thereby facilitating airflow....
 is administered before performing another round of tests for comparison. This is commonly referred to as a reversibility test, or a post bronchodilator test (Post BD), and is an important part in diagnosing asthma versus COPD.

Explanation of common test values in spirometric tests
AbbreviationNameDescription
FVCForced Vital Capacity
Vital capacity

Vital capacity is the maximum volume of air that a person can Exhalation after maximum inhalation.It can also be the maximum volume of air that a person can inhale after maximum exhalation....
This is the total amount of air that can forcibly be blown out after full inspiration, measured in liters.
FEV1Forced Expiratory Volume in 1 SecondThis is the amount of air that you can forcibly blow out in one second, measured in liters. Along with FVC it is considered one of the primary indicators of lung function.
FEV1/FVC FEV1% This is the ratio of FEV1 to FVC. In healthy adults this should be approximately 75–80%.
PEFPeak Expiratory FlowThis is the speed of the air moving out of your lungs at the beginning of the expiration, measured in liters per second.
FEF 25–75% or 25–50%Forced Expiratory Flow 25–75% or 25–50%This is the average flow (or speed) of air coming out of the lung during the middle portion of the expiration (also sometimes referred to as the MMEF, for maximal mid-expiratory flow).
FIF 25–75% or 25–50%Forced Inspiratory Flow 25–75% or 25–50%This is similar to FEF 25–75% or 25–50% except the measurement is taken during inspiration.
FETForced Expiratory TimeThis measures the length of the expiration in seconds.
SVCSlow Vital capacity
Vital capacity

Vital capacity is the maximum volume of air that a person can Exhalation after maximum inhalation.It can also be the maximum volume of air that a person can inhale after maximum exhalation....
 
TVTidal VolumeDuring the respiratory cycle, a specific volume of air is drawn into and then expired out of the lungs. This volume is tidal volume.
MVVMaximum Voluntary Ventilation A measure of the maximum amount of air that can be inhaled and exhaled in one minute, measured in liters/minute.


Note that functional residual capacity
Functional residual capacity

Functional Residual Capacity is the volume of air present in the lungs at the end of passive expiration. At FRC, the elastic recoil forces of the lungs and chest wall are equal but opposite and there is no exertion by the thoracic diaphragm or other respiratory muscles....
 (FRC) cannot be measured via spirometry, but it can be measured with a plethysmograph
Plethysmograph

A plethysmograph is an instrument for measuring changes in volume within an Organ or whole body ....
.

Results are usually given in both raw data (liters, liters per second) and percent predicted - the test result as a percent of the "predicted values" for the patients of similar characteristics (height, age, sex, and sometimes race and weight). The interpretation of the results can vary depending on the physician and the source of the predicted values. Generally speaking, results nearest to 100% predicted are the most normal, and results over 80% are often considered normal. However, review by a doctor is necessary for accurate diagnosis of any individual situation.

Technologies used in spirometers

  • Volumetric Spirometers
    • Water bell
    • Bellows
      Bellows

      A bellows is a device for delivering pressurized air in a controlled quantity to a controlled location. Basically, a bellows is a deformable container which has an outlet nozzle....
       wedge
  • Flow measuring Spirometers
    • Fleisch-pneumotach
    • Lilly (screen) pneumotach
    • Turbine
      Turbine

      A turbine is a rotary engine that extracts energy from a fluid flow. Claude Burdin coined the term from the Latin turbo, or vortex, during an 1828 engineering competition....
       (actually a rotating vane, this spins, the revolutions are counted as they break a light beam)
    • Pitot tube
      Pitot tube

      A Pitot tube is a pressure measurement instrument used to measure fluid flow velocity. The Pitot tube was invented by France engineer Henri Pitot in the early 1700s, and was modified to its modern form in the mid 1800s by French scientist Henry Darcy....
    • Hot-wire anemometer
      Anemometer

      An anemometer is a device that is used for measuring wind speed, and is one instrument used in a weather station. The term is derived from the Greek word anemos, meaning wind....
    • Ultrasound
      Ultrasound

      Ultrasound is cyclic sound pressure with a frequency greater than the upper limit of human hearing . Although this limit varies from person to person, it is approximately 20 Hertz in healthy, young adults and thus, 20 kHz serves as a useful lower limit in describing ultrasound....


See also


  • Peak flow meter
    Peak flow meter

    A peak flow meter is a small, hand-held device used to monitor a person's ability to breathe out air. It measures the airflow through the bronchus and thus the degree of obstruction in the airways....
  • Fowler method
    Fowler method

    Fowler's method, or the nitrogen washout method, is a way of measure dead space in the lung during a respiratory cycle. A subject takes a breath of 100% oxygen and exhales through a one-way valve measuring nitrogen content and volume....


External links



  • (ATS)
  • (ERS)