Selone
Encyclopedia
In chemistry, a selone is the structural analog of a ketone
where selenium
replaces oxygen
. Selones are used as chiral derivatizing agents for selenium-77 NMR spectroscopy. Chiral oxazolidineselones are excellent partners in the stereospecific aldol reaction
, and 77Se NMR can verify the enantiomeric purity
of the aldol product.
Ketone
In organic chemistry, a ketone is an organic compound with the structure RCR', where R and R' can be a variety of atoms and groups of atoms. It features a carbonyl group bonded to two other carbon atoms. Many ketones are known and many are of great importance in industry and in biology...
where selenium
Selenium
Selenium is a chemical element with atomic number 34, chemical symbol Se, and an atomic mass of 78.96. It is a nonmetal, whose properties are intermediate between those of adjacent chalcogen elements sulfur and tellurium...
replaces oxygen
Oxygen
Oxygen is the element with atomic number 8 and represented by the symbol O. Its name derives from the Greek roots ὀξύς and -γενής , because at the time of naming, it was mistakenly thought that all acids required oxygen in their composition...
. Selones are used as chiral derivatizing agents for selenium-77 NMR spectroscopy. Chiral oxazolidineselones are excellent partners in the stereospecific aldol reaction
Aldol reaction
The aldol reaction is a powerful means of forming carbon–carbon bonds in organic chemistry.Discovered independently by Charles-Adolphe Wurtz and Alexander Porfyrevich Borodin in 1872, the reaction combines two carbonyl compounds to form a new β-hydroxy carbonyl compound...
, and 77Se NMR can verify the enantiomeric purity
Enantiomeric excess
The enantiomeric excess of a substance is a measure of how pure it is. In this case, the impurity is the undesired enantiomer .-Definition:...
of the aldol product.