SIAH1
Encyclopedia
E3 ubiquitin-protein ligase SIAH1 is an enzyme
that in humans is encoded by the SIAH1 gene
.
with PEG10
, CACYBP
, POU2AF1
, RBBP8
, BAG1
, TRIB3
, NUMB
, KIF22
, KHDRBS3
, PEG3
and APC
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the SIAH1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
SIAH1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with PEG10
PEG10
Retrotransposon-derived protein PEG10 is a protein that in humans is encoded by the PEG10 gene.-Interactions:PEG10 has been shown to interact with SIAH2 and SIAH1.-Further reading:...
, CACYBP
CACYBP
Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene.-Interactions:CACYBP has been shown to interact with SKP1A and SIAH1.-Further reading:...
, POU2AF1
POU2AF1
POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene.-Interactions:POU2AF1 has been shown to interact with POU2F1 and SIAH1.-Further reading:...
, RBBP8
RBBP8
Retinoblastoma-binding protein 8 is a protein that in humans is encoded by the RBBP8 gene.-Interactions:RBBP8 has been shown to interact with LMO4, Retinoblastoma-like protein 2, Retinoblastoma-like protein 1, Ataxia telangiectasia mutated, Retinoblastoma protein, CTBP1, SIAH1 and BRCA1.-Further...
, BAG1
BAG1
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.BAG gene has been implicated in age related neurodegenerative diseases as Alzheimer's...
, TRIB3
TRIB3
Tribbles homolog 3 is a protein that in humans is encoded by the TRIB3 gene.-Interactions:TRIB3 has been shown to interact with CSNK2B, TIAF1, RELA, MCM3AP, ATF5, Granulin, ATF4, AKT1, Fibronectin and SIAH1.-Further reading:...
, NUMB
NUMB (gene)
Protein numb homolog is a protein that in humans is encoded by the NUMB gene.-Interactions:NUMB has been shown to interact with Adaptor-related protein complex 2, alpha 1, Mdm2, L1, DPYSL2, SIAH1, P53 and LNX1.-Further reading:...
, KIF22
KIF22
Kinesin-like protein KIF22 is a protein that in humans is encoded by the KIF22 gene.-Further reading:...
, KHDRBS3
KHDRBS3
KH domain-containing, RNA-binding, signal transduction-associated protein 3 is a protein that in humans is encoded by the KHDRBS3 gene.-Further reading:...
, PEG3
PEG3
Paternally-expressed gene 3 protein is a protein that in humans is encoded by the PEG3 gene.-Interactions:PEG3 has been shown to interact with SIAH2 and SIAH1.-Further reading:...
and APC
APC (gene)
Adenomatous polyposis coli also known as deleted in polyposis 2.5 is a protein that in humans is encoded by the APC gene. Mutations in the APC gene may result in colorectal cancer....
.