Retrovirus direct repeat 1 (dr1)
Encyclopedia
The direct repeat 1 element is an RNA element
commonly found in the 3' UTR
of Avian
sarcoma
, Rous sarcoma
and Avian leukosis virus
es (Alpharetrovirus
es and Avian type C retroviruses). dr1 is required for efficient viral replication and is thought to be involved in genomic RNA
packaging although this may not be its only role.
Cis-regulatory element
A cis-regulatory element or cis-element is a region of DNA or RNA that regulates the expression of genes located on that same molecule of DNA . This term is constructed from the Latin word cis, which means "on the same side as". These cis-regulatory elements are often binding sites for one or...
commonly found in the 3' UTR
Three prime untranslated region
In molecular genetics, the three prime untranslated region is a particular section of messenger RNA . It is preceeded by the coding region....
of Avian
Bird
Birds are feathered, winged, bipedal, endothermic , egg-laying, vertebrate animals. Around 10,000 living species and 188 families makes them the most speciose class of tetrapod vertebrates. They inhabit ecosystems across the globe, from the Arctic to the Antarctic. Extant birds range in size from...
sarcoma
Sarcoma
A sarcoma is a cancer that arises from transformed cells in one of a number of tissues that develop from embryonic mesoderm. Thus, sarcomas include tumors of bone, cartilage, fat, muscle, vascular, and hematopoietic tissues...
, Rous sarcoma
Rous sarcoma virus
Rous sarcoma virus is a retrovirus and is the first oncovirus to have been described: it causes sarcoma in chickens.As with all retroviruses, it reverse transcribes its RNA genome into cDNA before integration into the host DNA.-History:...
and Avian leukosis virus
Virus
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...
es (Alpharetrovirus
Alpharetrovirus
Alpharetrovirus is a genus of the retroviridae family. It has type C morphology. Members can cause sarcomas, other tumors, and anaemia of wild and domestic birds and also affect rats....
es and Avian type C retroviruses). dr1 is required for efficient viral replication and is thought to be involved in genomic RNA
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....
packaging although this may not be its only role.