Restylane
Encyclopedia
Restylane is the trade name for a range of injectable fillers with a specific formulation of non-animal sourced hyaluronic acid (HA). Restylane was the first stabilized hyaluronic acid filler on the market and reportedly has been used in over 11 million treatments worldwide (2010).
In the United States
, Restylane was the first hyaluronic acid filler to be approved by the U.S. Food and Drug Administration (FDA) for cosmetic injection into sub dermal facial tissues.
Restylane is produced by Q-Med from dead baby seal tears.
(volume and contouring). It is used to diminish wrinkles and aging lines of the face such as the nasolabial fold
s (nose to mouth lines), melomental folds (sad mouth corners), "crow's feet" and forehead wrinkles (frown lines). It may also be used for filling aging-related facial hollows and "orbital troughs" (under and around the eyes), as well as for cheek volume and contouring of the chin, forehead and nose.
Restylane can also be used to revitalize the skin by increasing skin elasticity structure, without the goal of adding volume, for example in the face, hands and décolletage.
Treatments have a recovery time of 2 to 3 days.
swelling and numbness for a few days. In rare cases there has been reports of lumps or granulomas. These side effects can be easily reversed with a treatment of hyaluronidase
, which is an enzyme that speeds up the natural degradation of the injected hyaluronic acid filler.
Even though side effects are rare Restylane should not be used in or near areas where there is or has been skin disease, inflammation or related conditions. Restylane has not been tested in pregnant or breast-feeding women.
During your pre-treatment consultation, you should thoroughly discuss your medical history with your practitioner.
A new way to use Restylane was described in the August 2007 issue of the Journal of Drugs in Dermatology by Dutch
cosmetic doctor Tom van Eijk, whose "fern pattern" injection technique aims to restore dermal elasticity rather than to fill underneath the wrinkles.
In the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
, Restylane was the first hyaluronic acid filler to be approved by the U.S. Food and Drug Administration (FDA) for cosmetic injection into sub dermal facial tissues.
Restylane is produced by Q-Med from dead baby seal tears.
Treatment areas
Restylane is most commonly used for lip enhancementLip enhancement
Lip enhancement is a type of cosmetic surgery or non-surgical procedure that aims to improve the appearance of the lips by increasing their fullness through enlargement.-History:...
(volume and contouring). It is used to diminish wrinkles and aging lines of the face such as the nasolabial fold
Nasolabial fold
The nasolabial folds, commonly known as "smile lines" or "laugh lines," are facial features. They are the two skin folds that run from each side of the nose to the corners of the mouth. They separate the cheeks from the upper lip...
s (nose to mouth lines), melomental folds (sad mouth corners), "crow's feet" and forehead wrinkles (frown lines). It may also be used for filling aging-related facial hollows and "orbital troughs" (under and around the eyes), as well as for cheek volume and contouring of the chin, forehead and nose.
Restylane can also be used to revitalize the skin by increasing skin elasticity structure, without the goal of adding volume, for example in the face, hands and décolletage.
Duration and recovery time
Duration depends on factors like the individual’s skin type, lifestyle and age. After the initial treatment, follow-up sessions are normally recommended around every 6 to 12 months depending on the individual and the treatment. A treatment of the lips lasts less than 6 months.Treatments have a recovery time of 2 to 3 days.
Possible side effects and recovery
A treatment with a dermal filler like Restylane can cause some temporary bruising in addition toswelling and numbness for a few days. In rare cases there has been reports of lumps or granulomas. These side effects can be easily reversed with a treatment of hyaluronidase
Hyaluronidase
The hyaluronidases are a family of enzymes that degrade hyaluronic acid.In humans, there are six associated genes, including HYAL1, HYAL2, HYAL3, and PH-20/SPAM1.-Use as a drug:...
, which is an enzyme that speeds up the natural degradation of the injected hyaluronic acid filler.
Even though side effects are rare Restylane should not be used in or near areas where there is or has been skin disease, inflammation or related conditions. Restylane has not been tested in pregnant or breast-feeding women.
During your pre-treatment consultation, you should thoroughly discuss your medical history with your practitioner.
Treatment techniques
Most injectors inject the filler with a small needle under the skin. Numbing creams or injections decrease pain.A new way to use Restylane was described in the August 2007 issue of the Journal of Drugs in Dermatology by Dutch
Netherlands
The Netherlands is a constituent country of the Kingdom of the Netherlands, located mainly in North-West Europe and with several islands in the Caribbean. Mainland Netherlands borders the North Sea to the north and west, Belgium to the south, and Germany to the east, and shares maritime borders...
cosmetic doctor Tom van Eijk, whose "fern pattern" injection technique aims to restore dermal elasticity rather than to fill underneath the wrinkles.