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Plant virus

Plant virus

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Plant viruses are virus
Virus
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...

es that affect plants. Like all other viruses, plant viruses are obligate intracellular parasites that do not have the molecular machinery to replicate
Self-replication
Self-replication is any behavior of a dynamical system that yields construction of an identical copy of that dynamical system. Biological cells, given suitable environments, reproduce by cell division. During cell division, DNA is replicated and can be transmitted to offspring during reproduction...

 without a host
Host (biology)
In biology, a host is an organism that harbors a parasite, or a mutual or commensal symbiont, typically providing nourishment and shelter. In botany, a host plant is one that supplies food resources and substrate for certain insects or other fauna...

. Plant viruses are pathogen
Pathogen
A pathogen gignomai "I give birth to") or infectious agent — colloquially, a germ — is a microbe or microorganism such as a virus, bacterium, prion, or fungus that causes disease in its animal or plant host...

ic to higher plants. While this article does not intend to list all plant viruses, it discusses some important viruses as well as their uses in plant molecular biology
Molecular biology
Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry...

.

Overview


Although plant viruses are not nearly as well understood as the animal counterparts, one plant virus has become iconic. The first virus to be discovered (see below) was Tobacco mosaic virus
Tobacco mosaic virus
Tobacco mosaic virus is a positive-sense single stranded RNA virus that infects plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns on the leaves . TMV was the first virus to be discovered...

(TMV). This and other viruses cause an estimated US$60 billion loss in crop yields worldwide each year. Plant viruses are grouped into 73 genera and 49 families
Family (biology)
In biological classification, family is* a taxonomic rank. Other well-known ranks are life, domain, kingdom, phylum, class, order, genus, and species, with family fitting between order and genus. As for the other well-known ranks, there is the option of an immediately lower rank, indicated by the...

.

To transmit from one plant to another and from one plant cell to another, plant viruses must use strategies that are usually different from animal viruses. Plants do not move, and so plant-to-plant transmission usually involves vectors (such as insects). Plant cells are surrounded by solid cell wall
Cell wall
The cell wall is the tough, usually flexible but sometimes fairly rigid layer that surrounds some types of cells. It is located outside the cell membrane and provides these cells with structural support and protection, and also acts as a filtering mechanism. A major function of the cell wall is to...

s, therefore transport through plasmodesmata
Plasmodesmata
Plasmodesmata are microscopic channels which traverse the cell walls of plant cells and some algal cells, enabling transport and communication between them. Species that have plasmodesmata include members of the Charophyceae, Charales and Coleochaetales , as well as all embryophytes, better known...

 is the preferred path for virions to move between plant cells. Plants probably have specialized mechanisms for transporting mRNAs through plasmodesmata, and these mechanisms are thought to be used by RNA virus
RNA virus
An RNA virus is a virus that has RNA as its genetic material. This nucleic acid is usually single-stranded RNA but may be double-stranded RNA...

es to spread from one cell to another.

Plant defenses against viral infection include, among other measures, the use of siRNA
Sírna
Sírna Sáeglach , son of Dian mac Demal, son of Demal mac Rothechtaid, son of Rothechtaid mac Main, was, according to medieval Irish legend and historical tradition, a High King of Ireland...

 in response to dsRNA. Most plant viruses encode a protein to suppress this response. Plants also reduce transport through plasmodesmata
Plasmodesmata
Plasmodesmata are microscopic channels which traverse the cell walls of plant cells and some algal cells, enabling transport and communication between them. Species that have plasmodesmata include members of the Charophyceae, Charales and Coleochaetales , as well as all embryophytes, better known...

 in response to injury.

History


The discovery of plant viruses causing disease
Disease
A disease is an abnormal condition affecting the body of an organism. It is often construed to be a medical condition associated with specific symptoms and signs. It may be caused by external factors, such as infectious disease, or it may be caused by internal dysfunctions, such as autoimmune...

 is often accredited to Martinus Beijerinck
Martinus Beijerinck
Martinus Willem Beijerinck was a Dutch microbiologist and botanist. Born in Amsterdam, Beijerinck studied at the Technical School of Delft, where he was awarded the degree of Chemical Engineer in 1872. He obtained his Doctor of Science degree from the University of Leiden in 1877...

 who determined, in 1898, that plant sap obtained from tobacco leaves with the "mosaic disease" remained infectious when passed through a porcelain filter. This was in contrast to bacteria microorganisms, which were retained by the filter. Beijerinck referred to the infectious filtrate as a "contagium vivum fluidum", thus the coinage of the modern term "virus".

After the initial discovery of the ‘viral concept’ there was need to classify any other known viral
Virus
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...

 diseases based on the mode of transmission even though microscopic
Microscopic
The microscopic scale is the scale of size or length used to describe objects smaller than those that can easily be seen by the naked eye and which require a lens or microscope to see them clearly.-History:...

 observation proved fruitless. In 1939 Holmes published a classification list of 129 plant viruses. This was expanded and in 1999 there were 977 officially recognized, and some provisional, plant virus species.

The purification (crystallization) of TMV was first performed by Wendell Stanley, who published his findings in 1935, although he did not determine that the RNA was the infectious material. However, he received the Nobel Prize
Nobel Prize
The Nobel Prizes are annual international awards bestowed by Scandinavian committees in recognition of cultural and scientific advances. The will of the Swedish chemist Alfred Nobel, the inventor of dynamite, established the prizes in 1895...

 in Chemistry in 1946. In the 1950s a discovery by two labs simultaneously proved that the purified RNA
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....

 of the TMV was infectious which reinforced the argument. The RNA carries genetic
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....

 information to code for the production of new infectious particles.

More recently virus research has been focused on understanding the genetics and molecular biology of plant virus genomes, with a particular interest in determining how the virus can replicate, move and infect plants. Understanding the virus genetics and protein functions has been used to explore the potential for commercial use by biotechnology
Biotechnology
Biotechnology is a field of applied biology that involves the use of living organisms and bioprocesses in engineering, technology, medicine and other fields requiring bioproducts. Biotechnology also utilizes these products for manufacturing purpose...

 companies. In particular, viral-derived sequences have been used to provide an understanding of novel forms of resistance
Plant disease resistance
Plant disease resistance is crucial to the reliable production of food, and it provides significant reductions in agricultural use of fuel, land, water and other inputs. There are numerous examples of devastating plant disease impacts , as well as recurrent severe plant disease issues...

. The recent boom in technology allowing humans to manipulate plant viruses may provide new strategies for production of value-added proteins in plants.

Structure


Viruses are extremely small and can only be observed with an electron microscope
Electron microscope
An electron microscope is a type of microscope that uses a beam of electrons to illuminate the specimen and produce a magnified image. Electron microscopes have a greater resolving power than a light-powered optical microscope, because electrons have wavelengths about 100,000 times shorter than...

. The structure of a virus is given by its coat of proteins, which surround the viral genome
Genome
In modern molecular biology and genetics, the genome is the entirety of an organism's hereditary information. It is encoded either in DNA or, for many types of virus, in RNA. The genome includes both the genes and the non-coding sequences of the DNA/RNA....

. Assembly of viral particles takes place spontaneously.

Over 50% of known plant viruses are rod-shaped (flexuous or rigid). The length of the particle is normally dependent on the genome but it is usually between 300–500 nm with a diameter
Diameter
In geometry, a diameter of a circle is any straight line segment that passes through the center of the circle and whose endpoints are on the circle. The diameters are the longest chords of the circle...

 of 15–20 nm. Protein subunits can be placed around the circumference
Circumference
The circumference is the distance around a closed curve. Circumference is a special perimeter.-Circumference of a circle:The circumference of a circle is the length around it....

 of a circle to form a disc. In the presence of the viral genome, the discs are stacked, then a tube is created with room for the nucleic acid
Nucleic acid
Nucleic acids are biological molecules essential for life, and include DNA and RNA . Together with proteins, nucleic acids make up the most important macromolecules; each is found in abundance in all living things, where they function in encoding, transmitting and expressing genetic information...

 genome in the middle.

The second most common structure amongst plant viruses are isometric
Isometric
The term isometric comes from the Greek for "having equal measurement".isometric may mean:* Isometric projection , a method for the visual representation of three-dimensional objects in two dimensions; a form of orthographic projection, or more specifically, an axonometric projection.* Isometry and...

 particles. They are 40–50 nm in diameter. In cases when there is only a single coat protein, the basic structure consists of 60 T subunits, where T is an integer
Integer
The integers are formed by the natural numbers together with the negatives of the non-zero natural numbers .They are known as Positive and Negative Integers respectively...

. Some viruses may have 2 coat proteins are the associate to form an icosahedral
Icosahedron
In geometry, an icosahedron is a regular polyhedron with 20 identical equilateral triangular faces, 30 edges and 12 vertices. It is one of the five Platonic solids....

 shaped particle.

There are three genera of Geminiviridae
Geminiviridae
Geminiviruses are plant viruses which have single-stranded circular DNA genomes encoding genes that diverge in both directions from a virion strand origin of replication . According to the Baltimore classification they are considered class II viruses...

that possess geminate particles which are like two isometric
Isometric
The term isometric comes from the Greek for "having equal measurement".isometric may mean:* Isometric projection , a method for the visual representation of three-dimensional objects in two dimensions; a form of orthographic projection, or more specifically, an axonometric projection.* Isometry and...

 particles stuck together.

A very small number of plant viruses have, in addition to their coat proteins, a lipid envelope
Cell membrane
The cell membrane or plasma membrane is a biological membrane that separates the interior of all cells from the outside environment. The cell membrane is selectively permeable to ions and organic molecules and controls the movement of substances in and out of cells. It basically protects the cell...

. This is derived from the plant cell membrane as the virus particle buds
Viral shedding
Viral shedding refers to the successful reproduction, expulsion, and host-cell infection caused by virus progeny. Once replication has been completed and the host cell is exhausted of all resources in making viral progeny, the viruses may begin to leave the cell by several methods.The term is used...

 off from the cell
Cell (biology)
The cell is the basic structural and functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos....

.

Through sap


Viruses can be spread by direct transfer of sap by contact of a wounded plant with a healthy one. Such contact may occur during agricultural practices, as by damage caused by tools or hands, or naturally, as by an animal feeding on the plant. Generally TMV, potato viruses and cucumber mosaic viruses are transmitted via sap.

Insects


Plant viruses need to be transmitted by a vector, most often insects such as leafhoppers. One class of viruses, the Rhabdoviridae
Rhabdoviridae
Rhabdoviruses are viruses belonging to the family Rhabdoviridae, which is in the order Mononegavirales. The name is derived from the Greek rhabdos meaning rod referring to the shape of the viral particles. Rhabdoviruses infect a broad range of hosts throughout the animal and plant kingdoms...

, has been proposed to actually be insect viruses that have evolved to replicate
Replicate
Replicate may refer to:* In biology, replication is a process by which genetic material, a cell, or an organism reproduces or makes an exact copy or copies...

 in plants. The chosen insect vector of a plant virus will often be the determining factor in that virus's host range: it can only infect plants that the insect vector feeds upon. This was shown in part when the old world
Old World
The Old World consists of those parts of the world known to classical antiquity and the European Middle Ages. It is used in the context of, and contrast with, the "New World" ....

 white fly made it to the USA, where it transferred many plant viruses into new hosts.Depending on the way they are transmitted, plant viruses are classified as non-persistent, semi-persistent and persistent. In non-persistent transmission, viruses become attached to the distal tip of the stylet
Stylet
A stylet is a hard, sharp, anatomical structure found in some invertebrates.For example, the word stylet or stomatostyle, is used for the primitive piercing mouthparts of some nematodes and some nemerteans...

 of the insect and on the next plant it feeds on, it inoculates it with the virus. Semi-persistent viral transmission involves the virus entering the foregut
Foregut
The foregut is the anterior part of the alimentary canal, from the mouth to the duodenum at the entrance of the bile duct. At this point it is continuous with the midgut...

 of the insect. Those viruses that manage to pass through the gut into the haemolymph and then to the salivary glands are known as persistent
Persistent
Persistent may refer to:* Persistent Systems, a technology company* USS Persistent, three United States Navy ships...

. There are two sub-classes of persistent viruses: propagative and circulative. Propagative viruses are able to replicate in both the plant and the insect (and may have originally been insect viruses), whereas circulative can not. Circulative viruses are protected inside aphids by the chaperone protein symbionin produced by bacterial symbionts.Many plant viruses encode within their genome polypeptides with domains essential for transmission by insects. In non-persistent and semi-persistent viruses, these domains are in the coat protein and another protein known as the helper component. A bridging hypothesis
Hypothesis
A hypothesis is a proposed explanation for a phenomenon. The term derives from the Greek, ὑποτιθέναι – hypotithenai meaning "to put under" or "to suppose". For a hypothesis to be put forward as a scientific hypothesis, the scientific method requires that one can test it...

 has been proposed to explain how these proteins aid in insect-mediated viral transmission. The helper component will bind to the specific domain of the coat protein, and then the insect mouthparts — creating a bridge. In persistent propagative viruses, such as tomato spotted wilt virus (TSWV), there is often a lipid coat surrounding the proteins that is not seen in the other classes of plant viruses. In the case of TSWV, 2 viral proteins are expressed in this lipid envelope. It has been proposed that the viruses bind via these proteins and are then taken into the insect cell
Cell (biology)
The cell is the basic structural and functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos....

 by receptor-mediated endocytosis
Endocytosis
Endocytosis is a process by which cells absorb molecules by engulfing them. It is used by all cells of the body because most substances important to them are large polar molecules that cannot pass through the hydrophobic plasma or cell membrane...

.

Nematodes


Soil-borne nematode
Nematode
The nematodes or roundworms are the most diverse phylum of pseudocoelomates, and one of the most diverse of all animals. Nematode species are very difficult to distinguish; over 28,000 have been described, of which over 16,000 are parasitic. It has been estimated that the total number of nematode...

s also have been shown to transmit viruses. They acquire and transmit them by feeding on infected root
Root
In vascular plants, the root is the organ of a plant that typically lies below the surface of the soil. This is not always the case, however, since a root can also be aerial or aerating . Furthermore, a stem normally occurring below ground is not exceptional either...

s. Viruses can be transmitted both non-persistently and persistently, but there is no evidence of viruses being able to replicate in nematodes. The virions attach to the stylet (feeding organ) or to the gut when they feed on an infected plant and can then unattach during later feeding to infect other plants. Examples of viruses that can be transmitted by nematodes include tobacco ringspot virus
Tobacco ringspot virus
Tobacco ringspot virus is a plant pathogenic virus in the plant virus family Comoviridae. It is the type species of the Comoviridae Genus Nepovirus. Nepoviruses are be transmitted between plants by nematodes...

 and tobacco rattle virus
Tobacco rattle virus
Tobacco rattle virus is a plant pathogenic virus.-External links:**...

.

Plasmodiophorids


A number of virus genera are transmitted, both persistently and non-persistently, by soil borne zoosporic
Zoospore
A zoospore is a motile asexual spore that uses a flagellum for locomotion. Also called a swarm spore, these spores are created by some algae, bacteria and fungi to propagate themselves.-Flagella:...

 protozoa
Protozoa
Protozoa are a diverse group of single-cells eukaryotic organisms, many of which are motile. Throughout history, protozoa have been defined as single-cell protists with animal-like behavior, e.g., movement...

. These protozoa are not phytopathogenic themselves, but parasitic. Transmission of the virus takes place when they become associated with the plant roots. Examples include Polymyxa graminis
Polymyxa graminis
Polymyxa graminis is a species of plasmodiophorid protist. It is an obligate parasite of plant roots and though itself in non-pathogenic, it is responsible for the transmission of several very important plant viruses, including barley yellow mosaic virus and soil-borne wheat mosaic virus...

, which has been shown to transmit plant viral diseases in cereal crops and Polymyxa betae which transmits Beet necrotic yellow vein virus
Beet necrotic yellow vein virus
Beet necrotic yellow vein virus is a plant virus, transmitted by the protozoan Polymyxa betae ). Polymyxa forms highly resistant spores that can rest in soils for more than two decades...

. Plasmodiophorids also create wounds in the plant's root through which other viruses can enter.

Seed and pollen borne viruses


Plant virus transmission from generation to generation occurs in about 20% of plant viruses. When viruses are transmitted by seeds, the seed is infected in the generative cells and the virus is maintained in the germ cells and sometimes, but less often, in the seed coat. When the growth and development of plants is delayed because of situations like unfavourable weather, there is an increase in the amount of virus infections in seeds. There does not seem to be a correlation between the location of the seed on the plant and its chances of being infected. [5] Little is known about the mechanisms involved in the transmission of plant viruses via seeds, although it is known that it is environmentally influenced and that seed transmission occurs because of a direct invasion of the embryo via the ovule or by an indirect route with an attack on the embryo mediated by infected gametes. [5] [6] These processes can occur concurrently or separately depending on the host plant. It is unknown how the virus is able to directly invade and cross the embryo and boundary between the parental and progeny generations in the ovule. [6]
Many plants species can be infected through seeds including but not limited to the families Leguminosae, Solanaceae
Solanaceae
Solanaceae are a family of flowering plants that include a number of important agricultural crops as well as many toxic plants. The name of the family comes from the Latin Solanum "the nightshade plant", but the further etymology of that word is unclear...

, Compositae, Rosaceae
Rosaceae
Rosaceae are a medium-sized family of flowering plants, including about 2830 species in 95 genera. The name is derived from the type genus Rosa. Among the largest genera are Alchemilla , Sorbus , Crataegus , Cotoneaster , and Rubus...

, Curcurbitaceae, Gramineae. [5]

Direct plant-to-human transmission


Researchers from the University of the Mediterranean in Marseille, France have found evidence that suggest a virus common to peppers, the Pepper Mild Mottle Virus
Pepper mild mottle virus
Pepper mild mottle virus ' is a plant pathogenic virus that belongs to the plant virus genus, Tobamovirus. Like other viruses in this genus, it has rod-shaped particles and is easily transmitted by mechanical inoculation. It can also be transmitted by contaminated seeds. No insect vector is known....

 (PMMoV) may have moved on to infect humans. This is a very rare and highly unlikely event as, to enter a cell and replicate, a virus must "bind to a receptor on its surface, and a plant virus would be highly unlikely to recognize a receptor on a human cell. One possibility is that the virus does not infect human cells directly. Instead, the naked viral RNA may alter the function of the cells through a mechanism similar to RNA interference, in which the presence of certain RNA sequences can turn genes on and off," according to Virologist Robert Garry from the Tulane University in New Orleans, Louisiana.

Symptoms include being more likely to have fever, abdominal pain, and itching.

Translation of plant viral proteins


75% of plant viruses have genomes that consist of single stranded RNA (ssRNA). 65% of plant viruses have +ssRNA, meaning that they are in the same sense orientation as messenger RNA
Messenger RNA
Messenger RNA is a molecule of RNA encoding a chemical "blueprint" for a protein product. mRNA is transcribed from a DNA template, and carries coding information to the sites of protein synthesis: the ribosomes. Here, the nucleic acid polymer is translated into a polymer of amino acids: a protein...

 but 10% have -ssRNA, meaning they must be converted to +ssRNA before they can be translated. 5% are double stranded RNA and so can be immediately translated as +ssRNA viruses. 3% require a reverse transcriptase
Reverse transcriptase
In the fields of molecular biology and biochemistry, a reverse transcriptase, also known as RNA-dependent DNA polymerase, is a DNA polymerase enzyme that transcribes single-stranded RNA into single-stranded DNA. It also helps in the formation of a double helix DNA once the RNA has been reverse...

 enzyme to convert between RNA and DNA. 17% of plant viruses are ssDNA and very few are dsDNA, in contrast a quarter of animal viruses are dsDNA and three quarters of bacteriophage
Bacteriophage
A bacteriophage is any one of a number of viruses that infect bacteria. They do this by injecting genetic material, which they carry enclosed in an outer protein capsid...

 are dsDNA. Viruses use the plant ribosomes to produce the 4-10 proteins encoded by their genome. However, since all of the proteins are encoded on a single strand (that is, they are polycistronic) this will mean that the ribosome will either only produce one protein, as it will terminate translation at the first stop codon
Stop codon
In the genetic code, a stop codon is a nucleotide triplet within messenger RNA that signals a termination of translation. Proteins are based on polypeptides, which are unique sequences of amino acids. Most codons in messenger RNA correspond to the addition of an amino acid to a growing polypeptide...

, or that a polyprotein will be produced. Plant viruses have had to evolve special techniques to allow the production of viral proteins by plant cell
Plant cell
Plant cells are eukaryotic cells that differ in several key respects from the cells of other eukaryotic organisms. Their distinctive features include:...

s.

5' Cap


For translation
Translation
Translation is the communication of the meaning of a source-language text by means of an equivalent target-language text. Whereas interpreting undoubtedly antedates writing, translation began only after the appearance of written literature; there exist partial translations of the Sumerian Epic of...

 to occur, eukaryotic mRNAs require a 5' Cap
5' cap
The 5' cap is a specially altered nucleotide on the 5' end of precursor messenger RNA and some other primary RNA transcripts as found in eukaryotes. The process of 5' capping is vital to creating mature messenger RNA, which is then able to undergo translation...

 structure. This means that viruses must also have one. This normally consists of 7MeGpppN where N is normally adenine
Adenine
Adenine is a nucleobase with a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate and the cofactors nicotinamide adenine dinucleotide and flavin adenine dinucleotide , and protein synthesis, as a chemical component of DNA...

 or guanine
Guanine
Guanine is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine . In DNA, guanine is paired with cytosine. With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with...

. The viruses encode a protein, normally a replicase, with a methyltransferase
Methyltransferase
A methyltransferase is a type of transferase enzyme that transfers a methyl group from a donor to an acceptor.Methylation often occurs on nucleic bases in DNA or amino acids in protein structures...

 activity to allow this.

Some viruses are cap-snatchers. During this process, a 7mG-capped host mRNA is recruited by the viral transcriptase complex and subsequently cleaved by a virally encoded endonuclease. The resulting capped leader RNA is used to prime transcription on the viral genome.

However some plant viruses do not use cap, yet translate efficiently due to cap-independent translation enhancers present in 5' and 3' untranslated regions of viral mRNA.

Readthrough


Some viruses (e.g. tobacco mosaic virus
Tobacco mosaic virus
Tobacco mosaic virus is a positive-sense single stranded RNA virus that infects plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns on the leaves . TMV was the first virus to be discovered...

 (TMV)) have RNA sequences that contain a "leaky" stop codon. In TMV 95% of the time the host ribosome will terminate the synthesis of the polypeptide at this codon but the rest of the time it continues past it. This means that 5% of the proteins produced are larger than and different from the others normally produced, which can be thought of as a crude form of transcriptional regulation
Transcriptional regulation
Transcriptional regulation is the change in gene expression levels by altering transcription rates. -Regulation of transcription:Regulation of transcription controls when transcription occurs and how much RNA is created...

. In TMV, this extra sequence of polypeptide is an RNA polymerase
RNA polymerase
RNA polymerase is an enzyme that produces RNA. In cells, RNAP is needed for constructing RNA chains from DNA genes as templates, a process called transcription. RNA polymerase enzymes are essential to life and are found in all organisms and many viruses...

 that replicates its genome.

Production of sub-genomic RNAs


Some viruses use the production of subgenomic RNAs to ensure the translation of all proteins within their genomes. In this process the first protein encoded on the genome, and this the first to be translated, is a replicase. This protein will act on the rest of the genome producing negative strand sub-genomic RNAs then act upon these to form positive strand sub-genomic RNAs that are essentially mRNAs ready for translation.

Segmented genomes


Some viral families, such as the Bromoviridae
Bromoviridae
The Bromoviridae are a family of plant viruses, including the following genera:*Genus Alfamovirus; type species: Alfalfa mosaic virus*Genus Anulavirus; type species: Pelargonium zonate spot virus...

instead opt to have multi-partite genomes, genomes split between multiple viral particles. For infection to occur, the plant must be infected with all particles across the genome. For instance Brome mosaic virus
Brome mosaic virus
Brome mosaic virus is a small , positive-stranded, icosahedral RNA plant virus belonging to the family Bromoviridae of the alphavirus-like superfamily....

has a genome split between 3 viral particles, and all 3 particles with the different RNAs are required for infection
Infection
An infection is the colonization of a host organism by parasite species. Infecting parasites seek to use the host's resources to reproduce, often resulting in disease...

 to take place.

Polyprotein processing


This strategy is adopted by viral genera such as the Potyviridae
Potyviridae
The Potyviridae are a family of plant viruses. They are . Their genome is composed of positive-sense RNA which is surrounded by a protein coat made up of a single viral encoded protein called a capsid. All induce the formation of virus inclusion bodies called in their hosts...

 and Tymovirus. The ribosome translates a single protein from the viral genome. Within the polyprotein is an enzyme (or enzymes) with proteinase function that is able to cleave the polyprotein into the various single proteins or just cleave away the protease, which can then cleave other polypeptides producing the mature proteins.

Well understood plant viruses


Tobacco mosaic virus
Tobacco mosaic virus
Tobacco mosaic virus is a positive-sense single stranded RNA virus that infects plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns on the leaves . TMV was the first virus to be discovered...

 (TMV) and Cauliflower mosaic virus
Cauliflower mosaic virus
Cauliflower mosaic virus is the type member of the caulimoviruses, one of the six genera in the Caulimoviridae family, pararetroviruses that infect plants...

 (CaMV) are frequently used in plant molecular biology. Of special interest is the CaMV 35S promoter, which is a very strong promoter most frequently used in plant transformation
Transformation (genetics)
In molecular biology transformation is the genetic alteration of a cell resulting from the direct uptake, incorporation and expression of exogenous genetic material from its surroundings and taken up through the cell membrane. Transformation occurs naturally in some species of bacteria, but it can...

s.

See also

  • Virus
    Virus
    A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...

  • Aphididae
    Aphididae
    Aphididae is a very large insect family in the aphid superfamily , of the order Hemiptera. There are several thousand species in this family, many of which are well known for being serious plant pests...

  • Electrical penetration graph
    Electrical penetration graph
    The electrical penetration graph or EPG is a system used by biologists to study the interaction of insects such as aphids, thrips, and leafhoppers with plants. Therefore, it can also be used to study the basis of plant virus transmission, host plant selection by insects and the way in which insects...

  • Subgenomic
  • Host defense in plants

Further reading

  • Zaitlin, Milton and Peter Palukaitis (2000), Advances in Understanding Plant Viruses and Virus Diseases. Vol. 38: 117–143 (doi:10.1146/annurev.phyto.38.1.117)
  • Zaitlin, Milton (1998), Discoveries in Plant Biology, New York 14853, USA. Pp. 105–110. S. D. Kung and S. F. Yang (eds).
  • Dickinson, M. (2003), Molecular Plant Pathology. BIOS Scientific Publishers
    BIOS Scientific Publishers
    BIOS Scientific Publishers was an English publisher. The main offices were based at Milton Park near Abingdon, Oxfordshire, south of Oxford, England. The company specialised in biosciences....

    .
  • http://stinet.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=Plant
  • Wang, Daowen and Andrew J. Maule (June 1994), "A Model for Seed Transmission of a Plant Virus: Genetic and Structural Analyses of Pea Embryo Invasion by Pea Seed-Borne Mosaic Virus" The Plant Cell, Vol 6, 777–787.
  • http://www.plantcell.org/cgi/reprint/6/6/777

External links