National Disease Research Interchange
Encyclopedia
The National Disease Research Interchange (NDRI) is an American 501(c)(3) non-profit organization
Non-profit organization
Nonprofit organization is neither a legal nor technical definition but generally refers to an organization that uses surplus revenues to achieve its goals, rather than distributing them as profit or dividends...

 founded in 1980 to provide donated human cells, tissue and organs to researchers. It is based in Philadelphia, Pennsylvania
Pennsylvania
The Commonwealth of Pennsylvania is a U.S. state that is located in the Northeastern and Mid-Atlantic regions of the United States. The state borders Delaware and Maryland to the south, West Virginia to the southwest, Ohio to the west, New York and Ontario, Canada, to the north, and New Jersey to...

.

NDRI's objective is to make it easy for researchers to get the human tissues and organs they need, prepared, preserved and shipped according to their scientific protocols, as quickly as possible, and in the largest available quantities.

Biospecimen provisioning and storage

The vast majority of the biospecimens supplied by NDRI are matched according to researcher-specified protocols and sent directly to the investigator. These include samples shipped at 4ºC immediately after procurement, as well as snap-frozen, fixed and paraffin and OCT-embedded materials.

The Online Biospecimen Catalogue (OBC) is an additional resource offered by NDRI that allows approved researchers to select from a variety of banked human organ and tissue samples from all body systems. Tissues and organs offered via the OBC represent a small percentage of material supplied to the research community by NDRI every year, and not all materials are listed in it.

Biospecimens are stored at -82 degrees Celsius in a freezer room housing fourteen tissue freezers and liquid nitrogen storage tanks.

Funding

The National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...

 (NIH) have provided grants to NDRI since 1984. Current support for NDRI comes from several institutes within the NIH, including funding from the National Center for Research Resources
National Center for Research Resources
The National Center for Research Resources or NCRR, is a United States government agency. NCRR provides funding to laboratory scientists and researchers for facilities and tools in the goal of curing and treating diseases.-Organization and history:...

, the National Eye Institute
National Eye Institute
The National Eye Institute is one of the US National Institutes of Health that was established in 1968. The mission of NEI is to prolong and protect the vision of the American people. The NEI conducts and performs research into treating and preventing diseases affecting the eye or vision....

, the National Institute for Diabetes and Digestive and Kidney Diseases, the National Institute of Allergy and Infectious Diseases
National Institute of Allergy and Infectious Diseases
The National Institute of Allergy and Infectious Diseases is one of the 27 institutes and centers that make up the National Institutes of Health , an agency of the United States Department of Health and Human Services...

, the National Institute of Arthritis and Musculoskeletal and Skin Diseases
National Institute of Arthritis and Musculoskeletal and Skin Diseases
The National Institute of Arthritis and Musculoskeletal and Skin Diseases, or NIAMS, is an institute of the National Institutes of Health, an agency of the United States Department of Health and Human Services...

, the National Heart, Lung and Blood Institute, and the Office of Rare Diseases Research. Additional support comes from voluntary health organizations and from corporate and individual donors.

External links

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