Nafcillin

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Nafcillin

Nafcillin sodium is a narrow spectrum beta-lactam antibiotic

Beta-lactam antibiotic

?-lactam antibiotics are a broad class of antibiotics that include penicillin derivatives, cephalosporins, monobactams, carbapenems, and Beta-lactamase inhibitors, that is, any antibiotic agent that contains a beta-lactam nucleus in its molecular structure....
of the penicillin

Penicillin

Penicillin is a group of antibiotics derived from Penicillium fungi. They are Beta-lactam antibiotics used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms....
class.

There is evidence that it induces cytochrome P-450 enzymes.

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Encyclopedia

Nafcillin sodium is a narrow spectrum beta-lactam antibiotic

Beta-lactam antibiotic

Penicillin

Uses

As a beta-lactamase

Beta-lactamase

Beta-lactamases are enzymes produced by some bacteria and are responsible for their antibiotic resistance to beta-lactam antibiotics like penicillins, cephalosporins , cephamycins, and carbapenems ....
-resistant penicillin, it is used to treat infections caused by Gram-positive

Gram-positive

Gram-positive Bacteria are those that are stained dark blue or violet by Gram staining. This is in contrast to Gram-negative bacteria, which cannot retain the crystal violet stain, instead taking up the counterstain and appearing red or pink....
bacteria

Bacteria

The Bacteria are a large group of unicellular microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals....
, particularly species

Species

In biology, a species is one of the basic units of biological classification and a taxonomic rank. A species is often defined as a group of organisms capable of interbreeding and producing fertile offspring....
of Staphylococci, that are resistant

Antibiotic resistance

Antibiotic resistance is the ability of a microorganism to withstand the effects of antibiotics. It is a specific type of drug resistance. Antibiotic resistance evolves via natural selection acting upon random mutation, but it can also be engineered by applying an evolutionary stress on a population....
to other penicillins.

Side effects

As with all penicillins, serious life-threatening allergic reactions

Allergy

Allergy is a Disorder of the immune system often also referred to as atopy. Allergic reactions occur to Natural environmental substances known as allergens; these reactions are Acquired disorder, predictable and rapid....
can occur.

Milder side effects include:

Nausea
Nausea

Nausea is the sensation of unease and discomfort in the stomach with an urge to vomit....
and vomiting
Vomiting

Vomiting is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Undesired vomiting may result from many causes, ranging from gastritis or poisoning to brain tumors, or elevated intracranial pressure....
Diarrhea
Diarrhea

In medicine, diarrhea, also spelled diarrhoea , is characterized by frequent loose or liquid bowel movements. The spelling of "diarrhea" is an appropriation of the Greek "diarrhoia" meaning "a flowing through." ....
, often due to suppression of normal gastrointestinal bacteria. Occasionally, this leads to a more serious super-infection with an organism like Clostridium difficile
Clostridium difficile

Clostridium difficile , also known as "CDF/cdf", or "C. diff", is a species of Gram-positive bacteria of the genus Clostridium. Clostridia are Anaerobic organism, endospore-forming rods ....
Abdominal pain
Abdominal pain

Abdominal pain can be one of the symptoms associated with transient disorders or serious disease. Making a definitive diagnosis of the cause of abdominal pain can be difficult, because many diseases can result in this symptom....
Yeast
Yeast

Yeasts are eukaryote microorganisms classified in the Kingdom fungus, with about 1,500 species currently described; they dominate fungal diversity in the oceans....
infections (thrush
Candidiasis

Candidiasis, commonly called yeast infection or thrush, is a fungal infection of any of the Candida species, of which Candida albicans is the most common....
) affecting the mouth
Mouth

The mouth, buccal cavity, or oral cavity is the first portion of the alimentary canal that receives food and begins digestion by mechanically breaking up the solid food particles into smaller pieces and mixing them with saliva....
and tongue
Tongue

The tongue is skeletal muscle on the floor of the mouth that manipulates food for chewing . It is the primary organ of taste. Much of the upper surface of the tongue is covered in papillae and taste buds....
or vagina
Vagina

The vagina is a fibromuscular cylinder tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles....