Khorlo means: 'wheel

Wheel

A wheel is a device that allows heavy objects to be moved easily through rotating on an axle through its center, facilitating movement or transportation while supporting a load, or performing labor in machines. Common examples found in transport applications. A wheel, together with an axle,...

', 'round', 'mandala', 'chakra', 'samsara'. Khorlo is the lexical item commonly used to denote 'chakra

Chakra

Chakra is a concept originating in Hindu texts, featured in tantric and yogic traditions of Hinduism and Buddhism. Its name derives from the Sanskrit word for "wheel" or "turning" .Chakra is a concept referring to wheel-like vortices...

' (Sanskrit) in Tibetan literature. Khorlo is also used to denote 'mandala

Mandala

Maṇḍala is a Sanskrit word that means "circle". In the Buddhist and Hindu religious traditions their sacred art often takes a mandala form. The basic form of most Hindu and Buddhist mandalas is a square with four gates containing a circle with a center point...

' (Sanskrit; Tibetan: dkyil 'khor).

It appears in the names of some tantric

Vajrayana

Vajrayāna Buddhism is also known as Tantric Buddhism, Tantrayāna, Mantrayāna, Secret Mantra, Esoteric Buddhism and the Diamond Vehicle...

 deities such as Chakrasamvara ('khor-lo bde-mchog, "wheel of great bliss") and Kalachakra

Kalachakra

Kalachakra is a Sanskrit term used in Tantric Buddhism that literally means "time-wheel" or "time-cycles".The spelling Kalacakra is also correct....

 (dus-kyi 'khor-lo, "wheel of time").

With a different connotation, it can also refer to samsara

Samsara (Buddhism)

or sangsara is a Sanskrit and Pāli term, which translates as "continuous movement" or "continuous flowing" and, in Buddhism, refers to the concept of a cycle of birth , and consequent decay and death , in which all beings in the universe participate, and which can only be escaped through...

, or worldly, mundane life, full of suffering (as in "to flow together").