Gentile da Foligno
Encyclopedia
Gentile Gentili da Foligno (died 18 June 1348) was an Italian professor and doctor of medicine, trained at Padua and the University of Bologna
University of Bologna
The Alma Mater Studiorum - University of Bologna is the oldest continually operating university in the world, the word 'universitas' being first used by this institution at its foundation. The true date of its founding is uncertain, but believed by most accounts to have been 1088...

, and teaching probably first at Bologna, then at the University of Perugia
University of Perugia
University of Perugia is a public-owned university based in Perugia, Italy. It was founded in 1308, as attested by the Bull issued by Pope Clement V certifying the birth of the Studium Generale....

, Siena
University of Siena
The University of Siena in Siena, Tuscany is one of the oldest and first publicly funded universities in Italy. Originally called Studium Senese, the University of Siena was founded in 1240. The University has around 20,000 students, nearly half of Siena's total population of around 54,000...

 (1322-24), then Perugia, where his annual stipend was 60 gold florins; he was called to Padua
University of Padua
The University of Padua is a premier Italian university located in the city of Padua, Italy. The University of Padua was founded in 1222 as a school of law and was one of the most prominent universities in early modern Europe. It is among the earliest universities of the world and the second...

 (1325-35) by Ubertino I da Carrara, Lord of Padua, then returned to Perugia for the remainder of his career. He was the first European physician to perform a dissection
Dissection
Dissection is usually the process of disassembling and observing something to determine its internal structure and as an aid to discerning the functions and relationships of its components....

 on a human being (1341), a practice long outlawed by the Christian Church as it compromised the completeness of the body awaiting Resurrection
Resurrection
Resurrection refers to the literal coming back to life of the biologically dead. It is used both with respect to particular individuals or the belief in a General Resurrection of the dead at the end of the world. The General Resurrection is featured prominently in Jewish, Christian, and Muslim...

. Gentile wrote several widely copied and read texts and commentaries, notably his massive commentary covering all five books of the Canon of Medicine by the 11th-century Persian polymath Avicenna
Avicenna
Abū ʿAlī al-Ḥusayn ibn ʿAbd Allāh ibn Sīnā , commonly known as Ibn Sīnā or by his Latinized name Avicenna, was a Persian polymath, who wrote almost 450 treatises on a wide range of subjects, of which around 240 have survived...

, the comprehensive encyclopedia that, in Latin translation, was fundamental to medieval medicine. Long after his death, Gentile da Foligno was remembered in the Nuremberg Chronicle
Nuremberg Chronicle
right|thumbnail|240px|Fifth dayThe Nuremberg Chronicle is an illustrated Biblical paraphrase and world history that follows the story of human history related in the Bible; it includes the histories of a number of important Western cities. Written in Latin by Hartmann Schedel, with a version in...

 (1493) as Subtilissimus rimator verborum Avicenne, "that most subtle investigator of Avicenna's teachings"

Other works by Gentile were De complexione, proportione et dosi medicinarum; Consilium de temporibus partus; De statu hominum; De lepra; De febribus; De balneis; De divisione librorum Galeni; Tractatus de reductione medicinarum; Regimen preservativum; Among these the Consilium, a compilation of therapeutic advice for many diseases. He made commentaries on two works, Carmina de urinarum iudiciis ("Songs of urinary judgements") part of a metrical work, the Carmina medica, that had been composed by Egidius Corbaliensis, and Egidius' De pulsibus ("About pulses").
A mark of the respect in which Gentile's work continued to be held, more than a century after his death, was the rapidity with which they appeared in print, from the Italian presses, beginning in the 1470s.

Gentile's commentary de urinarum iudiciis makes a first attempt to comprehend the physiology of urine formation
Urine
Urine is a typically sterile liquid by-product of the body that is secreted by the kidneys through a process called urination and excreted through the urethra. Cellular metabolism generates numerous by-products, many rich in nitrogen, that require elimination from the bloodstream...

; aided by his dissection of cadavers, Gentile asserted that urine associated with the blood passes per poros euritides ("through the porous tubules
Tubule
A tubule is a very small tube or fistular structure.A system of surface-connected membranes in muscle that enables a nerve impulse to travel to the interior of the muscle fibre.In anatomy, a tubule is a minute tube lined with glandular epithelium....

") of the kidney and is then delivered to the bladder. Commenting on De pulsibus, he connected the relationship between fast pulse rate and urine output and correlated the color of urine with the condition of the heart. For the originality of his thought Mario Timio suggested that Gentile could be indicated as the 'first' cardionephrologist
Nephrology
Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.-Scope of the specialty:...

 in the history of medicine
History of medicine
All human societies have medical beliefs that provide explanations for birth, death, and disease. Throughout history, illness has been attributed to witchcraft, demons, astral influence, or the will of the gods...

.

He prepared a widely-read treatise on the Black Death
Black Death
The Black Death was one of the most devastating pandemics in human history, peaking in Europe between 1348 and 1350. Of several competing theories, the dominant explanation for the Black Death is the plague theory, which attributes the outbreak to the bacterium Yersinia pestis. Thought to have...

, recommending theriac
Theriac
Theriac or theriaca was a medical concoction originally formulated by the Greeks in the 1st century AD and became popular throughout the ancient world as far away as China and India via the trading links of the Silk Route...

among other prophylaxis, but died of the plague himself.
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